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Ashok J Kumar, M.D.

Present Title & Affiliation

Primary Appointment

Professor, Senior Neuroradiologist/Head & Neck Radiologist - Specialized in Brain Tumor Imaging, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX

Bio Statement

Dr. Ashok J Kumar joined MD Anderson Cancer Center, Houston, TX in the year 1992 as Professor of Radiology and Senior Neuroradiologist/Head & Neck Radiologist. Prior to joining MD Anderson Cancer Center, he worked at The John Hopkins Hospital, Baltimore, MD as a Neuroradiologist from 1974 to 1991, and assumed the role of Director of Magnetic Resonance Imaging at St. Joseph’s Hospital, Towson, MD from 1991 to 1992. Dr. Kumar is a board certified radiologist with added qualification in Neuroradiology. As a Neuroradiologist and Head & Neck Radiologist at MD Anderson Cancer Center, his expertise includes diagnosis of brain tumors, spinal cord tumors, and Head & Neck tumors using CT Imaging and Magnetic Resonance Imaging. His special clinical and research interests include use of advanced Magnetic Resonance Imaging in differentiating brain tumors from therapy effects. Dr. Kumar’s other area of clinical and research include providing pre-operative surgical planning with use of functional Magnetic Resonance Imaging (fMRI) and Diffusion Tensor Imaging to identify eloquent areas of the brain, such as, motor functions and language control areas in patients with brain tumors. Dr. Kumar has published several articles related to brain tumors and post-radiation effects in the brain. Dr. Kumar is actively involved in teaching Residents in Radiology and Neuroradiology Fellows. He has received teacher of the Year award from University of Texas, Houston, TX Radiology Residents in the year 2001 and 2006. He is an active member of MD Anderson’s Brain Tumor Center.

Research Interests

New techniques in functional Magnetic Resonance Imaging and Diffusion Tensor Imaging to identify eloquent areas of the brain, such as motor functions and language control areas in patients with brain tumors.

Clinical Interests

Advanced Magnetic Resonance Imaging in differentiating brain tumors from therapy effects.  Providing pre-operative surgical planning with  use of functional Magnetic Resonance Imaging and Diffusion Tensor Imaging to identify eloquent areas of the brain, such as motor functions and language control areas in patients with brain tumors.

Education & Training

Degree-Granting Education

1966 Madras Medical College, Madras, South India, India, MD, Medicine

Postgraduate Training

1972-1974 Fellowship, New York University Medical Center, New York, NY
1969-1972 Clinical Residency, Northwestern University Medical Center, Chicago, IL
1968-1969 Clinical Internship, General Surgery, Cook County Hospital, Chicago, IL
1966-1967 Clinical Internship, Government General Hospital, Madras, South India, India

Board Certifications

2005 Recertification in Neuroradiology Maintenance of Certification American Board Examination
1995 American Board of Radiology with Added Qualification in Neuroradiology
1977 American Board of Radiology

Experience/Service

Academic Appointments

Professor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 1992-present
Associate Professor, Otolaryngonology/Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 1984-1992
Associate Professor, Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, 1984-1992
Assistant Professor, Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 1981-1992
Assistant Professor, Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, 1974-1984
Instructor, New York University Medical Center, New York, NY, 1973-1974

Administrative Appointments/Responsibilities

Graduate Medical Education Committee, Chair, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 10/2011-present
Section Chief of Neuroradiology and Head-Neck Radiology, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 10/2007-8/2015
Director of MRI, St. Joseph Hospital, Towson, MD, 7/1991-4/1992
Acting Co-Director of the Neuroradiology Division, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, 7/1987-6/1988
Acting Director of Neuro-Magnetic-Resonance Imaging, Department of Radiology, Neuroradiology Division, The John Hopkins University School of Medicine, Baltimore, MD, 7/1987-6/1988
Co-Director of Neuro-Magnetic-Resonance Imaging, The Johns Hopkins University School of Medicine, Baltimore, MD, 7/1986-6/1987

