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Bradley W. McIntyre, Ph.D.

Present Title & Affiliation

Primary Appointment

Professor, Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
7455 Fannin St.
Unit Number: 902
Houston, TX 77054
Room Number: SCR4.2026

Education & Training

Degree-Granting Education

1984 University of Texas, Austin, TX, PHD, Biological Sciences
1979 Texas Tech University, Lubbock, TX, BS, Microbiology

Postgraduate Training

1984-1987 Research Fellowship, Immunology, Stanford University School of Medicine, Stanford, CA, Dr. Peter Parham; Dr. Irving L. Weissman


Academic Appointments

Associate Professor, Department of Immunology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 1993-1999
Regular Member, Graduate Faculty, The University of Texas Graduate School of Biomedical Sciences, Houston, TX, 1987-present
Assistant Professor, Department of Immunology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 1987-1993

Selected Publications

Peer-Reviewed Original Research Articles

1. Cimo AM, Ahmed Z, McIntyre BW, Lewis DE, Ladbury JE. CD25 and CD69 induction by α4β1 outside-in signalling requires TCR early signalling complex proteins. Biochem J 454(1):109-21, 2013. PMCID: PMC3749870.
2. Vanderslice P, Biediger RJ, Woodside DG, Brown WS, Khounlo S, Warier ND, Gundlach CW, Caivano AR, Bornmann WG, Maxwell DS, McIntyre BW, Willerson JT, Dixon RA. Small molecule agonist of very late antigen-4 (VLA-4) integrin induces progenitor cell adhesion. J Biol Chem 288(27):19414-28, 2013. PMCID: PMC3707645.
3. Lee YC, Jin JK, Cheng CJ, Huang CF, Song JH, Huang M, Brown WS, Zhang S, Yu-Lee LY, Yeh ET, McIntyre BW, Logothetis CJ, Gallick GE, Lin SH. Targeting constitutively activated β1 integrin inhibits prostate cancer metastasis. Mol Cancer Res 11(4):405-17, 2013. PMCID: PMC3631285.
4. Fiorcari S, Brown WS, McIntyre BW, Estrov Z, Maffei R, O'Brien S, Sivina M, Hoellenriegel J, Wierda WG, Keating MJ, Ding W, Kay NE, Lannutti BJ, Marasca R, Burger JA. The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells. PLoS One 8(12):e83830, 2013. PMCID: PMC3871531.
5. Shah N, Cabanillas F, McIntyre B, Feng L, McLaughlin P, Rodriguez MA, Romaguera J, Younes A, Hagemeister FB, Kwak L, Fayad L. Prognostic value of serum CD44, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 levels in patients with indolent non-Hodgkin lymphomas. Leuk Lymphoma 53(1):50-6, 2012. PMID: 21895545.
6. Sergeeva A, Alatrash G, He H, Ruisaard K, Lu S, Wygant J, McIntyre BW, Ma Q, Li D, St John L, Clise-Dwyer K, Molldrem JJ. An anti-PR1/HLA-A2 T cell receptor-like antibody mediates complement dependent cytotoxicity against acute myeloid leukemia progenitor cells. Blood 117(16):4262-72, 2011. PMCID: PMC3087478.
7. Gundlach CW, Caivano A, Cabreira-Hansen Mda G, Gahremanpour A, Brown WS, Zheng Y, McIntyre BW, Willerson JT, Dixon RA, Perin EC, Woodside DG. Synthesis and evaluation of an anti-MLC1 × anti-CD90 bispecific antibody for targeting and retaining bone-marrow-derived multipotent stromal cells in infarcted myocardium. Bioconjug Chem 22(8):1706-14, 2011. PMCID: PMC3250066.
8. Carreño R, Brown WS, Li D, Hernandez JA, Wang Y, Kim TK, Craft JW, Komanduri KV, Radvanyi LG, Hwu P, Molldrem JJ, Legge GB, McIntyre BW, Ma Q. 2E8 binds to the high-affinity I-domain in a metal ion dependent manner: A second generation monoclonal antibody selectively targeting activated LFA-1. J Biol Chem 285(43):32860-8, 2010. PMCID: PMC2963386.
