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Lawrence E Ginsberg, M.D.

Present Title & Affiliation

Dual/Joint/Adjunct Appointment

Professor, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX

Bio Statement

Dr. Ginsberg is a Professor of Radiology in the Department of Diagnostic Radiology and Head and Neck Surgery at The University of Texas MD Anderson Cancer Center, Houston, TX. He was an undergraduate of State University of New York, Stony Brook, New York – received a B.A. Chemistry 1974-1978.

Dr. Ginsberg graduated from University of Health Sciences The Chicago Medical School North Chicago, Ill – M.D. 1978-1982. He has been on the MD Anderson faculty since 1994.

Dr. Ginsberg has given over 300 lectures/presentations and has written over 150 publications and articles in refereed journals, with numerous letters/commentaries and editorials.

Dr. Ginsberg also holds an adjunct appointment with Baylor College of Medicine. He holds conferences every week for the trainees to attend and learn head and neck imaging. When they rotate through Neuroradiology their first request is to be allowed to learn with Dr. Ginsberg in his reading room.

Dr. Ginsberg is a past president of the American Society of Head and Neck Neuroradiology. He was the program chair and organized the 44th Annual Meeting for this society that was hosted in Houston, Texas in 2010.

Research Interests

Research interests center on imaging following treatment of head and neck cancer, including efficacy, diagnosis of recurrences, and treatment-related complications. Also interested in imaging of perineural tumor spread, and pitfalls in the imaging of head and neck malignancy.

Clinical Interests

Head and neck cancer, imaging of perineural tumor spread, and pitfalls in the imaging of head and neck malignancy.

Education & Training

Degree-Granting Education

1982 Rosalind Franklin University of Medicine and Science, Chicago Medical School of North Chicago, Chicago, IL, MD, Medicine
1978 State University of New York, Stony Brook, NY, BA, Chemistry

Postgraduate Training

1986-1988 Clinical Fellowship, Neuroradiology, New York Hospital, Cornell Medical Center and Memorial Sloan-Kettering Cancer Center, New York, NY, Michael D. F. Deck, M.D.
1983-1986 Clinical Residency, Diagnostic Radiology, Columbia-Presbyterian Medical Center, New York, NY, David H. Baker, M.D.
1982-1983 Clinical Internship, Internal Medicine, Nassau County Medical Center, East Meadow, NY

Board Certifications

2005 Maintenance of Certification in Neuroradiology
1995 Certificate of Added Qualifications in Neuroradiology
1987 American Board of Radiology

