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Marilyn Stovall, Ph.D.

Present Title & Affiliation

Primary Appointment

Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Bio Statement

 I have 59-years of experience in radiation late effects and have collaborated with the Radiation Epidemiology Branch at the National Cancer Institute for more than 30 years. I am the director of the Late Effects Studies Group at MD Anderson Cancer Center. Our research focuses on epidemiological studies of the late effects of radiation in humans. We participate in large national and international studies of radiation as a risk factor for tumor induction, organ dysfunction, genetic damage, and other late effects of radiation exposure. Populations include patients irradiated for therapy of malignant and benign tumors and for diagnostic tests, as well as medical workers occupationally exposed to radiation. To date, records for more than 100,000 patients from 350 institutions have been processed. These patients were irradiated as long ago as 1916, although most were irradiated from the 1930s to the 1990s. 

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd
Unit Number: 605
Houston, TX 77030
Room Number: ERD1.201

Education & Training

Degree-Granting Education

1996 University of Texas Health Science Center at Houston, School of Public Health, Houston, TX, PHD, Epidemiology
1979 University of Texas Health Science Center at Houston, School of Public Health, Houston, TX, MPH, Public Health
1951 Baylor University, Waco, TX, BS, Zoology & Mathematics

Experience/Service

Academic Appointments

Physics Technician, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/1951-8/1956

Honors and Awards

2013 Failla Memorial Award, Radiation Research Society
2013 Marvin M. D. Williams Professional Achievement Award, American Association of Physicists in Medicine
2007 Achievement in Medical Physics, American Association of Physicists in Medicine
2004 ACMP Fellow, American College of Medical Physics
1999 J.D.Land Clinical Society Award
1997 AAPM Fellow, American Association of Physicists in Medicine
1993 Robert J. Shalek Award, Southwest Chapter AAPM