9. Sood AK, Armaiz-Pena GN, Halder J, Nick AM, Stone RL, Hu W, Carroll AR, Spannuth WA, Deavers MT, Allen JK, Han LY, Kamat AA, Shahzad MM, McIntyre BW, Diaz-Montero CM, Jennings NB, Lin YG, Merritt WM, DeGeest K, Vivas-Mejia PE, Lopez-Berestein G, Schaller MD, Cole SW, Lutgendorf SK. Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. J Clin Invest 120(5):1515-23, 2010. PMCID: PMC2860925.
10. Kim TK, Billard MJ, Wieder ED, McIntyre BW, Komanduri KV. Co-engagement of alpha(4)beta(1) integrin (VLA-4) and CD4 or CD8 is necessary to induce maximal Erk1/2 phosphorylation and cytokine production in human T cells. Hum Immunol 71(1):23-8, 2010. PMCID: PMC2795106.
11. Mitchell JS, Brown WS, Woodside DG, Vanderslice P, McIntyre BW. Clustering T cell GM1 lipid rafts increases cellular resistance to shear on fibronectin through changes in integrin affinity and cytoskeletal dynamics. Immunol Cell Biol 87(4):324-36, 2009. PMCID: PMC2679097.
12. Wang Y, Li D, Nurieva R, Yang J, Sen M, Carreño R, Lu S, McIntyre BW, Molldrem JJ, Legge GB, Ma Q. LFA-1 affinity regulation is necessary for the activation and proliferation of naive T cells. J Biol Chem 284(19):12645-53, 2009. PMCID: PMC2675993.
13. Billard MJ, McIntyre BW. CD45RA T-cell activation without proliferation by a partial agonist monoclonal antibody to beta1 integrin. Immunol Cell Biol 86(4):381-4, 2008. PMID: 18195724.
14. Huang B, Sun Y, Maciejewska I, Qin D, Peng T, McIntyre BW, Wygant J, Butler WT, Qin C. Distribution of SIBLING proteins in the organic and inorganic phases of rat dentin and bone. Eur J Oral Sci 116(2):104-112, 2008. PMCID: PMC2666982.
15. Qin C, Huang B, Wygant JN, McIntyre BW, McDonald CH, Cook RG, Butler WT. A chondroitin sulfate chain attached to the bone dentin matrix protein 1 NH2-terminal fragment. J Biol Chem 281(12):8034-40, 2006. PMID: 16421105.
16. Woodside DG, Kram RM, Mitchell JS, Belsom T, Billard MJ, McIntyre BW, Vanderslice P. Contrasting roles for domain 4 of VCAM-1 in the regulation of cell adhesion and soluble VCAM-1 binding to integrin alpha4beta1. J Immunol 176(8):5041-9, 2006. PMID: 16585601.
17. Wang YH, Ito T, Wang YH, Homey B, Watanabe N, Martin R, Barnes CJ, McIntyre BW, Gilliet M, Kumar R, Yao Z, Liu YJ. Maintenance and polarization of human t(h)2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells. Immunity 24(6):827-38, 2006. PMID: 16782037.
18. Diaz-Montero CM, Wygant JN, McIntyre BW. PI3-K/Akt-mediated anoikis resistance of human osteosarcoma cells requires Src activation. Eur J Cancer 42(10):1491-500, 2006. PMID: 16759849.
19. Diaz-Montero CM, McIntyre BW. Acquisition of anoikis resistance in human osteosarcoma cells does not alter sensitivity to chemotherapeutic agents. BMC Cancer 5:39, 2005. PMID: 15829011.
20. Baba O, Qin C, Brunn JC, Wygant JN, McIntyre BW, Butler WT. Colocalization of dentin matrix protein 1 and dentin sialoprotein at late stages of rat molar development. Matrix Biol 23(6):371-79, 2004. PMID: 15533758.
21. Baba O, Qin C, Brunn JC, Jones JE, Wygant JN, McIntyre BW, Butler WT. Detection of dentin sialoprotein in rat periodontium. Eur J Oral Sci 112(2):163-70, 2004. PMID: 15056114.
22. Anvari B, Torres JH, McIntyre BW. Regulation of pseudopodia localization in lymphocytes through application of mechanical forces by optical tweezers. J Biomed Opt 9(5):865-72, 2004. PMID: 15447007.
23. Diaz-Montero CM, McIntyre BW. Acquisition of anoikis resistance in human osteosarcoma cells. Eur J Cancer 39(16):2395-2402, 2003. PMID: 14556933.
24. Marco RA, Diaz-Montero CM, Wygant JN, Kleinerman ES, McIntyre BW. Alpha 4 integrin increases anoikis of human osteosarcoma cells. J Cell Biochem 88:1038-47, 2003. PMID: 12616540.
