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Almon Shiu, Ph.D.

Present Title & Affiliation

Primary Appointment

Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

1988 The University of Texas Health Science Center at Houston Graduate School of Biomedical Sciences, Houston, TX, PHD, Medical Physics
1976 Carnegie Mellon University, Pittsburgh, PA, MS, Medical Physics
1973 Ohio University, Athens, OH, MS, Experimental Nuclear Physics
1970 National Cheng-Kung University, Tainan, Taiwan, BS, Physics

Board Certifications

1990 American Board of Medical Physics in Radiation Physics
1984 American Board of Radiology in Therapeutic Radiological Physics

Experience/Service

Academic Appointments

Associate Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 1999-2006
Assistant Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 1991-1999
Assistant Physicist, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 1988-1991
Senior Medical Physicist, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 1987-1988
Assistant in Physics, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 1985-1987
Chief Medical Physicist, Department of Radiation Oncology, Norfolk General Hospital, Medical Center Hospital, Norfolk, VA,, 1980-1985
Medical Physicist, Department of Radiation Oncology, Norfolk General Hospital, Medical Center Hospital, Norfolk, VA, 1976-1980

Administrative Appointments/Responsibilities

Service Chief, CNS/PEDI Physics Group, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2004-2007

Professional Memberships

American Association of Physicists in Medicine
Member, Radiation Physics Committee, 2008-present
Member, Working Group on Vendor Relations and Product Usability, 2007-present
Member, TG131 Medical Physics Training in Developing Countries in the Region, 2006-present
Member, TG101 Stereotactic Body Radiotherapy, 2006-2010
Awards and Honors Committee, 2005-2007
Member, Membership Committee, 2004-2006
Fellow, 2002-present
Chair, Technology Assessment Subcommittee, 2000-2003
Member, General Medical Physics Committee, 2000-2002
Co-coordinator, AAPM Summer School, 2000
Member, Asian Oceanic Affairs Subcommittee of International Affairs, 1999-present
Member, Continuing Education Committee, 1998-present
Chair, Radiation Therapy Committee, 1996-2003
Member, Radiation Therapy Committee, 1996-2003
American Association of Physicists in Medicine
Member, Training of Radiologists Subcommittee, 1994-1996
American Association of Physicists in Medicine
Member, 1976-present
American College of Medical Physics
Member, 1989-present
American College of Radiology
Member, 1984-present
American Society for Therapeutic Radiology and Oncology
Tachnology Assessment and Outcome Committee, 1999-present
Member, 1990-present
The University of Texas Graduate School of Biomedial Sciences
Member, Medical Physics Program Steering Committee, 1998-2000
Member, 1995-present
Member, Specialized Master Committee, 1995-1997
The University of Texas M. D. Anderson Cancer Center
Member, M.D. Anderson Cancer Center Faculty Senate Clinical Affairs Subcommittee, 1997-present
XKnife Society
Chair, Physics Board of Directors, 1998-2002
Member, 1998-2002

