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Beverly (Ashleigh) A. Guadagnolo, M.D., M.P.H.

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Associate Professor, Department of Health Services Research, Division of OVP, Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

2005 Harvard School of Public Health, Boston, MA, MPH, Public Health
2001 Harvard Medical School, Boston, MA, MD, Medicine
1996 University of Texas at Austin, Austin, TX, BA, Biology

Postgraduate Training

2004-2005 Research Fellowship, National Cancer Institutes Fellowship in Cancer Prevention, Harvard School of Public Health, Boston, MA
7/2002-6/2006 Residency and Chief Residency, Harvard Joint Center for Radiation Therapy, Boston, MA
7/2001-6/2002 Clinical Internship, Newton Wellesley Hospital, Newton, MA

Experience/Service

Other Appointments/Responsibilities

Member, Technical Expert Panel, Agency for Health Care Research and Quality (AHRQ), Project on Radiotherapy Treatments for Head and Neck Cancer Update, Chicago, IL, 4/2013-present
Member, Advisory Committee on Minority Health, United States Health and Human Services, Washington, DC, 11/2012-11/2016
Member, Quality Indicators ICD10-CM/PCS Conversion Workgroup, Agency for Health Care Research and Quality (AHRQ), Sacramento, CA, 8/2012-10/2012
Co-Director/Co-Coordinator, Four Directions Summer Research Program, Harvard Medical School, Boston, MA, 1997-2005

Institutional Committee Activities

Associate member, IRB 4, 9/2009-present
Member, Psychosocial, Behavioral, Health Services Research Committee, 9/2006-8/2009
Member, Residency Selection Committee, Harvard Joint Center for Radiation Therapy, 2002-2006

