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Dragan Mirkovic, Ph.D.

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
1400 Pressler Street
Unit Number: 1420
Houston, TX 77030-3722
Phone: 713-563-2643
Fax: 713-563-2545

Education & Training

Degree-Granting Education

1993 State University of New York at Stony Brook, Stony Brook, NY, PHD, Applied Mathematics
1990 University of Zagreb, Zagreb, Croatia, MS, Nuclear Engineering
1983 University of Zagreb, Zagreb, Croatia, BS, Nuclear Engineering

Experience/Service

Academic Appointments

Associate Member, The University of Texas Graduate School of Biomedical Sciences, Houston, TX, 4/2006-present
Assistant Professor, Dept. of Computer Science, University of Houston, Houston, TX, 9/2003-7/2005
Research Faculty, Dept. of Computer Science, University of Houston, Houston, TX, 9/1998-8/2003
Assistant Professor, Department of Mathematics, Iowa State University, Ames, IA, 8/1994-5/1999
Postdoctoral Research Associate, Applied Mathematics and Statistics, State University of New York at Stony Brook, Stony Brook, NY, 9/1993-8/1994
Research/Teaching Assistant, Applied Mathematics and Statistics, State University of New York at Stony Brook, Stony Brook, NY, 9/1990-8/1993
Visiting Scientist, Nuclear Energy, Brookhaven National Laboratory, Upton, NY, 4/1989-8/1990
Research Associate, Nuclear Energy, University of Zagreb, Zagreb, Croatia, 1/1984-6/1990

Honors and Awards

1990-1993 Research Fellowship (Selective), State University of New York Stony Brook
1989-1990 IAEA Fellowship, Brookhaven National Laboratory

