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Bita Esmaeli, MD, FACS

Present Title & Affiliation

Primary Appointment

Professor of Ophthalmology, Department of Plastic Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Program Director, Ophthalmic Plastic & Reconstructive Surgery Fellowship, Department of Plastic Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Adjunct Professor of Ophthalmology, Department of Ophthalmology and Visual Sciences, The University of Texas Medical Branch, Galveston, TX

Bio Statement

 

 

 

Dr Bita Esmaeli is a Professor of Ophthalmology in the Department of Plastic Surgery at The University of Texas M. D. Anderson Cancer Center, where she has an orbital oncology and oncologic oculoplastic surgery practice since 1998.

Dr Esmaeli’s practice focus is surgical treatment of orbital tumors, lacrimal gland carcinomas, eyelid cancers, melanoma of eyelid and conjunctiva, and reconstructive surgery in the periocular region including lacrimal surgery.

Dr Esmaeli has authored over 150 peer-reviewed manuscripts, over 55 invited articles and book chapters, has spearheaded several clinical trials, and has participated in numerous research protocols at M. D. Anderson Cancer Center. She has received many prestigious awards and honors including the Merrill Reeh Pathology Award and the Research Award from the American Society of Ophthalmic Plastic and Reconstructive Surgery, the American Academy of Ophthalmology Senior Achievement Award, Best Doctors in America, and Top Doctors Award. Dr Esmaeli was inducted as a member of the prestigious American Ophthalmologic Society in 2012.

Dr Esmaeli 's research interests include molecular signature of ocular and orbital tumors, tissue banking for rare tumors of the eye and orbit, eye and vision-sparing treatment strategies for orbital and ocular cancers, and ocular and orbital side effects of cancer therapy.

Dr. Esmaeli was instrumental in establishing the Ophthalmology Section as a comprehensive full-time service at M. D. Anderson Cancer Center in 1998. She served as the Director of the Ophthalmologic Services from 1998 to 2001 and as the Chief of the Ophthalmology Section at M. D. Anderson from 2001 to 2004. She is the Program Director for an ASOPRS-sponsored and ACGME-approved fellowship in oculoplastic surgery and orbital oncology at M. D. Anderson Cancer Center.

Research Interests

 

1.     Sentinel lymph node biopsy for eyelid and conjunctival tumors (melanoma, sebaceous carcinoma, Merkel cell ca) to detect early metastasis

2.     Immunotherapy for orbital and adnexal lymphomas and lymphoproliferative disorders of the orbit

3.     Use of adjuvant radiation therapy for eyelid and orbital cancers after globe sparing surgery

4.     Management of canalicular stenosis and nasolacrimal duct blockage associated with chemotherapy

5.     Conditional knock-out mouse model of eyelid/conjunctival squamous cell carcinoma as a model for human skin squamous cell carcinoma

6.     Tissue and Blood banking for uveal melanoma and mutational analysis of uveal melanomas as basis for targeted adjuvant treatments in uveal melanoma patients

7.     Implementation of AJCC classification in ophthalmic oncology

Office Address

The University of Texas MD Anderson Cancer Center
Ophthalmic Plastic Surgery Program, Department of Plastic Surgery
1515 Holcombe Boulevard
Unit Number: 1488
Houston, TX 77030
Room Number: FCT19.5003
Email: besmaeli@mdanderson.org

Education & Training

Degree-Granting Education

1986 Chicago Medical School, Chicago, IL, MD, Medicine
1986 University of California, Santa Barbara, CA, MS, Cell Biology and Physiology
1980 Rhodes College, Memphis, TN, BA, Biology

Postgraduate Training

1995-1996 The American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) Fellowship in Ophthalmic Plastic and Reconstructive Surgery, University of Toronto, Toronto, Ontario, Canada
1991-1994 Ophthalmology Residency, University of Michigan, Ann Arbor, MI

Board Certifications

2005 American Board of Ophthalmology
1996 Subspecialty Training (not board certification): American Society of Ophthalmic Plastic & Reconstructive Surgery

Experience/Service

Administrative Appointments/Responsibilities

Vice Chair, Graduate Medical Education, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013-present

Institutional Committee Activities

Chair, Clinical Research Committee, 2004-2007
Vice-chair Elect, Graduate Medical Education Executive Committee, 2001-present

