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Fernanda Staquicini, PhD

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Genitourinary Medical Oncology - Research, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

2004 Federal University of Sao Paulo, Sao Paulo, Brazil, PHD, Immunology
2000 Federal University of Sao Paulo, Sao Paulo, Brazil, BS, Biomedical Sciences

Postgraduate Training

2005-2011 Research Fellowship, The University of Texas MD Anderson Cancer Center, Houston, TX, Dr. Renata Pasqualini and Dr. Wadih Arap

Honors and Awards

2010 Ben F. Love Fellowship in Innovative Cancer Therapies, The University of Texas MD Anderson Cancer Center
2010 Trainee Excellence Award, The University of Texas MD Anderson Cancer Center
2000 V Premio Jovem Cientista Prof. Dr. Mario Mariano - Scholar-in-Training Award, University of Sao Paulo
2000 XIV Premio Pereira Barreto - Scholar-in-Training Award, Federal University of Sao Paulo

Selected Publications

Peer-Reviewed Original Research Articles
1. Guzman-Rojas L, Rangel R, Salameh A, Edwards JK, Dondossola E, Kim YG, Saghatelian A, Giordano RJ, Kolonin MG, Staquicini FI, Koivunen E, Sidman RL, Arap W, Pasqualini R. Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment. Proc Natl Acad Sci U S A 109(5):1637-42, 1/2012. PMID: 22307623.
2. Staquicini FI, Cardó-Vila M, Kolonin MG, Trepel M, Edwards JK, Nunes DN, Sergeeva A, Efstathiou E, Sun J, Almeida NF, Tu SM, Botz GH, Wallace MJ, O'Connell DJ, Krajewski S, Gershenwald JE, Molldrem JJ, Flamm AL, Koivunen E, Pentz RD, Dias-Neto E, Setubal JC, Cahill DJ, Troncoso P, Do KA, Logothetis CJ, Sidman RL, Pasqualini R, Arap W. Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc Natl Acad Sci U S A 108(46):18637-42, 11/2011. PMID: 22049339.
3. Staquicini FI, Ozawa MG, Moya CA, Driessen WH, Barbu EM, Nishimori H, Soghomonyan S, Flores LG 2nd, Liang X, Paolillo V, Alauddin MM, Basilion JP, Furnari FB, Bogler O, Lang FF, Aldape KD, Fuller GN, Höök M, Gelovani JG, Sidman RL, Cavenee WK, Pasqualini R, Arap W. Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest 121(1):161-73, 1/2011. PMID: 21183793.
4. Souza GR, Staquicini FI, Christianson DR, Ozawa MG, Miller JH, Pasqualini R, Arap W. Combinatorial targeting and nanotechnology applications. Biomed Microdevices 12(4):597-606, 8/2010. PMID: 19669890.
5. Staquicini FI, Dias-Neto E, Li J, Snyder EY, Sidman RL, Pasqualini R, Arap W. Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells. Proc Natl Acad Sci U S A 106(8):2903-8, 2/2009. PMID: 19193855.
6. Staquicini FI, Tandle A, Libutti SK, Sun J, Zigler M, Bar-Eli M, Aliperti F, Pérez EC, Gershenwald JE, Mariano M, Pasqualini R, Arap W, Lopes JD.. A subset of host B lymphocytes controls melanoma metastasis through a melanoma cell adhesion molecule/MUC18-dependent interaction: evidence from mice and humans. Cancer Res 68(20):8419-28, 10/2008. PMID: 18922915.
7. Hajitou A, Lev DC, Hannay JA, Korchin B, Staquicini FI, Soghomonyan S, Alauddin MM, Benjamin RS, Pollock RE, Gelovani JG, Pasqualini R, Arap W. A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging. Proc Natl Acad Sci U S A 105(11):4471-6, 3/2008. PMID: 18337507.
8. Kolonin MG, Bover L, Sun J, Zurita AJ, Do KA, Lahdenranta J, Cardo-Vila M, Giordano RJ, Jaalouk DE, Ozawa MG, Moya CA, Souza GR, Staquicini FI, Kunyiasu A, Scudiero DA, Holbeck SL, Sausville EA, Arap W, Pasqualini R. Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries. Cancer Res 66(1):34-40, 1/2006. PMID: 16397212.
9. Souza GR, Christianson DR, Staquicini FI, Ozawa MG, Snyder EY, Sidman RL, Miller JH, Arap W, Pasqualini R. Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents. Proc Natl Acad Sci U S A 103(5):1215-20, 1/2006. PMID: 16434473.
10. Staquicini FI, Moreira CR, Nascimento FD, Tersariol IL, Nader HB, Dietrich CP, Lopes JD. Enzyme and integrin expression by high and low metastatic melanoma cell lines. Melanoma Res 13(1):11-8, 2/2003. PMID: 12569279.

Invited Articles
1. Staquicini FI, Sidman RL, Arap W, Pasqualini R. Phage display technology for stem cell delivery and systemic therapy. Adv Drug Deliv Rev 62(12):1213-6, 9/2010. PMID: 20932865.
2. Staquicini FI, Moeller BJ, Arap W, Pasqualini R. Combinatorial vascular targeting in translational medicine. Proteomics Clin Appl 4(6-7):626-32, 7/2010. PMID: 21137081.
3. Staquicini FI, Pasqualini R, Arap W. Ligand-directed profiling: applications to target drug discovery in cancer. Expert Opinion in Drug Discovery 4(1):51-9, 2009.

Abstracts
1. Staquicini FI, Moya CA, Ozawa MG, Driessen WHP, Kolonin MG, Nishimori H, Furnari FB, Bogler O, Lang FF, Fuller GN, Basilion JP, Aldape KD, Sidman RL, Cavenee WB, Pasqualini R, Arap W. In vivo functional selection and attributes of an iron-mimic peptide motif: regulation of the transferrin-transferrin receptor pathway. American Association of Cancer Research, 2010.
2. Staquicini FI, Dias-Neto E, Li J, Snyder EY, Sidman RL, Arap W, Pasqualini R. Discovery of a functional protein complex of netrin-4, laminin 1 chain and integrin alpha 6 beta 1 in mouse neural stem cells. Gordon Research Conference – Ventura, 2009.
3. Staquicini FI, Kolonin MG, Bover L, Sun J, Zurita AJ, Do KA, Lahdenranta J, Cardo-Vila M, Giordano RJ, Jaalouk DE, Ozawa MG, Moya CA, Souza GR, Kunyiasu A, Scudiero DA, Holbeck SL, Sausville EA, Arap W, Pasqualini R. Ligand-directed mapping of molecular targets in prostate cancer. American Association of Cancer Research, 2006.

Book Chapters
1. Ozawa MG, Staquicini FI, Sidman RL, Arap W, Pasqualini R. Targeting of central nervous system tumors–bridging the gap with phage display. In: CNS cancer, Models, Prognostic Factors and Targets. Chapter 32. Ed(s) E.G. Van Meir. Humana Press, Springer: New York, NY, 775-787, 2009.

Last updated: 2/19/2013