25. Woodside DG, Wooten DK, Teague TK, Miyamoto YJ, Caudell EG, Udagawa T, Andruss BF, McIntyre BW. Control of T lymphocyte morphology by the GTPase Rho. BMC Cell Biol 4:2, 2003. PMID: 12600279.
26. Qin C, Brunn JC, Baba O, Wygant JN, McIntyre BW, Butler WT. Dentin sialoprotein isoforms: detection and characterization of a high molecular weight dentin sialoprotein. Eur J Oral Sci 111:235-42, 2003. PMID: 12786955.
27. Miyamoto YJ, Mitchell JS, McIntyre BW. Physical association and functional interaction between beta1 integrin and CD98 on human T lymphocytes. Mol Immunol 39:739-51, 2003. PMID: 12531285.
28. Mitchell JS, Kanca O, McIntyre BW. Lipid microdomain clustering induces a redistribution of antigen recognition and adhesion molecules on human T lymphocytes. J Immunol 168:2737-44, 2002. PMID: 11884440.
29. Lee LY, Miyamoto YJ, McIntyre BW, Hook M, McCrea KW, McDevitt D, Brown EL. The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell-mediated responses. J Clin Invest 110:1461-71, 2002. PMID: 12438444.
30. Savary CA, Grazziuti ML, Przepiorka D, Tomasovic SP, McIntyre BW, Woodside DG, Pellis NR, Pierson DL, Rex JH. Characteristics of human dendritic cells generated in a microgravity analog culture system. In Vitro Cell Dev Biol Anim 37:216-22, 2001. PMID: 11409686.
31. Caruso DA, McIntyre BW. In an adhesion dependent human gastric adenocarcinoma cell line, integrin ligation without adhesion rescues from anoikis but is not sufficient for cell cycle progression. Cell Death Differ 8:665-78, 2001. PMID: 11464211.
32. Lutty GA, Taomoto M, Cao J, McLeod DS, Vanderslice P, McIntyre BW, Fabry ME, Nagel RL. Inhibition of TNF-alpha-induced sickle RBC retention in retina by a VLA-4 antagonist. Invest Ophthalmol Vis Sci 42:1349-55, 2001. PMID: 11328750.
33. Miyamoto YJ, Wann ER, Fowler T, Duffield E, Hook M, McIntyre BW. The fibronectin-binding MSCRAMM FnbpA of Staphylococcus aureus can mediate human T lymphocyte adhesion and coactivation. J Immunol 166:5129-38, 2001. PMID: 11290795.
34. Warren AP, Patel K, Miyamoto Y, Wygant JN, Woodside DG, McIntyre BW. Convergence between CD98 and integrin-mediated T-lymphocyte co-stimulation. Immunology 99(1):62-68, 2000. PMCID: PMC2327130.
35. Trial J, Baughn RE, Wygant JN, McIntyre BW, Birdsall HH, Youker KA, Evans A, Entman ML, Rossen RD. Fibronectin fragments modulate monocyte VLA-5 expression and monocyte migration. J Clin Invest 104:419-30, 1999. PMID: 10449434.
36. Woodside DG, Long DA, McIntyre BW. Intracellular analysis of interleukin-2 induction provides direct evidence at the single cell level of differential coactivation requirements for CD45RA+ and CD45RO+ T cell subsets. J Interferon Cytokine Res 19:769-79, 1999. PMID: 10454348.
37. Wooten DK, Teague TK, McIntyre BW. Separation of integrin-dependent adhesion from morphological changes based on differential PLC specificities. J Leukoc Biol 65:127-36, 1999. PMID: 9886255.
38. Martins MD, Rodriguez LJ, Savary CA, Grazziutti ML, Deshpande D, Cohen DM, Cowart RE, Woodside DG, McIntyre BW, Anaissie EJ, Rex JH. Activated lymphocytes reduce adherence of Aspergillus fumigatus. Med Mycol 36:281-9, 1998. PMID: 10075497.
39. Woodside DG, Wooten DK, McIntyre BW. Adenosine diphosphate (ADP)-ribosylation of the guanosine triphosphatase (GTPase) rho in resting peripheral blood human T lymphocytes results in pseudopodial extension and the inhibition of T cell activation. J Exp Med 188:1211-21, 1998. PMID: 9763600.
