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Anita Mahajan

Present Title & Affiliation

Primary Appointment

Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Medical Director Proton Therapy Center, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

1992 McGill University, Montreal, Quebec, Canada, MD, M.D., C.M., Medicine
1988 University of Toronto, Toronto, Canada, BS, Biochemistry

Postgraduate Training

1/1996-1/1997 Proton Fellowship, Massachusetts General Hospital, Boston, MA, Dr. J.E. Munzenrider
1/1993-1/1996 Radiation Oncology Residency, McGill University, Montreal, Quebec, Canada, Dr. C. Freeman
1/1992-1/1993 Internal Medicine Internship, McGill University/Jewish General Hospital, Montreal, Quebec, Canada

Board Certifications

9/2001 American Board of Radiology
6/1996 Royal College Specialty Examination in Radiation Oncology

Experience/Service

Academic Appointments

Associate Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/2005-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Suki D, Hatiboglu MA, Patel AJ, Weinberg JS, Groves MD, Mahajan A, Sawaya R. Comparative risk of leptomeningeal dissemination of cancer after surgery or stereotactic radiosurgery for a single supratentorial solid tumor metastasis. Neurosurgery 64(4):664-74, 4/2009. PMID: 19197219.
2. Wang H, Shiu A, Wang C, O'Daniel J, Mahajan A, Woo S, Liengsawangwong P, Mohan R, Chang EL. Dosimetric effect of translational and rotational errors for patients undergoing image-guided stereotactic body radiotherapy for spinal metastases. Int J Radiat Oncol Biol Phys 71(4):1261-71, 7/15/2008. PMID: 18485614.
3. Amini E, Roffidal T, Lee A, Fuller GN, Mahajan A, Ketonen L, Kobrinsky N, Cairo MS, Wells RJ, Wolff JE. Central neurocytoma responsive to topotecan, ifosfamide, carboplatin. Pediatr Blood Cancer 51(1):137-40, 7/2008. PMID: 18338396.
4. Kadan-Lottick NS, Dinu I, Wasilewski-Masker K, Kaste S, Meacham LR, Mahajan A, Stovall M, Yasui Y, Robison LL, Sklar CA. Osteonecrosis in Adult Survivors of Childhood Cancer: A report from the Childhood Cancer Survivor Study. J Clin Oncol 26(18):3038-45, 6/20/2008. PMID: 18565890.
5. Mahajan A, Woo SY, Kornguth DG, Hughes D, Huh W, Chang EL, Herzog CE, Pelloski CE, Anderson P. Multimodality treatment of osteosarcoma: radiation in a high-risk cohort. Pediatr Blood Cancer 50(5):976-82, 5/2008. PMID: 18213710.
6. Masoudi A, Amini E, Wolff JE, Fuller GN, Ketonen L, Mahajan A. Shrinkage of germinoma by dexamethasone only. Pediatr Blood Cancer 50(5):1079, 5/2008. PMID: 18000859.
7. Zhang M, Segerer F, Ketonen L, Mahajan A, Wolff J. Prediction of tumour regrowth of pontine glioma using a two-term model. Anticancer Res 28(2A):741-9, Mar-Apr, 3/2008. PMID: 18507015.
8. Yom SS, Frija EK, Mahajan A, Chang E, Klein K, Shiu A, Ohrt J, Woo S. Field-in-field technique with intrafractionally modulated junction shifts for craniospinal irradiation. Int J Radiat Oncol Biol Phys 69(4):1193-8, 11/15/2007. PMID: 17967308.
9. Akyurek S, Chang EL, Mahajan A, Hassenbusch SJ, Allen PK, Mathews LA, Shiu AS, Maor MH, Woo SY. Stereotactic radiosurgical treatment of cerebral metastases arising from breast cancer. Am J Clin Oncol 30(3):310-4, 6/2007. PMID: 17551311.
10. Chang EL, Wefel JS, Maor MH, Hassenbusch SJ, 3rd, Mahajan A, Lang FF, Woo SY, Mathews LA, Allen PK, Shiu AS, Meyers CA. A pilot study of neurocognitive function in patients with one to three new brain metastases initially treated with stereotactic radiosurgery alone. Neurosurgery 60(2):277-83; discussion 283-4, 2/2007. PMID: 17290178.