Institutional Committee Activities

Member, Diagnostic Imaging MRI Safety Committee, 2007-present
Member, Promotion and Tenure Committee, 1997-2000

Honors and Awards

2015 Life Time Service Award, American Board of Radiology
2012 Top Doctors, U.S. News Top Doctors
2006 Teacher of the Year, The University of Texas Health Science Center-Houston
2001 Teacher of the Year, The University of Texas Health Science Center-Houston

Professional Memberships

American Board of Radiology
Neuroradiology Board Examiner, 1999-2014
American Society of Functional Neuroradiology
Member, 2006-present
American Society of Head and Neck Radiology
Member, 1990-present
American Society of Neuroradiology
Member, 1978-present
Radiological Society of North America
Member, 1985-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Shah KB, Hayman LA, Chavali LS, Hamilton JD, Prabhu SS, Wangaryattawanich P, Kumar VA, Kumar AJ. Glial Tumors in Brodmann Area 6: Spread Pattern and Relationships to Motor Areas. Radiographics 35(3):793-803, May-Jun, 5/2015. PMID: 25969935.
2. Pickering CR, Shah K, Ahmed S, Rao A, Frederick MJ, Zhang J, Unruh AK, Wang J, Ginsberg LE, Kumar AJ, Myers JN, Hamilton JD. CT imaging correlates of genomic expression for oral cavity squamous cell carcinoma. AJNR Am J Neuroradiol 34(9):1818-22, 9/2013. e-Pub 6/2013. PMID: 23764725.
3. Kumar VA, Hamilton J, Hayman LA, Kumar AJ, Rao G, Weinberg JS, Sawaya R, Prabhu SS. Deformable Anatomic Templates (DAT) Improve Analysis of Gliomas with Minimal Mass Effect in Eloquent Areas. Neurosurgery 73(3):534-42, 9/2013. e-Pub 5/2013. PMID: 23728447.
4. Hamilton JD, Ahmed S, Sandulache VC, Daram SP, Ow TJ, Skinner HD, Rao A, Ginsberg LE, Kumar AJ, Myers JN. Improving Imaging Diagnosis of Persistent Nodal Metastases after Definitive Therapy for Oropharyngeal Carcinoma: Specific Signs for CT and Best Performance of Combined Criteria. AJNR Am J Neuroradiol 34(8):1637-42, 8/2013. e-Pub 3/2013. PMCID: PMC3939678.
5. Raslan O, Debnam JM, Ketonen L, Kumar AJ, Schellingerhout D, Wang J. Stereoscopic visualization of diffusion tensor imaging data: A comparative survey of visualization techniques. Radiol Res Pract 2013:780916, 2013. e-Pub 10/2013. PMCID: PMC3819952.
6. Hayman LA, Kumar VA, Hamilton J, Prabhu SS, Thiebaut de Schotten M, Al-Zubidi N, Pagani J, Vabulas M, Groneman M, Kumar, AJ. Deformable Anatomic Template Embeds Knowledge into Patients Brain Images: Part 1. Construction and Display. J Comput Assist Tomogr 36(3):354-9, May-Jun, 5/2012. PMID: 22592623.