Selected Publications

Peer-Reviewed Original Research Articles

1. Rechner LA, Eley JG, Howell RM, Zhang R, Mirkovic D, Newhauser WD. Risk-optimized proton therapy to minimize radiogenic second cancers. Phys Med Biol 60(10). e-Pub 4/2015. PMID: 25919133.
2. Zhang R, Mirkovic D, Newhauser WD. Visualization of risk of radiogenic second cancer in the organs and tissues of the human body. Radiat Oncol 10(1). e-Pub 4/2015. PMID: 25927490.
3. Huang JY, Kerns JR, Nute JL, Liu X, Balter PA, Stingo FC, Followill DS, Mirkovic D, Howell RM, Kry SF. An evaluation of three commercially available metal artifact reduction methods for CT imaging. Phys Med Biol 60(3):1047-67, 2/7/2015. e-Pub 1/14/2015. PMCID: PMC4311882.
4. Shao Y, Sun X, Lou K, Zhu XR, Mirkovic D, Poenisch F, Grosshans D. In-beam PET imaging for on-line adaptive proton therapy: An initial phantom study. Phys Med Biol 59(13):3373-88, 7/2014. e-Pub 5/2014. PMID: 24874943.
5. Huang JY, Eklund D, Childress NL, Howell RM, Mirkovic D, Followill DS, Kry SF. Investigation of various energy deposition kernel refinements for the convolution superposition method. Med Phys 40(12):121721, 12/2013. PMCID: PMC3856653.
6. Perles LA, Mirkovic D, Anand A, Titt U, Mohan R. LET dependence of the response of EBT2 films in proton dosimetry modeled as a bimolecular chemical reaction. Phys Med Biol 58(23):8477-91, 12/2013. e-Pub 11/2013. PMID: 24240474.
7. Newhauser WD, Rechner L, Mirkovic D, Yepes P, Koch NC, Titt U, Fontenot JD, Zhang R. Benchmark measurements and simulations of dose perturbations due to metallic spheres in proton beams. Radiat Meas 58:37-44, 11/1/2013. PMCID: PMC4136527.
8. Zhang R, Fontenot JD, Mirkovic D, Hendricks JS, Newhauser WD. ADVANTAGES OF MCNPX-BASED LATTICE TALLY OVER MESH TALLY IN HIGH-SPEED MONTE CARLO DOSE RECONSTRUCTION FOR PROTON RADIOTHERAPY. Nucl Technol 183(1):101-106, 7/2013. PMCID: PMC4244884.
9. Robertson D, Mirkovic D, Sahoo N, Beddar S. Quenching correction for volumetric scintillation dosimetry of proton beams. Phys Med Biol 58(2):261-73, 1/21/2013. e-Pub 12/21/2012. PMCID: PMC3849813.
10. Wang LL, Perles LA, Archambault L, Sahoo N, Mirkovic D, Beddar S. Determination of the quenching correction factors for plastic scintillation detectors in therapeutic high-energy proton beams. Phys Med Biol 57(23):7767-81, 12/2012. e-Pub 11/2012. PMID: 23128412.
11. Perles LA, Mirkovic D, Sawakuchi GO, Titt U. Monte Carlo investigation of rebinning material density distributions of lung parenchyma phantoms in proton therapy. Nuclear Technology 175(1):22-26, 6/2011.
12. Yepes PP, Mirkovic D, Taddei PJ. A GPU implementation of a track-repeating algorithm for proton radiotherapy dose calculations. Phys Med Biol 55(23):7107-20, 12/7/2010. e-Pub 11/12/2010. PMCID: PMC3001323.
13. Titt U, Mirkovic D, Sawakuchi GO, Perles LA, Newhauser WD, Taddei PJ, Mohan R. Adjustment of the lateral and longitudinal size of scanned proton beam spots using a pre-absorber to optimize penumbrae and delivery efficiency. Phys Med Biol 55(23):7097-106, 12/7/2010. e-Pub 11/12/2010. PMCID: PMC3001334.
14. Yepes PP, Brannan T, Huang J, Mirkovic D, Newhauser WD, Taddei PJ, Titt U. Application of a Fast Proton Dose Calculation Algorithm to a Thorax Geometry. Radiat Meas 45(10):1367-1368, 12/1/2010. PMCID: PMC3085469.
15. Taddei PJ, Mahajan A, Mirkovic D, Zhang R, Giebeler A, Kornguth D, Harvey M, Woo S, Newhauser WD. Predicted risks of second malignant neoplasm incidence and mortality due to secondary neutrons in a girl and boy receiving proton craniospinal irradiation. Phys Med Biol 55(23):7067-80, 12/7/2010. e-Pub 11/12/2010. PMCID: PMC3001324.
16. Taddei PJ, Howell RM, Krishnan S, Scarboro SB, Mirkovic D, Newhauser WD. Risk of second malignant neoplasm following proton versus intensity-modulated photon radiotherapies for hepatocellular carcinoma. Phys Med Biol 55(23):7055-65, 12/7/2010. e-Pub 11/12/2010. PMCID: PMC3001302.
17. Sawakuchi GO, Mirkovic D, Perles LA, Sahoo N, Zhu XR, Ciangaru G, Suzuki K, Gillin MT, Mohan R, Titt U. An MCNPX Monte Carlo model of a discrete spot scanning proton beam therapy nozzle. Med Phys 37(9):4960-70, 9/2010. PMCID: PMC2941520.
18. Sawakuchi GO, Titt U, Mirkovic D, Ciangaru G, Zhu XR, Sahoo N, Gillin MT, Mohan R. Monte Carlo investigation of the low-dose envelope from scanned proton pencil beams. Phys Med Biol 55(3):711-721, 2/2010. e-Pub 1/2010. PMID: 20071752.
19. Fontenot JD, Taddei P, Zheng Y, Mirkovic D, Newhauser WD. Ambient Dose Equivalent Versus Effective Dose for Quantifying Stray Radiation Exposures to a Patient Receiving Proton Therapy for Prostate Cancer. Nucl Technol 168(1):173-177, 10/1/2009. PMCID: PMC2938795.
20. Taddei PJ, Mirkovic D, Fontenot JD, Giebeler A, Zheng Y, Titt U, Woo S, Newhauser WD. Reducing Stray Radiation Dose for a Pediatric Patient Receiving Proton Craniospinal Irradiation. Nucl Technol 168(1):108-112, 10/1/2009. PMCID: PMC2943394.
21. Taddei PJ, Mirkovic D, Fontenot JD, Giebeler A, Zheng Y, Kornguth D, Mohan R, Newhauser WD. Stray radiation dose and second cancer risk for a pediatric patient receiving craniospinal irradiation with proton beams. Phys Med Biol 54(8):2259-2275, 4/21/2009. e-Pub 3/20/2009. PMCID: PMC4142507.
