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Matthew M. Hanasono, M.D.

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Plastic Surgery, Division of Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX

Bio Statement

Matthew M. Hanasono, M.D. is an Assistant Professor of Plastic Surgery at The University of Texas M. D. Anderson Cancer Center.  He is Director of the Physician Assistant Program and Co-Director of Microsurgical Education within the Department of Plastic Surgery. He trained at Cornell and Columbia Universities as well as Stanford University and is board certified in both Plastic Surgery and Otolaryngology-Head & Neck Surgery.  He also completed a fellowship in Microvascular Reconstructive Surgery at The University of Texas M. D. Anderson Cancer Center.

Dr. Hanasono has lectured nationally and internationally on a broad range of topics related to plastic and reconstructive surgery and has authored over 30 peer-reviewed articles and 15 book chapters. 

Research Interests

Dr. Hanasono performs reconstructive surgery for patients with cancer involving all areas of the body.  His clincial interests include reconstructive surgery for patients with head and neck cancer, breast cancer, and cancer of the upper and lower extremities.  Within head and neck cancer, Dr. Hanasono specializes in complex reconstruction of the face, oral cavity, upper and lower jaws, and skull base, including the facial nerve.  Dr. Hanasono has performed hundreds of microvascular free flap surgeries for cancer patients.  He also performs reconstructions after removal of skin cancers, such as after Moh's surgery or surgery for melanoma.

Clinical Interests

Dr. Hanasono's research interests include outcomes and translational research involving microvascular surgery, reconstructive surgery of the head and neck, and reconstructive surgery of the breast.  Current projects include computer modeling for maxillary and mandibular reconstruction, skull base and facial nerve reconstruction, and "aesthetic" reconstruction with adipofascial free flaps and autologous fat grafts.

Office Address

The University of Texas M. D. Anderson Cancer Center
1515 Holcombe Blvd.
Unit Number: 443
Houston, TX 77030
Room Number: FC8.2000
Phone: (713) 794-1247
Fax: (713) 794-5492

Education & Training

Degree-Granting Education

1997 Stanford University, Stanford, CA, MD, Medicine
1992 University of California, Los Angeles, Los Angeles, CA, BS, Biology

Postgraduate Training

7/2004-6/2005 Clinical Fellowship, Reconstructive Microsurgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX, Dr. Howard N. Langstein
7/2002-6/2004 Clinical Residency, Plastic Surgery, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, NY, Dr. Robert T. Grant
7/1998-6/2002 Clinical Residency, Otolaryngology-Head and Neck Surgery, Stanford University Medical Center, Stanford, CA, Dr. Anna H. Messner
6/1997-6/1998 Internship, General Surgery, Stanford University Medical Center, Stanford, CA, Dr. Augusto Bastidas

Board Certifications

11/2006 American Board of Plastic Surgery
5/2003 American Board of Otolaryngology

Experience/Service

Administrative Appointments/Responsibilities

Co-Director of Microsurgery Education, Department of Plastic Surgery, Division of Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 2008-present
Director of Plastic Surgery Physician Assistant Programs, Department of Plastic Surgery, Division of Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 2005-present

Honors and Awards

2009 Who's Who in America
2007 America's Top Physicians, Consumers Research Council of America
2007 Top Doctors in Houston, H Texas Magazine
1992 Graduation Summa cum Laude

Professional Memberships

American Academy of Facial Plastic and Reconstructive Surgery
Member, 1999-present
American Academy of Otolaryngology, Head and Neck Surgery
Member, 1998-present
American College of Surgeons
Fellow, 2008-present
American Society for Reconstructive Microsurgery
Member, 2006-present
American Society of Plastic Surgeons
Active Member, 2002-present
Houston Society of Plastic Surgeons
Member, 2006-present
Texas Medical Association
Member, 2005-present