Professional Memberships

MD Anderson Cancer Center, Houston, TX
Research Faculty Member, Survivorship Support & Outreach Subcommittee, 2010-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Whelan KF, Stratton K, Kawashima T, Waterbor JW, Castleberry RP, Stovall M, Sklar CA, Packer RJ, Mitby P, Aitken CL, Blatt J, Robison LL, Mertens AC. Ocular late effects in childhood and adolescent cancer survivors: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer 54(1):103-9, 1/2010. e-Pub 9/2009. PMCID: PMC2783513.
2. Ellenberg L, Liu Q, Gioia G, Yasui Y, Packer RJ, Mertens A, Donaldson SS, Stovall M, Kadan-Lottick N, Armstrong G, Robison LL, Zeltzer LK. Neurocognitive status in long-term survivors of childhood CNS malignancies: a report from the Childhood Cancer Survivor Study. Neuropsychology 23(6):705-17, 11/2009. PMCID: PMC2796110.
3. Sigurdson AJ, Bhatti P, Chang SC, Rajaraman P, Doody MM, Bowen L, Simon SL, Weinstock RM, Linet MS, Rosenstein M, Stovall M, Alexander BH, Preston DL, Struewing JP. Polymorphisms in estrogen biosynthesis and metabolism-related genes, ionizing radiation exposure, and risk of breast cancer among US radiologic technologists. Breast Cancer Res Treat 118(1):177-84, 11/2009. e-Pub 2/12/2009. PMID: 19214745.
4. Chodick G, Kleinerman RA, Stovall M, Abramson DH, Seddon JM, Smith SA, Tucker MA. Risk of cataract extraction among adult retinoblastoma survivors. Arch Ophthalmol 127(11):1500-4, 11/2009. PMID: 19901216.
5. Chow EJ, Friedman DL, Stovall M, Yasui Y, Whitton JA, Robison LL, Sklar CA. Risk of thyroid dysfunction and subsequent thyroid cancer among survivors of acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer 53(3):432-437, 9/2009. PMCID: PMC2713362.
6. Green DM, Kawashima T, Stovall M, Leisenring W, Sklar CA, Mertens AC, Donaldson SS, Byrne J, Robison LL. Fertility of Female Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. J Clin Oncol 27(16):2677-85, 06/01/2009, 4/2009. e-Pub 4/2009. PMCID: PMC2690392.
7. Kry SF, Salehpour M, Titt U, White RA, Stovall M, Followill D. Monte Carlo study shows no significant difference in second cancer risk between 6- and 18-MV intensity-modulated radiation therapy. Radiother Oncol 91(1):132-7, 4/2009. e-Pub 1/2009. PMID: 19147246.
8. Green DM, Sklar CA, Boice Jr, JD, Mulvihill JJ, Whitton JA, Stovall M, Yasui Y. Ovarian failure and reproductive outcomes after childhood cancer treatment: results from the Childhood Cancer Survivor Study. J Clin Oncol 27(14), http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2008.21.1839, 05/10/2009. e-Pub 4/2009. PMCID: PMC2677923.
9. Leisenring WM, Mertens AC, Armstrong GT, Stovall MA, Neglia JP, Lanctot JQ, Boice, Jr JD, Whitton JA, Yasui Y. Pediatric Cancer Survivorship Research: Experience of the Childhood Cancer Survivor Study. J Clin Oncol 27(14):2319-27, 05/10/2009, 4/2009. e-Pub 4/2009. PMID: 19364957.
10. Robison LL, Armstrong GT, Boice JD, Chow EJ, Davies SM, Donaldson SS, Green DM, Hammond S, Meadows AT, Mertens AC, Mulvihill JJ, Nathan PC, Neglia JP, Packer RJ, Rajaraman P, Sklar CA, Stovall M, Strong LC, Yasui Y, Zeltzer LK. The Childhood Cancer Survivor Study: A National Cancer Institute-Supported Resource for Outcome and Intervention Research. J Clin Oncol 27(14):2308-18, http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2009.22.3339, 05/10/2009, 4/2009. e-Pub 4/2009. PMCID: PMC2677920.
11. Armstrong GT, Whitton JA, Gajjar A, Kun LE, Chow EJ, Stovall M, Leisenring W, Robison LL, Sklar CA. Abnormal timing of menarche in survivors of central nervous system tumors: a report from the Childhood Cancer Survivor Study. Cancer 115(11):2562-70, 3/2009. e-Pub 3/2009. PMID: 19309737.
12. Meadows AT, Friedman DL, Neglia JP, Mertens AC, Donaldson SS, Stovall M, Hammond S, Yasui Y, Inskip PD. Second neoplasms in survivors of childhood cancer: findings from the Childhood Cancer Survivor Study Cohort. J Clin Oncol 27(14), 05/10/2009. e-Pub 3/2009. PMID: 19255307.
13. Knight JA, Bernstein L, Largent J, Capanu M, Begg CB, Mellemkjaer L, Lynch CF, Malone KE, Reiner AS, Liang X, Haile RW, Boice JD, WECARE Study Collaborative Group, Bernstein JL. Alcohol intake and cigarette smoking and risk of a contralateral breast cancer: The Women's Environmental Cancer and Radiation Epidemiology Study. Am J Epidemiol 169(8). e-Pub 2/2009. PMID: 19211621.
