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Michael E. Kupferman, M.D., FACS

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Clinical Site Liaison, Banner-MD Anderson Cancer Center, The University of Texas MD Anderson Global Network, Gilbert, AZ
Clinical Consultant, The University of Texas MD Anderson Cancer Center Global Network, MD Anderson Physicians Network, Houston, TX

Research Interests

Transoral robotic surgery for oropharynx cancer

Targeting the tumor microenvironment in squamous cell carcinoma

Molecular mechanisms of metastasis in head and neck cancer

Clinical Interests

Minimally invasive skull base surgery

Transoral robotic surgery for oropharynx cancer

Malignant melanoma of the head and neck

Benign and malignant salivary gland tumors

Recurrent and metastatic thyroid cancer

Office Address

The University of Texas MD Anderson Cancer Center
1400 Pressler St.
Unit Number: 1445
Houston, TX 77030
Room Number: FCT10.6008
Phone: 713/794-1910
Fax: 713/794-4662

Education & Training

Degree-Granting Education

1999 University of Pennsylvania School of Medicine, Philadelphia, PA, MD, Medicine
1995 Yeshiva University, New York, NY, BA, Political Science, Biology

Postgraduate Training

7/2004-6/2006 Clinical Fellowship, Head & Neck Oncologic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
7/2004-6/2005 Research Fellowship, Head & Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
7/2000-6/2004 Clinical Residency, Otolaryngology-Head & Neck Surgery, University of Pennsylvania, Philadelphia, PA
7/1999-6/2000 Clinical Internship, Surgery, University of Pennsylvania, Philadelphia, PA

Board Certifications

4/2005 American Board of Otolaryngology

Honors and Awards

2014 Chris O'Brien Traveling Fellowship Award, American Head and Neck Society-Australia-New Zealand Head and Neck Society
2011-present Fellow of American College of Surgeons, American College of Surgeons
2011-2012 Faculty Teaching Award, Head and Neck Surgery Program, The University of Texas MD Anderson Cancer Center
2011 U. S. News Best Doctor Directory, U. S. News and World Report
2008-2012 Physician-Scientist Program, MD Anderson Cancer Center
2006 AACR-AstraZeneca Scholar-in-Training Award, AACR
2004-2006 National Institutes of Health Loan Repayment Program, NIH
1996 NIH Cancer Research Training Grant, NIH

Professional Memberships

American Academy of Otolaryngology-Head & Neck Surgery
Member, 1999-present
American College of Surgeons
Member, 2006-present
American Head and Neck Society, Los Angeles, CA
Research Committee member, 2006-2009
American Society for Radiation Oncology, Fairfax, VA
Program Committee Planning Member, 1/2009-present
American Society of Clinical Oncology
Member, 2005-present
North American Skull Base Society
Director at Large, 2013-2014
Member, 2007-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Takahashi Y, Kupferman ME (corresponding author), Bell D, Jiffar T, Lee JG, Xie TX, Li NW, Zhao M, Frederick MJ, Gelbard A, Myers JN, Hanna EY. Establishment and characterization of novel cell lines from sinonasal undifferentiated carcinoma. Clin Cancer Res 18(22):6178-6187, 11/2012. e-Pub 10/2012. PMCID: PMC3513379.
2. McHugh CH, Roberts DB, El-Naggar AK, Hanna EY, Garden AS, Kies MS, Weber RS, Kupferman ME. Prognostic factors in mucoepidermoid carcinoma of the salivary glands. Cancer 118(16):3928-36, 8/2012. e-Pub 12/2011. PMID: 22180391.
3. Bhayani MK, Yener M, El-Naggar A, Garden A, Hanna EY, Weber RS, Kupferman ME. Prognosis and risk factors for early-stage adenoid cystic carcinoma of the major salivary glands. Cancer 118(11):2872-8, 6/2012. e-Pub 10/2011. PMID: 22020577.
4. Zevallos JP, Jain KS, Roberts D, El-Naggar A, Hanna EY, Kupferman ME. Sinonasal malignancies in children: A 10-year, single-institutional review. Laryngoscope 121(9):2001-3, 9/2011. e-Pub 7/2011. PMID: 21739433.
5. Jiffar T, Yilmaz T, Lee J, Hanna E, El-Naggar A, Yu D, Myers JN, Kupferman ME. KISS1 mediates platinum sensitivity and metastasis suppression in head and neck squamous cell carcinoma. Oncogene 30(28):3163-3173, 7/2011. e-Pub 3/2011. PMCID: PMC3136629.
6. Kupferman ME, de la Garza GO, Santillan AA, Williams MD, Varghese BT, Huh W, Roberts D, Weber RS. Outcomes of pediatric patients with malignancies of the major salivary glands. Ann Surg Oncol 17(12):3301-3307, 12/2010. e-Pub 6/2010. PMID: 20585877.
7. Yilmaz T, Jiffar T, de la Garza G, Lin H, Milas Z, Takahashi Y, Hanna E, MacIntyre T, Brown JL, Myers JN, Kupferman ME. Therapeutic targeting of Trk suppresses tumor proliferation and enhances cisplantin activity in HNSCC. Cancer Biol Ther 10(6):644-653, 9/2010. e-Pub 9/2010. PMCID: PMC3230305.
8. Kupferman ME, Jiffar T, El-Naggar A, Yilmaz T, Zhou G, Xie T, Feng L, Wang J, Holsinger FC, Yu D, Myers JN. TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma. Oncogene 29(14):2047-2059, 4/2010. e-Pub 1/2010. PMCID: PMC3138334.

Grant & Contract Support

Title: Stromal Determinants of Lymphatic Metastasis in Head and Neck Cancer
Funding Source: Institutional Review Grant, The University of Texas MD Anderson Cancer Center
Role: Principal Investigator-MDACC
Duration: 9/1/2012 - 8/31/2015
 
Title: Critical Role of TrkB for Invasion and Metastasis in HNSCC
Funding Source: Physician-Scientist Program, MD Anderson Cancer Center
Role: Principal Investigator
Duration: 9/1/2011 - 8/31/2013
 
Title: Critical Role of TrkB for Invasion and Metastasis in Oral Cancer
Funding Source: NIH/NIDCR
Role: Principal Investigator
Duration: 7/1/2009 - 6/30/2014
 
Title: MD Anderson Cancer Center Support Grant Head and Neck Oncology Program - Project 9
Funding Source: NIH/NCI
Role: Program Member
Principal Investigator: DePinho, Ronald MD
Duration: 7/1/2008 - 6/30/2018

Last updated: 12/5/2014