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H. Franklin Herlong, MD

Present Title & Affiliation

Primary Appointment

Professor, Department of Gastroenterology, Hepat,& Nutr, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd.
Unit Number: 1466
Houston, TX 77030
Room Number: Unit Number 1466
Phone: 713-794-5073
Fax: 713-745-4907

Education & Training

Degree-Granting Education

1974 Medical University of South Carolina, Charleston, SC, MD, Medical Doctorate
1970 Duke University, Durham, NC, BA, Bachelor of Arts

Postgraduate Training

6/1977-6/1979 Clinical Fellowship, Gastroenterology, The Johns Hopkins Hospital, Baltimore, MD
6/1975-6/1977 Clinical Residency, The Johns Hopkins Hospital, Baltimore, MD
6/1974-6/1975 Clinical Internship, Internal Medicine, The Johns Hopkins Hospital, Baltimore, MD

Board Certifications

6/1979 American Board of Internal Medicine

Professional Memberships

American Association for the Study of Liver Disease
Member, 1982-present
American Liver Foundation
Member, 1987-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Velamati PG, Herlong HF. Treatment of refractory ascites. Curr Treat Options Gastroenterol 9(6):530-7, 2006. PMID: 17081486.
2. Gebo KA, Herlong HF, Torbenson MS, Jenckes MW, Chander G, Ghanem KG, El-Kamary SS, Sulkowski M, Bass EB. Role of liver biopsy in management of chronic hepatitis C: a systematic review. Hepatology 36(5 Suppl 1):S161-72, 11/2002. PMID: 12407590.
3. Gebo KA, Chander G, Jenckes MW, Ghanem KG, Herlong HF, Torbenson MS, El-Kamary SS, Bass EB. Screening tests for hepatocellular carcinoma in patients with chronic hepatitis C: a systematic review. Hepatology 36(5 Suppl 1):S84-92, 11/2002. PMID: 12407580.
4. Chander G, Sulkowski MS, Jenckes MW, Torbenson MS, Herlong HF, Bass EB, Gebo KA. Treatment of chronic hepatitis C: a systematic review. Hepatology 36(5 Suppl 1):S135-44, 11/2002. PMID: 12407587.
5. Gebo KA, Jenckes MW, Chander G, Torbenson MS, Ghanem KG, Herlong HF, Sulkowski MS, El-Kamary SS, Harris KA, Guedelhoefer OC, Bass EB. Management of chronic hepatitis C. Evid Rep Technol Assess (Summ)(60):1-7, 6/2002. PMID: 12187570.
6. Bailey RW, Brengman ML, Fuh KC, Hamilton SR, Herlong HF, Bulkley GB. Hemodynamic pathogenesis of ischemic hepatic injury following cardiogenic shock/resuscitation. Shock 14(4):451-9, 10/2000. PMID: 11049109.
7. Ahrendt SA, Pitt HA, Kalloo AN, Venbrux AC, Klein AS, Herlong HF, Coleman J, Lillemoe KD, Cameron JL. Primary sclerosing cholangitis: resect, dilate, or transplant? Ann Surg 227(3):412-23, 3/1998. PMCID: PMC1191280.
8. Herlong HF. Approach to the patient with abnormal liver enzymes. Hosp Pract (Off Ed) 29(11):32-8, 11/1994. PMID: 7962234.
9. Lillemoe KD, Ahrendt GM, Yeo CJ, Herlong HF, Cameron JL. Surgery--still an "old boys' club"? Surgery 116(2):255-9; discussion 259-61, 8/1994. PMID: 8047993.
10. Mezey E, Caballería J, Mitchell MC, Parés A, Herlong HF, Rodés J. Effect of parenteral amino acid supplementation on short-term and long-term outcomes in severe alcoholic hepatitis: a randomized controlled trial. Hepatology 14(6):1090-6, 12/1991. PMID: 1959859.
11. Herlong HF. Laboratory tests of liver function. Trans Assoc Life Insur Med Dir Am 74:152-8, 1991. PMID: 1853522.
12. Herlong HF, Maddrey WC, Walser M. Branched-chain ketoacids in encephalopathy. Hepatology 12(6):1458-9, 12/1990. PMID: 2258167.
13. Felver ME, Mezey E, McGuire M, Mitchell MC, Herlong HF, Veech GA, Veech RL. Plasma tumor necrosis factor alpha predicts decreased long-term survival in severe alcoholic hepatitis. Alcohol Clin Exp Res 14(2):255-9, 4/1990. PMID: 2190492.
14. Rothstein JD, Herlong HF. Neurologic manifestations of hepatic disease. Neurol Clin 7(3):563-78, 8/1989. PMID: 2671636.
15. Carithers RL, Herlong HF, Diehl AM, Shaw EW, Combes B, Fallon HJ, Maddrey WC. Methylprednisolone therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial. Ann Intern Med 110(9):685-90, 5/1989. PMID: 2648927.