Selected Publications

Peer-Reviewed Original Research Articles
1. Qi ZY, Deng XW, Huang SM, Shiu A, Lerch M, Metcalfe P, Rosenfeld A, Kron T. Real-Time In Vivo dosimetry with MOSFET detectors for seriel tomotherapy of head and neck patients. In Press.
2. Benedict SH, Yenice KM, Galvin JM, Hinson W, Kavanagh B, Keall P, Lovelock M, Meeks S, Papiez L, Purdie T, Sadagopan R, Schell MC, Salter B, Schlesinger DJ, Shiu AS, Solberg T, Song DY, Stieber V, Timmerman R, Tome WA, Verellen D, Wang L, Yin F. Stereotactic body radiation therapy: the report of AAPM task group 101. Med Phys 37(8):4078-4101, 8/2010.
3. Du W, Yang JN, Chang EL, Luo D, McAleer MF, Shiu A, Martel MK. A quality assurance procedure to evaluate cone-beam CT image center congruence with the radiation isocenter of a linear accelerator. JACMP 11(4):15-26, 2010.
4. Sahgal Ma L, Cozzi L, Chang E, Shiu A, Letourneau D, Yin FF, Fogliata A, Kaissl W, Hyde D, Laperiere NJ, Shrieve DC, Larson DA. Apparatus-dependent dosimetric differences in spine stereotactic body radiotherapy. Technol Cancer Res Treat 9(6):563-574, 2010.
5. Shiu AS, Wang C, Ye J, Meier R, Mehta V, Vermeulen S, Chang E. Dose distribution comparison for the treatment of spinal and lung metastases using CyberKnife versus IMRT stereotactic body radiotherapy using LINAC/CT-on-Rails Unit. Radiosurgery 7:56-65, 2010.
6. Parker BC, Shiu A, White RA, Maor M, Dong L, Liu HH. Pretreatment verification of IMSRT using electronic portal imaging and Monte Carlo calculations. Technol Cancer Res Treat 8(6):413-423, 12/2009. PMID: 19925025.
7. Chang EL, Wefel JS, Hess KR, Allen PK, Lang FF, Kornguth DG, Arbuckle RB, Swint JM, Shiu AS, Maor MH, Meyers CA. Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irratiation: a randomized controlled trial. Lancet Oncol 10(11):1037-44, 11/2009. e-Pub 10/2/2009. PMID: 19801201.
8. Sahgal A, Ma L, Chang E, Shiu A, Larson DA, Laperriere N, Yin FF, Tsao M, Menard C, Basran PS, Létourneau D, Heydarian M, Beachey D, Shukla V, Cusimano M, Hodaie M, Zadeh G, Bernstein M, Schwartz M. Advances in technology for intracranial stereotactic radiosurgery. Technol Cancer Res Treat 8(4):271-80, 8/2009. PMID: 19645520.
9. Wang H, Shiu A, Wang C, O'Daniel J, Mahajan A, Woo S, Liengsawangwong P, Mohan R, Chang EL. Dosimetric effect of translational and rotational errors for patients undergoing image-guided stereotactic body radiotherapy for spinal metastases. Int J Radiat Oncol Biol Phys 71(4):1261-1271, 7/2008. e-Pub 5/2008. PMID: 18485614.
10. Yom S, Frija EK, Mahajan A, Chang E, Klein K, Shiu AS, Ohrt J, Woo S. Field-in-Field Technique with Intrafractionally Modulated Junction Shifts for Craniospinal Irradiation. International Journal of Radiation Oncology Biology Physics 69(4):1193-1198, 11/2007. PMID: 17967308.
11. Chang EL, Shiu AS, Mendel E, Mathews LA, Mahajan A, Allen PK, Weinberg JS, Brown BW, Wang XS, Woo SY, Cleeland C, Maor MH, Rhines LD. Phase I/II study of stereotactic body radiation therapy for spinal metastasis and its pattern of failure. J Neurosurg Spine 7(2):151-160, 8/2007. PMID: 17688054.
12. Wang C, Shiu AS, Lii M, Chang EL. Automatic Target Localization and Verification for On-Line Image-Guided Stereotactic Body Radiotherapy of the Spine. Technol Cancer Res Treat 6(3):187-96, 6/2007. PMID: 17535027.
13. Chang EL, Wefel JS, Maor MH, Hassenbusch SJ, 3rd, Mahajan A, Lang FF, Woo SY, Mathews LA, Allen PK, Shiu AS, Meyers CA. A Pilot Study of Neurocognitive Function in Patients with One to Three New Brain Metastases Initially Treated with Stereotactic Radiosurgery Alone. Neurosurgery 60(2):277-83; discussion 283-4, 2/2007. PMID: 17290178.
14. Akyurek S, Chang EL, Mahajan A, Hassenbusch SJ, Allen PK, Matthews LA, Shiu AS, Maor MH, Woo SY. Stereotactic radiosurgical treatment of cerebral metastases arising from breast cancer. Am J Clin Oncol 30(3):310-4, 2007. PMID: 17551311.
15. Shiu AS, Wang C, Woo S, Wang H. Image-guided Non-Invasive Stereotactic Radiosurgery. International Conference on Quality Assurance and New Technology in Radiation Medicine. IAEA-CN 146:18-19, 2006.
16. Mahajan A, McCutcheon IE, Suki D, Chang EL, Hassenbusch SJ, Weinberg JS, Shiu A, Maor MH, Woo SY. Case-control study of stereotactic radiosurgery for recurrent glioblastoma multiforme. J Neurosurg 103(2):210-7, 8/2005. PMID: 16175848.
17. Sahoo N, Kazi AM, Cho, SH, Sadagopan R, Shiu AS. Effect of Detector Properties on Beam Profile Measurement of Small Field MV X-ray Beams. Biomedizinische Technik 50:741-742, 1/2005.
18. Chang EL, Shiu AS, Lii MF, Rhines LD, Mendel E, Mahajan A, Weinberg JS, Mathews LA, Brown BW, Maor MH, Cox JD. Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases. Int J Radiat Oncol Biol Phys 59(5):1288-94, 8/2004. PMID: 15275711.
19. Selek U, Chang EL, Hassenbusch SJ, 3rd, Shiu AS, Lang FF, Allen P, Weinberg J, Sawaya R, Maor MH. Stereotactic radiosurgical treatment in 103 patients for 153 cerebral melanoma metastases. Int J Radiat Oncol Biol Phys 59(4):1097-106, 7/2004. PMID: 15234044.
20. Shiu AS, Chang EL, Ye JS, Lii M, Rhines LD, Mendel E, Weinberg J, Singh S, Maor MH, Mohan R, Cox JD. Near simultaneous computed tomography image-guided stereotactic spinal radiotherapy: an emerging paradigm for achieving true stereotaxy. Int J Radiat Oncol Biol Phys 57(3):605-13, 11/2003. PMID: 14529763.