11. Chang EL, Akyurek S, Avalos T, Rebueno N, Spicer C, Garcia J, Famiglietti R, Allen PK, Chao KS, Mahajan A, Woo SY, Maor MH. Evaluation of peritumoral edema in the delineation of radiotherapy clinical target volumes for glioblastoma. Int J Radiat Oncol Biol Phys 68(1):144-50, 2/2007. PMID: 17306935.
12. Hermanto U, Frija EK, Lii MJ, Chang EL, Mahajan A, Woo SY. Intensity-modulated radiotherapy (IMRT) and conventional three-dimensional conformal radiotherapy for high-grade gliomas: Does IMRT increase the integral dose to normal brain? Int J Radiat Oncol Biol Phys 67(4):1135-44, 1/2007. PMID: 17208388.
13. Kennedy-Nasser AA, Leung KS, Mahajan A, Weiss HL, Arce JA, Gottschalk S, Carrum G, Khan SP, Heslop HE, Brenner MK, Bollard CM, Krance RA. Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic anemia. Biol Blood Marrow Transplant 12(12):1277-84, 12/2006. PMID: 17162209.
14. Nguyen QN, Chang EL, Allen PK, Maor MH, Ater JL, Mahajan A, Wolff JE, Weinberg JS, Woo SY. Focal and craniospinal irradiation for patients with intracranial germinoma and patterns of failure. Cancer 107(9):2228-36, 11/2006. PMID: 17019739.
15. Akyurek S, Chang EL, Yu TK, Little D, Allen PK, McCutcheon I, Mahajan A, Maor MH, Woo SY. Spinal myxopapillary ependymoma outcomes in patients treated with surgery and radiotherapy at M.D. Anderson Cancer Center. J Neurooncol 80(2):177-83, 11/2006. PMID: 16648988.
16. Hu C, Chang EL, Hassenbusch SJ, Allen PK, Woo SY, Mahajan A, Komaki R, Liao Z. Nonsmall cell lung cancer presenting with synchronous solitary brain metastasis. Cancer 106(9):1998-2004, 5/1/2006. PMID: 16572401.
17. Lee CT, Bilton SD, Famiglietti RM, Riley BA, Mahajan A, Chang EL, Maor MH, Woo SY, Cox JD, Smith AR. Treatment planning with protons for pediatric retinoblastoma, medulloblastoma, and pelvic sarcoma: how do protons compare with other conformal techniques? Int J Radiat Oncol Biol Phys 63(2):362-72, 10/2005. PMID: 16168831.
18. Mahajan A, McCutcheon IE, Suki D, Chang EL, Hassenbusch SJ, Weinberg JS, Shiu A, Maor MH, Woo SY. Case-control study of stereotactic radiosurgery for recurrent glioblastoma multiforme. J Neurosurg 103(2):210-7, 8/2005. PMID: 16175848.
19. Chang EL, Selek U, Hassenbusch SJ, 3rd, Maor MH, Allen PK, Mahajan A, Sawaya R, Woo SY. Outcome variation among "radioresistant" brain metastases treated with stereotactic radiosurgery. Neurosurgery 56(5):936-45; discussion 936-45, 5/2005. PMID: 15854241.
20. Pelloski CE, Mahajan A, Maor M, Chang EL, Woo S, Gilbert M, Colman H, Yang H, Ledoux A, Blair H, Passe S, Jenkins RB, Aldape KD. YKL-40 expression is associated with poorer response to radiation and shorter overall survival in glioblastoma. Clin Cancer Res 11(9):3326-34, 5/2005. PMID: 15867231.
21. Chang EL, Shiu AS, Lii MF, Rhines LD, Mendel E, Mahajan A, Weinberg JS, Mathews LA, Brown BW, Maor MH, Cox JD. Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastases. Int J Radiat Oncol Biol Phys 59(5):1288-94, 8/2004. PMID: 15275711.
22. Miller KB, Roberts TF, Chan G, Schenkein DP, Lawrence D, Sprague K, Gorgun G, Relias V, Grodman H, Mahajan A, Foss FM. A novel reduced intensity regimen for allogeneic hematopoietic stem cell transplantation associated with a reduced incidence of graft-versus-host disease. Bone Marrow Transplant 33(9):881-9, 5/2004. PMID: 14990986.

