| Ivan Gorlov, PhD |
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education | |
| 1994 | Institute of Cytology and Genetics, Novosibirsk, Russian Federation, DSc, Computational Biology |
| 1990 | Institute of Cytology and Genetics, Novosibirsk, Russian Federation, PHD, Bioinformatics |
| 1982 | Novosibirsk University, Novosibirsk, Russian Federation, MS, Genetics |
Postgraduate Training | |
| 2003-2005 | Research Fellowship, Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 1999-2001 | Research Fellowship, Molecular Genetics, Baylor College of Medicine, Houston, TX |
| 1994-1998 | Research Fellowship, Evolutionary Genetics, Institute of Evolution, University of Haifa, Israel |
| 1982-1984 | Probationer, Evolutionary Genetics, Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russian Federation |
Experience/Service
Academic Appointments
Assistant Professor, Department of Epidemiology, Division of OVP, Cancer Prevention and Population Sciences, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 6/2007-9/2008
Instructor, Department of Epidemiology, Division of OVP, Cancer Prevention and Population Sciences, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 2005-2007
Postdoctoral Fellow, Department of Epidemiology, Division of OVP, Cancer Prevention and Population Sciences, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 2003-2005
Research Investigator, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 2001-2003
Leading Researcher, Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russian Federation, 1999
Associate Professor, Tottori University, Tottori, Japan, 1997
Leading Researcher, Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russian Federation, 1996-1997
Leading Researcher, Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russian Federation, 1994-1995
Senior Researcher, Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russian Federation, 1990-1994
Junior Researcher, Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russian Federation, 1984-1989
Selected Publications
Peer-Reviewed Original Research Articles | ||
| 1. | Chen J, Pande M, Huang YJ, Wei C, Amos CI, Talseth-Palmer BA, Meldrum CJ, Chen WV, Gorlov IP, Lynch PM, Scott RJ, Frazier ML. Cell cycle-related genes as modifiers of age of onset of colorectal cancer in Lynch syndrome: a large-scale study in non-Hispanic white patients. Carcinogenesis 34(2):299-306, 2/2013. e-Pub 11/2012. PMCID: PMC3564440. | |
| 2. | Walsh KM, Gorlov IP, Hansen HM, Wu X, Spitz MR, Zhang H, Lu EY, Wenzlaff AS, Sison JD, Wei C, Lloyd SM, Chen W, Frazier ML, Seldin MF, Bierut LJ, Bracci PM, Wrensch MR, Schwartz AG, Wiencke JK, Amos CI. Fine-mapping of the 5p15.33, 6p22.1-p21.31 and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. Cancer Epidemiol Biomarkers Prev 22(2):251-60, 2/2013. e-Pub 12/2012. PMCID: PMC3565099. | |
| 3. | Walsh KM, Amos CI, Wenzlaff AS, Gorlov IP, Sison JD, Wu X, Spitz MR, Hansen HM, Lu EY, Wei C, Zhang H, Chen W, Lloyd SM, Frazier ML, Bracci PM, Seldin MF, Wrensch MR, Schwartz AG, Wiencke JK. Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans. Oncotarget 3(11):1428-38, 11/2012. PMID: 23232035. | |
| 4. | Spitz MR, Gorlov IP, Dong Q, Wu X, Chen W, Chang DW, Etzel CJ, Caporaso NE, Zhao Y, Christiani DC, Brennan P, Albanes D, Shi J, Thun M, Landi MT, Amos CI. Multistage Analysis of Variants in the Inflammation Pathway and Lung Cancer Risk in Smokers. Cancer Epidemiol Biomarkers Prev 21(7):1213-21, 7/2012. e-Pub 5/2012. PMID: 22573796. | |