22. Newhauser WD, Fontenot JD, Mahajan A, Kornguth D, Stovall M, Zheng Y, Taddei PJ, Mirkovic D, Mohan R, Cox JD, Woo S. The risk of developing a second cancer after receiving craniospinal proton irradiation. Phys Med Biol 54(8):2277-2291, 4/21/2009. e-Pub 3/20/2009. PMCID: PMC4144016.
23. Newhauser WD, Fontenot JD, Taddei PJ, Mirkovic D, Giebeler A, Zhang R, Mahajan A, Kornguth D, Stovall M, Yepes P, Woo S, Mohan R. Contemporary Proton Therapy Systems Adequately Protect Patients from Exposure to Stray Radiation. AIP Conf Proc 1099(1):450-455, 3/10/2009. PMCID: PMC2939014.
24. Taddei PJ, Krishnan S, Mirkovic D, Yepes P, Newhauser WD. Effective Dose from Stray Radiation for a Patient Receiving Proton Therapy for Liver Cancer. AIP Conf Proc 1099:445-449, 3/10/2009. PMCID: PMC2943390.
25. Ezhil M, Vedam S, Balter P, Choi B, Mirkovic D, Starkschall G, Chang JY. Determination of patient-specific internal gross tumor volumes for lung cancer using four-dimensional computed tomography. Radiat Oncol 4:4, 2009. e-Pub 1/27/2009. PMCID: PMC2645420.
26. Sawakuchi GO, Titt U, Mirkovic D, Mohan R. Density heterogeneities and the influence of multiple Coulomb and nuclear scatterings on the Bragg peak distal edge of proton therapy beams. Phys Med Biol 53(17):4605-19, 9/2008. e-Pub 8/2008. PMID: 18678928.
27. Newhauser WD, Giebeler A, Langen KM, Mirkovic D, Mohan R. Can megavoltage computed tomography reduce proton range uncertainties in treatment plans for patients with large metal implants? Phys Med Biol 53(9):2327-44, 5/7/2008. e-Pub 4/17/2008. PMCID: PMC4120878.
28. Taddei PJ, Fontenot JD, Zheng Y, Mirkovic D, Lee AK, Titt U, Newhauser WD. Reducing stray radiation dose to patients receiving passively scattered proton radiotherapy for prostate cancer. Phys Med Biol 53(8):2131-47, 4/21/2008. e-Pub 3/27/2008. PMCID: PMC4144020.
29. Fontenot J, Taddei P, Zheng Y, Mirkovic D, Jordan T, Newhauser W. Equivalent dose and effective dose from stray radiation during passively scattered proton radiotherapy for prostate cancer. Phys Med Biol 53(6):1677-88, 3/2008. e-Pub 2/2008. PMID: 18367796.
30. Kurzak J, Mirkovic D, Pettitt BM, Johnsson SL. Automatic Generation of FFT for Translations of Multipole Expansions in Spherical Harmonics. Int J High Perform Comput Appl 22(2):219-230, 1/1/2008. PMCID: PMC2744990.
31. Zheng Y, Fontenot J, Taddei P, Mirkovic D, Newhauser W. Monte Carlo simulations of neutron spectral fluence, radiation weighting factor and ambient dose equivalent for a passively scattered proton therapy unit. Phys Med Biol 53(1):187-201, 1/2008. e-Pub 12/2007. PMID: 18182696.
32. Canic S, Tambaca J, Mikelic A, Hartley CJ, Mirkovic D, Chavez J, Rosenstrauch D. Blood flow through axially symmetric sections of compliant vessels: new effective closed models. Conf Proc IEEE Eng Med Biol Soc 5:3696-3699, 2007. PMID: 17271096.
33. Yang XF, Mirkovic D, Zhang S, Zhang QE, Yan Y, Xiong Z, Yang F, Chen IH, Li L, Wang H. Processing sites are different in the generation of HLA-A2.1-restricted, T cell reactive tumor antigen epitopes and viral epitopes. International Journal Immunopathology Pharmacology 19/4:853-70, 10/2006. PMID: 17166407.
34. Yang Y, Yang F, Xiong Z, Yan Y, Wang X, Nishino M, Mirkovic D, Nguyen J, Wang H, Yang X. An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity. Oncogene 24:4778-4788, 2005.
35. Canic S, Ravi-Chandar K, Krajcer Z, Mirkovic D, Lapin S. Mathematical Model analysis of Wallstent and Aneurx: dynamic responses of bare-metal endoprosthesis compared with those of stent-graft. Tex Heart Inst J 32/4(4):502-6, 2005. PMCID: PMC1351820.
36. Mirkovic D, Johnson SL. Automatic performance tuning for fast fourier transforms. International Journal of High Performance Computing Applications 18/1:47-64, 2004.
37. Mirkovic D, Johnson SL. CODELAB: A developers' tool for efficient code generation and optimization. Lecture Notes in Computer Science 2657/4:729-738, 2003.
38. Canic S, Mirkovic D. A hyperbolic system of conservation laws arising in modeling endovascular treatment of abdominal aortic aneurysm. Hyperbolic Problems: Theory, numerics, applications 141:227-236, 2001.
39. Mirkovic D, Johnsson SL. Automatic Performance Tuning in UHFFT Library. Lecture Notes in Computer Science 2073/1:71-80, 2001.
40. Canic S, Mirkovic D. Numericdal study of riemann problems for the two-dimensional unsteady transonic small disturbance equation. SIAM Journal on Applied Mathematics 58:1365-1393, 1998.
41. Mirkovic D, Diamond DJ. Effect of flusing of boron during a boiling water reactor anticipated transsient without scram. Nuclear Technology 95:162-174, 1991.
42. Mirkovic D, Diamond DJ, Hsu CJ, Fitzpatrick R. The potential for catastrophic fuel damage during beyond-design-basis over pressurization accidents in a boiling water reactor. Nuclear Technology 93:158-165, 1991.
43. Mirkovic D, Diamond DJ. Boron Flusing during BWR ATWS. Trans of American Nuclear Society 61:222-223, 1990.
44. Diamond DJ, Hsu C-J, Fitzpatrick, R, Mirkovic D. Reactivity accidents with the potential for catastrophic fuel damage. Nuclear Safety 31:311-317, 1990.

