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David J. Yang, Ph.D.

Present Title & Affiliation

Primary Appointment

Professor (tenured), Department of Cancer Systems Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Professor, The University of Texas Graduate School of Biomedical Sciences, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
1881 East Road
Unit Number: 1900
Houston, TX 77054-1900
Room Number: 3SCR2.3420
Phone: 713-794-1053
Fax: 713-794-5456
Email: DYang@mdanderson.org

Education & Training

Degree-Granting Education

1983 Northeast Louisiana University, Monroe, LA, PHD, Medicinal Chemistry
1978 Taipei Medical College, Taipei, Taiwan, BS, School of Pharmacy

Postgraduate Training

1/1983-1/1985 Postdoctoral Fellowship, Marshall University School of Medicine, Huntington, WV, Gary O. Rankin, Ph.D.

Experience/Service

Academic Appointments

Associate Professor (tenured) and Associate Chemist, Department of Cancer Systems Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/1994-1/2007
Associate Professor, The University of Texas Graduate School of Biomedical Sciences, Houston, TX, 9/1994-1/2007
Assistant Professor (tenure track), Department of Nuclear Medicine, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 8/1988-8/1994
Assistant Chemist, Department of Nuclear Medicine, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 8/1988-8/1994
Research Investigator, Department of Internal Medicine, Cyclotron/PET Facility, The University of Michigan, Ann Arbor, MI, 1/1987-7/1988
Teaching Assistant, Northeast Louisiana University School of Pharmacy, Monroe, LA, 9/1980-5/1983
Research Assistant, Northeast Louisiana University School of Pharmacy, Monroe, LA, 9/1978-8/1980

Administrative Appointments/Responsibilities

Chief of Radiotheranostic Development, Department of Cancer Systems Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 6/2006-present
Director of Radiopharmaceutical Development, Department of Nuclear Medicine, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/1994-8/2003
Assistant Director, Senior Research and Management, Pharmacology Division, Panlabs Taiwan, Ltd.(subsidiary company of Panlabs, Inc., Seattle, WA), Taipei, Taiwan, 1/1986-12/1986

Other Appointments/Responsibilities

Pharmacist, Jen-Ai Hospital, Taipei, Taiwan, 1977-1978
English Tutor, Taipei Chien-Kuo Supplementary Senior High School, Taipei, Taiwan, 1975-1978

Consultantships

Sumitomo Heavy Industries, Tokyo, Japan, 1999-2004
Anzai Medical Company, Tokyo, Japan, 1997-2005
Nihon Medi-Physics Pharmaceutical Company, Tokyo, Japan, 1996-1998

Institutional Committee Activities

Member, Institutional NMR Core Facility Advisory Committee, 2005-present
Member, Faculty Senate, 2005-present
Member, Institutional Biosafety Committee, 2004-2006
Member, Radioactive Drug Research Committee, 2002-2004
Member, Study Section Review Committee, 2000-2003
Member, Isotope Committee, 1995-1998
Member, UT M.D. Anderson Associates, 1989-present

Honors and Awards

2009 Award for Mentoring Excellence, Robert M. Chamberlain Distinguished Mentor Award, University of Texas MD Anderson Cancer Center Postdoctoral Association
2007 Award for the 9th International Symposium on Future Medical Engineering based on Bionanotechnology, Center of Excellence,Tohoku University (Professor M. Itoh), Sendai Japan
2004 Award for 14th Annual Winfield Evans Lecture, Southwestern Chapter of the Society of Nuclear Medicine
2004 Award for 8th Asia Oceania Congress of Nuclear Medicine and Biology, Asia Oceania Congress of Nuclear Medicine and Biology
1997 Certificate of Merit-Honorable Mention award winning scientific exhibit, Society of Nuclear Medicine
1996 Award for Distinguished Young Investigator, 6th Asia and Oceania Congress of Nuclear Medicine and Biology
1982 Honorary Citizen, City of Monroe, LA
1982 Honorary Citizen, City of West Monroe, LA
1979-1981 President, Chinese Student Association, Northeast Louisiana University
1979-1980 Vice President, International Student Association, Northeast Louisiana University

Selected Publications

Peer-Reviewed Original Research Articles

1. Tsao N, Wang CH, Her LJ, Tzen KY, Chen JY, Yu DF, Yang DJ. Development of 68Ga-glycopeptide as an imaging probe for tumor angiogenesis. J Biomed Biotechnol 2011:267206, 2011. e-Pub 4/2011. PMCID: PMC3085313.
2. Kong FL, Zhang Y, Ali MS, Oh C, Mendez R, Kohanim S, Tsao N, Chanda M, Huang WC, Yang DJ. Synthesis of (99m)Tc-EC-AMT as an imaging probe for amino acid transporter systems in breast cancer. Nucl Med Commun 31(8):699-707, 8/2010. PMID: 20495499.
3. Gong J, Yang DJ, Kohanim S, Angelo LS, Kurzrock R. Molecular imaging of gefitinib activity in an epidermal growth factor receptor (EGFR)-bearing xenograft model. Cancer Biol Ther 8(23):2239-47, 12/2009. e-Pub 12/2009. PMID: 19823028.
4. Schechter NR, Erwin WD, Yang DJ, Kim EE, Munden RF, Forster K, Taing LC, Cox JD, Macapinlac HA, Podoloff DA. Radiation dosimetry and biodistribution of (99m)Tc-ethylene dicysteine-deoxyglucose in patients with non-small-cell lung cancer. Eur J Nucl Med Mol Imaging 36(10):1583-91, 10/2009. e-Pub 4/2009. PMCID: PMC2758190.
5. Kurihara H, Yang DJ, Cristofanilli M, Erwin WD, Yu DF, Kohanim S, Mendez R, Kim EE. Imaging and dosimetry of 99mTc EC annexin V: preliminary clinical study targeting apoptosis in breast tumors. Appl Radiat Isot 66(9):1175-82, 9/2008. e-Pub 1/2008. PMCID: PMC2562036.
6. Wei IC, Tsao N, Huang YH, Ho YS, Wu CC, Yu DF, Yang DJ. 99m Tc-glycopeptide: synthesis, biodistribution and imaging in breast tumor-bearing rodents. Appl Radiat Isot 66(3):320-31, 3/2008. e-Pub 10/2007. PMID: 18036826.
7. Bourn WM, Yang DJ, Davisson JN. Effect of ketamine enantiomers on sound-induced convulsions in epilepsy prone rats. Pharmacol Res Commun 15(9):815-24, 10/1983. PMID: 6647526.