7. Hamilton JD, Kumar VA, Hayman LA, Prabhu SS, Hou P, Jackson EF, Groneman M, Pagani J, Vabulas M, Kumar, AJ. Deformable anatomic templates embed knowledge into brain images: Part 2. Validation using functional magnetic resonance imaging of the motor hand. J Comput Assist Tomogr 36(2):280-284, Mar-Apr, 3/2012. PMCID: PMC3910394.
8. Shah KB, Guha-Thakurta N, Schellingerhout D, Madewell JE, Kumar, AJ, Costelloe CM. Comparison of gadolinium-enhanced fat-saturated T1-weighted FLAIR and fast spin-echo MRI of the spine at 3 T for evaluation of extradural lesions. AJR Am J Roentgenol 197(3):697-703, 9/2011. PMID: 21862814.
9. Vu TH, Guha-Thakurta N, Harrell RK, Ahmed S, Kumar AJ, Johnson VE, Perrier ND, Hamberg LM, Hunter GJ, Schellingerhout D. Imaging characteristics of hyperfunctioning parathyroid adenomas using multiphase multidectector computed tomography: a quantitative and qualitative approach. J Comput Assist Tomogr 35(5):560-7, Sep-Oct, 9/2011. PMID: 21926850.
10. de Groot JF, Fuller G, Kumar, AJ, Piao Y, Eterovic K, Ji Y, Conrad CA. Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice. Neuro Oncol 12(3):233-42, 3/2010. e-Pub 1/2010. PMCID: PMC2940588.
11. Kumar AJ, Leeds NE, Kumar VA, Fuller GN, Lang FF, Milas Z, Weinberg JS, Ater JL, Sawaya R. Magnetic resonance imaging features of pilocytic astrocytoma of the brain mimicking high-grade gliomas. J Comput Assist Tomogr 34(4):601-611, 2010. PMID: 20657231.
12. Levin VA, Bidaut L, Hou P, Kumar AJ, Wefel JS, Bekele BN, Prabhu S, Loghin M, Gilbert MR, Jackson EF. Randomized double-blind placebo-controlled trial of bevacizumab therapy for radiation necrosis of the central nervous system. Int J Radiat Oncol Biol Phys. e-Pub 2010. PMCID: PMCPMC2908725.
13. Gonzalez J, Kumar AJ, Conrad CA, Levin VA. Effect of bevacizumab on radiation necrosis of the brain. Int J Radiat Oncol Biol Phys 67(2):323-326, 2007. PMID: 17236958.
14. Rozner MA, Burton AW, Kumar AJ. Pacemaker complication during magnetic resonance imaging. J Am Coll Cardiol 45:161-162, 2005. PMID: 15629394.
15. Lisenko Y, Kumar AJ, Yao J, Ajani J, Ho L. Leptomeningeal carcinomatosis originating from gastric cancer: report of eight cases and review of the literature. Am J Clin Oncol 26(2):165-170, 2003. PMID: 12714889.
16. Leeds NE, Kumar AJ, Zhou XJ, McKinnon GC. Magnetic resonance imaging of benign spinal lesions simulating metastasis: role of diffusion-weighted imaging. Top Magn Reson Imaging 11(4):224-234, 2000. PMID: 11133064.
17. Kumar AJ, Leeds NE, Fuller GN, Van Tassel P, Maor MH, Sawaya RE, Levin VA. Malignant gliomas: MR imaging spectrum of radiation therapy- and chemotherapy-induced necrosis of the brain after treatment. Radiology 217(2):377-384, 2000. PMID: 11058631.

