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Johannes E. Wolff, M.D.

Present Title & Affiliation

Primary Appointment

Head, Section of Pediatric Neuro-Oncology, Children's Cancer Hospital, The University of Texas M. D. Anderson Cancer Center, Houston, TX
Professor (tenure track), Department of Pediatrics Patient Care, Division of Pediatrics, The University of Texas M. D. Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Professor, Department of Biostatistics, Division of Quantitative Sciences, The University of Texas M. D. Anderson Cancer Center, Houston, TX
Faculty, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX

Education & Training

Degree-Granting Education

1987 University of Bochum, Bochum, Germany, Dr. med., Medicine
1986 University of Mainz, Mainz, Germany, MD, Medicine
1981 University of Bochum, Bochum, Germany, BS, Medical Science

Board Certifications

2004 Pediatric Hematology/Oncology Board, Bayerische Ärztekammer, State of Bavaria, Germany
2004 Venia legendi: University of Regensburg, Germany
1994 Venia legendi, Dr. med habil: University of Münster, Germany
1993 Pediatric Board: College of Physicians and Surgeons, Ärztekammer Westfalen-Lippe, Germany

Experience/Service

Other Appointments/Responsibilities

Medical Staff, Memorial Hermann Hospital, Houston, TX, 2006-present

Selected Publications

Peer-Reviewed Original Research Articles
1. Amini E, Roffidal T, Lee A, Fuller GN, Mahajan A, Ketonen L, Kobrinsky N, Cairo MS, Wells RJ, Wolff JE. Central neurocytoma responsive to topotecan, ifosfamide, carboplatin. Pediatr Blood Cancer 51(1):137-40, 7/2008. PMID: 18338396.
2. Wolff JE, Berrak S, Koontz Webb SE, Zhang M. Nitrosourea efficacy in high-grade glioma: A survival gain analysis summarizing 504 cohorts with 24193 patients. J Neurooncol 88(1):57-63, 5/2008. PMID: 18253699.
3. De Vleeschouwer S, Fieuws S, Rutkowski S, Van Calenbergh F, Van Loon J, Goffin J, Sciot R, Wilms G, Demaerel P, Warmuth-Metz M, Soerensen N, Wolff JE, Wagner S, Kaempgen E, Van Gool SW. Postoperative adjuvant dendritic cell-based immunotherapy in patients with relapsed glioblastoma multiforme. Clin Cancer Res 14(10):3098-104, 5/2008. PMID: 18483377.
4. Wolff JE, Classen CF, Wagner S, Kortmann RD, Palla SL, Pietsch T, Kühl J, Gnekow A, Kramm CM. Subpopulations of malignant gliomas in pediatric patients: Analysis of the HIT-GBM database. J Neurooncol 87(2):155-64, 4/2008. PMID: 18209954.
5. Nupponen NN, Paulsson J, Jeibmann A, Wrede B, Tanner M, Wolff JE, Paulus W, Ostman A, Hasselblatt M. Platelet-derived growth factor receptor expression and amplification in choroid plexus carcinomas. Mod Pathol 21(3):265-70, 3/2008. PMID: 18157090.
6. Zhang M, Segerer F, Ketonen L, Mahajan A, Wolff J. Prediction of tumour regrowth of pontine glioma using a two-term model. Anticancer Res 28(2A):741-9, Mar-Apr, 3/2008. PMID: 18507015.
7. Wagner S, Peters O, Fels C, Janssen G, Liebeskind AK, Sauerbrey A, Suttorp M, Hau P, Wolff JE. Pegylated-liposomal doxorubicin and oral topotecan in eight children with relapsed high-grade malignant brain tumors. J Neurooncol 86(2):175-81, 1/2008. PMID: 17641821.

Invited Articles
1. Wolff J, Wolff B. Quality of death in children: where is it higher--at home or in the hospital? Pediatr Blood Cancer 50(5):945-6, 5/2008. PMID: 18273872.
Other Articles
1. Wrede B, Wolff J, Peters O. Choroid Plexus Tumor Meeting, 39th SIOP Congress in Mumbai, India, October 2007: SIOP News(36):31-32, 1/2008.

Abstracts
1. Hassleblat M, Muehlisch J, Wrede B, Kallinger B, Jeilbann A, Peters O, Wolff J, and Paulus W. Aberrant MGMT(O-Methyguanine-DNA methyltransferase)Promoter methylation is a frequent event in choroid plexus tumor. Neuro-Oncology, 6/2008.
2. Wrede B, Peters O, Thall PF, Ebetsberger G, Natharath M, Jorch N, Hasselblatt M, Canete A, Wolff j. Clinical features of the new who entity of atypical choroid plexus papiloma: a subgroup analysis of the international randomized cpt-siop-2000 study. Neuro-Oncology, 6/2008.
3. Wolff JEA, Wrede B, Kutluk T, Moghrabi A, Peters O. CPT-SIOP-2000 study: A planet-wide choroid plexus tumor study - interim report. The 17th International Conference on Brain Tumor Research and Therapy, Japan, 6/2008.
4. Berrak S, Wrede B, Wolff J. Etoposide improves survival in choroid plexus, carcinoma:results of a meta-analysis. Neuro-Oncology, 6/2008.
5. Peters O, Heinzelmann B, Marienhagen J, Friedrich M, Ulrich OW, Pietsch T, Rolf-Dieter K, Warmuth-Metz M, Wrede B, Turowski P, Demleitnew G, Wolff J. German Pediatric Atypical Teratoid/RHABDOID tumors: Interim analysis of the ATRT-CNS pilot study and retrospective analysis. Neuro-Oncology, 6/2008.
6. Van Gool S, Rutowski S, Kaempgen E, Wolff J, Wagner S, Van Calenberg F, Kramm C, Ardon H, De Vleeschouwer S. Immunotherapy for relapsed high-grade glimoma: clinical update of cohorts a,b,c and d from the cohort comparison trial hgg-immuno-2003. Neuro-Oncology, 6/2008.
7. Hasselblatt M, Mersch S, Heibmann A, Riemeier B, Stegemann H, Wrede B, Wolff J, and Paulus W. Magic angle spinning metabolite profiles characterize glial and primitive neuroectodermal tumors. Neuro-Oncology, 6/2008.

Letters to the Editor
1. Masoudi A, Amini E, Wolff JE, Fuller GN, Ketonen L, Mahajan A. Shrinkage of germinoma by dexamethasone only. Pediatr Blood Cancer 50(5):1079, 5/2008. PMID: 18000859.

Last updated: 7/15/2009