Editorials

1. Rumbaut RE, Mirkovic D. Magnetic therapy for edema in inflammation: a physiological assessment. Am J Physiol Heart Circ Physiol 294(1):19-20, 1/2008. e-Pub 11/2007. PMID: 18032520.

Abstracts

1. Peeler C, Taleei R, Guan F, Bronk L, Grosshans D, Mirkovic D, Titt U, Mohan R. Application of the Repair-Misrepair-Fixation RBE Model to Describe the Results of High Resolution Proton Irradiation Cell Survival Experiments. Medical Physics 41(6), 6/2014.
2. Titt U, Mirkovic D, Liu A, Anand A, Perles L, Ciangaru G, Mohan R. Commissioning of the MC2 Monte Carlo Dose Computation Engine. Medical Physics 41(6), 6/2014.
3. Huang J, Kerns J, Nute J, Liu X, Stingo F, Followill D, Mirkovic D, Howell R, Kry S. Evaluation of Three Commercial Metal Artifact Reduction Methods for CT Simulations in Radiation Therapy Treatment Planning. Medical Physics 41(6), 6/2014.
4. Mirkovic D, Yepes P, Titt U, Mohan R. Fast Four Dimensional Monte Carlo Dose Computations for Proton Therapy of Lung Cancer. Medical Physics 41(6):535, 6/2014.
5. Bronk L, Guan F, Kerr M, Dinh J, Titt U, Mirkovic D, Lin S, Mohan R, Grosshans D. High-Throughput Mapping of Proton Biologic Effect. Medical Physics 41(6):505, 6/2014.
6. Randeniya S, Mirkovic D, Titt U, Guan F, Mohan R. Importance of Energy Dependent Protons Per MU Calibration Factors in IMPT Dose Calculations Using Monte Carlo Technique. Medical Physics 41(6), 6/2014.
7. Taleei R, Titt U, Peeler C, Guan F, Mirkovic D, Grosshans D, Mohan R. Modeling Physics Properties and Biologic Effects Induced by Proton and Helium Ions. Medical Physics 41(6):534, 6/2014.
8. Guan F, Bronk L, Kerr M, Titt U, Taleei R, Mirkovic D, Zhu X, Grosshans D, Mohan R. The Effect of Particle Tracking Step Size Limit On Monte Carlo-Computed LET Spectrum of Therapeutic Proton Beams. Medical Physics 41(6):534, 6/2014.
9. Peeler C, Mirkovic D, Perles L, Titt U, Grosshans D, Mohan R. Comparison of Results for RBE‐Weighted Dose From Two RBE Models for Proton Therapy Treatment Plans. Medical Physics 40(6):552, 6/2013.
10. Huang J, Eklund D, Childress N, Howell R, Mirkovic D, Kry S. Dosimetric Impact of Implementing Kernel Hardening and Material‐Specific Kernels in the Convolution/Superposition Method. Medical Physics 40(6):333, 6/2013.
11. Taddei PJ, Khater N, Youssef B, Jalbout W, Howell RM, Mahajan A, Zhang R, Mirkovic D, Giebeler A, Geara FB, Newhauser WD. Equivalent Dose in Children Receiving Craniospinal Irradiation with Photons in a Developing Country Or with Protons in a Developed Country. Medical Physics 40(6):267, 6/2013.
12. Guan F, Mohan R, Dinh J, Kerr M, Perles L, Mirkovic D, Titt U, Zhu X, Gillin M, Meyn R, Lin S, Grosshans D. Experimental Design and Preliminary Results for High‐Resolution and High‐Throughput In‐Vitro Measurements of Proton RBE. Medical Physics 40(6):552, 6/2013.
13. Shao Y, Sun X, Lou K, Zhu X, Mirkovic D, Poenisch F, Grosshans D. In‐Beam PET Imaging with Depth‐Of‐Interaction Measurement for Accurate Proton Beam‐Range Verification. Medical Physics 40(6):503, 6/2013.
14. Perles LA, Titt U, Mirkovic D, Mohan R. Modeling the Cell Inactivation Process for High LET Particles by Using the Law of Mass Action. Medical Physics 40(6):272, 6/2013.
15. Titt U, Guan F, Mirkovic D, Mohan R. On the Out‐Of‐Field‐Doses Caused by Secondary Particles From Light Ion Beams in Charged Particle Therapy. Medical Physics 40(6):328, 6/2013.
16. Titt U, Liu A, Mirkovic D. Runtime Optimization for the Automatic Monte Carlo Dose Computation System MC2. Medical Physics 40(6):326, 6/2013.
17. Titt U, Mirkovic D, Mohan R. Three‐Dimensional Energy Fluence Estimates for Future Treatment Planning Systems. Medical Physics 40(6):88, 6/2013.