40. Vanderslice P, Munsch CL, Rachal E, Erichsen D, Sughrue KM, Truong AN, Wygant JN, McIntyre BW, Eskin SG, Tilton RG, Polverini PJ. Angiogenesis induced by tumor necrosis factor-agr; is mediated by alpha4 integrins. Angiogenesis 2:265-75, 1998. PMID: 14517466.
41. Woodside DG, McIntyre BW. Inhibition of CD28/CD3-mediated costimulation of naive and memory human T lymphocytes by intracellular incorporation of polyclonal antibodies specific for the activator protein-1 transcriptional complex. J Immunol 161:649-58, 1998. PMID: 9670939.
42. Savary CA, Grazziutti ML, Melichar B, Przepiorka D, Freedman RS, Cowart RE, Cohen DM, Anaissie EJ, Woodside DG, McIntyre BW, Pierson DL, Pellis NR, Rex JH. Multidimensional flow-cytometric analysis of dendritic cells in peripheral blood of normal donors and cancer patients. Cancer Immunol Immunother 45:234-40, 1998. PMID: 9439646.
43. Pellis NR, Goodwin TJ, Risin D, McIntyre BW, Pizzini RP, Cooper D, Baker TL, Spaulding GF. Changes in gravity inhibit lymphocyte locomotion through type I collagen. In Vitro Cell Dev Biol Anim 33:398-405, 1997. PMID: 9196900.
44. Szabo MC, Butcher EC, McIntyre BW, Schall TJ, Bacon KB. RANTES stimulation of T lymphocyte adhesion and activation: role for LFA-1 and ICAM-3. Eur J Immunol 27:1061-68, 1997. PMID: 9174593.
45. McIntyre BW, Woodside DG, Caruso DA, Wooten DK, Simon SI, Neelamegham S, Revelle JK, Vanderslice P. Regulation of human T lymphocyte coactivation with an alpha4 integrin antagonist peptide. J Immunol 158:4180-86, 1997. PMID: 9126978.
46. Yokoyama T, Nakano M, Bednarczyk JL, McIntyre BW, Entman M, Mann DL. Tumor necrosis factor-alpha provokes a hypertrophic growth response in adult cardiac myocytes. Circulation 95:1247-52, 1997. PMID: 9054856.
47. Udagawa T, McIntyre BW. ADP-ribosylation of the G protein Rho inhibits integrin regulation of tumor cell growth. J Biol Chem 271:12542-48, 1996. PMID: 8647863.
48. Udagawa T, Woodside DG, McIntyre BW. Alpha 4 beta 1 (CD49d/CD29) integrin costimulation of human T cells enhances transcription factor and cytokine induction in the absence of altered sensitivity to anti-CD3 stimulation. J Immunol 157:1965-72, 1996. PMID: 8757316.
49. Neelamegham S, Simon SI, McIntyre BW, Zygourakis K. Induction of homotypic lymphocyte aggregation: evidence for a novel activation state of the beta1 integrin. J Leukoc Biol 59:872-82, 1996. PMID: 8691073.
50. Yadav M, Hopwood VL, Multani AS, Mansfield PF, Takahashi Y, McIntyre BW, Udagawa T, Pathak S. Non-random primary and secondary chromosomal abnormalities in human gastric cancers. Anticancer Res 16:1787-95, 1996. PMID: 8712702.
51. Woodside DG, Teague TK, McIntyre BW. Specific inhibition of T lymphocyte coactivation by triggering integrin beta 1 reveals convergence of beta 1, beta 2, and beta 7 signaling pathways. J Immunol 157:700-6, 1996. PMID: 8752919.
52. Szabo M, McIntyre BW. Identification of two variants of the human integrin alpha 4 subunit. Mol Immunol 32:1453-54, 1995. PMID: 8643114.
53. Udagawa T, Hopwood VL, Pathak S, McIntyre BW. Integrin-mediated entry into S phase of human gastric adenocarcinoma cells. Clin Exp Metastasis 13:427-38, 1995. PMID: 7586801.
54. Asano T, McIntyre BW, Bednarczyk JL, Wygant JN, Kleinerman ES. Liposomal muramyl tripeptide upregulates adhesion molecules on the surface of human monocytes. Oncol Res 7:253-7, 1995. PMID: 8534931.
55. Champe M, McIntyre BW, Berman PW. Monoclonal antibodies that block the activity of leukocyte function-associated antigen 1 recognize three discrete epitopes in the inserted domain of CD11a. J Biol Chem 270:1388-94, 1995. PMID: 7530713.