Abstracts

1. McGovern S, Mahajan A, Wang J, Woo SY. Diffusion tensor imaging for target volume delineation for patients with high-grade glioma. American Radium Society, 5/2009.
2. Li L , Nagel P, Ketonen L, Mahajan A, Wolff J. Improved Response of Pontine Glioma with Concurrent Radiochemotherapy: Results of a Retrospective Image Analysis. World Federation of Neuro-Oncology 3rd Annual Meeting, 5/2009.
3. Mahajan A, Chintagumpala M, Wolff J, Ater J, Woo SY. Early MRI Changes in the Brain after Proton Radiotherapy for Intracranial Neoplasms. Radiological Society of North America 2008, 11/2008.
4. Huh WW, Mahajan A, Munsell M, Cornelius K, Patel S, and Ater J. Abnormal Body Mass Index in Adult Survivors of Childhood Sarcomas, 2008, 9/2008.
5. Baxter P, Oktay H, Paulino A, Whitehead W, Dauser R, Kornguth D, Mahajan A, Edmond J, Okcu MF, Chintagumpala M. Craniopharyngioma patients are at increased risk for obesity after therapy. 13th ISPNO, Chicago, 7/2008.
6. Nguyen Q, Mahajan A, Kornguth D, Chintagumpala M, Wolff J, Chang E, Allen P, Woo S. The evaluation of bone marrow toxicities associated with electron, photon, or proton craniospinal irradiation in pediatric patients. 13th ISPNO, Chicago, 7/2008.
7. Lang FF, McPherson C, Suki D, Chang E, Maro M, Sawaya R, Mahajan A. Adjuvant Radiotherapy after surgical resection of slingle brain metastases: An analysis of 358 ptients by primary tumor site. Society of NeuroOncology, Dallas 9:588, 10/2007.
8. Mahajan A, Dong L, Prabhu S, Wang C, Zhang Y, Lifei Z, Meyers C, Woo S. Application of deformable image registration to hippocampal doses and neurocognitive outcomes. Society of Neuro Oncology, Dallas 9:583, 10/2007.
9. Wolff J, Wrede B, Peters O, Gopalakrishnan V, Mahajan A, Weinberg A, Paulus W, Wang X, Thall P. Choroid plexus tumors: A planet wide approach with no age limits--Interm report 03-2007. Society of Neuro Oncology, Dallas 9:538, 10/2007.
10. Shaw S, Sherman S, Mahajan A. Intracranial Metastases and Thyroid Carcinoma: A 14 Year Experience at a Single Institution. The Endocrine Society's 89th Annual Meeting, 5/2007.
11. Kornguth D, Mahajan A, Frija A, Chang E, Pelloski C, Woo S. Shape variability of craniopharyngioma as measured on CT-on-rails during radiotherapy treatment. IJROBP 66:s259, 11/2006.
12. Gilbert M, Gonzalez J, Hunter K, Hess, chang E, Puduvalli V, Groves M, Colman H, Conrad C, Levin V, Woo S, Mahajan A, Hsu S, de Groot J, Yun W. A phase I study for a factorial design of donse-dense temozolomide aloe and in combination with permutations of thalidomide, isotretinoin and/or celecoxib as post-chemoradiation adjuvant therapy for newly diagnosed GBM. Society of Neuro Oncology, Orlando, 10/2006.
13. Mahajan A, Chang EL, Weinberg JS, Hassenbusch SJ, Maor MH, Woo SY. The Evolution of Magnetic Resonance Imaging Changes Over Time After Stereotactic Radiosurgery for Intracranial Metastasis. American Radium Society (ARS) 87th Annual Meeting, Hotel Arts Barcelona, Spain, 4/2005.
14. Pelloski CE, Maor MH, Chang EL, Mahajan A, Colman H, Yang H, Ledoux A, Aldape KD. YKL-40 Expression Correlates with Poor Radiation Response and Decreased Overall Survival in Glioblastoma: A Clinicopathologic Study of 279 Patients. Ninth Annual Meeting of the Society for Neuro-Oncology 6:PA-19, 11/2004.
15. Chang EL, Shiu AS, Lii M-F, Mendel E, Mahajan A, Weinberg JS, Woo SY, Rhines L. Phase I Clinical Evaluation of Near-Simultaneous Computed Tomographic Image-Guided Stereotactic Radiotherapy for Spinal Metastases. American Association of Neurological Surgeons and Congress of Neurological Surgeons Section on Tumors 6th Biennial Satellite Symposium, Palace Hotel, San Francisco, CA. (Oral Presentation), 10/2004.
16. Chang EL, Wefel JS, Meyers CA, Mahajan A, Mathews LA, Smythe L, Allen PK, Hassenbusch SJ, Maor MH. Prospective Neurocognitive Evaluation of Patients with 1 to 3 Newly Diagnosed Brain Metastases Treated with Stereotactic Radiosurgery Alone. (Oral Presentation). 46th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Atlanta, GA, 10/2004.
17. Pelloski CE, Maor MH, Chang EL, Mahajan A, Ozburn NC, Aldape KD. Increased P53 Immunoreactivity is Associated with Delayed Treatment Response in Patients with Subtotally Resected Glioblastoma. American Radium Society Proceedings, 86th Annual Meeting, 2004.
18. Chang EL, Selek U, Hassenbusch SJ, Mahajan A, Maor MH. Outcome May Differ by Histology among So-Called “Radioresistant” Brain Metastasis Treated with Stereotactic Radiosurgery. American Radium Society Proceedings, 86th Annual Meeting, 2004.
19. Mahajan A, McCutcheon IE, Chang EL, Maor MH. Stereotactic Radiosurgery for Recurrent Glioblastoma Multiforme. American Radium Society Proceedings, 86th Annual Meeting, 2004.
20. Pelloski CE, Maor MH, Chang EL, Mahajan A, Colman H, Yang H, Ozburn N, Aldape, KA. The Correlation of YKL-40 Expression With Radiation Response and Overall Survival in Patients With Subtotally Resected Glioblastoma. American Society of Therapeutic Radiation Oncology 46th Annual Meeting, 2004.
21. Petropoulos D, Worth LL, Mullen CA, Mahajan A, Choroszy M, Chan KW. Total body irradiation, Fludarabine, Melphalan and allogeneic hematopoietic stem cell transplantation for advanced pediatric hematologic malignancies. American Society of Hematology Proceedings, 46th Annual Meeting, 2004.
22. Lee CT, Bilton SD, Famiglietti RM, Riley BA, Mahajan A, Chang EL, Maor MH, Smith AR. Treatment Planning with Protons for Pediatric Retinoblastoma, Medulloblastoma, and Pelvic Sarcomas: How do Protons Compare with Other Conformal Techniques? . Radiological Society of North America, 2004.

