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Heath D Skinner, M.D, Ph.D.

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

2007 West Virginia University School of Medicine, Morgantown, WV, MD, Medicine
2007 West Virginia University School of Medicine, Morgantown, WV, PHD, Microbiology Immunology Cell Biology
2000 West Virginia University, Morgantown, WV, BA, Biology

Postgraduate Training

7/2008-6/2012 Residency, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
7/2007-6/2008 Internship, Internal Medicine, The University of Texas at Houston Medical School, Houston, TX

Experience/Service

Institutional Committee Activities

Member, Radiation Oncology Physics Curriculum committee, 2011-present
Member, Radiation Oncology Anderson Award 2010 Committee, 2010
Member, Radiation Oncology Quality and Safety Committee, 2009-2011

Honors and Awards

2012 Merit Award, American Society of Clinical Oncology
2012 The Lupe C. Garcia Fellowship in Cancer Research, The University of Texas MD Anderson Cancer Center
2012 The Thomas H. and Mayme P. Scott Fellowship in Cancer Research, The University of Texas MD Anderson Cancer Center
2011 Roentgen Resident/Fellow Research Award, Radiological Society of North America
2011 Trainee of the Quarter, The University of Texas MD Anderson Cancer Center
2010 Poster Walk Selection ASTRO Annual Meeting, Association of Residents in Radiation Oncology
2010 Trainee Research Day Award Finalist, The University of Texas MD Anderson Cancer Center
2010 Travel Award and Plenary Session Honors, American Society for Radiation Oncology
2009 Poster Walk Selection, ASTRO Annual Meeting, Association of Residents in Radiation Oncology
2005 First Place Honors in Oral Presentation, Graduate Student Division, Van Liere Research Convocation
2005 Second Place Honors in Poster Presentation Graduate Student Division, West Virginia University School of Medicine Van Liere Research Convocation
2004 Scholar-in-Training Award, American Association of Cancer Research
2000 Overall First Place Honors in Oral Presentation, West Virginia University School of Medicine Van Liere Research Convocation

Selected Publications

Peer-Reviewed Original Research Articles

1. Hamilton JD, Ahmed S, Sandulache VC, Daram SP, Ow TJ, Skinner HD, Rao A, Ginsberg LE, Kumar AJ, Myers JN. Improving imaging diagnosis for residual nodal disease after definitive therapy for oropharyngeal carcinoma: Specific signs for CT and best performance of combined criteria. AJNR 34(8):1637-1642, 8/2013.
2. Skinner HD, McCurdy MR, Echeverria AE, Lin SH, Welsh J, O'Reilly MS, Hofstetter WL, Ajani JA, Komaki R, Cox JD. Metformin use and improved response to therapy in esophageal adenocarcinoma. Acta Oncol. e-Pub 9/2012.
3. Sandulache VC, Ow TJ, Daram SP, Hamilton J, Skinner HD, Bell D, Rosenthal DI, Beadle BM, Ang K, Kies MS, El-Naggar AK, Myers JN. Residual nodal disease in patients with advanced-stage oropharyngeal squamous cell carcinoma treated with definitive radiation therapy and post-treatment neck dissection is associated with local-regional recurrence, distant metastasis and decreased survival. Head and Neck. e-Pub 9/2012.
4. Sandulache VC, Skinner HD, Wang Y, Chen Y, Dodge CT, Ow TJ, Bankson JA, Myers JN, Lai SY. Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation. Mol Cancer Ther 11(6):1373-80, 6/2012. e-Pub 5/2012. PMID: 22572813.
5. Skinner HD, Sandulache VC, Ow TJ, Meyn RE, Yordy JS, Beadle BM, Fitzgerald AL, Giri U, Ang KK, Myers JN. TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence. Clin Cancer Res 18(1):290-300, 1/1/2012. e-Pub 11/16/2011. PMCID: PMC3251726.
6. Sandulache VC, Skinner HD, Ow TJ, Zhang A, Xia X, Luchak JM, Wong LC, Pickering CR, Zhou G, Myers JN. Individualizing anti-metabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status. Cancer 118(3):711-712, 2012.
7. Skinner HD, Garden AS, Rosenthal DI, Ang KK, Morrison WH, Esmaeli B, Pinnix CC, Frank SJ. Outcomes of malignant tumors of the lacrimal apparatus: The University of Texas MD Anderson Cancer Center Experience. Cancer 117(12):2801-2010, 2011.
8. Skinner HD, Sharp HJ, Kaseb AO, Javle MN, Vauthey JN, Abdalla EK, Delclos ME, Das P, Crane CH, Krishanan S. Radiation treatment outcomes for unresectabel hepatocellular carcinoma. Acta Oncol 50(8):1191-1198, 2011.
9. Jiang Y, Cukic B, Adjeroh DA, Skinner HD, Lin J, Shen QJ, Jiang BH. An algorithm for identifying novel targets of transcription factor families: application to hypoxia-inducible factor 1 targets. Cancer Infom 7:75-89, 2009.
10. Zhong XS, Liu LZ, Skinner HD, Cao Z, Ding M, Jiang BH. Mechanism of vascular endothelial growth factor expression mediated by cisplatin in human ovarian cancer cells. Biochem Biophys Res Commun 358(1):92-98, 2007.
11. Frankenberry K, Skinner HD, Somasundar P, McFadden D, Vona-Davis L. Leptin receptor expression and cell signaling in breast cancer. Int J Oncol 28(4):985-993, 2006.
12. Griffin WC 3rd Skinner HD, Birkle DL. Prenatal stress influences 8-OH-DPAT modulated startle responding and [(3)]-8-OH-DPAT binding in rats. Pharmacol Biochem Behav 81(3):601-607, 2005.
13. Skinner HD, Zhong XS, Gao N, Jiang BH. Arsenite induces p70S6K1 activation and HIF-1α levels in prostate cancer cells. Mol Cell Biochem 255(1-2):19-23, 2004.
14. Somasudar P, Krankenberry K, Skinner HD, Vedula G, McFadden D, Riggs D, Jackson B, Vangilder R, Hileman S, Vona-Davis L. Prostate cancer cell proliferation is influenced by leptin. J Surg Res 1(118):71-82, 2004.
15. Skinner HD, Zheng J, Gao N, Agani F, Jiang BH. VEGF transcriptional acrtivity via HIF-1α expression is dependent upon P13K-mediated activation of p70S6K and hdm2 in ovarian cancer. J Biol Chem 279(44):45643-45651, 2004.
16. Griffin WC 3rd, Skinner HD, Salm AK, Birkle DL. Mild prenatal stress in rats is associated with enhanced conditioned fear. Physiol Behav 79(2):209-215, 2003.

Invited Articles

1. Skinner HD, Holsinger C, Beadle BM. Cancer of the oropharynx. Curr Probl Cancer. e-Pub 9/2012.
2. Skinner HD, Hong T, Krishnan S. Charged particle therapy for hepatocellular carcinoma. Semin Radiat Oncol 21(4):278-286, 2011.

Editorials

1. Skinner HD, Krishnan S. Predicting, preventing, treating and understanding radiation nephropath. J Gastro Oncol 1:2-4, 2010.

Book Chapters

1. Skinner HD, Deorukhkar AA, Krishnan S. Molecular basis of cancer radiation treatment. In: Principles of Molecular Diagnostics and Personalized Cancer Medicine. In Press.
2. Manon RR, Myers JN, Khuntia D, Skinner HD, Harari P. Oral cavity cancer. In: Principles and Practice of Radiation Oncology. In Press.

Last updated: 8/19/2013