16. Burdick JF, Colombani PM, Pitt HA, Perler BA, Merritt WT, Crandall BC, Mitchell MC, Herlong HF, Williams GM. Overcoming early cyclosporine nephrotoxicity after liver transplantation. Transplant Proc 21(1 Pt 2):2236-7, 2/1989. PMID: 2652724.
17. Mezey E, Kolman CJ, Diehl AM, Mitchell MC, Herlong HF. Alcohol and dietary intake in the development of chronic pancreatitis and liver disease in alcoholism. Am J Clin Nutr 48(1):148-51, 7/1988. PMID: 3389321.
18. Cameron JL, Pitt HA, Zinner MJ, Herlong HF, Kaufman SL, Boitnott JK, Coleman J. Resection of hepatic duct bifurcation and transhepatic stenting for sclerosing cholangitis. Ann Surg 207(5):614-22, 5/1988. PMCID: PMC1493479.
19. Diehl AM, Mitchell MC, Herlong HF, Potter JJ, Wacker L, Mezey E. Changes in plasma amino acids during sobriety in alcoholic patients with and without liver disease. Am J Clin Nutr 44(4):453-60, 10/1986. PMID: 3766432.
20. Cha LY, Herlong HF, Mezey ES. [Treatment of experimental liver injury with a Chinese herbal medicine tablet]. Zhong Xi Yi Jie He Za Zhi 6(1):36-8, 5, 1/1986. PMID: 2942279.
21. Sarr MG, Herlong HF, Cameron JL. Long-term patency of the mesocaval C shunt. Am J Surg 151(1):98-103, 1/1986. PMID: 3484913.
22. Mitchell MC, Herlong HF. Alcohol and nutrition: caloric value, bioenergetics, and relationship to liver damage. Annu Rev Nutr 6:457-74, 1986. PMID: 3015171.
23. Diehl AM, Boitnott JK, Herlong HF, Potter JJ, Van Duyn MA, Chandler E, Mezey E. Effect of parenteral amino acid supplementation in alcoholic hepatitis. Hepatology 5(1):57-63, Jan-Feb, 1/1985. PMID: 3917968.
24. Cameron JL, Gayler BW, Sanfey H, Milligan F, Kaufman S, Maddrey WC, Herlong HF. Sclerosing cholangitis. Anatomical distribution of obstructive lesions. Ann Surg 200(1):54-60, 7/1984. PMCID: PMC1250392.
25. Diehl AM, Potter J, Boitnott J, Van Duyn MA, Herlong HF, Mezey E. Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis. Gastroenterology 86(4):632-6, 4/1984. PMID: 6698365.
26. Cameron JL, Herlong HF, Sanfey H, Boitnott J, Kaufman SL, Gott VL, Maddrey WC. The Budd-Chiari syndrome. Treatment by mesenteric-systemic venous shunts. Ann Surg 198(3):335-46, 9/1983. PMCID: PMC1353304.
27. Cameron JL, Gayler BW, Herlong HF, Maddrey WC. Sclerosing cholangitis: biliary reconstruction with Silastic transhepatic stents. Surgery 94(2):324-30, 8/1983. PMID: 6879446.
28. Wang KP, Yang P, Hutcheon DF, Herlong HF, Marsh BR, Hendrix T. A new method of injection sclerotherapy of esophageal varices. Gastrointest Endosc 29(1):38-40, 2/1983. PMID: 6600697.
29. Herlong HF, Recker RR, Maddrey WC. Bone disease in primary biliary cirrhosis: histologic features and response to 25-hydroxyvitamin D. Gastroenterology 83(1 Pt 1):103-8, 7/1982. PMID: 6978827.
30. Rector WG, Herlong HF, Moses H. Nonketotic hyperglycemia appearing as choreoathetosis or ballism. Arch Intern Med 142(1):154-5, 1/1982. PMID: 7053718.
31. Herlong HF, Hunter FM, Koff RS, Maddrey WC. A comparison of bumetanide and furosemide in the treatment of ascites. Cooperative study. J Clin Pharmacol 21(11-12 Pt 2):701-5, Nov-Dec, 11/1981. PMID: 7338582.
32. Spielberg SP, Gordon GB, Blake DA, Goldstein DA, Herlong HF. Predisposition to phenytoin hepatotoxicity assessed in vitro. N Engl J Med 305(13):722-7, 9/1981. PMID: 6790991.
33. Herlong HF, Russell RM, Maddrey WC. Vitamin A and zinc therapy in primary biliary cirrhosis. Hepatology 1(4):348-51, Jul-Aug, 7/1981. PMID: 7286911.
34. Herlong HF, Maddrey WC, Walser M. The use of ornithine salts of branched-chain ketoacids in portal-systemic encephalopathy. Ann Intern Med 93(4):545-50, 10/1980. PMID: 7001971.
35. Herlong HF, Reid PR, Boitnott JK, Maddrey WC. Aprindine hepatitis. Ann Intern Med 89(3):359-61, 9/1978. PMID: 686550.
36. Buse MG, Herlong HF, Weigand DA, Spicer SS. The effect of diabetes, insulin and Wallerian degeneration on leucine metabolism of isolated rat sciatic nerves. J Neurochem 27(6):1339-45, 12/1976. PMID: 1003207.
37. Buse MG, Herlong HF, Weigand DA. The effect of diabetes, insulin, and the redox potential on leucine metabolism by isolated rat hemidiaphragm. Endocrinology 98(5):1166-75, 5/1976. PMID: 1261511.