14. Yu CL, Tucker MA, Abramson DH, Furukawa K, Seddon JM, Stovall M, Fraumeni JF, Kleinerman RA. Cause-specific mortality in long-term survivors of retinoblastoma. J Natl Cancer Inst 101(8):581-591, 04/15/2009, 2009. e-Pub 4/2009. PMCID: PMC2669101.
15. Winther JF, Boice JD, Frederiksen K, Bautz A, Mulvihill JJ, Stovall M, Olsen JH. Radiotherapy for childhood cancer and risk for congenital malformations in offspring: a population-based cohort study. Clin Genet 75(1):50-6, 2009. e-Pub 11/2008. PMID: 19021636.
16. Langholz B, Thomas DC, Stovall M, Smith SA, Boice JD, Shore RE, Bernstein L, Lynch CF, Zhang X, Bernstein JL. Statistical Methods for Analysis of Radiation Effects with Tumor and Dose Location-Specific Information with Application to the WECARE Study of Asynchronous Contralateral Breast Cancer. Biometrics 65(2):599-608, 2008. e-Pub 7/2008. PMID: 18647297.
17. Kry SF, Titt U, Followill D, Ponisch F, Vassiliev ON, White RA, Stovall M, Salehpour M. A Monte Carlo model for out-of-field dose calculation from high-energy photon therapy. Med Phys 34(9):3489-3499, 09/34/2007, 9/2007.
18. Jenkinson HC, Winter DL, Marsden HB, Stovall MA, Stevens MC, Stiller CA, Hawkins MM. A study of soft tissue sarcomas after childhood cancer in Britain. Br J Cancer 97:695-699, 7/2007.
19. Kry SF, Followill D, White RA, Stovall M, Kuban DA, Salehpour M. Uncertainty of calculated risk estimates for secondary malignancies after radiotherapy. Int J Radiat Oncol Biol Phys 68(4):1265-71, 07/15/2007, 7/2007.
20. Borghero YO, Salehpour M, McNeese MD, Stovall M, Smith SA, Johnson J, Perkins GH, Strom EA, Oh JL, Kirsner SM, Woodward WA, Yu TK, Buchholz TA. Multileaf field-in-field forward-planned intensity-modulated dose compensation for whole-breast irradiation is associated with reduced contralateral breast dose: A phantom model comparison. Radiother Oncol 82:324-328, 3/2007. PMID: 17157944.
21. Signorello LB, Cohen SS, Bosetti C, Stovall M, Kasper CE, Weathers RE, Whitton JA, Green DM, Donaldson SS, Mertens AC, Robison LL, Boice JD, Jr. Female survivors of childhood cancer: preterm birth and low birth weight among their children. J Natl Cancer Inst 98:1453-61, 10/2006. PMID: 17047194.
22. Ronckers CM, Sigurdson AJ, Stovall M, Smith SA, Mertens AC, Liu Y, Hammond S, Land CE, Neglia JP, Donaldson SS, Meadows AT, Sklar CA, Robison LL, Inskip PD. Thyroid cancer in childhood cancer survivors: a detailed evaluation of radiation dose response and its modifiers. Radiat Res 166:618-28, 10/2006. PMID: 17007558.
23. Stovall M, Weathers R, Kasper C, Smith SA, Travis L, Ron E, Kleinerman R. Dose reconstruction for therapeutic and diagnostic radiation exposures: use in epidemiological studies. Radiat Res 166:141-57, 7/2006. PMID: 16808603.
24. Sklar CA, Mertens AC, Mitby P, Whitton J, Stovall M, Kasper C, Mulder J, Green D, Nicholson HS, Yasui Y, Robison LL. Premature menopause in survivors of childhood cancer: a report from the childhood cancer survivor study. J Natl Cancer Inst 98:890-6, 7/2006. PMID: 16818852.
25. Chemaitilly W, Mertens AC, Mitby P, Whitton J, Stovall M, Yasui Y, Robison LL, Sklar CA. Acute ovarian failure in the Childhood Cancer Survivor Study. J Clin Endocrinol Metab 91:1723-8, 5/2006. PMID: 16492690.
26. Rees GS, Trikic MZ, Winther JF, Tawn EJ, Stovall M, Olsen JH, Rechnitzer C, Schroder H, Guldberg P, Boice JD, Jr. A pilot study examining germline minisatellite mutations in the offspring of Danish childhood and adolescent cancer survivors treated with radiotherapy. Int J Radiat Biol 82:153-60, 3/2006. PMID: 16638712.
27. Bassal M, Mertens AC, Taylor L, Neglia JP, Greffe BS, Hammond S, Ronckers CM, Friedman DL, Stovall M, Yasui YY, Robison LL, Meadows AT, Kadan-Lottick NS. Risk of selected subsequent carcinomas in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Clin Oncol 24:476-83, 1/2006. PMID: 16421424.
28. Kry SF, Salehpour M, Followill DS, Stovall M, Kuban DA, White RA, Rosen,, II. Out-of-field photon and neutron dose equivalents from step-and-shoot intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 62(4):1204-16, 07/15/2005, 7/2005. PMID: 15990026.
29. Kry SF, Salehpour M, Followill DS, Stovall M, Kuban DA, White RA, Rosen,, II. The calculated risk of fatal secondary malignancies from intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 62(4):1195-203, 07/15/2005, 7/2005. PMID: 15990025.
