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Jianjun Shen

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Carcinogenesis, Division of Basic Science Research, The University of Texas M.D. Anderson Cancer Center, Smithville, TX

Education & Training

Degree-Granting Education

1992 Rutgers, The State University of New Jersey, Newark, NJ, PHD, Physical Biochemistry
1990 Rutgers, The State University of New Jersey, Newark, NJ, MS, Chemistry
1983 Nanjing Institute of Technology, Nanjing, Jiangsu Province, BS, Chemistry

Experience/Service

Academic Appointments

Facility Core Director, Department of Carcinogenesis, Division of Basic Science Research, The University of Texas M.D. Anderson Cancer Center, Smithville, TX, 1/1998-present

Selected Publications

Peer-Reviewed Original Research Articles
1. Short JD, Houston KD, Dere R, Cai SL, Kim J, Johnson CL, Broaddus RR, Shen J, Miyamoto S, Tamanoi F, Kwiatkowski D, Mills GB, Walker CL. AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27. Cancer Res 68(16):6496-506, 8/2008. PMID: 18701472.
2. Xu H, Shen J, Walker CL, Kleymenova E. Tissue-specific expression and splicing of the rat polycystic kidney disease 1 gene. DNA Seq 12(5-6):361-6, 12/2001. PMID: 11913782.
3. Kiguchi K, Carbajal S, Chan K, Beltran L, Ruffino L, Shen J, Matsumoto T, Yoshimi N, DiGiovanni J. Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma. Cancer Res 61(19):6971-6, 10/2001. PMID: 11585718.
4. Li D, Zhang W, Zhu J, Chang P, Sahin A, Singletary E, Bondy M, Hazra T, Mitra S, Lau S, Shen J, DiGiovanni J. Oxidative DNA damage and 8-hydroxy-2-deoxyguanosine DNA glycosylase/apurinic lyase in human breast cancer. Mol Carcinog 31(4):214-23, 8/2001. PMID: 11536371.
5. Yan M, Qiang W, Liu N, Shen JJ, Lynn WS, Wong PK. The ataxia-telangiectasia gene product may modulate DNA turnover and control cell fate by regulating cellular redox in lymphocytes. Faseb J 15(7):1132-8, 5/2001. PMID: 11344081.
6. Shen JJ, Matern D, Millington DS, Hillman S, Feezor MD, Bennett MJ, Qumsiyeh M, Kahler SG, Chen YT, Van Hove JL. Acylcarnitines in fibroblasts of patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and other fatty acid oxidation disorders. J Inherit Metab Dis 23(1):27-44, 2/2000. PMID: 10682306.
7. Shen J, Liu HM, McConkie-Rosell A, Chen YT. Prenatal diagnosis and carrier detection for glycogen storage disease type III using polymorphic DNA markers. Prenat Diagn 18(1):61-4, 1/1998. PMID: 9483641.
8. Shen J, Liu HM, Bao Y, Chen YT. Polymorphic markers of the glycogen debranching enzyme gene allowing linkage analysis in families with glycogen storage disease type III. J Med Genet 34(1):34-8, 1/1997. PMCID: PMC1050844.
9. Shen J, Bao Y, Chen YT. A nonsense mutation due to a single base insertion in the 3'-coding region of glycogen debranching enzyme gene associated with a severe phenotype in a patient with glycogen storage disease type IIIa. Hum Mutat 9(1):37-40, 1997. PMID: 8990006.
10. Shen J, Bao Y, Liu HM, Lee P, Leonard JV, Chen YT. Mutations in exon 3 of the glycogen debranching enzyme gene are associated with glycogen storage disease type III that is differentially expressed in liver and muscle. J Clin Invest 98(2):352-7, 7/1996. PMCID: PMC507437.

Last updated: 8/14/2009