Professional Memberships

Academy Health
Member, 5/2008-present
American Society for Therapeutic Radiology and Oncology (ASTRO)
Member, 9/2006-present
American Society of Clinical Oncology
Member, 1/2007-present
Connective Tissue Oncology Society (CTOS)
Member, 7/2008-present
Massachusetts Medical Society, MA
Member, 9/1997-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Huo J, Lairson DR, Du XL, Chan W, Jiang J, Buchholz TA, Guadagnolo BA. Hospital Case Volume is Associated with Improved Survival for Patients with Metastatic Melanoma. Am J Clin Oncol. e-Pub 4/2014. PMID: 24755661.
2. Guadagnolo BA, Liao KP, Giordano SH, Elting LS, Buchholz TA, Shih YC. Increasing Use of Advanced Radiation Therapy Technologies in the Last 30 Days of Life Among Patients Dying As a Result of Cancer in the United States. J Oncol Pract. e-Pub 4/2014. PMID: 24756144.
3. Beadle BM, Liao KP, Elting LS, Buchholz TA, Ang KK, Garden AS, Guadagnolo BA. Improved survival using intensity-modulated radiation therapy in head and neck cancers: A SEER-Medicare analysis. Cancer 120(5):702-710, 3/2014. e-Pub 1/2014. PMID: 24421077.
4. Beadle BM, Liao KP, Chambers MS, Elting LS, Buchholz TA, Kian Ang K, Garden AS, Guadagnolo BA. Evaluating the Impact of Patient, Tumor, and Treatment Characteristics on the Development of Jaw Complications in Patients Treated for Oral Cancers: A SEER-Medicare Analysis. Head Neck 35(11):1599-1605, 11/2013. e-Pub 11/2012. PMID: 23150453.
5. Guadagnolo BA, Prieto V, Weber R, Ross MI, Zagars GK. The role of adjuvant radiotherapy in the local management of desmoplastic melanoma. Cancer. e-Pub 10/2013. PMID: 24142803.
6. Castle KO, Guadagnolo BA, Tsai CJ, Feig BW, Zagars GK. Dermatofibrosarcoma Protuberans: Long-term Outcomes of 53 Patients Treated With Conservative Surgery and Radiation Therapy. Int J Radiat Oncol Biol Phys 86(3):585-590, 7/2013. e-Pub 4/2013. PMID: 23628134.
7. Chao AH, Sturgis EM, Yu P, Skoracki RJ, Guadagnolo BA, Hanasono MM. Reconstructive outcomes in patients with head and neck sarcoma. Head Neck 35(5):677-683, 5/2013. e-Pub 6/2012. PMID: 22711660.
8. Huo J, Du XL, Lairson DR, Chan W, Jiang J, Buchholz TA, Guadagnolo BA. Utilization of Surgery, Chemotherapy, Radiation Therapy, and Hospice at the End of Life for Patients Diagnosed with Metastatic Melanoma. Am J Clin Oncol. e-Pub 5/2013. PMCID: PMC3796177.
9. Torres KE, Ravi V, Kin K, Yi M, Guadagnolo BA, May CD, Arun BK, Hunt KK, Lam R, Lahat G, Hoffman A, Cormier JN, Feig BW, Lazar AJ, Lev D, Pollock RE. Long-Term Outcomes in Patients with Radiation-Associated Angiosarcomas of the Breast Following Surgery and Radiotherapy for Breast Cancer. Ann Surg Oncol 20(4):1267-1274, 4/2013. e-Pub 12/2012. PMID: 23224828.
10. Lee JM, Mehta UN, Dsouza LH, Guadagnolo BA, Sanders DL, Kim KB. Long-term stabilization of leptomeningeal disease with whole-brain radiation therapy in a patient with metastatic melanoma treated with vemurafenib: a case report. Melanoma Res 23(2):175-178, 4/2013. e-Pub 1/2013. PMID: 23358426.
11. Guadagnolo BA, Huo J, Liao KP, Buchholz TA, Das P. Changing trends in radiation therapy technologies in the last year of life for patients diagnosed with metastatic cancer in the United States. Cancer 119(5):1089-1097, 3/2013. e-Pub 11/2012. PMCID: PMC3688625.
12. Guadagnolo BA, Liao KP, Elting L, Giordano S, Buchholz TA, Shih YC. Use of Radiation Therapy in the Last 30 Days of Life Among a Large Population-Based Cohort of Elderly Patients in the United States. J Clin Oncol 31(1):80-87, 1/2013. e-Pub 11/2012. PMCID: PMC3530693.
13. Wang WL, Katz D, Araujo DM, Ravi V, Ludwig JA, Trent JC, Patel SR, Lin PP, Guadagnolo BA, Lòpez-Terrada D, Dei Tos AP, Lewis VO, Lev D, Pollock RE, Zagars GK, Benjamin RS, Madewell JE, Lazar AJ. Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy. Clin Sarcoma Res 2(1). e-Pub 12/2012. PMID: 23272660.
14. Guadagnolo BA, Xu Y, Zagars GK, Cormier JN, Pollock RE, Feig BW, Giordano S, Buchholz TA, Shih YC. A population-based study of the quality of care in the diagnosis of large (≥ 5 cm) soft tissue sarcomas. Am J Clin Oncol 35(5):455-461, 10/2012. e-Pub 4/2011. PMID: 21537147.
15. Nasser QJ, Gombos DS, Williams MD, Guadagnolo BA, Morrison WH, Garden AS, Beadle BM, Canseco E, Esmaeli B. Management of radiation-induced severe anophthalmic socket contracture in patients with uveal melanoma. Ophthal Plast Reconstr Surg 28(3):208-212, May-Jun, 5/2012. PMCID: PMC3359825.
16. Guadagnolo BA, Cina K, Koop D, Brunette D, Petereit DG. A pre-post survey analysis of satisfaction with health care and medical mistrust after patient navigation for American Indian cancer patients. J Health Care Poor Underserved 22(4):1331-1343, 11/2011. PMCID: PMC3676310.
17. Kelly P, Zagars GK, Cormier JN, Ross MI, Guadagnolo BA. Sphincter-sparing local excision and hypofractionated radiation therapy for anorectal melanoma: A 20-year experience. Cancer 117(20):4747-4755, 10/2011. e-Pub 3/2011. PMID: 21446049.
18. Subrahmanian K, Petereit DG, Kanekar S, Burhansstipanov L, Esmond S, Miner R, Spotted Tail C, Guadagnolo BA. Community-based participatory development, implementation, and evaluation of a cancer screening educational intervention among American Indians in the Northern Plains. J Cancer Educ 26(3):530-539, 9/2011. e-Pub 3/2011. PMCID: PMC3162121.
19. Shinder R, Jackson TL, Araujo D, Prieto VG, Guadagnolo BA, Esmaeli B. Preoperative radiation therapy in the management of recurrent orbital hemangiopericytoma. Ophthal Plast Reconstr Surg 27(5):e126-128, Sep-Oct, 9/2011. PMID: 21242853.