Experience/Service

Institutional Committee Activities

Member, Diagnostic Imaging PET/CT Credential and Privileging Committee, 2013-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Rosenthal DI, Mohamed AS, Weber RS, Garden AS, Sevak PR, Kies MS, Morrison WH, Lewin JS, El-Naggar AK, Ginsberg LE, Kocak-Uzel E, Ang KK, Fuller CD. Long-term outcomes after surgical or nonsurgical initial therapy for patients with T4 squamous cell carcinoma of the larynx: A 3-decade survey. Cancer. e-Pub 1/2015. PMID: 25586197.
2. Millare GG, Hamilton JD, Ginsberg LE. Imaging Features of Intracranial Invasion of Nasopharyngeal Carcinoma via the Carotid Canal. Neurographics 4:183-188, 12/2014.
3. Ahmed S, Gupta N, Hamilton JD, Garden AS, Gidley PW, Ginsberg LE. CT Findings in Temporal Bone Osteoradionecrosis. J Comput Assist Tomogr 38(5):662-6, Sep-Oct, 9/2014. e-Pub 5/2014. PMCID: PMC4186743.
4. Cantrell SC, Reid HH, Li G, Wei Q, Sturgis EM, Ginsberg LE. Influence of Smoking History on Imaging Characteristics Among Patients With Human Papillomavirus-Positive Oropharyngeal Cancer: A Blinded Matched-Pair Analysis. J Comput Assist Tomogr 38(5):667-73, Sep-Oct, 9/2014. e-Pub 6/2014. PMCID: PMC4318505.
5. Saade R, Hessel A, Ginsberg L, Fuller G, Bell D. Primary extradural meningioma presenting as a neck mass: Case report and review of the literature. Head Neck. e-Pub 9/2014. PMID: 25251307.
6. Nader ME, Bell D, Sturgis EM, Ginsberg LE, Gidley PW. Facial nerve paralysis due to a pleomorphic adenoma with the imaging characteristics of a facial nerve schwannoma. J Neurol Surg Rep 75(1):e84-8, 8/2014. e-Pub 4/2014. PMCID: PMC4110139.
7. Hamilton JD, Rapp M, Schneiderhan T, Marcel Schneiderhan T, Sabel M, Hayman A, Scherer A, Kröpil P, Budach W, Gerber P, Kretschmar U, Arne Gerber P, Prabhu S, Ginsberg LE, Bölke E, Matuschek C. Glioblastoma Multiforme Metastasis Outside the CNS: Three Case Reports and Possible Mechanisms of Escape. J Clin Oncol 32(22):e80-4, 8/2014. e-Pub 2/2014. PMID: 24567434.
8. Lee PS, Sedrak P, Guha-Thakurta N, Chang EI, Ginsberg LE, Esmaeli B, Debnam JM. Imaging findings of recurrent tumors after orbital exenteration and free flap reconstruction. Ophthal Plast Reconstr Surg 30(4):315-21, Jul-Aug, 7/2014. e-Pub 5/2014. PMID: 24867414.
9. Sedrak P, Lee PS, Guha-Thakurta N, Chang EI, Ginsberg LE, Esmaeli B, Debnam JM. MRI Findings of Myocutaneous and Fasciocutaneous Flaps Used for Reconstruction of Orbital Exenteration Defects. Ophthal Plast Reconstr Surg 30(4):328-36, Jul-Aug, 7/2014. e-Pub 4/2014. PMID: 24777262.
10. Cantrell SC, Peck BW, Li G, Wei Q, Sturgis EM, Ginsberg LE. Differences in Imaging Characteristics of HPV-Positive and HPV-Negative Oropharyngeal Cancers: A Blinded Matched-Pair Analysis. AJNR Am J Neuroradiol 34(10):2005-2009, 10/2013. e-Pub 5/2013. PMCID: PMC3951375.
11. Hamilton JD, Ahmed S, Sandulache VC, Daram SP, Ow TJ, Skinner HD, Rao A, Ginsberg LE, Kumar AJ, Myers JN. Improving Imaging Diagnosis of Persistent Nodal Metastases after Definitive Therapy for Oropharyngeal Carcinoma: Specific Signs for CT and Best Performance of Combined Criteria. AJNR Am J Neuroradiol 34(8):1637-42, 8/2013. e-Pub 3/2013. PMCID: PMC3939678.
12. Kumar VA, Shah KB, Ginsberg LE. Perineural Tumor Spread to the Oculomotor (CN III) Nerve. J Comput Assist Tomogr 37(4):525-7, Jul-Aug, 7/2013. PMID: 23863527.
13. Pickering CR, Shah K, Ahmed S, Rao A, Frederick MJ, Zhang J, Unruh AK, Wang J, Ginsberg LE, Kumar AJ, Myers JN, Hamilton JD. CT Imaging Correlates of Genomic Expression for Oral Cavity Squamous Cell Carcinoma. AJNR Am J Neuroradiol. e-Pub 6/2013. PMID: 23764725.
14. Shah K, Esmaeli B, Ginsberg LE. Perineural tumor spread along the nasociliary branch of the ophthalmic nerve: imaging findings. J Comput Assist Tomogr 37(2):282-5, Mar-Apr, 3/2013. PMID: 23493220.
15. Singh S, Rosenthal DI, Ginsberg LE. Enlargement and transformation of thyroglossal duct cysts in response to radiotherapy: imaging findings. AJNR Am J Neuroradiol 30(4):800-802, 4/2009. e-Pub 1/2009. PMID: 19131415.
16. Ma J, Jackson EF, Kumar AJ, Ginsberg LE. Improving fat-suppressed T2-weighted imaging of the head and neck with two fast spin-echo Dixon techniques: initial experiences. AJNR Am J Neuroradiol 30(1):42-45, 1/2009. e-Pub 7/2008. PMID: 18653688.
17. La Barge DV, Salzman KL, Harnsberger HR, Ginsberg LE, Hamilton BE, Wiggins RH, Hudgins PA. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) imaging manifestations in the head and neck. AJR Am J Roentgenol 191(6):299-306, 12/2008. PMID: 19020219.
18. Dong F, Gidley PW, Ho T, Luna MA, Ginsberg LE, Sturgis EM. Adenoid cystic carcinoma of the external auditory canal. Laryngoscope 118(9):1591-1596, 9/2008. PMID: 18677277.
19. Debnam JM, Garden AS, Ginsberg LE. Benign ulceration as a manifestation of soft tissue radiation necrosis: imaging findings. AJNR Am J Neuroradiol 29(3):558-562, 3/2008. e-Pub 1/2008. PMID: 18202241.
20. Debnam JM, Esmaeli B, Ginsberg LE. Imaging characteristics of dacryocystocele diagnosed after surgery for sinonasal cancer. AJNR Am J Neuroradiol 28(10):1872-1875, Nov-Dec, 2007. PMID: 17921234.
21. Shellenberger T, Fornage B, Ginsberg LE, Clayman GL. Transoral resection of thyroid cancer metastasis to lateral retropharyngeal nodes. Head Neck 29(3):258-266, 2007.
22. Kumar VA, Lewin JS, Ginsberg LE. CT assessment of vocal cord medialization. AJNR Am J Neuroradiol 27(8):1643-1646, Nov-Dec, 2006. PMID: 16971603.
23. Cody DD, Stevens DM, Ginsberg LE. Multi-detector row CT artifacts that mimic disease. Radiology 236(3):756-761, 2005. PMID: 16055698.
24. Hentschel SJ, McCutheon IE,Ginsberg LE, Weinberg JS. Exophytic ependymomas of the spinal cord. A report of two cases. ACTA Neurochir 146:1047-1050, 2004.