18. Mirkovic D, Titt U, Peeler C, Perles L, Liao Z, Mohan R. Variable RBE and Incidence of Radiation Pneumonitis in Lung Patients Treated with Proton Therapy. Medical Physics 40(6):455, 6/2013.
19. Mirkovic, D, Peeler, C, Grosshans, D, Titt, U, Mohan, R. Is Constant RBE Accurate Enough for Determination of Biological Effects in Proton Therapy?. International Journal of Radiation Oncology Biology Physics 84(3), 11/2012.
20. Robertson D, Mirkovic D, Beddar S. A Quenching Correction Method for Volumetric Scintillation Dosimetry of Proton Beams. Medical Physics 39(6):3886, 6/2012.
21. Titt U, Mirkovic D, Liu A, Mohan R. Automatic Monte Carlo Dose Calculations of Proton Treatment Plans. Medical Physics 39(6):3805, 6/2012.
22. Peeler C, Mirkovic D, Grosshans D, Titt U, Mohan R. Correlating Areas of Radiation Toxicity with Relative Biological Effectiveness-Weighted Dose Distributions in Proton Radiotherapy. Medical Physics 39(6):3994, 6/2012.
23. Perles L, Mirkovic D, Anand A, Titt U, Mohan R. Dose Response of EBT2 Film Modeled as a Bimolecular Reaction. Medical Physics 39(6):4009, 6/2012.
24. Sell M, Titt U, Perles L, Mirkovic D, Mohan R, Bangert M, Oelfke U. Evaluation of Analytical Proton Dose Predictions with a Lung--Like Plastic Phantom. Medical Physics 39(6):3956, 6/2012.
25. Titt U, Mirkovic D, Perles L, Sell M, Peeler C, Liu A, Mohan R. Monte Carlo Phase Space Production to Model Magnetically Scanned Proton Beams for IMPT. Medical Physics 39(6):3814, 6/2012.
26. Mirkovic D, Titt U, Mohan R. Potential Clinical Impact of Dosimetric Uncertainties in Proton Therapy. Medical Physics 39(6):3816, 6/2012.
27. Perles LA, Ibbott G, Blatnica A, Mirkovic D, Titt U, Gillin M, Mohan R. 3D Proton Dose Distributions in An Anthropomorphic Lung Phantom, Comparing Monte Carlo, Film, and TLD Measurements. Medical Physics 38(6):3780, 6/2011.
28. Mirkovic D, Titt U, Mohan R. Accuracy of Patient Dose Calculation in Proton Therapy of Lung Cancer: A Comparison of Monte Carlo and Pencil Beam Computations. Medical Physics 38(6):3642, 6/2011.
29. Wang L, Perles L, Archambault L, Sahoo N, Beddar S, Mirkovic D. Application of a Plastic Scintillation Detector in Measuring Depth-Dose Curves for Passive-Scattering Proton Beams. Medical Physics 38(6):3366, 6/2011.
30. Taddei PJ, Jalbout WT, Geara FB, Mirkovic D, Howell RM, Zhang R, Giebeler A, Mahajan A, Newhauser WD. Comparison of the Risk of Second Malignant Neoplasm in a Developed Country Versus a Developing Country for a 13-Year-Old Girl Receiving Craniospinal Irradiation. Medical Physics 38(6):3736, 6/2011.
31. Mohan R, Mirkovic D, Titt U, Song X, Zhu XR, Gillin MT. Experimental Assessment of the Accuracy of a Semi-Empirical Model and a Monte Carlo System for Proton Dose Calculations for Highly Inhomogeneous Media. Medical Physics 38(6):3648, 6/2011.
32. Faught A, Mirkovic D. Implementation of a One Dimensional Analytical Model for Calculating Three Dimensional Linear Energy Transfer in Proton Radiotherapy. Medical Physics 38(6):3659, 6/2011.
33. Titt U, Mirkovic D, Anand A, Perles LA, Sawakuchi GO, Mohan R. On the Dependence of Scanned Proton Beam Dose Output Factors On the Field Size and the Accuracy of the Lateral Dose Profiles. Medical physics 38(6):3382, 6/2011.
34. Yepes P, Mirkovic D, Keyes R, Panchal P. Online Monte-Carlo-Accurate Real-Time Proton Dose Calculator. Medical Physics 38(6):3650, 6/2011.
35. Randeniya SD, D Mirkovic D, Kry S, Titt U, Newhauser WD, Howell RM. Patient Specific Out-Of-Field Dose Calculation Tool for 6MV and 18MV: Development and Validation. Medical Physics 38(6):3736, 6/2011.
36. Robertson D, Mirkovic D, Mohan R, Beddar S. Voxelized Quenching Correction for Proton Pencil Beams in a Liquid Scintillator Detector. Medical Physics 38(6):3816, 6/2011.