Selected Publications

Peer-Reviewed Original Research Articles
1. Hanasono MM, Friel MT, Klem C, Hsu PW, Robb GL, Weber RS, Roberts DB, Chang DW. Impact of reconstructive microsurgery in patients with advanced oral cavity cancers. Head Neck. In Press. PMID: 19373778.
2. Moreno M, Skoracki RJ, Hanna EY, Hanasono MM. Microvascular free flap reconstruction versus palatal obturation for maxillectomy defects. Head Neck. In Press.
3. Yu P, Hanasono MM, Skoracki R, Baumann D, Lewin JS, Weber RS, Robb GL. Pharyngoesophageal reconstruction with the anterolateral thigh flap following total laryngopharyngectomy. Cancer. In Press.
4. Zafereo ME, Hanasono MM, Rosenthal D, Sturgis E, Roberts DB, Weber RS. Role of salvage surgery in patients with recurrent squamous cell carcinoma of the oropharynx. Cancer. In Press.
5. Hanasono MM, Skoracki RJ. The "omega-shaped" fibula flap for reconstruction of extensive mid-facial defects. Plast Reconstr Surg. In Press.
6. Hanasono MM, Ogunleye B, Yang JS, Hartley CJ, Miller MJ.. Changes in blood velocity following microvascular free tissue transfer. J Reconstr Microsurg 25(7):417-24, 9/2009. PMID: 19593731.
7. Hanasono MM, Barnea Y, Skoracki RJ. Microvascular surgery in the previously operated and irradiated neck. Microsurgery 29(1):1-7, 7/2009. PMID: 18942649.
8. Hanasono MM, Goel N, DeMonte F. Calvarial reconstruction with polyetheretherketone implants. Ann Plast Surg 62(6):653-5, 6/2009. PMID: 19461279.
9. Hanasono MW, Sacks JM, Goel N, Ayad M, Skoracki RJ. The anterolateral thigh free flap for skull base reconstruction. Otolaryngol Head Neck Surg 140(6):855-60, 6/2009. e-Pub 4/2009. PMID: 19467403.
10. Hanasono MM, Lee JC, Yang JS, Skoracki RJ, Reece GP, Esmaeli B.. An algorithmic approach to reconstructive surgery and prosthetic rehabilitation after orbital exenteration. Plast Reconstr Surg 123(1):98-105, 1/2009. PMID: 19116542.
11. Hanasono MM, Weinstock YE, Yu P. Reconstruction of extensive head and neck defects with multiple simultaneous free flaps. Plast Reconstr Surg 122(6):1739-46, 12/2008.
12. Hanasono MM, Lin SJ. Microvascular free tissue transfer of previously irradiated flaps. Otolaryngology-Head and Neck Surgery 139(2):320-22, 8/2008.
13. Hanasono MM, Butler CE. Prevention and treatment of thrombosis in microvascular surgery. Journal of Reconstructive Microsurgery 24(5):305-14, 7/2008.
14. Hanasono MM, Skoracki RJ. Securing skin grafts to microvascular free flaps using the vacuum-assisted closure (VAC) device. Ann Plast Surg 58:573-6, 5/2007.
15. Ascherman JA, Hanasono MM, Newman MI, Hughes DB. Implant reconstruction in breast cancer patients treated with radiation therapy. Plast Reconstr Surg 117:359-65, 2/2006. PMID: 16462313.
16. Hanasono MM, Osborne MP, Dielubanza EJ, Peters SB, Gayle LB. Radiation-induced angiosarcoma after mastectomy and TRAM flap breast reconstruction. Ann Plast Surg 54:211-4, 2/2005. PMID: 15655476.
17. Newman MI, Hanasono MM, Disa JJ, Cordeiro PG, Mehrara BJ. Scalp reconstruction: a 15-year experience. Ann Plast Surg 52:501-6; discussion 506, 5/2004. PMID: 15096938.
18. Hanasono MM, Parrett BM, Breitbart AS. Posttransplant lymphoproliferative disorder presenting as a cutaneous forehead mass. Otolaryngol Head Neck Surg 130:372-4, 3/2004. PMID: 15054384.
19. Hanasono MM, Lum J, Carroll LA, Mikulec AA, Koch RJ. The effect of silicone gel on basic fibroblast growth factor levels in fibroblast cell culture. Arch Facial Plast Surg 6:88-93, 3/2004. PMID: 15023795.
20. Lonergan DM, Mikulec AA, Hanasono MM, Kita M, Koch RJ. Growth factor profile of irradiated human dermal fibroblasts using a serum-free method. Plast Reconstr Surg 111:1960-8, 5/2003. PMID: 12711958.
21. Hanasono MM, Kita M, Mikulec AA, Lonergan D, Koch RJ. Autocrine growth factor production by fetal, keloid, and normal dermal fibroblasts. Arch Facial Plast Surg 5:26-30, 1/2003. PMID: 12533134.
22. Carroll LA, Hanasono MM, Mikulec AA, Kita M, Koch RJ. Triamcinolone stimulates bFGF production and inhibits TGF-beta1 production by human dermal fibroblasts. Dermatol Surg 28:704-9, 8/2002. PMID: 12174062.
23. Hanasono MM, Kridel RW, Pastorek NJ, Glasgold MJ, Koch RJ. Correction of the soft tissue pollybeak using triamcinolone injection. Arch Facial Plast Surg 4:26-30; discussion 31, 1/2002. PMID: 11843673.
24. Hanasono MM, Utley DS, Goode RL. The temporalis muscle flap for reconstruction after head and neck oncologic surgery. Laryngoscope 111:1719-25, 10/2001. PMID: 11801932.
25. Mikulec AA, Hanasono MM, Lum J, Kadleck JM, Kita M, Koch RJ. Effect of tamoxifen on transforming growth factor beta1 production by keloid and fetal fibroblasts. Arch Facial Plast Surg 3:111-4, 4/2001. PMID: 11368663.
26. Terris DJ, Hanasono MM, Liu YC. Reliability of the Muller maneuver and its association with sleep-disordered breathing. Laryngoscope 110:1819-23, 11/2000. PMID: 11081592.
27. Pollard JD, Hanasono MM, Mikulec AA, Le QT, Terris DJ. Head and neck cancer in cardiothoracic transplant recipients. Laryngoscope 110:1257-61, 8/2000. PMID: 10942122.
28. Moir MS, Samy RN, Hanasono MM, Terris DJ. Autologous and heterologous blood transfusion in head and neck cancer surgery. Arch Otolaryngol Head Neck Surg 125:864-8, 8/1999. PMID: 10448732.
29. Hanasono MM, Kunda LD, Segall GM, Ku GH, Terris DJ. Uses and limitations of FDG positron emission tomography in patients with head and neck cancer. Laryngoscope 109:880-5, 6/1999. PMID: 10369275.