Abstracts

1. Vu T, Chasen n, Bezerra R, Chavali L, Kwon M, Ahemd S, Kumar AJ, Perrier N. Atlas-guided 4DCT detection and calssification of parathyroid adenomas. Proceedings Book of the Annual American Society of Neuroradiology 53rd Meeting, 4/2015.
2. Bezerra R, Chavali L, Gogia B, Kumar AJ. Atlas-guided 4DCT detection and classification of parathyroid adenomas. Proceedings Book of the Annual American Society of Neuroradiology 53rd Meeting, 4/2015.
3. Elakkad A, Elbabab M, Kotrotsou A, Hatami M, Kumar V, Kumar AJ, Colen R. Multiparametric advanced MR Imaging (IVIM, DCEMR, 2D and 3D tumor metrics) as a predictive tool of treatment response in HPV positive oropharyngeal squamous cell carcinoma patient. Proceedings Book of the Annual American Society of Neuroradiology 53rd Meeting, 4/2015.
4. Kumar V, Shah K, Chavali L, Schellingerhout D, Kumar AJ, Ganesh R, Prabhu R. Pre-operative planning for intracerebal tumors-a video report of what surgeons need to know. Proceedings Book of the Annual American Society of Neuroradiology 53rd Meeting, 4/2015.
5. Hassan I, Hou P, Li G, Colen R, Kumar AJ, Liu H. Pre-surgical fMRI: A method to assess accuracy of functional localization. Proceedings Book of the Annual American Society of Neuroradiology 53rd Meeting, 4/2015.
6. Vabulas M, Kumar V, Shah KB, Kumar AJ, Prabhu S. Validation of intraoperative real-time atlas-based stereotactic neurosurgery near eloquent motor areas during tumor recession. Proceedings Book of the Annual American Society of Neuroradiology 53rd Meeting, 4/2015.
7. P Wangaryattawanich, Z Mahmood, L Chavali, A Kumar, L Ketonen, L Hayman. Classification of Glial Tumors in the Deep White Matter and Corpus Callosum. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting (#EdE-24), 5/2014.
8. P Wangaryattawanich, J Wang, A Kumar, P Zinn, R Colen. Comprehensive Survival Analysis of Pre-Operative Imaging Features in Patients with Glioblastoma. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting (#O-321), 5/2014.
9. J Hamilton, S Guillory, L Chavali, V Kumar, C Ison, K Shah, D Schellingerhout, S Prabhu, L Chi, R Colen, J Wefel, L Hayman, A Kumar. Insights from the Ventral Premotor Cortex (BA 44): Glial Tumor Spread Pattern Important for Survival and Functional Outcomes. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting (#EP-77), 5/2014.
10. J Hamilton, J Hunter, L Chavali, V Kumar, K Shah, D Schellingerhout, G Fuller, S Guillory, C Ison, C Matuschek, E Boelke, R Colen, L Chi, S Prabhu, L Hayman, A Kumar. Predicting the Spread of Glial Tumors: Insights from “Gliography” of the Cingulate. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting (#eEdE-82c), 5/2014.
11. V Kumar, L Chavali, J Hamilton, F Lang, J Hunter, M Thiebaut de schotten, D O'Donoghue, G Fuller, T Naidich, A Kumar, L Hayman. Predicting the Spread of Glial Tumors: Lessons from the Insular Connections to the Frontal Lobe. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting (#O-59), 5/2014.
12. Shah KB, Hamilton JD, Chavali L, Hayman LA, Wangaryattawanich P, Hunter JV, Colen RR, Schellingerhout D, Prabhu S, Kumar AJ. Imaging Appearance and Spread Pattern of Glial Tumors in the Supplementary Motor Area (Brodmann Area 6). Proceedings book of the 99th annual meeting of Radiological Society of North America (#LL – NRE3141), 12/2013.
13. Hamilton JD, Hunter JV, Chavali L, Kumar VA, Ison C, Prabhu S, Shah KB, Matuschek C, Boelke E, Colen RR, Chi TL, Schellingerhout D, Fuller GN, Hayman LA, Kumar AJ. Predicting the Spread of Glial Tumors: Insights from the Posterior and Restrosplenial Cingulate (BA 23, 31, 26, 29, and 30). Proceedings book of the 99th annual meeting of Radiological Society of North America:372 (#LL-NRE3139-WEB), 12/2013.