Grant & Contract Support

Title: Polymeric Conjugates for Disease Targeting
Funding Source: HOPAX Chems, MFG, Co., Ltd
Role: Principal Investigator
Duration: 4/1/2013 - 4/1/2018
 
Title: Development of Bone-seeking Agents for PET
Funding Source: Daiichi Radioisotope Laboratories, Ltd.
Role: Principal Investigator
Duration: 11/2006 - 11/2008
 
Title: Oligosaccharide Conjugates for Dual Imaging and Radio/Chemotherapy: Composition, Manufacturing and Applications (MDA04-110
Funding Source: Cell Point Biotechnology Company
Role: Principal Investigator
Duration: 9/1/2005 - 12/2016
 
Title: Anti-neoplastic Effect of a Novel Platinum- complex on Cisplatin-sensitive and Resistant Ovarian Cancer in Vitro and in Vivo
Funding Source: MDACC IRG
Role: Co-Principal Investigator
Principal Investigator: Hu W
Duration: 4/1/2005 - 4/1/2006
 
Title: N4-Technology for Tumor Targeted Imaging and Therapy
Funding Source: Cell>Point Biotechnology Company
Role: Principal Investigator
Duration: 3/1/2005 - 12/2016
 
Title: Formulation of Radiolabeled Glycopeptide for PET and SPECT Imaging (MDA04-063)
Funding Source: HOPAX Chems, MFG, Co., Ltd
Role: Principal Investigator
Duration: 9/1/2004 - 8/1/2006
 
Title: Molecular Imaging with Peptide Conjugates (MDA03-026)
Funding Source: TRS Company
Role: Principal Investigator
Duration: 9/1/2004 - 8/1/2006
 
Title: New Imaging Kit for Assessment of Estrogen Receptors with Single Photon Emission Computed Tomography
Funding Source: US Army Breast Cancer Concept Grant
Role: Collaborator
Principal Investigator: Kim, Edmund E
Duration: 9/1/2004 - 8/1/2005
 
Title: Biokinetics of MicellarPaclitaxel Formulation
Funding Source: Samyang Company
Role: Principal Investigator
Duration: 9/1/2004 - 8/1/2005
 
Title: Local regional chemotherapy and radiotherapy using in situ hydrogel
Funding Source: Cell>Point Biotechnology Company
Role: Principal Investigator
Duration: 12/1/2003 - 12/1/2008
 
Title: CT and MRI Functional Agents Development and Evaluation
Funding Source: VeriMed Research Company
Role: Principal Investigator
Duration: 5/31/2002 - 5/31/2005
 
Title: Automation synthesis of PET tracers
Funding Source: Ho Kong Molecular Imaging Tech, Inc
Role: Principal Investigator
Duration: 10/1/2001 - 10/1/2002
 
Title: MR Assessment of Antiangiogenic Therapy
Funding Source: NIH-NCI Project 4 of U54 grant
Role: Collaborator
Principal Investigator: Abbruzzese, JL
Duration: 7/1/2001 - 12/1/2006
 
Title: Molecular Imaging with 99mTc-Peptide Conjugates
Funding Source: Daiichi Radioisotope Laboratories, Ltd
Role: Principal Investigator
Duration: 7/1/2001 - 7/1/2003
 
Title: PET Tracers in Oncology
Funding Source: Medics Japan, Ichibancho
Role: Principal Investigator
Duration: 5/15/2001 - 5/15/2003
 
Title: 99mTc-Ethylenedicysteine (EC)-drug Conjugates for Tissue Specific Disease Imaging
Funding Source: Cell>Point Biotechnology Company
Role: Principal Investigator
Duration: 5/2001 - 5/2016
 
Title: Hypoxia Imaging-guided IMRT
Funding Source: NIH-NCI R01
Role: Collaborator
Principal Investigator: Chao, Clifford KS
Duration: 3/1/2001 - 2/1/2005
 
Title: 99mTc-EC-Endostatin: Imaging, Response and Prognosis
Funding Source: Entremed, Inc
Role: Principal Investigator
Duration: 6/1/2000 - 5/31/2001
 
Title: Evaluation of autosynthetic device for radiochemistry
Funding Source: Anzai Medical Company
Role: Principal Investigator
Duration: 4/1/1997 - 4/1/2004

Last updated: 6/23/2014