Honors and Awards

2013 2013 Mentorship Award, WIO/AMA Women Physicians Sector
2011 The American Academy of Ophthalmology Senior Achievement Award
2009-present Best Doctors in America, Best Doctors, Inc.
1998 The Research Award, The American Society of Ophthalmic Plastic & Reconstructive Surgery
1997 The Merril Reeh Pathology Award, The American Society of Ophthalmic Plastic & Reconstructive Surgery
1992 The James M. LaBerge Resident Research Award, Department of Ophthalmology, University of Michigan
1989 Alpha Omega Alpha Medical Honor Society Award

Professional Memberships

American Ophthalmologic Society
Member, 2012-present
The American Academy of Ophthalmology
Member, 1991-present
The American College of Surgeons
Member, 2000-present
The American Medical Association
Member, 1998-present
The American Society of Clinical Oncology
Member, 2001-present
The American Society of Ophthalmic Plastic & Reconstructive Surgery
Member, 1997-present
The Association for Research in Vision and Ophthalmology
Member, 1989-present

Selected Publications

Peer-Reviewed Original Research Articles

1. El-Sawy T, Sabichi AL, Myers JN, Kies MS, William WN, Glisson BS, Lippman S, Esmaeli B. Epidermal growth factor receptor inhibitors for treatment of orbital squamous cell carcinoma. Arch Ophthalmol 130(12):1608-11, 12/1/2012. PMID: 23229707.
2. Esmaeli B, Roberts D, Ross M, Fellman M, Cruz H, Kim SK, Prieto VG. Histologic features of conjunctival melanoma predictive of metastasis and death (an American Ophthalmological thesis). Trans Am Ophthalmol Soc 110:64-73, 12/2012. PMCID: PMC3671367.
3. Esmaeli B, Nasser QJ, Cruz H, Fellman M, Warneke CL, Ivan D. American Joint Committee on Cancer T Category for Eyelid Sebaceous Carcinoma Correlates with Nodal Metastasis and Survival. Ophthalmology 119(5):1078-82, 5/2012. e-Pub 2/2012. PMID: 22330966.
4. El-Sawy T, Ali R, Nasser QJ, Esmaeli B. Outcomes of Dacryocystorhinostomy in Patients with Head and Neck Cancer Treated with High-dose Radiation Therapy. Ophthal Plast Reconstr Surg 28(3):196-8, May-Jun, 5/2012. PMID: 22460683.
5. Williams M D, Al-Zubidi N, Debnam J M, Shinder R, DeMonte F, Esmaeli B. Bone Invasion by Adenoid Cystic Carcinoma of the Lacrimal Gland: Preoperative Imaging Assessment and Surgical Considerations. Ophthal Plast Reconstr Surg 26(6):403-8, 2010. PMID: 20924298.
6. Ahmad SM, Esmaeli, B, Williams M, Nguyen J, Fay A, Woog J, Selvadurai D, Rootman J, Weis E, Selva D, McNab A, DeAngelis D, Calle A, Lopez A. American Joint Committee on Cancer classification predicts outcome of patients with lacrimal-gland adenoid cystic carcinoma. Ophthalmology, 116(6):1210-5, 2009. PMID: 19395039.
7. Esmaeli B, McLaughlin P, Pro B, Samaniego F, Gayed I, Hagemeister F, Romaguerra J, Cabanillas F, Neelapu SS, Banay R, Fayad L, Saville MW, Kwak LW. Prospective Trial of Targeted Radioimmunotherapy with Y-90 Ibritumomab Tiuxetan (Zevalin) for Front-line Treatment of Early-stage Extranodal Indolent Ocular Adnexal Lymphoma. Annals of Oncology 20(4):709-14, 2009. PMID: 19150940.
8. Savar A, Ross MI, Prieto VG, Ivan D, Kim SK, Esmaeli B. Sentinel Lymph Node Biopsy for Ocular Adnexal Melanoma: Experience in 30 Patients. Ophthalmology 116(11):2217-23, 2009. PMID: 19766318.
9. Hsu A, Frank S, Ballo MT, Garden AS, Morrison WH, Rosenthal DI, Hatef E, Esmaeli B. Post-operative Adjuvant External-beam Radiation Therapy for Cancers of the Eyelid and Conjunctiva. Ophthal Plast Reconstr Surg 24(6):444-9, 2008. PMID: 19033839.
10. Esmaeli B, Amin S, Valero V, Adinin R, Arbuckle R, Banay R, Do K, Rivera E. Prospective study of incidence and severity of Epiphora and canalicular stenosis in patients with metastatic breast cancer receiving Docetaxel. J Clin Onc 24:3619-22, 2006. PMID: 16877729.