| 5. | Gorlov IP, Byun J, Logothetis CJ. In silico functional profiling of individual prostate cancer tumors: many genes, few functions. Cancer Genomics Proteomics 9(3):109-14, May-Jun, 5/2012. PMID: 22593245. | |
| 6. | Gorlov IP, Byun J, Zhao H, Logothetis CJ, Gorlova OY. Beyond comparing means: the usefulness of analyzing interindividual variation in gene expression for identifying genes associated with cancer development. J Bioinform Comput Biol 10(2):1241013, 4/2012. PMID: 22809348. | |
| 7. | Kaftanovskaya EM, Huang Z, Barbara AM, De Gendt K, Verhoeven G, Gorlov IP, Agoulnik AI. Cryptorchidism in Mice with an Androgen Receptor Ablation in Gubernaculum Testis. Mol Endocrinol 26(4):598-607, 4/2012. e-Pub 2/2012. PMCID: PMC3327355. | |
| 8. | Gorlova OY, Ying J, Amos CI, Spitz MR, Peng B, Gorlov IP. Derived SNP alleles are used more frequently than ancestral alleles as risk-associated variants in common human diseases. J Bioinform Comput Biol 10(2):1241008, 4/2012. PMID: 22809343. | |
| 9. | Gorlov IP, Logothetis CJ, Fang S, Gorlova OY, Amos C. Building a statistical model for predicting cancer genes. PLoS One 7(11):e49175, 2012. e-Pub 11/2012. PMCID: PMC3499550. | |
| 10. | Chen X, Gorlov IP, Ying J, Merriman KW, Kimmel M, Lu C, Reyes-Gibby CC, Gorlova OY. Initial medical attention on patients with early-stage non-small cell lung cancer. PLoS One 7(3):e32644, 2012. e-Pub 3/2012. PMCID: PMC3296738. | |
| 11. | Spitz MR, Gorlov IP, Amos CI, Dong Q, Chen W, Etzel CJ, Gorlova OY, Chang DW, Pu X, Zhang D, Wang L, Cunningham JM, Yang P, Wu X. Variants in inflammation genes are implicated in risk of lung cancer in never smokers exposed to second-hand smoke. Cancer Discov 1(5):420-9, 10/2011. e-Pub 8/2011. PMID: 22586632. | |
| 12. | Zhao H, Logothetis CJ, Gorlov IP. Usefulness of the top-scoring pairs of genes for prediction of prostate cancer progression. Prostate Cancer Prostatic Dis 13(3):252-9, 9/2010. e-Pub 4/13/2010. PMID: 20386565. | |
| 13. | Amos CI, Gorlov IP, Dong Q, Wu X, Zhang H, Lu EY, Scheet P, Greisinger AJ, Mills GB, Spitz MR. Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study. J Natl Cancer Inst 102(15):1199-205, 8/4/2010. e-Pub 6/16/2010. PMCID: PMC2914761. | |
| 14. | Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T, Dong Q, Zhang Q, Gu X, Vijayakrishnan J, Sullivan K, Matakidou A, Wang Y, Mills G, Doheny K, Tsai YY, Chen WV, Shete S, Spitz MR, Houlston RS. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet 40(5):616-22, 5/2008. e-Pub 4/2/2008. PMCID: PMC2713680. | |
| 15. | Gorlov IP, Gorlova OY, Sunyaev SR, Spitz MR, Amos CI. Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms. Am J Hum Genet 82(1):100-12, 1/2008. PMCID: PMC2253956. | |
| 16. | Gorlov IP, Gorlova OY, Amos CI. Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome. BMC Genomics 17(9):292, 2008. e-Pub 6/17/2008. PMCID: PMC2442617. | |
| 17. | Yang H, Spitz MR, Stewart DJ, Lu C, Gorlov IP, Wu X. ATM sequence variants associate with susceptibility to non-small cell lung cancer. Int J Cancer 121(10):2254-9, 11/15/2007. PMID: 17582598. | |
| 18. | Gorlov IP, Meyer P, Liloglou T, Myles J, Boettger MB, Cassidy A, Girard L, Minna JD, Fischer R, Duffy S, Spitz MR, Haeussinger K, Kammerer S, Cantor C, Dierkesmann R, Field JK, Amos CI. Seizure 6-like (SEZ6L) gene and risk for lung cancer. Cancer Res 67(17):8406-11, 9/2007. PMID: 17804757. | |