21. Chang EL, Hassenbusch SJ, Shiu AS, Lang FF, Allen PK, Sawaya R, Maor MH. The role of tumor size in the radiosurgical management of patients with ambiguous brain metastases. Neurosurgery 53(2):272-80; discussion 280-1, 8/2003. PMID: 12925241.
22. Shiu AS, Parker B, Ye J, Lii J. An Integrated Treatment Delivery System for CSRS and CSRT and Clinical Applications. JACMP 4:261-273, 2003.
23. Chang EL, Hassenbusch III SJ, Shiu AS, Lang FF, Allen PK, Sawaya R, Maor MH. Determination of a New Cut-Point (0.5cm3) for Local Control of Small Brain Metastases: Implications for Optimum Timing of Stereotactic Radiosurgery. Neurosurgery 53:272-281, 2003.
24. Parker BC, Shiu AS, Maor MH, Lang FF, Liu HH, White RA, Antolak JA. PTV margin determination in conformal SRT of intracranial lesions. J Appl Clin Med Phys 3(3):176-89, 2002. PMID: 12132939.
25. Boyd RA, Hogstrom KR, Antolak JA, Shiu AS. A measured data set for evaluating electron-beam dose algorithms. Med Phys 28(6):950-8, 6/2001. PMID: 11439491.
26. Maor MH, Dubey P, Tucker SL, Shiu AS, Mathur BN, Sawaya R, Lang FF, Hassenbusch SJ. Stereotactic radiosurgery for brain metastases: results and prognostic factors. Int J Cancer 90(3):157-62, 6/2000. PMID: 10900428.
27. Dong L, Shiu A, Tung S, Hogstrom K. A pencil-beam photon dose algorithm for stereotactic radiosurgery using a miniature multileaf collimator. Med Phys 25(6):841-50, 6/1998. PMID: 9650171.
28. Shiu AS, Kooy HM, Ewton JR, Tung SS, Wong J, Antes K, Maor MH. Comparison of miniature multileaf collimation (MMLC) with circular collimation for stereotactic treatment. Int J Radiat Oncol Biol Phys 37(3):679-88, 2/1997. PMID: 9112467.
29. Dong L, Shiu A, Tung S, Boyer A. Verification of radiosurgery target point alignment with an electronic portal imaging device (EPID). Med Phys 24(2):263-7, 2/1997. PMID: 9048367.
30. Shiu AS, Tung SS, Gastorf RJ, Hogstrom KR, Morrison WH, Peters LJ. Dosimetric evaluation of lead and tungsten eye shields in electron beam treatment. Int J Radiat Oncol Biol Phys 35(3):599-604, 6/1996. PMID: 8655385.
31. Bindal AK, Bindal RK, Hess KR, Shiu A, Hassenbusch SJ, Shi WM, Sawaya R. Surgery versus radiosurgery in the treatment of brain metastasis. J Neurosurg 84(5):748-54, 5/1996. PMID: 8622147.
32. Shiu AS, Tung SS, Nyerick CE, Ochran TG, Otte VA, Boyer AL, Hogstrom KR. Comprehensive analysis of electron beam central axis dose for a radiotherapy linear accelerator. Med Phys 21(4):559-66, 4/1994. PMID: 8058023.
33. Tung SS, Shiu AS, Starkschall G, Morrison WH, Hogstrom KR. Dosimetric evaluation of total scalp irradiation using a lateral electron-photon technique. Int J Radiat Oncol Biol Phys 27(1):153-60, 9/1993. PMID: 8365936.
34. Shiu AS, Tung S, Hogstrom KR, Wong JW, Gerber RL, Harms WB, Purdy JA, Ten Haken RK, McShan DL, Fraass BA. Verification data for electron beam dose algorithms. Med Phys 19(3):623-36, 5/1992. PMID: 1508101.
35. Kurup RG, Hogstrom KR, Otte VA, Moyers MF, Tung S, Shiu AS. Dosimetric evaluation of a two-dimensional, arc electron, pencil-beam algorithm in water and PMMA. Phys Med Biol 37(1):127-44, 1992. PMID: 1741418.
36. Shiu AS Hogstrom KR. Dose in bone and tissue near bone-tissue interface from electron beam. Int J Radiat Oncol Biol Phys 21:695-702, 8/1991. PMID: 1869463.
37. Starkschall G, Shiu AS, Bujnowski SW, Wang LL, Low DA, Hogstrom KR. Effect of dimensionality of heterogeneity corrections on the implementation of a three-dimensional electron pencil-beam algorithm. Phys Med Biol 36:207-227, 2/1991. PMID: 2008447.
38. Shiu AS, Hogstrom KR. Pencil-Beam Redefinition Algorithm for Electron Dose Distributions. Medical Physics 18:7-18, 1991.
39. Hogstrom KR, Boyer AL, Shiu AS, Ochran TG, Kirsner SM, Krispel F, Rich T. Design of metallic electron beam cones for an intraoperative therapy linear accelerator. Int J Radiat Oncol Biol Phys 18(5):1223-32, 5/1990. PMID: 2347729.
40. Shiu AS, Otte VA, Hogstrom KR. Measurement of dose distributions using film in therapeutic electron beams. Med Phys 16(6):911-5, 11/1989. PMID: 2511400.
41. Hogstrom KR, Kurup RG, Shiu AS, Starkschall G. A two-dimensional pencil-beam algorithm for calculation of arc electron dose distributions. Phys Med Biol 34:315-41, 3/1989. PMID: 2494678.
42. Shiu AS, Hogstrom KR, Janjan NA, Fields RS, Peters LJ. Technique for verifying treatment fields using portal images with diagnostic quality. Int J Radiat Oncol Biol Phys 13:1589-94, 10/1987. PMID: 3114184.
43. Hatjigiorgis CG, Shiu AS, Fleming TJ, Kramer DC. Influence of calcium phosphate hydroxylapatite on dose distribution in electron beam radiation therapy. Int J Oral Maxillofac Implants 2:65-8, 1987. PMID: 2830186.
44. Wang, XS, Rhines LD, Shiu AS, Yang JN, Selek U, Gning I, Liu P, Allen PK, Azeem SS, Brown PD, Weksberg DC, Cleeland CS, Chang EL. A prospective analysis of the clinical effects of stereotactic body radiation therapy in cancer patients with spinal metastases without spinal cord compression. Lancet Oncology. Submitted.
45. Weksberg DC, Palmer MB, Rebueno N, Vu K, Sharp HJ, Luo D, Yang J, Shiu A, McAleet MF, Brown P, Chang EL. Generalizable class solutions for treatment planning of spinal stereotactic body radiation therapy. Int. J of Radiat Oncol Biol Phys. Submitted.
Other Articles
1. Shiu AS. Three-Dimensional Electron Beam Dose Calculation. Ph.D. dissertation, 1988.