20. Guadagnolo BA, Boylan A, Sargent M, Koop D, Brunette D, Kanekar S, Shortbull V, Molloy K, Petereit DG. Patient navigation for American Indians undergoing cancer treatment: utilization and impact on care delivery in a regional health care center. Cancer 117(12):2754-2761, 6/2011. e-Pub 12/2010. PMCID: PMC3112306.
21. Huh WW, Guadagnolo BA, Munsell MF, Patel S, Lewis VO. Soft tissue sarcomas of the popliteal fossa: a single-institution retrospective review. Cancer 117(12):2728-2734, 6/2011. e-Pub 12/2010. PMID: 21656751.
22. Guadagnolo BA, Zagars GK, Araujo D, Ravi V, Shellenberger TD, Sturgis EM. Outcomes after definitive treatment for cutaneous angiosarcoma of the face and scalp. Head Neck 33(5):661-667, 5/2011. e-Pub 10/2010. PMID: 20960566.
23. Liu CC, Xia R, Guadagnolo BA, Cormier JN, Du XL. Risk of Xerostomia in Association with the Receipt of Radiation Therapy in Older Patients with Head and Neck Cancer. Am J Ther 18(3):206-215, 5/2011. e-Pub 1/2010. PMID: 20068441.
24. Clark DW, Moore BA, Patel SR, Guadagnolo BA, Roberts DB, Sturgis EM. Malignant fibrous histiocytoma of the head and neck region. Head Neck 33(3):303-308, 3/2011. e-Pub 7/2010. PMID: 20629084.
25. Pandhi N, Guadagnolo BA, Kanekar S, Petereit DG, Karki C, Smith MA. Intention to receive cancer screening in Native Americans from the Northern Plains. Cancer Causes Control 22(2):199-206, 2/2011. e-Pub 12/2010. PMCID: PMC3042877.
26. Guadagnolo BA, Liu CC, Cormier JN, Du XL. Evaluation of trends in the use of intensity-modulated radiotherapy for head and neck cancer from 2000 through 2005: socioeconomic disparity and geographic variation in a large population-based cohort. Cancer 116(14):3505-3512, 7/2010. PMID: 20564123.
27. Guadagnolo BA, Myers JN, Zagars GK. Role of postoperative irradiation for patients with bilateral cervical nodal metastases from cutaneous melanoma: a critical assessment. Head Neck 32(6):708-713, 6/2010. PMID: 19787786.
28. Pandhi N, Guadagnolo BA, Kanekar S, Petereit DG, Smith MA. Cancer screening in Native Americans from the Northern Plains. Am J Prev Med 38(4):389-395, 4/2010. PMCID: PMC2851544.
29. Guadagnolo BA, Petereit DG, Helbig P, Koop D, Kussman P, Fox Dunn E, Patnaik A. Involving American Indians and medically underserved rural populations in cancer clinical trials. Clin Trials 6(6):610-617, 12/2009. e-Pub 11/2009. PMCID: PMC2891042.
30. Agrawal S, Kane JM, Guadagnolo BA, Kraybill WG, Ballo MT. The benefits of adjuvant radiation therapy following therapeutic lymphadenectomy for clinically advanced, high risk nodal metastatic melanoma. Cancer 115(24):5836-5844, 12/2009. e-Pub 8/2009. PMID: 19701906.
31. Guadagnolo BA, Zagars GK, Raymond AK, Benjamin RS, Sturgis EM. Osteosarcoma of the jaw/craniofacial region: outcomes after multimodality treatment. Cancer 115(14):3262-3270, 7/2009. PMID: 19382187.
32. Raphael JL, Guadagnolo BA, Beal AC, Giardino AP. Racial and ethnic disparities in indicators of a primary care medical home for children. Acad Pediatr 9(4):221-227, Jul-Aug, 7/2009. e-Pub 5/2009. PMID: 19487171.
33. Beadle BM, Guadagnolo BA, Ballo MT, Lee JE, Gershenwald JE, Cormier JN, Mansfield PF, Ross MI, Zagars GK. Radiation therapy field extent for adjuvant treatment of axillary metastases from malignant melanoma. Int J Radiat Oncol Biol Phys 75(5):1376-1382, 4/2009. e-Pub 9/2008. PMID: 18774657.
34. Guadagnolo BA, Cina K, Helbig P, Reiner M, Molloy K, Petereit DG. Medical mistrust and less satisfaction with health care among Native Americans presenting for cancer treatment. Journal of Health Care for the Poor and Underserved 20(1):210-226, 2/2009. PMID: 19202258.
35. Guadagnolo BA, Cina K, Helbig P, Molloy K, Reiner M, Cook EF, Petereit DG. Assessing cancer stage and screening disparities among Native American cancer patients. Public Health Rep 124(1):79-89, Jan-Feb, 1/2009. PMCID: PMC2602933.
36. Guadagnolo BA, Zagars GK, Ballo MT, Strom SS, Pollock RE, Benjamin RS. Mortality after cure of soft-tissue sarcoma treated with conservation surgery and radiotherapy. Cancer 113(2):411-418, 7/2008. PMID: 18506733.
37. Guadagnolo BA, Zagars GK, Ballo MT. Long-term outcomes for desmoid tumors treated with radiation therapy. International Journal of Radiation Oncology Biology and Physics 71(2):441-447, 6/2008. e-Pub 12/2007. PMID: 18068311.
38. Guadagnolo BA, Zagars GK, Ballo MT, Patel SR, Lewis VO, Benjamin RS, Pollock RE. Excellent local control rates and distinctive patterns of failure in myxoid liposarcoma treated with conservation surgery and radiotherapy. Int J Radiat Oncol Biol Phys 70(3):760-765, 3/2008. e-Pub 9/2007. PMID: 17892916.
39. Guadagnolo BA, Zagars GK, Ballo MT, Patel SR, Lewis VO, Pisters PW, Benjamin RS, Pollock RE. Long-term outcomes for synovial sarcoma treated with conservation surgery and radiotherapy. Int J Radiat Oncol Biol Phys 69(4):1173-1180, 11/2007. e-Pub 8/2007. PMID: 17689031.
40. Guadagnolo BA, Punglia RS, Kuntz KM, Mauch PM, Ng AK. Cost-effectiveness analysis of computerized tomography in the routine follow-up of patients after primary treatment for Hodgkin's disease. J Clin Oncol 24(25):4116-4122, 9/2006. PMID: 16943528.
41. Guadagnolo BA, Li S, Neuberg D, Ng A, Hua L, Silver B, Stevenson MA, Mauch P. Long-term outcome and mortality trends in early-stage, Grade 1-2 follicular lymphoma treated with radiation therapy. Int J Radiat Oncol Biol Phys 64(3):928-934, 3/2006. e-Pub 10/2005. PMID: 16243446.
42. Guadagnolo BA, Haddad RI, Posner MR, Weeks L, Wirth LJ, Norris CM, Sullivan CA, Goguen L, Busse PM, Tishler R. Organ preservation and treatment toxicity with induction chemotherapy followed by radiation therapy or chemoradiation for advanced laryngeal cancer. Am J Clin Oncol 28(4):371-8, 8/2005. PMID: 16062079.