| 19. | Gorlov IP, Kimmel M, Amos CI. Strength of the purifying selection against different categories of the point mutations in the coding regions of the human genome. Hum Mol Genet 15(7):1143-50, 4/2006. e-Pub 2/2006. PMID: 16500998. | |
| 20. | Gorlov IP, Gorlova OY, Amos CI. Predicting the oncogenicity of missense mutations reported in the International Agency for Cancer Research (IARC) mutation database on p53. Hum Mutat 26(5):446-54, 11/2005. PMID: 16173033. | |
| 21. | Gorlov IP, Gorlova OY, Frazier ML, Amos CI. Missense mutations in cancer suppressor gene TP53 are colocalized with exonic splicing enhancers (ESEs). Mutat Res 554(1-2):175-83, 10/2004. PMID: 15450416. | |
| 22. | Lin J, Spitz MR, Wang Y, Schabath MB, Gorlov IP, Hernandez LM, Pillow PC, Grossman HB, Wu X. Polymorphisms of folate metabolic genes and susceptibility to bladder cancer: a case-control study. Carcinogenesis 25(9):1639-47, 9/2004. e-Pub 4/29/2004. PMID: 15117811. | |
| 23. | Gorlov IP, Gorlova OY, Frazier ML, Amos CI. Missense mutations in hMLH1 and hMSH2 are associated with exonic splicing enhancers. Am J Hum Genet 73(5):1157-61, 11/2003. e-Pub 10/2003. PMCID: PMC1180494. | |
| 24. | Mishra R, Gorlov IP, Chao LY, Singh S, Saunders GF. PAX6, paired domain influences sequence recognition by the homeodomain. J Biol Chem 277(51):49488-94, 12/2002. e-Pub 10/2002. PMID: 12388550. | |
| 25. | Gorlov IP, Kamat A, Bogatcheva NV, Jones E, Lamb DJ, Truong A, Bishop CE, McElreavey K, Agoulnik AI. Mutations of the GREAT gene cause cryptorchidism. Hum Mol Genet 11(19):2309-18, 9/15/2002. PMID: 12217959. | |
| 26. | Gorlov IP, Saunders GF. A method for isolating alternatively spliced isoforms: isolation of murine Pax6 isoforms. Anal Biochem 15(2):401-4, 9/2002. PMID: 12419357. | |
| 27. | Gorlov IP, Gorlova OY. Cost-benefit analysis of recombination and its application for understanding of chiasma interference. J Theor Bio 213(1):1-8, 11/2001. PMID: 11708850. | |
| 28. | Overbeek PA, Gorlov IP, Sutherland RW, Houston JB, Harrison WR, Boettger-Tong HL, Bishop CE, Agoulnik AI. A transgenic insertion causing cryptorchidism in mice. Genesis 30(1):26-35, 5/2001. PMID: 11353515. | |
| 29. | Overbeek PA, Gorlov IP, Bishop CE, Sutherland R, Boettger-Tong1 HL, Agoulnik AI. crsp-a new mouse transgene insertional mutation causing cryptorchidism. Genesis 30:26-35, 2001. | |
| 30. | Gorlova OIu, Gorlov IP. [Variation in the relative length of chromosomes in mammalian karyotypes. Hypothesis of equalizing selection]. Genetika 36(6):725-39, 6/2000. PMID: 10923254. | |
| 31. | Gorlov IP, Tsurusaki N. Morphology and meiotic/mitotic behavior of B chromosomes in a Japanese Harvestman, Metagagrella tenuipes (arachnida: opiliones): No evidence for B accumulation mechanisms. Zoolog Sci 17(3):349-55, 4/2000. PMID: 18494590. | |
| 32. | Gorlov IP, Tsurusaki N. Analysis of the phenotypic effects of B chromosomes in a natural population of Metagagrella tenuipes (Arachnida: Opiliones). Heredity 84:209-217, 2/2000. PMID: 10762391. | |
| 33. | Gorlov IP, Tsurusaki N. Staggered clines in a hybrid zone between two chromosome races of the harvestman Gagrellopsis nodulifera (Arachnida: Opiliones). Evolution 54(1):176-90, 2/2000. PMID: 10937194. | |