37. Bednarz B, Mirkovic D, Titt U, Paganetti H. A Joint Research Investigation Comparing MCNPX and Geant4 Monte Carlo Codes to Reduce the Range Uncertainties in Proton Therapy. Med. Phys. 37(6):3286, 6/2010.
38. Titt U, Mirkovic D, Sawakuchi G, Perles L, Newhauser W, Taddei P, Mohan R. Adjustment of Lateral and Longitudinal Size of Scanned Proton‐Beam Spots Using a Pre‐Absorber. Med. Phys. 37(6):3353, 6/2010.
39. Randeniya S, Mirkovic D, Kry S, Titt U, Newhauser W, Howell R. Automated Photon Monte Carlo Linear Accelerator Model for Calculating In‐Field and Out‐Of‐Field Dose. Med. Phys. 37(6):3281, 6/2010.
40. Mirkovic D, Titt U, Sawakuchi G, Mohan R. Biological Effects of Variable RBE in Different Proton Therapy Delivery Modalities. Med. Phys. 37(6):3365, 6/2010.
41. Rechner L, Mirkovic D, Fontenot J, Newhauser W. Modeling Multiple Coulomb Scattering in Therapeutic Proton Beams: A Comparison of Two Algorithms. Med. Phys. 37(6):3282, 6/2010.
42. Perles L, Sawakuchi G, Mirkovic D, Mohan R, Titt U. Monte Carlo Investigation and Measurements of Distal Edge Degradation in Lung Phantoms with Therapeutic Proton Beams. Med. Phys. 37(6):3145, 6/2010.
43. Mirkovic D, Titt U, Sawakuchi GO, Zhang X, Li Y, Mohan R. Monte Carlo computation of the effective dose in scanning beam proton therapy. Med. Phys. 36(6):2612, 6/2009.
44. Harvey MC, Taddei PJ, Mirkovic D, Newhauser WD. Nuclear Model Evaluation of Uncertainties in Therapeutic Absorbed Dose and Secondary Neutron Production in Proton Radiotherapy using MCNPX. Medical Physics 36(6):2702, 6/2009.
45. Peng Y, Balter P, mirkovic D, Vedam S. Real-time characterization of respiratory motion regularity during radiation therapy. Med. Phys. 36(6):2503, 6/2009.
46. Yepes P, Newhauser WD, Randeniya S, Taddei PJ, mirkovic D. Reducing the Simulation Time of a Prostate Cancer Clinical Setup by Two Orders of Magnitude. Med. Phys 36(6):2622, 6/2009.
47. Taddei PJ, Mirkovic D, Fontenot JD, Zheng Y, Kornguth D, Mohan R, Newhauser WD. Second cancer risk from secondary neutrons for a boy who received proton craniospinal irradiation. Med. Phys. 36(6):2628, 6/2009.
48. Sawakuch G, Titt U, Ciangaru G, Mirkovic D, Zhu X, Mohan R. The Causes of the Lateral Envelop of Low Doses in Scanning Proton Beamlets. Medical Physics 36(6):2620, 6/2009.
49. Sawakuchi G, Titt U, Mirkovic D, Zhu X, Sahoo N, Bues M, Ciangaru G, Poenisch F, Suzuki K, Arjomandy B, Gillin M, Mohan R. Validation of An MCNPX Monte Carlo Model of a Discrete-Spot Scanning Beam Nozzle and Evaluation of the Beamlet Lateral Envelope of Low Doses. Medical Physics 36(6):2782-2783, 6/2009.
50. Titt U, Zhang X, Li Y, Mirkovic D, Sawakuchi G, Mohan R. Monte Carlo Study of Distal Edge Degradation in Proton Therapy Due to Heterogeneities. Proof of Principle with a Case Study. Medical Physics 35(6), 6/2008.
51. Taddei PJ, Mirkovic D, Fontenot JD, Giebeler A, Zheng Y, Titt U, Woo S, Newhauser WD. Reducing Stray Radiation Dose for a Pediatric Patient Receiving Craniospinal Irradiation with Protons. Medical Physics 35(6), 6/2008.
52. Mirkovic D, Vedam S, Chang JY. Volumetric Analysis of Moving Structures in Radiation Treatment Planning. Medical Physics 35(6), 6/2008.
53. Newhauser W, Fontenot J, Zheng Y, Taddei P, Mirkovic D, Titt U, Zhu X, Sahoo N, Schaffner B, Langenegger A, Koch N, Zhang X, Mohan R. A Monte-Carlo Based Dose Engine for Proton Radiotherapy Treatment Planning. Medical Physics 34(6):2406, 6/2007.
54. Taddei P, Fontenot J, Zheng Y, Mirkovic D, Titt U, Newhauser W. Monte Carlo Investigation of Local Shielding to Reduce Stray Radiation Doses to Patients Receiving Proton Therapy. Medical Physics 34(6):2471, 6/2007.
55. Kang Y, Mirkovic D, Dong L. Sensitivity of Proton and Photon Plans to the Intra- and Inter-Fractional Changes in Patient's Anatomy. Medical Physics 34(6):2390, 6/2007.
 