Book Chapters
1. Beahm E, Hanasono MM, Shenaq S. Iliac Crest Flap. In: Atlas of Flaps and Microsurgical Techniques. Elsevier. In Press.
2. Hanasono MM, Lin SJ. Mandibular Reconstruction. In: Advanced Therapy in Facial and Plastic Reconstructive Surgery. BC Decker Inc. In Press.
3. Hsu A, Hanasono MM. Orbital Exenteration and Rehabilitation of Exenterated Socket. In: Ophthalmic Oncology. Springer. In Press.
4. Hanasono MM, Butler CE. Scalp and Calvarial Reconstruction. In: Plastic Surgery Indications and Practice. 1, Chapter 67. Ed(s) Guyuron B, Eriksson E, Persing JA, Chung KC, Disa J, Gosain A, Rubin P, Kinney B. Elsevier Inc. Edinburgh, 891-897, 2009.
5. Hanasono MM. Scalp and Forehead Reconstruction. In: Procedures in Reconstructive Surgery: Head and Neck Reconstructive Surgery. Ed(s) CE Butler, MD. Saunders Elsevier, 39-53, 2009.
6. Hanasono MM. Oral/Oropharyngeal Tumors: How to Reconstruct Anterior Mandibular Defects in Patients with Vascular Diseases? In: Pearls and Pitfalls in Head and Neck Surgery. Karger Publishers, 66-67, 2008.
7. Feledy JA, Hanasono MM, Robb GL. Reconstructive Surgery in the Cancer Patient. In: The M. D. Anderson Surgical Oncology Handbook, Fourth Edition. Ed(s) Feig B. Lippincott, Williams and Wilkins, 2006.

Grant & Contract Support

Title: Combining Three-Dimensional Surface and Radiographic Imaging with Rapid Prototype Modeling for Free Flap Reconstruction and Prosthetic Rehabilitation in Head and Neck Cancer Patients
Funding Source: Kyte Foundation
Role: Principal Investigator
Duration: 1/2009 - 12/2009
 
Title: GST polymorphisms and complications of head and neck flap reconstruction
Funding Source: American Academy of Facial Plastic and Reconstructive Surgery
Role: Collaborator
Principal Investigator: Jose Zevallos, MD
Duration: 7/2008 - 6/2009

Last updated: 9/24/2009