56. Bednarczyk JL, Szabo MC, Wygant JN, Lazarovits AI, McIntyre BW. Identification of a combinatorial epitope expressed by the integrin alpha 4 beta 1 heterodimer involved in the regulation of cell adhesion. J Biol Chem 269:8348-54, 1994. PMID: 7510686.
57. Teague TK, Lazarovits AI, McIntyre BW. Integrin alpha 4 beta 7 co-stimulation of human peripheral blood T cell proliferation. Cell Adhes Commun 2:539-47, 1994. PMID: 7743139.
58. Teague TK, McIntyre BW. MAb 18D3 triggering of integrin beta 1 will prevent but not terminate proliferation of human T cells. Cell Adhes Commun 2:169-84, 1994. PMID: 7521762.
59. Teague TK, Munn L, Zygourakis K, McIntyre BW. Analysis of lymphocyte activation and proliferation by video microscopy and digital imaging. Cytometry 14:772-82, 1993. PMID: 8243206.
60. Munn LL, Glacken MW, McIntyre BW, Zygourakis K. Analysis of lymphocyte aggregation using digital image analysis. J Immunol Methods 166:11-25, 1993. PMID: 8228280.
61. Georas SN, McIntyre BW, Ebisawa M, Bednarczyk JL, Sterbinsky SA, Schleimer RP, Bochner BS. Expression of a functional laminin receptor (alpha 6 beta 1, very late activation antigen-6) on human eosinophils. Blood 82:2872-9, 1993. PMID: 8219235.
62. Bednarczyk JL, Wygant JN, Szabo MC, Molinari-Storey L, Renz M, Fong S, McIntyre BW. Homotypic leukocyte aggregation triggered by a monoclonal antibody specific for a novel epitope expressed by the integrin β 1 subunit: conversion of nonresponsive cells by transfecting human integrin α 4 subunit cDNA. J Cell Biochem 51:465-78, 1993. PMID: 7684386.
63. Savage CO, Hughes CC, McIntyre BW, Picard JK, Pober JS. Human CD4+ T cells proliferate to HLA-DR+ allogeneic vascular endothelium. Identification of accessory interactions. Transplantation 56:128-34, 1993. PMID: 7687392.
64. Udagawa T, McIntyre BW. A VLA-4 α chain specific monoclonal antibody enhances CD3-induced IL-2/IL-2 receptor-dependent T-cell proliferation. Lymphokine Cytokine Res 11:193-99, 1992. PMID: 1467362.
65. Bednarczyk JL, McIntyre BW. Expression and ligand-binding function of the integrin α4β1 (VLA-4) on neural-crest-derived tumor cell lines. Clin Exp Metastasis 10:281-90, 1992. PMID: 1535575.
66. Freedman AS, Munro JM, Morimoto C, McIntyre BW, Rhynhart K, Lee N, Nadler LM. Follicular non-Hodgkin's lymphoma cell adhesion to normal germinal centers and neoplastic follicles involves very late antigen-4 and vascular cell adhesion molecule-1. Blood 79:206-12, 1992. PMID: 1370204.
67. Schleimer RP, Sterbinsky SA, Kaiser J, Bickel CA, Klunk DA, Tomioka K, Newman W, Luscinskas FW, Gimbrone MA, Jr, McIntyre BW, et al. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1. J Immunol 148:1086-092, 1992. PMID: 1371130.
68. Bednarczyk JL, Szabo MC, McIntyre BW. Post-translational processing of the leukocyte integrin α4β1 . J Biol Chem 267:25274-281, 1992. PMID: 1281155.
69. Bednarczyk JL, Teague TK, Wygant JN, Davis LS, Lipsky PE, McIntyre BW. Regulation of T cell proliferation by anti-CD49d and anti-CD29 monoclonal antibodies. J Leukoc Biol 52:456-62, 1992. PMID: 1383369.
70. Bednarczyk JL, Carroll SM, Marin C, McIntyre BW. Triggering of the proteinase dipeptidyl peptidase IV (CD26) amplifies human T lymphocyte proliferation. J Cell Biochem 46:206-218, 1991. PMID: 1723066.
71. Bednarczyk JL, McIntyre BW. A monoclonal antibody to VLA-4 α chain (CDw49d) induces homotypic lymphocyte aggregation. J Immunol 144:777-84, 1990. PMID: 2295817.
72. Freedman AS, Munro JM, Rice GE, Bevilacqua MP, Morimoto C, McIntyre BW, Rhynhart K, Pober JS, Nadler LM. Adhesion of human B cells to germinal centers in vitro involves VLA-4 and INCAM-110. Science 249:1030-33, 1990. PMID: 1697696.