Book Chapters

1. Asamoah V, Herlong HF. Approach to the Patient with Abnormal Hepatic Laboratory Test. In: Surgery of the Alimentary Tract. Saunders Elsevier: Philadelphia, Pennsylvania. In Press.
2. Wong P, Herlong HF. Hepatic Encephalopathy. In: Current Surgical Therapy: Baltimore, Maryland, 2010.
3. Herlong HF. Pyogenic Liver Abscess. In: Clinical Infectious Disease. Cambridge University Press, 2008.
4. Moreman KM, Herlong HF. Refractory Ascites. In: Current Surgical Therapy: Baltimore, Maryland, 2008.
5. Prosser BJ, Herlong HF. Approach to the Patient with Abnormal Hepatic Laboratory Tests. In: Surgery of the Alimentary Tract. Saunders Elsevier: Philadelphia, Pennsylvania, 2007.
6. Mitchell MC, Herlong HF. Abdominal Pain and Irritable Bowel Syndrome. In: Principles of Ambulatory Medicine. Lippincott Williams and Wilkins, 2006.
7. Herlong HF, Mitchell MC. Disorders of the Esophagus: Dysphagia, non-cardiac chest pain, and Gastroesophageal Reflux. In: Principles of Ambulatory Medicine. Lippincott Williams and Wilkins, 2006.
8. Herlong HF, Mitchell MC,. Peptic Ulcer Disease. In: Principles of Ambulatory Medicine. Lippincott Williams and Wilkins, 2006.
9. Mitchell MC, Herlong HF. Selected Gastrointestinal Problems: Constipation and Diarrhea. In: Principles of Ambulatory Medicine. Lippincott Williams and Wilkins, 2006.
10. Mitchell MC, Herlong HF. Selected Gastrointestinal Problems II: Gastrointestinal Bleeding. In: Principles of Ambulatory Medicine. Lippincott Williams and Wilkins, 2006.
11. Velamati PF, Herlong HF. Treatment of Refractory Ascites. In: Current Treatment Options in Gastroenterology, 2006.
12. Haymart MR, Herlong HF. Cirrhosis. In: Conn's Current Therapy. W.B. Saunders: Houston, Texas, 2002.
13. Herlong HF. Hepatic Encephalopathy. In: Current Surgical Therapy. Mosby: Philadelphia, Pennsylvania, 2001.
14. Geyer AS, Rosenburg DS, Herlong HF, Provost TT,. Hepatitis. In: Cutaneous Medicine Cutaneous Manifestations of Systemic Disease. BC Becker, Inc: Hamilton London, 2001.
15. Klem J, Herlong HF. Pyogenic Liver Abscess. In: Current Therapy of Infectious Disease. Mosby: St. Louis, Missouri, 2001.
16. Herlong HF. Approach to the patient with Infection of the lIver. In: Infectious Diseases. Ed(s) Gorbach SL, Barlett JG, Blacklow NR. W.B. Saunders: Philadelphia, Pennsylvania, 1999.
17. Herlong HF. The Basic Clerkships and Electives. In: The Johns Hopkins University School of Medicine: Curriculum for the 21st Century. The Johns Hopkins University Press: Baltimore, Maryland, 1999.
18. Herlong HF,. Approach to the patient with liver disease. In: Principles and Practices of Medicine. Ed(s) Stobo JD, Hellmann DH, Ladenson PW, Petty BG, Traill TA. Appleton & Lange: Norwalk, Connecticut, 1996.
19. Herlong HF, Diehl AM. Chronic Liver Disease. In: Principles and Practices of Medicine. Appleton & Lange: Norwalk, Connecticut, 1996.
20. Herlong HF. Complications of Portal Hypertension. In: Principles and Practices of Medicine. Ed(s) Stobo JD, Hellmann DH, Ladenson PW, Petty BG, Traill TA. Appleton & Lange: Norwalk, Connecticut, 1996.
21. Hendrix TR, Giardiello FM, Herlong HF. Gastrointestinal Bleeding. In: Principles and Practices of Medicine. Appleton & Lange: Norwalk, Connecticut, 1996.
22. Herlong HF. Jaundice. In: Principles and Practices of Medicine. Ed(s) Stobo JD, Hellmann DH, Ladenson PW, Petty BG, Traill TA. Appleton & Lange: Norwalk, Connecticut, 1996.