| 34. | Gorlov IP, Tsurusaki N. Morphology and meiotic/mitotic hehaviour of B chromosocmes in a Japanese Harvestman, Metagagrella tenuipes (Arachinida: Opiliones); no evidence for B accumulation mechanism. Zoological Science 17:349-355, 2000. | |
| 35. | Gorlova O Yu, Gorlov IP. Variation of relative chromosomal lengths in mammalian karyotypes. A hypothesis of leveling selection. Genetika 36:1-15, 2000. | |
| 36. | Gorlov I, Gorlova O, Ivanitskaya E, Korol A, Nevo E. Recombination in subterranean mole rat Spalax ehrenbergi superspecies: ecological and cytogenetic determinants. Israel Journal of Zoology 45:306-307, 1999. | |
| 37. | Gorlova O Yu, Gorlov IP, Nevo E, Logunov DV. Cytogenetic studies on seventeen spider species from Israel. Bulletin of the British Arachnologival Society 10:249-252, 1997. | |
| 38. | Ivanitskaya E, Gorlov I, Gorlova O, Nevo E. Chromosome markers for Mus macedonicus (Rodentia, Muridae) from Israel. Hereditas 124:145-150, 1996. | |
| 39. | Gorlov IP, Borodin PM. Recombination in single and double heterozygotes for two partially overlapping inversions in chromosome 1 of the house mouse. Heredity 75 ( Pt 2):113-25, 8/1995. PMID: 7558886. | |
| 40. | Gorlov IP, Gorlova O. Yu, Longunov DV. Cytogenetic studies on Siberian spiders. Hereditas 122:211-220, 1995. | |
| 41. | Gorlov IP, Zhelezova AI, Gorlova OYu . Sex differences in chiasma distribution along two marked mouse chromosomes; differences in chiasma distribution as a reason for sex differences in recombination frequency. Genet Res 64(3):161-166, 12/1994. PMID: 7698640. | |
| 42. | Gorlov IP, Chepkasov IL, Kalinina OIu, Borodin PM. [Meiotic crossing over--not the only source of recombinants in man]. Genetika 29(12):2000-10, 12/1993. PMID: 8119579. | |
| 43. | Gorlov IP, Ladygina TYu , Borodin PM. Chiasma distribution in the first bivalent of mice carrying a double insertion of homogeneously-staining regions in homo- and heterozygous states. Heredity 70 ( Pt 6):642-7, 6/1993. PMID: 8392989. | |
| 44. | Borodin PM, Rodionova MI, Sablina OV, Gorlov IP. [An unusual heteromorphic bivalent in the common vole (Microtus arvalis) from Byelarus]. Genetika 29(4):613-9, 4/1993. PMID: 8354471. | |
| 45. | Gorlov IP, Gusachenko AM, Vysotskaia LV. [Cytogenetic analysis of recombination interactions]. Genetika 29(2):288-95, 2/1993. PMID: 8486259. | |
| 46. | Gorlov IP, Gusachenko AM, Vysotskaya LV. A cytogenetic and analysis of recombination interactions. Genetika 29:2000-2010, 1993. | |
| 47. | Kalinina O Yu, Gorlov IP. An effect of recombination on population density and fitness: a comparison of models with free recombination and without recombination. Doklady Academii Nauk (Proceedings of Russia Academy of Science) 332:95-99, 1993. | |
| 48. | Gorlov IP, Chepkasov IL, Kalinina O Yu, Borodin PM. Meiotic crossing over is not the only source of human recombinants. Genetika 29:2000-2010, 1993. | |
| 49. | Borodin PM, Gorlov IP, Ladygina TYu. Synaptic interrelationships between the segments of the heteromorphic bivalent in double heterozygotes for paracentric inversions in chromosome 1 of the house mouse. Chromosoma 101(5-6):374-9, 3/1992. PMID: 1576887. | |
| 50. | Gorlov I, Schuler L, Bunger L, Borodin P. Chiasma frequency in strains of mice selected for litter size and for high body weight. Theor. Appl. Genet 84:640-642, 1992. | |
