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Mong-Hong Lee, Ph.D.

Present Title & Affiliation

Dual/Joint/Adjunct Appointment

Professor, Department of Molecular and Cellular Oncology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd.
Unit Number: Unit 108
Houston, TX 77030
Room Number: Y7.6075
Phone: (713) 794-1323
Fax: (713) 794-3270

Education & Training

Degree-Granting Education

1993 University of Pittsburgh, Pittsburgh, PA, PHD, Molecular, Cellular, & Developmental Biology
1984 National Taiwan University, Taipei, Taiwan, BS, Agricultural Chemistry

Postgraduate Training

1993-1997 Postdoctoral Fellowship, Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, NY, Dr. Joan Massague


Academic Appointments

Associate Professor, Department of Molecular and Cellular Oncology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/2004-2010

Other Appointments/Responsibilities

Joint Faculty Member, Texas A&M Health Science Center Greaduate Scho0llo of Biomedical Sciences, Houston, TX, 2010-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Esteva FJ, Moulder SL, Gonzalez-Angulo AM, Ensor J, Murray JL, Green MC, Koenig KB, Lee MH, Hortobagyi GN, Yeung SC. Phase I trial of exemestane in combination with metformin and rosiglitazone in nondiabetic obese postmenopausal women with hormone receptor-positive metastatic breast cancer. Cancer Chemother Pharmacol 71(1):63-72, 1/2013. e-Pub 9/2012. PMCID: PMC3536885.
2. Chen B, Zhao R, Su CH, Linan M, Tseng C, Phan L, Fang L, Yang HY, Yang H, Wang W, Xu X, Jiang N, Cai S, Jin F, Yeung SC, Lee MH. CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6. Cell Cycle 11(24):4633-41, 12/2012. e-Pub 11/2012. PMID: 23187808.
3. Teng CL, Hsieh YC, Phan L, Shin J, Gully C, Velazquez-Torres G, Skerl S, Yeung SC, Hsu SL, Lee MH. FBXW7 is involved in Aurora B degradation. Cell Cycle 11(21):4059-68, 11/2012. e-Pub 10/2012. PMCID: PMC3507501.
4. Xue Y, Chen J, Choi HH, Phan L, Chou PC, Zhao R, Yang H, Santiago J, Liu M, Yeung GE, Yeung SC, Lee MH. HER2-Akt signaling in regulating COP9 signalsome subunit 6 and p53. Cell Cycle 11(22):4181-90, 11/2012. e-Pub 10/2012. PMCID: PMC3524214.
5. Wu CC, Yang TY, Yu CT, Phan L, Ivan C, Sood AK, Hsu SL, Lee MH. p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation. Cell Cycle 11(18):3433-42, 9/2012. e-Pub 8/2012. PMCID: PMC3466554.
6. Tu SM, Som A, Tu B, Logothetis CJ, Lee MH, Yeung SC. Effect of Paget's disease of bone (osteitis deformans) on the progression of prostate cancer bone metastasis. Br J Cancer 107(4):646-51, 8/2012. e-Pub 7/2012. PMCID: PMC3419961.
7. Gully CP, Velazquez-Torres G, Shin JH, Fuentes-Mattei E, Wang E, Carlock C, Chen J, Rothenberg D, Adams HP, Choi HH, Guma S, Phan L, Chou PC, Su CH, Zhang F, Chen JS, Yang TY, Yeung SC, Lee MH. Aurora B kinase Phosphorylates and Instigates Degradation of p53. Proc Natl Acad Sci U S A 109(24):E1513-22, 6/2012. e-Pub 5/2012. PMCID: PMC3386093.
8. Pan J, Chen C, Jin Y, Fuentes-Mattei E, Velazquez-Tores G, Benito JM, Konopleva M, Andreeff M, Lee MH, Yeung SC. Differential impact of structurally different anti-diabetic drugs on proliferation and chemosensitivity of acute lymphoblastic leukemia cells. Cell Cycle 11(12):2314-26, 6/2012. e-Pub 6/2012. PMCID: PMC3383592.
9. Qu C, Liang Z, Huang J, Zhao R, Su C, Wang S, Wang X, Zhang R, Lee MH, Yang H. miR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN. Cell Cycle 11(4). e-Pub 2/2012. PMID: 22306986.
10. Matthias N, Lockworth CR, Zhang F, Lee MH, Yeung SC, Tsai KY, Hamir AN. Multiple cystic sweat gland tumors in transgenic mice. Comp Med 62(1):27-30, 2/2012. PMCID: PMC3276389.
11. Yang HY, Wen YY, Lin YI, Pham L, Su CH, Yang H, Chen J, Lee MH. Roles for negative cell regulator 14-3-3sigma in control of MDM2 activities. Oncogene 26(52):7355-62, 11/2007. e-Pub 6/2007. PMID: 17546054.
12. Yang HY, Yang H, Zhao R, Lee MH. Modified p27 Kip1 is efficient in suppressing HER2-mediated tumorigenicity. J Cell Biochem 98:128-38, 5/2006. PMID: 16365885.

Last updated: 3/10/2014