73. Davis LS, Oppenheimer-Marks N, Bednarczyk JL, McIntyre BW, Lipsky PE. Fibronectin promotes proliferation of naive and memory T cells by signaling through both the VLA-4 and VLA-5 integrin molecules. J Immunol 145:785-93, 1990. PMID: 1695644.
74. Kadiyala RK, McIntyre BW, Krensky AM. Molecular cloning and characterization of WP34, a phosphorylated human lymphocyte differentiation and activation antigen. Eur J Immunol 20:2417-423, 1990. PMID: 2174784.
75. Danska JS, McIntyre BW, McDevitt HO, Weissman IL. Structural similarity between a primitive chordate membrane heterodimer and lymphocyte antigen receptors. Int Immunol 2:795-802, 1990. PMID: 2278999.
76. Ullrich SE, McIntyre BW, Rivas JM. Suppression of the immune response to alloantigen by factors released from ultraviolet-irradiated keratinocytes. J Immunol 145:489-98, 1990. PMID: 2142179.
77. Trial J, McIntyre BW. Suppressor cell clones specific for ultraviolet radiation-induced tumors. Function and surface proteins. J Immunol 145:2044-049, 1990. PMID: 1975821.
78. Nairn RS, McIntyre BW, Richie ER, Allison JP. Characterization of env gene recombination in x-ray-induced thymomas of C57BL/6 mice. Mol Carcinog 2:1-5, 1989. PMID: 2675902.
79. Kaba DS, McIntyre BW, Kripke ML, Goodenow RS, Schreiber H, Ananthaswamy HN. Generation of antigenic variants from a nonantigenic murine tumor cell line by transfection with a gene encoding a novel tumor-specific transplantation antigen. Cancer Res 49:38-43, 1989. PMID: 2783244.
80. Holzmann B, McIntyre BW, Weissman IL. Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha. Cell 56:37-46, 1989. PMID: 2463092.
81. McIntyre BW, Evans EL, Bednarczyk JL. Lymphocyte surface antigen L25 is a member of the integrin receptor superfamily. J Biol Chem 264:13745-50, 1989. PMID: 2788163.
82. Price JE, Aukerman SL, Ananthaswamy HN, McIntyre BW, Schackert G, Schackert HK, Fidler IJ. Metastatic potential of cloned murine melanoma cells transfected with activated c-Ha-ras. Cancer Res 49:4274-281, 1989. PMID: 2663141.
83. Clayberger C, Krensky AM, McIntyre BW, Koller TD, Parham P, Brodsky F, Linn DJ, Evans EL. Identification and characterization of two novel lymphocyte function-associated antigens, L24 and L25. J Immunol 138:1510-514, 1987. PMID: 3492556.
84. Clayberger C, Dyer, B, McIntyre B, Koller TD, Hardy B, Parham P, Lanier L, Krensky AM. Function and cell distribution of KC-1, a novel natural killer cell-associated antigen. Journal of Immunology 136:1537-1541, 1986.
85. Saunders PH, McIntyre BW, Lawlor DA, Bridges WJ, Allison JP. The congenic mutant B6.C-H-2bm-1 (H-2bm-1) serological response to the T-cell receptor on EL4. Cell Immunol 101:586-92, 1986. PMID: 3757049.
86. Kline K, Allison JP, McIntyre BW, Sanders BG. Immunochemical characterization of differentiation and age-related cell surface antigens expressed by chicken erythrocytes. Cancer Res 44:3576-583, 1984. PMID: 6378372.
87. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre BW, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell 35(1):295-302, 1983. PMID: 6605199.
88. Allison JP, McIntyre BW, Bloch D. Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody. J Immunol 129:2293-300, 1982. PMID: 6181166.
89. Glenney J Jr, Kaulfus PJ, McIntyre BW, Walborg EF Jr. Identification and partial characterization of the major galactoproteins present at the surface of AS-30D hepatocellular carcinoma cells. Cancer Res 40:2853-59, 1980. PMID: 7388836.