Invited Articles

1. Guadagnolo BA, Dohan D, Raich P. Metrics for evaluating patient navigation during cancer diagnosis and treatment: crafting a policy-relevant research agenda for patient navigation in cancer care. Cancer 117(15 (Suppl)):3565-3574, 8/2011. PMID: 21780091.
2. Petereit DG, Guadagnolo BA, Wong R, Coleman CN. Addressing Cancer Disparities Among American Indians Through Innovative Technologies and Patient Navigation: The Walking Forward Experience. Front Oncol 1:11, 2011. e-Pub 6/2011. PMCID: PMC3355933.
3. Reynoso D, Subbiah V, Trent JC, Guadagnolo BA, Lazar AJ, Benjamin R, Pollock RE, Ludwig JA. Neoadjuvant treatment of soft tissue sarcoma: A multimodality approach. J Surg Oncol 101(4):327-333, 3/2010. PMID: 20187067.
4. Guadagnolo BA, Zagars GK. Adjuvant radiation therapy for high-risk nodal metastases from cutaneous melanoma. Lancet Oncol 10(4):409-416, 4/2009. PMID: 19341972.
5. Guadagnolo BA, Mamon H. Adverse effects of preoperative radiation therapy in rectal cancer. American Journal of Oncology Review 5(3 (Suppl 2)):26-28, 2005.