Abstracts
1. Caruthers D, Ibbott G, Shiu A, Chang E, White R, Followill D. Commissioning an anthropomorphic spine and lung phantom for remote quality assurance of spinal radiosurgery. Med Phys 37(6), 6/2010.
2. Du W, Yang J, Chang E, Luo D, McAleer M, Shiu A, Martel M. Congruence of cone-beam CT image center with the radiation isocenter of a linear accelerator. Med Phys 37(6):3162, 6/2010.
3. Shiu AS, Wang H, Je J, Contrutz C, Meier R, Mehta V, Vermeulen S, Chang E,. Dose Distribution Comparison for the Treatment of Lung and Spinal Metastases using CyberKnife versus IMRT Stereotactic Body Radiotherapy. Medical Physics 34(6):2438-2439, 2007.
4. Wang C, Shiu A, Lii M, Chang EC. Automation of Image Registration and Verification for Image-Guided Stereotactic Body Radiotherapy. Med. Phys 32(6):1943, 2005.
5. Shiu A, Wang C, Lii M, Chang EC. Image-Guided Radiotherapy Feasibility Study Using Kilo-Voltage Cone-Beam CT Images for Patient Alignment Verification. Med. Phys 32(6):1933, 2005.
6. Shiu A Wang C. Implementation of a 6D Robotic Couch-Top for the Automation of Image-Guided Brain SRS and Spinal SRT. International Journal Radiation Oncology Biology Physics, 2005.
7. Shiu AS, Chang E, Ye J, Dong L, Lii M, Liu H, Maor M, Parker L, Court L, Mohan R. Image-Guided Stereotactic Intensity Modulated Radiosurgery/Radiotherapy. Med Phys 29:1239, 2002.
8. Parker B, Shiu AS, Liu H. Small-Field Dosimetry with multiple Detectors and Monte Carlo Calculations. Med Phys 29(6):1372, 2002.
9. Shiu AS, Chang E, Lii J, Ye J, Maor M. Conformity of Dose Distribution and setup Accuracy comparable to Invasive Head Frame Using a MLC and a Unique Positioning Device with GTC frame for SRT. International Journal Radiation Oncology Biology Physics, 2001.
10. Parker B, Shiu AS, Antolak R, White R. Quantification of Uncertainties for PTV Margin Determination in Conformal Stereotactic Radiotherapy of Intracranial Lesions. Med Phys 28:1303, 2001.