| 51. | Borodin PM, Rodionova MI, Sablina OV, Gorlov IP. Unusual heteromorphic bivalents in the common vole (Microtus arvalis) from Belorussia. Cytogenet Cell Genet 60(2):123-7, 1992. PMID: 1535306. | |
| 52. | Borodin PM, Gorlov IP, Agulnik AI, Agulnik SI, Ruvinsky AO. Chromosome pairing and recombination in mice heterozygous for different translocations in chromosomes 16 and 17. Chromosoma 101(4):252-8, 12/1991. PMID: 1773663. | |
| 53. | Gorlov IP, Ladygina T Y, Serov OL, Borodin PM. Positional control of chiasma distribution in the house mouse. Chiasma distribution in mice homozygous and heterozygous for an inversion in chromosome 1. Heredity 66 ( Pt 3):453-8, 6/1991. PMID: 1880050. | |
| 54. | Gorlov IP, Ladygina TIu, Serov OL, Borodin PM. [Chromosomal control of chiasma distribution in house mice. Analysis of chiasma distribution in homo- and heterozygotes by inversion in chromosome 1]. Genetika 27(5):820-7, 5/1991. PMID: 1916251. | |
| 55. | Gorlov IP, Borodin PM. [Chiasmata distribution in the normal karyotype of mice]. Genetika 27(2):247-51, 2/1991. PMID: 1874434. | |
| 56. | Borodin PM, Gorlov IP, Agul'nik AI, Agul'nik SI, Rubinskii AO. [Synapsis and chiasma distribution in mice heterozygous for translocations in chromosomes 16 and 17]. Genetika 27(2):252-62, 2/1991. PMID: 1874435. | |
| 57. | Gorlov I, Borodin PM. Chiasma distribution in normal mouse karyotype. Genetika 27:247-251, 1991. | |
| 58. | Agulnik SI, Borodin PM, Gorlov IP, Ladygina TYu , Pak SD. The origin of a double insertion of homogeneously staining regions in the house mouse (Mus musculus musculus). Heredity 65 ( Pt 2):265-7, 10/1990. PMID: 1703140. | |
| 59. | Borodin PM, Gorlov IP, Ladygina TYu. Synapsis in single and double heterozygotes for partially overlapping inversions in chromosome 1 of the house mouse. Chromosoma 99(5):365-70, 9/1990. PMID: 2265572. | |
| 60. | Borodin PM, Gorlov IP, Ladygina TIu. [Synapsis in single and double heterozygotes for partially overlapping inversions in chromosome 1 of the house mouse]. Genetika 26(7):1279-88, 7/1990. PMID: 2227401. | |
| 61. | Gorlov IP. Cytogenetic study of synapsis and crossing-over in male mice heterozygous for reciprocal translocation T(14; 15)6Ca. Genetika 26(7):1178-86, 7/1990. PMID: 2227399. | |
| 62. | Gorlov IP, Ladygina TIu, Borodin PM. Synapsis and recombination of chromosomes in the house mouse homozygous for the double inversion of the homogeneously stained regions in chromosome 1. Genetika 26(4):657-63, 4/1990. PMID: 1695596. | |
| 63. | Borodin PM, Gorlov IP, Ladygina TYu. Double insertion of homogeneously staining regions in chromosome 1 of wild Mus musculus musculus: effects on chromosome pairing and recombination. J Hered 81(2):91-5, Mar-Apr, 3/1990. PMID: 2159965. | |
| 64. | Agul'nik SI, Borodin PM, Gorlov IP, Ladygina TIu, Pak SD. The causes of appearance of a double insertion of homogeneously staining regions in the chromosome 1 of house mouse (Mus musculus musculus). Genetika 26(3):570-2, 3/1990. PMID: 1693902. | |
| 65. | Gorlov I, Borodin PM, Ladygina T Yu. Synapsis in single and double heterozgotes for partially overlapping inversions in chromosome 1 of the house mouse. Chromosoma 99:365-370, 1990. | |
| 66. | Borodin PM, Ladygina TIu, Gorlov IP. Effect of heterozygosity for insertions of homogeneously stained regions in chromosome 1 of the house mouse on synapsis in meiotic prophase. Genetika 25(2):214-9, 2/1989. PMID: 2472304. | |