Abstracts

1. Beadle BM, Liao K, Chambers MS, Elting LS, Buchholz TA, Ang KK, Garden AS, Guadagnolo BA. The Impact Of Treatment And Tumor Characteristics In The Development Of Osteoradionecrosis In Patients Treated For Oral Cancers: A SEER-Medicare Analysis. ASTRO Multidisciplinary Head and Neck Cancer Symposium--Oral Presentation, 1/2012.
2. Ballas LK, Pan I, Guadagnolo BA, Smith BD, Buchholz TA, Dabaja BS. Trends in utilization of intensity-modulated radiotherapy in diffuse large B-cell lymphoma in the U.S. from 2001 to 2005: a population-based study. ASTRO Annual Meeting 2011-Poster presentation, 10/2011.
3. Huh WW, Guadagnolo BA, Munsell MF, Patel S, Lewis VO. Soft tissue sarcoma of the popliteal fossa. CTOS 16th Annual Meeting, Paris, France, 11/2010.
4. Kelly P, Guadagnolo BA, Cormier JN, Ross MI, Zagars GK. Sphincter sparing local excision and hypofractionated radiation therapy for anal-rectal melanoma: a 20-year experience. International Journal of Radiation Oncology Biology Physics 78(3 (Suppl)):S611 (Abstract #2911), 10/2010.
5. Guadagnolo BA, Boylan A, Sargent M, Koop D, Brunette D, Kanekar S, Shortbull V, Molloy K, Petereit DG. Patient navigation utilization among American Indian cancer patients in the Northern Plains. Academy Health Annual Research Meeting, June 26-30,2010, Boston, MA, 7/2010.
6. Petereit DG, Moser A, Molloy K, Roberts C, Guadagnolo BA, Burhansstipanov L, Coleman NC. Walking Forward: A community based research program addressing high cancer mortality rates in the American Indian population of western South Dakota. Fourth International Conference on Translational Research and Pre-Clinical Strategies in Radiation Oncology (Invited oral presentation by Dr. Petereit), March 11-13, 2009, 3/2009.
7. Petereit D, Burhansstipanov L, Guadagnolo BA, Helbig P, and others. Walking Forward: NIH disparities project to lower cancer mortality rates for American Indians in Western South Dakota. NCI Translational Research Meeting, Washington, D.C. November 7-9, 2008, 11/2008.
8. Beadle BM, Guadagnolo BA, Ballo MT, Lee J, Gershenwald J, Cormier J, Ross M, Zagars GK. Radiation therapy field extent for adjuvant treatment of axillary metastases from malignant melanoma. American Society for Therapeutic Radiology and Oncology 50th Annual Meeting, Sept. 20-25, 2008, Boston, MA (Oral presentation, Dr. Beadle), 9/2008. e-Pub 9/2008. PMID: 18774657.
9. Molloy K, Guadagnolo BA, Cina K, Helbig P, Reiner M, Petereit D. Trust and Satisfaction in a Northern Plains Native American Cancer Population: Walking Forward Program. Cancer Health Disparities Summit 2008, Bethesda, MD, July 14- 16, 2008, 7/2008.
10. Agrawal S, Kane J, Guadagnolo BA, Kraybill W, Ballo MT. Therapeutic lymphadenectomy alone versus adjuvant radiotherapy for regional nodal metastases from melanoma. 44th Annual Meeting of the American Society of Clinical Oncology, 5/2008.
11. Raphael JL, Guadagnolo BA, Beal AC, Giardino AP. Racial and ethnic disparities in access to a medical home: secondary analysis of the National Survey of Children's Health. Proceedings of the 2008 Pediatric Academic Societies' Annual Meeting (#750947), 2008.
12. Guadagnolo BA, Punglia R, Kuntz K, Mauch P, Ng A. Cost-effectiveness of computerized tomography in follow-up of patients with complete response after primary treatment for Hodgkin's Disease. Int J Radiat Oncol Biol Phys 63(2) Suppl 1:S114, 2005.
13. Guadagnolo BA, Tishler R, Posner M, Weeks L, Wirth L, Norris C, Sullivan C, Goguen L, Busse P, Haddad R. Organ preservation for patients treated with induction chemotherapy (IC) followed by radiation therapy (RT) or chemoradiation (CRT) for advanced stage squamous cell carcinoma of the larynx (SCCL). (publication only). Proceedings of the 2004 Meeting of the American Society of Clinical Oncology 22(14S):5600, 2004.
14. Guadagnolo BA, Li S, Neuberg D, Ng A, Hua L, Silver B, Stevenson M, Mauch P. Long-term outcome and mortality trends in follicular lymphoma treated with radiation therapy (poster presentation). Proceedings of the European Cancer Conference (ECCO 12), Euro J Cancer 1(Suppl5):S306, 2003.

Grant & Contract Support

Title: Using Claims Data to Evaluate Radiation Therapy Utilization at the End of Life
Funding Source: NIH/NCI
Role: Principal Investigator
Duration: 9/6/2012 - 8/31/2014

Last updated: 7/14/2014