Book Chapters

1. Yin VT, Esmaeli B. Sentinel Lymph Node Assessment and biopsy for Eyelid and Conjunctival Malignancies. In: Clinical Ophthalmic Oncology - Eyelid and Conjunctival Tumours, 2nd. Ed(s) Pe'er J, Singh AD. Springer, 111-124, 2014.
2. Esmaeli B. Sinonasal Cancer:Orbital Exenteration. In: Master Trechniques in Otolaryngologic Surgery - Head and Neck Surgery. 1. Ed(s) Myers EN, Ferris RL. SPI Global, 177-190, 2014.
3. Droll L, Savar A, Esmaeli B. Eyelid and Conjunctival Neoplasms. In: Smith and Nesi's Ophthalmic Plastic and Reconstructive Surgery, Third. Ed(s) Black EH, Nesi FA, Calvano CJ, Gladstone GJ, Levine MR. Springer: New York, 535-550, 2012. ISBN: 978-1-4614-0970-0.
4. Shinder R, Esmaeli B. Eyelid and Ocular Adnexal Reconstruction. In: Smith and Nesi's Ophthalmic Plastic and Reconstructive Surgery, Third. Ed(s) Black EH, Nesi FA, Calvano CJ, Gladstone GJ, Levine MR. Springer: New York, 551-569, 2012. ISBN: 978-1-4614-0970-0.
5. Gayre GS, Soon S, Zelac D, Esmaeli B, Mannor G. Management of Periocular Skin Cancer. In: Clinical Atlas of Procedures in Ophthalmic Surgery. Ed(s) Albert DM/Lucarelli MJ. Oxford University Press, 830-844, 2012.
6. Connor MA, Esmaeli B. Oculoplastic Complications of Cancer Therapy. In: Smith and Nesi's Ophthalmic Plastic and Reconstructive Surgery, Third. Ed(s) Black EH, Nesi FA, Calvano CJ, Gladstone GJ, Levine MR. Springer: New York, 595-605, 2012. ISBN: 978-1-4614-1970-0.
7. Hsu, A, Esmaeli B. Orbital Exenteration. In: American Academy of Ophthalmology Monographs, Surgery of the Eyelid, Orbit, and Lacrimal System. In: Surgery of the Eyelids, Lacrimal System, and Orbit. 8, Second. Ed(s) Michael T. Yen. Oxford University Press, Inc. Oxford New York, 337-348, 2012.
8. Savar A, Esmaeli B. Sentinel Lymph Node Biopsy for Conjunctival and Eyelid Tumors. In: Smith and Nesi's Ophthalmic Plastic and Reconstructive Surgery, Third. Ed(s) Black EH, Nesi FA, Calvano CJ, Gladstone GJ, Levine MR. Springer: New York, 589-594, 2012. ISBN: 978-1-4614-0970-0.
9. Hayek B, Esmaeli B. Lacrimal Gland Tumors. In: Duane's Clinical Ophthalmology. Vol. 2, Chapter 47. Lippincott, Williams and Wilkins: Philadelphia, Pennsylvania, 2010.
10. Esmaeli B. Pigmented Eyelid Lesions. In: Albert and Jakobiec's Principles and Practice of Ophthalmology, 3rd edition,. Ed(s) Albert/Miller. Elsevier: Philadelphia, Pennsylvania, 3367-3378, 2008.

Grant & Contract Support

Title: The Cancer Genome Atlas (TCGA) -Uveal Melanoma Project
Funding Source: National Cancer Institute
Role: Principal Investigator
Duration: 2013 - 2014
 
Title: Multi-institutional Orbital & Ocular Oncology Database
Funding Source: American Society of Ophthalmic Plastic & Reconstructive Surgery
Role: Principal Investigator
Duration: 2011 - present
 
Title: "A double-blind study evaluating the safety and efficacy of cyclosporine ophthalmic emulsion 0.05% [Restasis] in subjects with epiphora secondary to docetaxel [Taxotere] for various cancers"
Funding Source: Allergan Pharmaceutical Corporation
Role: Principal Investigator
Duration: 2008 - 2011
 
Title: "Integrin-mediated regulation of epithelial cell growth"
Funding Source: American Cancer Society Institutional Grant
Role: Collaborator
Principal Investigator: Joseph McCarty, Ph.D.
Duration: 2008 - 2011
 
Title: "Radioimmunotherapy with Yttrium 90-labeled (90Y) for Low-Grade Follicular Non-Hodgkin's Lymphoma of the Orbit"
Funding Source: IDEC Pharmaceuticals Corporation
Role: Principal Investigator
Duration: 2003 - 2010

Last updated: 3/7/2014