| 67. | Agul'nik SI, Gorlov IP, Agul'nik AI. A new variant of chromosome 1 in the house mouse. Tsitologiia 30(6):773-6, 6/1988. PMID: 3176181. | |
| 68. | Gorlov IP. Distribution of chiasmas in the 2d and 6th chromosomes involved in Robertsonian translocations in male mice. Genetika 24(4):641-7, 4/1988. PMID: 3396871. | |
| 69. | Gorlov IP, Agul'nik AI, Agul'nik SI. Localization of genes on mouse chromosomes by comparing the genetic map and chiasma distribution. Genetika 23(1):63-70, 1/1987. PMID: 3469124. | |
| 70. | Gorlov IP, Borodin PM. Effect of emotional stress on the frequency of meiotic abnormalities in male mice. Genetika 22(6):1019-24, 6/1986. PMID: 3732800. | |
| 71. | Borodin PM, Gorlov IP. Cytogenetic consequences of hybridization between wild and laboratory mice. Genetika 22(5):855-60, 5/1986. PMID: 3732798. | |
Invited Articles | ||
| 1. | Chen X, Gorlov IP, Merriman KW, Weng SF, Foy M, Keener G, Amos CI, Spitz MR, Kimmel M, Gorlova OY. Association of smoking with tumor size at diagnosis in non-small cell lung cancer. Lung Cancer 74(3):378-83, 12/2011. e-Pub 6/2011. PMCID: PMC3197014. | |
| 2. | Pande M, Spitz MR, Wu X, Gorlov IP, Chen WV, Amos CI. Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk. Carcinogenesis 32(10):1493-9, 10/2011. e-Pub 7/2011. PMCID: PMC3179422. | |
| 3. | Gorlov IP, Gorlova OY, Frazier ML, Spitz MR, Amos CI. Evolutionary evidence of the impact of rare variants on disease etiology. Clin Genet 79(3):199-206, 3/2011. e-Pub 9/2010. PMID: 20831747. | |
| 4. | Kaftanovskaya EM, Feng S, Huang Z, Tan Y, Barbara AM, Kaur S, Truong A, Gorlov IP, Agoulnik AI. Suppression of insulin-like3 receptor reveals the role of B-catentin and Notch signaling in gubernaculum development. Mol Endocrinol 25(1):170-83, 1/2011. e-Pub 12/2010. PMCID: PMC3089031. | |
| 5. | Hirschfield GM, Liu X, Han Y, Gorlov IP, Lu Y, Xu C, Lu Y, Chen W, Juran BD, Coltescu C, Mason AL, Milkiewicz P, Myers RP, Odin JA, Luketic VA, Speiciene D, Vincent C, Levy C, Gregersen PK, Zhang J, Heathcote EJ, Lazaridis KN, Amos CI, Siminovitch KA. Variants at IRF5-TNP03, 17q12-21 and MMEL 1 are associated with primary billary cirrhosis. Nat Genet 42(8):655-7, 8/2010. e-Pub 7/2010. PMCID: PMC2929126. | |
| 6. | Gorlov IP, Sircar K, Zhao H, Maity SN, Navone NM, Gorlova OY, Troncoso P, Pettaway CA, Byun JY, Logothetis CJ. Prioritizing genes associated with prostate cancer development. BMC Cancer 2(10):599, 2010. e-Pub 11/2/2010. PMCID: PMC2988752. | |
| 7. | Gorlov I, Gorlova OY. Selection in recent human evolution. Proceedings of Russian Genetic Society 22:45-57, 2006. | |
Abstracts | ||
| 1. | Gorlov I, Gorlova OY, Amos C, Logothetis C. GWAS meets microarray. Proc Amer Soc Human Gen 59, 10/2010. | |
| 2. | Gorlov I, Zhao H. Usefulness of the top-scoring pairs of genes for prediction of prostate cancer progression. Proc Amer Assoc Cancer Res 47:205, 3/2010. | |
| 3. | Gorlov IP, Amos C. SNP density in coding regions of the human genome. Proc Amer Assoc Cancer Res 45:4706, 3/2008. | |
| 4. | Gorlov I, Gorlova OY, Sunyaev S, Spitz MR, Amos C. The optimal Minor Allele Frequency (OMAF) for a SNP-disease association studies. Proceedings of the 56th The American Society of Human Genetics Annual Meeting:53, 10/2006. | |