Invited Articles

1. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. Pillars Article: The Major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. J Immunol 176(5):2683-90, 2006. PMID: 16493022.
2. Allison JP, McIntyre BW, Bloch D.. Pillar Article: Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody. 1982. J Immunol 174(3):1144-1151, 2005. PMID: 15661866.
3. Miyamoto YJ, Andruss BF, Mitchell JS, Billard MJ, McIntyre BW. Diverse roles of integrins in human T lymphocyte biology. Immunol Res 27(1):71-84, 2003. PMID: 12637769.
4. McIntyre BW, Cabanillas FF. Lymphoma adhesion molecules. Diagnostic Oncology 4:6-11, 1994.
5. McIntyre B, Bednarczyk JL, Passini CA, Szabo MC, Udagawa T, Wygant JN. Integrins: Cell adhesion receptors in health and disease. The Cancer Bulletin 4:6-11, 1991.
6. Allison JP, McIntyre BW, Ridge LL, Gross-Pelose J, Lanier LL. Molecular characterization of the murine T cell antigen receptor and associated structures. Fed Proc 44(13):2870-3, 1985. PMID: 2412897.
7. Allison JP, Ridge L, Lund J, Gross-Pelose J, Lanier L, McIntyre B. The murine T cell antigen receptor and associated structures. Immunol Rev 81:145-160, 1984. PMID: 6210241.