14. Kumar VA, Hamilton JD, Hunter JV, Lang FF, Chavali L, Fuller GN, Colen RR, Kumar AJ, Hayman LA. Predicting the Spread of Glial Tumors: Lessons from the Insular Cortex. Proceedings book of the 99th annual meeting of Radiological Society of North America:375 (#LL-NRE3140), 12/2013.
15. Colen RR, Chavali L, Kumar VA, Hamilton JD, Lang FF, Fuller GN, Ison C, Shah KB, Ketonen LM, Kumar AJ, Hayman LA. Predicting the Spread of Glial Tumors: Lessons from the Subcentral Gyrus (Brodmann Area 43). Proceedings book of the 99th annual meeting of Radiological Society of North America:387 (#LL-NRE4592), 12/2013.
16. Colen RR, Sathyan P, Kumar AJ, Zinn PO. Validating MRI as a Screening Tool for Genomic Target Discovery for Therapeutic Drug Development. Proceedings book of the 99th annual meeting of Radiological Society of North America:153 (#SSC11-07), 12/2013.
17. Ison C, Kumar AJ, Ketonen L, Schellingerhout D, Jackson EF, Hou P, Hamilton JD. Assessment of nonenhancing T2 signal abnormalities before or after treatment of brain tumors: Myoinositol and apparant diffusion coefficient values may be more helpful than choline ratios and perfusion imaging. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting, 5/2013.
18. Hamilton JD, Kumar VA, Schellingerhout D, Shah K, Chi L, Hunter J, Naidich TP, Chavalli L, Leeds NE, Prabhu S, Kumar AJ, Hayman LA. Elemental brain volumes derived from cytoarchitectonics and crossing white matter tracts are an independent predictor mortality for glioma with improved understanding of infiltration. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting, 5/2013.
19. Ahmed S, Jones J, Steele J, Sandulache VC, Ow TJ, Skinner HD, Rao A, Ginsberg LE, Kumar AJ, Myers JN, Hamilton JD. Estimates of clinical cost savings for new, better performing criteria for diagnosis of persistent nodal metastases after treatment for oropharyngeal carcinoma. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting, 5/2013.
20. Hunter JV, Hamilton J, Hayman L, O'Donoghue D, Pagani J, Kumar V, Kumar AJ, Naidich TP. Glial Tumors: Lessons from the anterior cingulate cortex. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting, 5/2013.
21. Hamilton JD, Hayman LA, Kumar V, Schellingerhout D, Shah K, Chi L, Hunter J, Chavalli L, Leeds NE, Prabhu S, Kumar AJ, Naidich TP. On the shoulders of giants: "Elemental brain volumes" derived from modifications of prior parcellation strategies help to explain glial tumor spread. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting, 5/2013.
22. Hamilton JD, Jackson EF, Leeds NE, Ketonen L, Schellingerhout D, Jones J, Tatum LS, Hou P, Evans DT, Underwood ML, Jones JR, Reed BJ, Hash S, Steele J, Albright HW, Kumar AJ. redicting recurrent glioma versus treatment related necrosis using multiparameter advanced MR imaging: Accurate and cost effective clinical decision making. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting, 5/2013.
23. Hamilton JD, Kumar VA, Prabhu SS, Shah K, Peiffer A, Hayman LA, <b>Kumar AJ</b>. Anatomic Considerations for Somatotopic Organization of the Descending Motor Fibers: A Pictorial Essay. Interaoperative Imaging Society, St. Louis Missouri, 2013, 2013.
24. Kumar VA, Hamilton J, Hayman LA,Kumar AJ, Rao G, Weinberg JS, Sawaya R, Prabhu SS. Deformable Anatomic Templates Improve Analysis of Eloquent Area Gliomas with Minimal Mass Effect. Intraoperative Imaging Society, St. Louis, Missouri 2013, 2013.
25. Hamilton JD, Kumar V, Schellingerhout D, Shah K, Chi L, Hunter J, Naidich TP, Chavali L, Leeds NE, Prabhu S, Kumar AJ, Hayman LA. Revisiting the Architecture of the Cerebral Hemispheric White Matter: a New Parcellation Strategy Reveals That Invasion of the Deep White Matter Is an Independent Predictor of Mortality for Glioma Patients. American Association of Neurosurgery - Tumor Section, 2013.

Last updated: 7/1/2015