Other

1. Nuclear Regulatory Comission Report. Mirkovic D, Diamond, DJ (1990) Boron Flushing During BWR Anticipated Transient Without Scram, Technical report, U.S. Nuclear Regulatory Commission, NUREG/CR-5573.
2. Conference proceedings.

Mirkovic D. N-Dimensional Finite Element Package. Proceedings of the High Performance Computing Conference, April 1996, New Orleans, LA, pp. 324-329, 1996.

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3. Conference proceedings. Mirkovic D, Mahasoom R, Johnsson SL. An Adaptive Software Library for Fast Fourier Transforms. Proceedings of the 2000 International Conference on Supercomputing, Santa Fe, NM , pp. 215-224, 2000.
4. Conference proceedings.

Mirkovic D, Johnsson SL. Automatic Performance Tuning in UHFFT Library. In proceedings of the 2001 International Conference on Computational Science, ICCS 2001, May 2001, San Francisco, Lecture Notes in Computer Science 2073, Vol. 1, pp. 71-80, 2001.

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5. Conference proceedings.

Canic S, Tambaca J, Mikelic A, Hartley C J, Mirkovic D, Chavez J, Rosenstrauch D. Blood flow through axially symmetric sections of compliant vessels: new effective closed models, Proceedings of the 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, September 1-5, 2004.

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6. Conference proceedings.

Ali A, Johnsson L, Mirkovic D. Empirical Auto-tuning Code Generator for FFT and Trignometric Transforms ODES: 5th Workshop on Optimizations for DSP and Embedded Systems, in conjunction with International Symposium on Code Generation and Optimization (CGO), 2007.

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Grant & Contract Support

Title: Understanding Biological and Physical Factors Affecting Response to Proton Therapy to Improve its Clinical Effectiveness
Funding Source: Cancer Prevention & Research Institute of Texas (CPRIT)
Role: Principal Investigator
Duration: 3/1/2016 - 2/28/2019
 
Title: Improving the Clinical Effectiveness and Understanding of the Biophysical Basis of Proton Therapy: Core B - Clinical & Research Support at MDACC
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Radhe Mohan/Thomas DeLaney
Duration: 9/1/2015 - 8/31/2016
 
Title: Improving the Clinical Effectiveness and Understanding of the Biophysical Basis of Proton Therapy: Project 3 - Assessing accuracy of proton therapy and understanding the impact of physical and biophysical factors on its outcomes
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Radhe Mohan/Thomas DeLaney
Duration: 9/1/2015 - 8/31/2016
 