Invited Articles

1. Ginsberg LE. MR imaging of perineural tumor spread. Neuroimaging Clin N Am 14(4):663-677, 2004. PMID: 15489147.

Abstracts

1. Ginsberg LE. Head and Neck Cancer: What the Radiologist Provides. Proceedings book of the 23rd Annual Meeting of the International Society of Magnetic Resonance in Medicine, 5/2015.
2. Ginsberg LE. Imaging in Oropharyngeal and Oral Cavity Cancer. Proceedings Book of 2nd Annual Head & Neck Oncology: A Mult-Disciplinary Approach, 5/2015.
3. Ginsberg LE. Imaging of Cutaneous Malignancy. Proceedings Book of 2nd Annual Head & Neck Oncology: A Mult-Disciplinary Approach, 5/2015.
4. Ginsberg LE. Imaging of Perineural Tumor Spread in Head and Neck Cancer. Proceedings Book of 2nd Annual Head & Neck Oncology: A Mult-Disciplinary Approach, 5/2015.
5. Ginsberg LE||B. Imaging Update in HPV-related Head & Neck Cancer. Proceedings Book of 2nd Annual Head & Neck Oncology: A Mult-Disciplinary Approach, 5/2015.
6. Tumu A, Ginsberg LE. Don't Blow It: Pneumoparotid related to overzealous distension of the oral cavity during puffed-cheek CT scans. Proceedings book of the 53rd annual ASNR meeting, 4/2015.
7. Ginsberg LE. Get Off My Nerves: Perineural Neoplasia. Proceedings book of the 53rd annual ASNR meeting, 4/2015.
8. Ginsberg LE. Imaging the post-treatment head and neck cancer patient: Pitfalls and potential. Proceedings book of the 53rd annual ASNR meeting, 4/2015.
9. Shah K, Ginsberg LE. Parotid region tumor recurrence associated with greater auricular perineural tumor spread and intraspinal extension along multiple cervical nerve roots. Proceedings book of the 53rd annual ASNR meeting, 4/2015.
10. Alsarraf L, Kumar VA, Zafereo, Ahmed S, Ginsberg LE. Laryngeal Amyloidosis:Unique imaging features. Proceedings book of the Annual American Society of Head and Neck Radiology 48th annual meeting, 9/2014.
11. Wangaryattawanich P, Ginsberg LE. Thyroid Carcinoma with Macrovascular Invasion of the Cervical Veins: Case Series with an Imaging Perspective and Literature Review. Proceedings book of the Annual American Society of Head and Neck Radiology 48th annual meeting, 9/2014.
12. Cantrell S, Patel M, Shatzkes D, Ginsberg LE. Trigeminal Nerve Anatomy as Illustrated by Schwannoma. Proceedings book of the Annual American Society of Head and Neck Radiology 48th annual meeting, 9/2014.
13. Cantrell S, Bell D, Ginsberg LE. Extraspinal Meningioma Presenting as a Neck Mass. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting (#EE-61), 5/2014.
14. Alsarraf L, Shah KB, Hessel A, Williams M, Ginsberg LE. Imaging of Supraclavicular Nerve Perineural Spread with Operative Correlation. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting, 5/2014.
15. Wang B, Ginsberg LE. Osseous Metaplasia of the Laryngeal Cartilage Mimicking Tumor Invasion. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting (#EE-69), 5/2014.
16. Dunaway D, Gidley P, Brown P, Ginsberg LE, Ahmed S. Perineural Spread of Adenoid Cystic Carcinoma Mimicking a Cavernous Sinus Meningioma. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting (#EE-48), 5/2014.
17. Ginsberg LE. Update on HPV-associated oropharyngeal malignancy. Proceedings Book of the Annual American Society of Neuroradiology 52nd Meeting, 5/2014.
18. Ahmed S, Gupta N, Hamilton J, Garden A, Gidley P, Ginsberg LE. CT Findings for Diagnosis and Complications of Temporal Bone Osteoradionecrosis. Proceedings book of the Annual American Society of Head and Neck Radiology 47th meeting, 9/2013.
19. Ginsberg LE. Imaging evaluation of the patient with a new neck node. Proceedings book of the Annual American Society of Head and Neck Radiology 47th meeting, 9/2013.
20. Kumar S, Ginsberg LE. Bilateral Inferior Alveolar Nerve Enlargement. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting (#EE-41), 5/2013.
21. Ahmed S, Gupta N, Hamilton J, Garden A, Gidley P, Ginsberg LE. CT Findings for Diagnosis and Complications of Temporal Bone Osteoradionecrosis. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting (#O-537), 5/2013.
22. Ahmed S, Jones J, Steele J, Sandulache VC, Ow TJ, Skinner HD, Rao A, Ginsberg LE, Kumar AJ, Myers JN, Hamilton JD. Estimates of Clinical Cost Savings for New, Better Performing Criteria for Diagnosis of Persistent Nodal Metastases after Treatment for Oropharyngeal Carcinoma. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting (#O-485), 5/2013.
23. Ginsberg LE. Imaging of HPV-Related Oropharyngeal Cancer. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting (#O-374), 5/2013.
24. Sedrak P, Lee PS, Guha-Thakurta N, Chang EI, <b>Ginsberg LE</b>, Esmaeli B, Debnam JM. MR Imaging of Fasciocutaneous and Myocutaneous Flap Reconstruction following Orbital Exenteration. Proceedings Book of the Annual American Society of Neuroradiology 51st Meeting (#P-79), 5/2013.
25. Ginsberg LE. A phase I dose escalation study of pemetrexed in patients with advanced head and neck squamous cell cancer (HNSCC). American Society Therapeutic Radiology and Oncology: 49th Annual Meeting, 2007.
26. Ginsberg LE. Phase II study of combination cisplatin, docetaxel and erlotinib in patients with metastatic/recurrent head and neck squamous cell carcinoma (HNSCC). American Society of Therapeutic Radiology and Oncology: 49th Annual Meeting, 2007.