23. Herlong HF. Biliary Cirrhosis. In: Current Therapy in Gastroenterology and Liver Disease. Mosby: St. Louis, Missouri, 1994.
24. Herlong HF, Mitchell, MC. Acute Diffuse Hepatocellular Disease: Viral Hepatitis and Drug-Induced Liver Disease. In: Principles and Practices of Medicine. Appleton & Century: Crofts, Norwalk, Connecticut, 1988.
25. Herlong HF. Chronic Active Hepatitis. In: Current Therapy in Allergy, Immunology and Rheumatology. BC Decker, Inc. Philadelphia, Pennsylvania, 1988.
26. Herlong HF. Endoscopic Sclerotherapy of Esophageal Variceal Hemorrhage. In: Current Surgical Therapy III. BC Decker, Inc. Canada, 1988.
27. Herlong HF. Jaundice. In: Principles and Practices of Medicine. Appleton & Century: Crofts, Norwalk, Connecticut, 1988.
28. Herlong HF, Mitchell, MC. Normal and Abnormal Hepatic Physiology: Biochemical and Radiologic Assessment of the Liver; and Classification of Diseases of the Liver. In: Principles and Practices of Medicine. Appleton & Century: Crofts, Norwalk, Connecticut, 1988.
29. Herlong HF. Portal Hypertension: Ascites, Spontaneous Bacterial Peritonitis, Hepatorenal Syndrome and Hepatic Encephalopathy. In: Principles and Practices of Medicine. Appleton & Century: Crofts, Norwalk, Connecticut, 1988.
30. Herlong HF, Johnson RT. Hepatic Encephalopathy. In: Current Therapy in Neurologic DIsease-2. BC Decker, Inc. Philadelphia, Pennsylvania, 1987.
31. Herlong HF. Hepatorenal Syndrome and Ascites. In: Current Therapy in Gastroenterology and Liver Disease. BC Decker, Inc. Philadelphia, Pennsylvania, 1986.
32. Diehl AM, Herlong HF. Cirrhosis. In: Conn's Current Therapy. WB Saunders Co. Philadelphia, Pennsylvania., 1985.
33. Scheinberg DA, Herlong MF. Gastrointestinal Agents. In: Manual of Drug Therapy. Raven Press: New York, New York, 1985.
34. Maddrey WC, Herlong HF. Acute Diffuse Hepatocellular Disease. In: Principles and Practice of Medicine. Appleton & Century: Crofts, Norwalk, Connecticut, 1984.
35. Maddrey WC, Herlong HF. Ascites, Spontaneous Bacterial Peritonitis: Hepatorenal Syndrome; Portal Hypertension and Hepatic Encephalopathy. In: Principles and Practice of Medicine. Appleton & Century: Crofts, Norwalk, Connecticut, 1984.
36. Herlong HF. Chronic Hepatitis. In: Current Therapy in Gastroenterology and Liver Disease. BC Decker, Inc. Philadelphia, Pennsylvania, 1984.
37. Herlong HF, Diehl AM,. Cirrhosis. In: Conn's Current Therapy. WB Saunders CO.,: Philadelphia, Pennsylvania, 1984.
38. Herlong HF. Primary Biliary Cirrhosis. In: Current Therapy in Gastroenterology and LIver Disease. Ed(s) Bayless TM. BC Decker, Inc. Philadelphia, Pennsylvania, 1984.
39. Maddrey WC, Herlong HF,. Biopsy of the Liver. In: Surgery of the Alimentary Tract. Ed(s) Shackelford RT, Zuidema GD. WB Saunders CO.,: Philadelphia, Pennsylvania, 1983.
40. Herlong HF, Maddrey WC,. Liver Function Testing. In: Surgery of the Alimentary Tract. Ed(s) Shackelford RT, Zuidema HD. WB Saunders Co. Philadelphia, Pennsylvania, 1983.
41. Herlong HF, Johannes RS. In: Problems in Internal Medicine: Selected Topics with Annotated bibiography. University Park Press: Baltimore, Maryland, 1980.
42. Herlong HF, Maddrey WC. Viral hepatitis. In: Prim Care. 6, 3, 505-15, 9/1979. ISBN: 118474.

Last updated: 7/11/2013