Title: Improving the Clinical Effectiveness and Understanding of the Biophysical Basis of Proton Therapy: Project 4 - Improving outcomes by optimally exploiting physical and biological characteristics of protons
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Radhe Mohan/Thomas DeLaney
Duration: 9/1/2015 - 8/31/2016
 
Title: Moving proton therapy towards its full potential by using fast Monte Carlo techniquies
Funding Source: Cancer Prevention & Research Institute of Texas (CPRIT)
Role: Principal Investigator-MDACC
Principal Investigator: Yepes
Duration: 3/1/2015 - 2/28/2018
 
Title: Advancing Linear Energy Transfer Models for Biologically Optimized Proton Therapy
Funding Source: MDACC-IRG
Role: Co-Investigator
Principal Investigator: David Grosshans, MD, PhD
Duration: 2/15/2015 - 2/14/2016
 
Title: The future of particle therapy: Physics and biology of light ions
Funding Source: UTMDACC - The Center for Radiation Oncology Research
Role: Co-Investigator
Principal Investigator: Uwe Titt
Duration: 11/1/2014 - 10/31/2015
 
Title: Improving the clinical effectiveness and understanding of the biophysical basis - Project 3: Assessing accuracy of proton therapy and understanding the impact of physical and biophysical factors on its outcomes
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Radhe Mohan
Duration: 9/25/2014 - 8/31/2015
 
Title: Improving the clinical effectiveness and understanding of the biophysical basis - Project 4: Improving outcomes by optimally exploiting physical and biological characteristics of protons
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Radhe Mohan
Duration: 9/25/2014 - 8/31/2015
 
Title: Improving the clinical effectiveness and understanding of the biophysical basis - Core B: Clinical & Research Support at MDACC
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Mohan/DeLaney
Duration: 9/25/2014 - 8/31/2015
 
Title: Mapping Proton RBE Variability Using Automated Biology and Monte Carlo Techniques
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: David Grosshans, MD, PhD
Duration: 8/1/2014 - 7/31/2016
 
Title: Intensity Modulated Particle Therapy
Funding Source: Sister Institution Network Fund
Role: Co-Investigator
Duration: 2/1/2012 - 9/30/2014
 
Title: In-Situ PET Imaging for Adaptive Proton Therapy
Funding Source: Cancer Prevention & Research Institute of Texas (CPRIT)
Role: Collaborator
Principal Investigator: Yiping Shao
Duration: 11/2/2011 - 5/31/2015
 
Title: Optimizing Proton Therapy - Core B: Clinical and Computational Support
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Thomas DeLaney
Duration: 9/25/2008 - 7/31/2014
 
Title: Optimizing Proton Therapy - Core C: Statistics, Data Exchange, Management and Support
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Thomas DeLaney
Duration: 9/25/2008 - 7/31/2014
 
Title: Optimizing Proton Therapy - Core C: Statistics, Data Exchange, Management and Support
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Thomas DeLaney
Duration: 9/25/2008 - 7/31/2014
 
Title: Optimizing Proton Therapy - Core B: Clinical and Computational Support
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Thomas DeLaney
Duration: 9/25/2008 - 7/31/2014
 
Title: FFT library Development
Funding Source: Intel Corporation
Role: Co-Investigator
Principal Investigator: Lennart Johnsson
Duration: 5/1/2004 - 5/1/2006
 
Title: Los Alamos Computer Science Institute
Funding Source: Department of Energy (DOE)
Role: Investigator
Principal Investigator: Lennart Johnsson
Duration: 10/1/1999 - 9/30/2002
 
Title: Grid Application Development Software
Funding Source: National Science Foundation (NSF)
Role: Investigator
Principal Investigator: Lennart Johnsson
Duration: 10/1/1999 - 9/30/2002
 
Title: Scalable Scientific Software Libraries
Funding Source: National Science Foundation (NSF)
Role: Senior Investigator
Principal Investigator: Lennart Johnsson
Duration: 10/1/1997 - 9/30/2002
 
Title: Nonlinear Filtering Approaches to Multitarget Tracking
Funding Source: ONR (Office of Naval Research
Role: Co-Investigator
Principal Investigator: Wolfgang Kliemann, PhD
Duration: 9/30/1996 - 9/30/1999
 
Title: ISU Startup Grant
Funding Source: Iowa State University
Role: Principal Investigator
Duration: 9/1/1996 - 8/31/1997

Last updated: 8/25/2015