Book Chapters

1. Mahajan A. Malignant Glioma. In: Principles and Practice of Chemoradiation. Ed(s) 2. In Press.
2. Woo SY, Mahajan A. In: Neuro-oncology The essentials, 2. Ed(s) Bernstein M, Berger M. Thieme Medical Publishers, 2008.
3. Janjan N, Mahajan A, Chang EL. Spinal cord compression. In: Textbook of Palliative Medicine. Hodder Arnold Publisher: London, 817-834, 2006.
4. Mahajan A. Concepts and Clinical Applications. Part III. Central Nervous System, Skull Base and Paraspinal Tumors. In: IMRT Handbook: Foundations and Clinical Applications. Springer-Verlag: Berlin-Heidelberg-New York, 2005.
5. Herzog CE, Mahajan A, Lewis VO. Ewing's Sarcoma. In: Pediatric Oncology. Ed(s) Chan KW, Raney RB. Springer Science+Business Media Inc. New York, 121-140, 2005.

Books (edited and written)

1. MD Anderson Faculty. Ed(s) DeMonte F, Gilber M, Mahajan A, McCutcheon I. Tumors of the Brain and Spine. In: MD Anderson Cancer Care Series, 1. Springer Science+Business Media LLC: New York, 2007.

Grant & Contract Support

Title: Integrating Cancer Prevention, Intervention, and Survivorship: Toward a Personalized Approach to Radiotherapy Modality Selection and Surveillance in Pediatric Oncology.
Funding Source: N/A
Role: Co-Investigator
Principal Investigator: Wayne D Newhauser
Duration: 9/1/2010 - 9/30/2012
 
Title: Risk of Secondary Malignancy in Pediatric Patients treated with Protons for Medulloblastoma or Hodgkins Disease
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Wayne Newhauser
Duration: 10/2008 - present
 
Title: Optimizing Progon Radiation Therapy Core A: Administrative Core
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Thomas DeLaney
Duration: 9/25/2008 - 7/31/2014
 
Title: Gliasite Registry
Funding Source: Proxima Therapeutics, Inc
Role: Principal Investigator
Duration: 12/6/2004 - 12/31/2007
 
Title: Phase I Study of Vioxx and Radiation Therapy for Brainstem Glioma in Children and Adults
Funding Source: The University of Texas M. D. Anderson Cancer Center
Role: Collaborator
Principal Investigator: Eric Chang, M.D
Duration: 9/19/2001 - 1/1/2006

Last updated: 8/20/2013