Book Chapters

1. Ginsberg LE. Perineural tumor spread associated with head and neck malignancies. In: Head and Neck Imaging, 5th. Ed(s) Peter M. Som, Hugh D. Curtin. Mosby: St. Louis, MO, 1021-1049, 2011.
2. Ginsberg LE. Imaging of skull base neoplasms. In: Comprehensive Management of Skull Base Tumors. Ed(s) Ehab Y. Hanna, Franco Demonte. Informa Healthcare: New York, 81-93, 2009.
3. Ginsberg LE. The role of diagnostic imaging in identifying cervical metastases in oral cavity cancer. In: Oral Cancer Metastasis. Ed(s) Jeffrey Myers. Springer Link, 33-48, 2009.
4. Ginsberg LE. Oral cavity and oropharyngeal cancer. In: Squamous Cell Cancer of the Neck. Ed(s) Robert Hermans. Cambridge University Press, 67-93, 2008.
5. Kies MS, Lewin J, Ginsberg LE, Lippman SM. Head and neck cancer. In: The MD Anderson Manual of Clinical Oncology. Ed(s) Hagop M. Kantarjian, Robert A. Wolff, Charles A. Koller. McGraw-Hill: New York, 2006.
6. Ginsberg LE, Chen MYM, Pope TL Jr, Ott DJ. Imagen de la columna vertebral. In: Radiologia Basica. McGraw-Hill Interameicana De Espana, S.A.U. Madrid, Spain, 393-416, 2006.
7. Ginsberg LE. Imaging of the spine. In: Basic Radiology. Ed(s) Michael Y. M. Chen, Thomas Lee Pope, David J. Ott. Lange Medical Books/McGraw-Hill: New York, 352-373, 2004.

Letters to the Editor

1. Ginsberg LE. Radiologists as physicians. Radiology 250(2):605-606, 2/2009. PMID: 19188332.
2. Ginsberg LE. PowerPoint pen. AJR Am J Roentgenol 182(1):258, 2004. PMID: 14684549.

Last updated: 8/20/2015