Skip to Content

Brian Hobbs, PhD

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Biostatistics, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX

Research Interests

Bayesian analysis

Clinical trial design

Meta-analysis

Survival analysis

Adaptive design in the presence of historical controls

Functional imaging

Education & Training

Degree-Granting Education

2010 University of Minnesota, Minneapolis, MN, PHD, Biostatistics
2007 University of Minnesota, Minneapolis, MN, MS, Biostatistics
2004 University of Iowa, Iowa City, IA, BA, Anthropology
2004 University of Iowa, Iowa City, IA, Minor, Computer Science

Experience/Service

Academic Appointments

Postdoctoral Fellow, Department of Biostatistics, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/2010-9/2011

Selected Publications

Peer-Reviewed Original Research Articles
1. Hobbs BP, Carlin BP, Sargent DJ. Adaptive adjustment of the randomization ratio using historical control data. Clinical Trials. In Press.
2. Ng CS, Hobbs BP, Anderson EF, Herron DH, Charnsangavej C, Yao J. Effect of duration of scan acquisition on CT perfusion values in metastases to the liver from neuroendocrine tumors and normal liver. Radiology. In Press.
3. Nute JL, Rong J, Stevens DM, Darensbourg BJ, Cheng J, Wei W, Hobbs BP, Cody DD. Evaluation of over 100 scanner-years of computed tomography daily quality control data. Medical Physics. In Press.
4. Hobbs BP, Sargent DJ, Carlin BP. Commensurate priors for incorporating historical information in clinical trials using general and generalized linear models. Bayesian Analysis 7(3):639-674, 2012.
5. Schellingerhout D, Leroux LG, Hobbs BP, Bredow S. Impairment of retrograde neuronal transport in oxaliplatin-induced neuropathy demonstrated by molecular imaging. PLoS One 7(9):e45776, 2012. e-Pub 9/2012. PMCID: PMC3447809.
6. Hobbs BP, Carlin BP, Mandrekar SJ, Sargent DJ. Hierarchical commensurate and power prior models for adaptive incorporation of historical information in clinical trials. Biometrics 67(3):1047-56, 9/2011. e-Pub 3/2011. PMCID: PMC3134568.
7. Hobbs BP, Carlin BP. Practical Bayesian design and analysis for drug and device clinical trials. J Biopharm Stat 18(1):54-80, 2008. PMID: 18161542.
8. Rauch GM, Kuerer HM, Scoggins ME, Fox PS, Benveniste AP, Park YM, Lari SA, Hobbs BP, Krishnamurthy S, Yang WT. Clinicopathologic, mammographic, and sonographic features in 1187 patients with pure ductal carcinoma in situ of the breast by estrogen receptor status. Submitted.

Abstracts
1. MacLellan C, Hobbs BP, Chasen B, Murthy R, Mahvash A, Kappadath SC. Absorbed dose differences in 90Y microsphere therapy between pre-treatment 99m Tc-MAA and post-treatment 90Y scans. Journal of Nuclear Medicine 53 (Supplement 1):1494, 2012.
2. MacLellan C, Hobbs BP, Chasen B, Mahvash A, Murthy R, Kappadath SC. Absorbed dose differences in 90Y microsphere therapy between pre-treatment 99mTc-MAA and post-treatment 90Y scans. Australian and New Zealand Society of Nuclear Medicine, 2012.
3. Martaindale S, Hobbs BP, Yang WT, Albarez R, Krishnamurthy S, Le-Petross HC. Assessment of residual disease using mammography (MG), sonography (US), and magnetic resonance imaging (MRI) in patients (pts) with inflammatory breast cancer (IBC) who received neoadjuvant chemotherapy (NAC). Radiological Society of North America (#LL-BRS-SU5A), 2012.
4. Rauch GM, Kuerer HM, Scoggins ME, Benveniste AP, Fox PS, Yang WT, Park YM, Lari SA, Hobbs BP, Krishnamurthy S,. Biologic subtype and imaging correlates of 1,187 patients with pure ductal carcinoma in situ of the breast. Radiological Society of North America (#SSM02-04), 2012.

Book Chapters
1. Hobbs BP, Lee JJ. Adaptive Trial Designs. In: Handbook of Statistics in Clinical Oncology, 3rd. Ed(s) Crowley J, Hoering A, Ankerst DP. Chapman and Hall/CRC Press: Boca Raton, FL, 2012. ISBN: 978-1439862001.

Grant & Contract Support

Title: Statistical Methods and Software for More Efficient, Ethical, and Affordable Clinical Trials
Funding Source: NIH/NCI (Subcontract from the University of Minnesota)
Role: Principal Investigator (subcontract)
Principal Investigator: Brad Carlin
Duration: 6/1/2012 - 5/31/2014
 
Title: Multimode laser optoacoustic tomography system for breast cancer care
Funding Source: NIH/NCI (Subcontract from TomoWaves Laboratory)
Role: Co-Investigator
Principal Investigator: Alexander Oraevsky
Duration: 5/1/2012 - 3/31/2017
 
Title: Personalizing Nanoparticle Therapy
Funding Source: NIH/NCI
Role: Collaborator
Principal Investigator: Vikas Kundra
Duration: 3/1/2011 - 2/29/2016
 
Title: Spatially Accurate Deformable Image Registration for Thoracic CT Applications
Funding Source: NIH/NIGMS
Role: Co-Investigator
Principal Investigator: Thomas Guerrero
Duration: 9/30/2010 - 6/30/2015
 
Title: Cancer Center Support Grant - Biostatistics Shared Resource (PP-SR21)
Funding Source: NIH/NCI
Role: Statistician
Principal Investigator: Ronald DePinho
Duration: 9/4/1998 - 6/30/2013

Last updated: 5/15/2013