| 5. | Gorlov I, Kimmel, M, Amos C. Using single-nucleotide polymorphisms (SNPs) to quantitate selection against nonsense, missense and silent mutations. Proceedings of the 55th The American Society of Human Genetics Annual Meeting 201, 10/2005. | |
| 6. | Gorlov I, Amos CI. Strength of selection against point mutations in coding regions of the human geneome. Proceedings of the AACR 94th Annual Meeting 44:965, 7/2003. | |
| 7. | Gorlov I, Gorlova OY, Frazier M, Amos C. Missense mutations in cancer suppresssor gene TP53 are associated with Exonic Splicing enhancers (ESEs). Am J Human Genet 73 (suppl):242, 2003. | |
| 8. | Gorlov I, Saunders G. Novel splice variant of the PAX6 gene. Proceedings of the 74th Annual The American Society of Biochemistry and Molecular Biology meeting 45, 5/2002. | |
| 9. | Gorlov IP, Tsurusaki N. Staggered clines in a hybrid zone between two chromosomal races of the harvestman Gagrellopsis noduliferea (Arachnida: Opiliones). Evolution 54(1):176-190, 2/2000. PMID: 10937194. | |
Book Chapters | ||
| 1. | Gorlov I. Genetic Control of Recombination. In: Recombination. Shtiica, 1998. | |
Grant & Contract Support
| Title: | Genetic Analysis of Anticipation in Lynch Syndrome |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-Investigator |
| Duration: | 12/10/2010 - 11/30/2013 |
| Title: | Clinical Research Consortium PP-3 |
| Funding Source: | Prostate Cancer Foundation |
| Role: | Co-Investigator |
| Principal Investigator: | Christopher Logothetis |
| Duration: | 1/11/2010 - 1/10/2013 |
| Title: | Tobacco Smoke Sensitive Genes and Genetic Susceptibility to Small-Cell Lung Cancer |
| Funding Source: | NIH |
| Role: | Principal Investigator |
| Duration: | 10/1/2008 - 9/30/2010 |
| Title: | The Effect of Polymorphic CA Repeats in the 5' Regulatory Region of the EGFR Gene (rs11568315) on Breast Cancer Risk |
| Funding Source: | NIH |
| Role: | Principal Investigator |
| Duration: | 9/1/2008 - 8/31/2010 |
| Title: | Molecular Genetics of HNPCC |
| Funding Source: | NIH |
| Role: | Co-Investigator |
| Principal Investigator: | Marsha Frasier |
| Duration: | 8/1/2008 - 7/30/2012 |
| Title: | Inflammation Genes and Lung Cancer Risk |
| Funding Source: | NIH |
| Role: | Co-Investigator |
| Principal Investigator: | Margaret Spitz, MD |
| Duration: | 7/1/2008 - 6/30/2012 |
| Title: | Genetic Mechanism of Bone Metastasis of Prostate Cancer |
| Funding Source: | The UT MD Anderson Prostate Cancer Research Project |
| Role: | Principal Investigator |
| Duration: | 11/1/2007 - 10/31/2008 |
| Title: | High Density Association Analysis of Lung Cancer |
| Funding Source: | NIH |
| Role: | Co-Investigator |
| Principal Investigator: | Christopher Amos |
| Duration: | 7/1/2007 - 6/30/2012 |
Last updated: 5/13/2013
- Global Navigation
- About Us
- Locations
- Calendar
- Careers
- Publications
- How You Can Help
- Contact Us
- Newsroom
- Site Index
- Patient and Cancer Information
- myMDAnderson
- Cancer Information
- Patient Information
- Care Centers & Clinics
- Children's Cancer Hospital
- Services & Amenities
- Education and Research
- Departments, Programs and Labs
- PeopleFinder
- Research at MD Anderson
- Education & Training
- Resources for Professionals
- For Employees
- Employee Alert Information
- Employee Resources
- Doing Business
- Vendors & Suppliers
- Partners & Affiliates
- Legal and Policy
- Legal Statements
- Site Policies
- Reporting Fraud, Waste & Abuse
© 2010 The University of Texas M. D. Anderson Cancer Center