Book Chapters
1. Chang EL, Shiu AS. Cumulative Dose Distribution Analysis for CT-Image-Guided Stereotactic Radiation Therapy for Spine Metastases Patients. In: Principal and Practice of Stereotactic Radiosurgery, 455-458, 2008.
2. Hogstrom KR, Antolak, JA, Hanson WF, Horton JL, Rosen II, Shiu AS, Starkschall G. Clinical Radiation Physics. In: Radiation oncology: rationale, technique, results. Mosby, 63-96, 2003.
3. Ang KK, Milias L, Shiu AS. General Principles of Radiation Therapy for Cancer of the Head and Neck. In: Cancer of the Head and Neck. Saunders, 717-735, 2003.
4. Shiu AS, Parker B, Ye J, Lii J. An Integrated Treatment Delivery System for SRS and SRT. In: XIIIth ICCR Conference Proceedings, May 2000, 341-343, 2000.
5. Shiu AS, Wong J, Ewton JE, Rittichier HE, Tung SS, Dong L. Computer-controlled Miniature Multileaf Collimator. In: XIIth ICCR Conference Proceedings, May 1997, 83-85, 1997.
6. Hogstrom KR, Starkschall G, Shiu AS. Dose Calculation Algorithms for Electron Beams. In: Advanced in Radiation Oncology Physics –1990 Proceedings of the Summer School of the AAPM. American Institute of Physics: New York, 1991.
7. Hogstrom KR, Kirsner SM, Kurup RG, Shiu AS, Moyers MF. In: Operational Characteristics of Siemens Mevatron for Electron Arc Beam. In Proceedings of 1987 Therapy Users Conference: Scottsdale, 185-214, 1987.
8. Shiu AS Hogstrom KR. A Pencil Beam Redefinition Algorithm for Electron Dose Distributions. In: Proceedings of the Ninth International Conference on the use of Computers in Radiation Therapy, Scheveningen, The Netherlands. Scheveningen: The Netherlands, 69-72, 1987.

Books (edited and written)
1. Shiu AS, Mellenberg DE. General Practice of Radiation Oncology Physics in the 21st Century, 2000 Summer School Proceedings Northern Illinois University July 29 – August 1, 2000. Medical Physics Publishing: Madison, 2000.

Last updated: 12/15/2011