Book Chapters

1. McIntyre BW, Teague TK, Woodside DG, Wooten DK.. Digital image analysis of lymphocyte activation. In: T Cell Protocols: Development and Activation, Methods in Molecular Biology series. 134. Ed(s) KP Kearse. Humana Press: Totowa, NJ, 257-63, 2000. ISBN: 10730263.
2. Neff PT, McIntyre BW. Adhesion molecules in non-Hodgkin's lymphoma. In: Advances in Lymphoma Research, Cancer Treatment and Research series. 85. Ed(s) F Cabanillas, MA Rodriguez. Kluwer Academic: Boston, MA, 119-139, 1996. ISBN: 9043779.
3. Bednarczyk JL, McIntyre BW, Cohen PJ, Kuo HR, Schwartz RA, van Vloten WA, Lambert WC. Terms and abbreviations used in studies of cutaneous lymphoproliferative phenomena. In: Basic Mechanisms of Physiologic and Aberrant Lymphoproliferation in the Skin. Ed(s) WC Lambert, B Giannotti, WA van Vloten. Plenum Press: New York, NY, 579-611, 1995.
4. Danska J, McIntyre BW, Sabinga N, Saito Y, McDevitt H, Weissman I. Molecular approaches to cell surface interactions in the response of a marine protochordate. In: Invertebrate Historecognition. Ed(s) RK Grosberg, D Hedgecock, K Nelson. Plenum Press: New York, NY, 1988.
5. McIntyre BW, Lanier LL, Allison JP. The Murine T Cell Receptor. In: Antigen-specific T Cell Receptors and Factors. Ed(s) JJ Marchalonis. CRC Press: Boca Raton, FL, 65-76, 1987.
6. Allison JP, McIntyre BW, Cheung FC-Y, and Lanier LL. Molecular Characterization of the Murine T Cell Antigen Receptor. In: Regulation of the Immune System, UCLA Symposia on Molecular and Cellular Biology. 18. Ed(s) H Canor, L Chess, EE Sercarz. Alan R. Liss: New York, NY, 1984.
7. Marrack P, Kubo R, Haskins K, Hannum C, White J, Pigeon M, Endres R, Shimonkevitz R, McIntyre B, Allison J, Trowbridge I, Kappler J. T Cell Hybridomas Use in Studying T Cell Receptors for Antigen Plus MHC. In: Progress in Immunology V. Ed(s) Y Yamamura, T Tada. Academic Press: Orlando, FL, 735-744, 1984.
8. McIntyre BW, Allison JP. The Mouse T Cell Receptor: Structural Heterogeneity of Molecules of Normal T Cells Defined by Xenoantiserum. In: The Year Book of Cancer. Ed(s) RL Clark, RW Cumley. Year Book Medical: Chicago, IL, 315-317, 1984.
9. Allison JP, McIntyre BW. The murine T cell receptor: A proposed structure. In: Progress in Immunology V. Ed(s) Y. Yamamura, T Tada. Academic Press: Orlando, FL, 755-762, 1984.
10. Allison JP, McIntyre BW, Irvin J, Bloch D, Kitto GB. Monoclonal Antibody to Tumor-specific Epitope of Murine Lymphoma Cells: Use in Characterization of Antigen and in Immunotherapy. In: Hybridomas and Cellular Immortality. Ed(s) BH Tom and JP Allison. Plenum Publishing: New York, NY, 201-220, 1983.

Grant & Contract Support

Title: Training Program in Cancer Immunobiology
Funding Source: NIH/NCI
Role: Principal Investigator
Duration: 8/4/2010 - 7/31/2015

Last updated: 7/17/2014