30. Brownstein CM, Mertens AC, Mitby PA, Stovall M, Qin J, Heller G, Robison LL, Sklar CA. Factors that affect final height and change in height standard deviation scores in survivors of childhood cancer treated with growth hormone: a report from the childhood cancer survivor study. J Clin Endocrinol Metab 89(9):4422-7, 9/2004. PMID: 15356041.
31. Bernstein JL, Langholz B, Haile RW, Bernstein L, Thomas DC, Stovall M, Malone KE, Lynch CF, Olsen JH, Anton-Culver H, Shore RE, Boice JD, Jr, Berkowitz GS, Gatti RA, Teitelbaum SL, Smith SA, Rosenstein BS, Borresen-Dale AL, Concannon P, Thompson WD. Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study. Breast Cancer Res 6(3):R199-214, 2004. PMID: 15084244.
32. Gurney JG, Ness KK, Stovall M, Wolden S, Punyko JA, Neglia JP, Mertens AC, Packer RJ, Robison LL, Sklar CA. Final height and body mass index among adult survivors of childhood brain cancer: Childhood Cancer Survivor Study. J Clin Endocrinol Metab 88(10):4731-9, 10/2003. PMID: 14557448.
33. Packer RJ, Gurney JG, Punyko JA, Donaldson SS, Inskip PD, Stovall M, Yasui Y, Mertens AC, Sklar CA, Nicholson HS, Zeltzer LK, Neglia JP, Robison LL. Long-term neurologic and neurosensory sequelae in adult survivors of a childhood brain tumor: Childhood Cancer Survivor Study. J Clin Oncol 21(17):3255-61, 9/2003. PMID: 12947060.
34. Travis LB, Hill DA, Dores GM, Gospodarowicz M, van Leeuwen FE, Holowaty E, Glimelius B, Andersson M, Wiklund T, Lynch CF, Van't Veer MB, Glimelius I, Storm H, Pukkala E, Stovall M, Curtis R, Boice JD, Jr, Gilbert E. Breast cancer following radiotherapy and chemotherapy among young women with Hodgkin disease. Jama 290(4):465-75, 7/2003. PMID: 12876089.
35. Boice JD, Jr, Tawn EJ, Winther JF, Donaldson SS, Green DM, Mertens AC, Mulvihill JJ, Olsen JH, Robison LL, Stovall M. Genetic effects of radiotherapy for childhood cancer. Health Phys 85(1):65-80, 7/2003. PMID: 12852473.
36. Oeffinger KC, Mertens AC, Sklar CA, Yasui Y, Fears T, Stovall M, Vik TA, Inskip PD, Robison LL. Obesity in adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. J Clin Oncol 21(7):1359-65, 4/2003. PMID: 12663727.
37. Followill DS, Stovall MS, Kry SF, Ibbott GS. Neutron source strength measurements for Varian, Siemens, Elekta, and General Electric linear accelerators. J Appl Clin Med Phys 4(3):189-94, Summer 2003, 2003. PMID: 12841788.
38. Stovall M, Blackwell CR, Cundiff J, Novack DH, Palta JR, Wagner LK, Webster EW, Shalek RJ. Fetal dose from radiotherapy with photon beams: report of AAPM Radiation Therapy Committee Task Group No. 36. Med Phys 22(1):63-82, 1995. PMID: 7715571.
39. Stovall M, Smith SA, Rosenstein M. Tissue doses from radiotherapy of cancer of the uterine cervix. Med Phys 16(5):726-33, 9/1989. PMID: 2509867.
40. Ron E, Modan B, Boice JD, Jr, Alfandary E, Stovall M, Chetrit A, Katz L. Tumors of the brain and nervous system after radiotherapy in childhood. N Engl J Med 319(16):1033-9, 10/1988. PMID: 3173432.
41. Stovall M, Shalek RJ. The M. D. Anderson method for the computation of isodose curves around interstitial and intracavitary radiation sources. 3. Roentgenograms for input data and relation of isodose calculations to the Paterson-Parker system. Am J Roentgenol Radium Ther Nucl Med 102(3):677-87, 3/1968. PMID: 5639583.
42. Stovall M. Use of small sealed sources in radiotherapy. Radiology 88(1):154-6, 1967. PMID: 6015612.
43. Stovall M, Shalek RJ. A study of the explicit distribution of radiation in interstitial implantations. I. A method of calculation with an automatic digital computer. Radiology 78:950-4, 6/1962. PMID: 13917567.

Abstracts

1. Pappo AS, Armstrong GT, Liu W, Srivastava DK, Leisenring W, Hammond S, Stovall M, Neglia JP, Robison LL. Melanoma as a subsequent neoplasm in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. J Clin Oncol 29(suppl; abstr 9510) (#9510), 2011, 2011.

Grant & Contract Support

Title: Childhood Cancer Survivor Study
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Les Robison
Duration: 12/1/2011 - 11/30/2016
 
Title: Support Services for Medical Radiation Dosimetry For Epidemiology Studies
Funding Source: NIH/NCI
Role: Principal Investigator
Duration: 4/15/2010 - 4/14/2015
 
Title: Genome-Wide Association Study of Radiation and Bilateral Breast Cancer
Funding Source: NIH/NCI
Role: Principal Investigator-MDACC
Duration: 3/1/2009 - 3/31/2014

Last updated: 5/5/2014