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Richard A. Amos, M.Sc.

Present Title & Affiliation

Primary Appointment

Senior Medical Physicist, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Associate Faculty, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX

Education & Training

Degree-Granting Education

1994 University of Birmingham, Birmingham, United Kingdom, M.Sc, Applied Radiation Physics
1993 Coventry University, Coventry, United Kingdom, B.Sc, (hons), Applied Physics

Postgraduate Training

1994-1996 Clinical Residency, Medical Physics, Royal Free Hospital, London, England, United Kingdom, John Agnew, PhD

Board Certifications

2008 Institute of Physics and Engineering in Medicine
2004 The Science Council
1998 Institute of Physics

Experience/Service

Academic Appointments

Assistant Professor, Department of Radiation Technology, Loma Linda University, Loma Linda, CA, 11/2004-6/2006
Medical Physicist, Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, CA, 4/2002-7/2005
Medical Physicist, Department of Medical Physics, Kingston Regional Cancer Centre, Kingston, ON, Canada, 6/2000-3/2002
Adjunct Lecturer, Department of Radiation Oncology, Faculty of Medicine, Queen's University, Kingston, Canada, 2000-2002
Radiation Biophysicist, Gray Laboratory, Northwood, United Kingdom, 12/1998-6/2000
Medical Physicist, Department of Radiation Oncology, Kent and Canterbury Hospital, Canterbury, United Kingdom, 2/1996-12/1998

Administrative Appointments/Responsibilities

Member, Department of Oncology Committee, Queen's University, Kingston, ON, Canada, 6/2000-6/2002
Student Representative, Physics Course Consultative Committee, Coventry University, Coventry, United Kingdom, 10/1992-7/1993

Other Appointments/Responsibilities

Co-Chair, Thoracic Proton Therapy Implementation Group, The University of Texas MD Anderson Cancer Center, Houston, TX, 1/2006-5/2006

Honors and Awards

2006 Leadership Award for Special Contributions in the field of Clinical Service, The University of Texas M.D. Anderson Cancer Center
1993-1994 European Social Fund - Graduate Scholarship
1992 Mensa Membership

Professional Memberships

American Association of Physicists in Medicine
Full Member, 2002-present
American College of Medical Physics, College Park, MD
Full Member, 2009-present
Canadian Organization of Medical Physicists, Canada
Full Member, 2000-2004
Institute of Physics, United Kingdom
Full Member, 1993-present
Institute of Physics and Engineering in Medicine, United Kingdom
International Editor for N. America, 2009-present
Institute of Physics and Engineering in Medicine, United Kingdom
Member of Editorial Team, SCOPE Magazine, 2009-present
Full Member, 1995-present
Proton Collaborative Group
Data safety monitoring board member, 2010-present
The British Institute of Radiology, London, United Kingdom
Member, 2008-present

Selected Publications

Peer-Reviewed Original Research Articles
1. Pugh TJ, Amos RA, John-Babtiste S, Choi S, Nguyen QN, Zhu XR, Palmer MB & Lee AK. Multi-field optimization intensity-modulated proton therapy (MFO-IMPT) for prostate cancer: robustness analysis through simulation of rotational and translational alignment errors. Med Dosi. In Press.
2. Giebeler A, Newhauser WD, Amos RA, Mahajan A. Homann K & Howell RM. Standardized treatment planning methodology for passively scattered proton craniospinal irradiation. Radiat Oncol, 2/2013. PMCID: PMC23375151.
3. Boehling NS, Grosshans DR, Bluett JB, Palmer MT, Song X, Amos RA, Sahoo N, Meyer JJ, Mahajan A, Woo SY. Dosimetric comparison of three-dimensional conformal proton radiotherapy, intensity-modulated proton therapy, and intensity-modulated radiotherapy for treatment of pediatric craniopharyngiomas. Int J Radiat Oncol Biol Phys 82(2):643-52, 2/1/2012. e-Pub 1/27/2011. PMID: 21277111.
4. Anand A, Sahoo N, Zhu XR, Sawakuchi GO, Poenisch F, Amos RA, Ciangaru G, Titt U, Suzuki K, Mohan R, Gillin MT. A procedure to determine the planar integral spot dose values of proton pencil beam spots. Med Phys 39(2):891-900, 2/2012. PMCID: PMC3277608.
5. Amos RA, Woodward WA. Field match verification during combination proton, photon and electron therapy for oligometastatic inflammatory breast cancer. Med Dosim 37(4):442-4, 2012. e-Pub 5/19/2012. PMID: 22609618.
6. Wang X, Amos RA, Zhang X, Taddei PJ, Woodward WA, Hoffman KE, Yu TK, Tereffe W, Oh J, Perkins GH, Salehpour M, Zhang SX, Sun TL, Gillin M, Buchholz TA, Strom EA. External-beam accelerated partial breast irradiation using multiple proton beam configurations. Int J Radiat Oncol Biol Phys 80(5):1464-72, 8/1/2011. e-Pub 8/12/2010. PMCID: PMC3249354.
7. Meyer JJ, Bluett JB, Amos RA, Levy LB, Choi S, Nguyen Q, Gillin MT, Lee AK. Scanning proton beam therapy for prostate cancer: treatment planning techniques and analysis of consequences of rotational and translational alignment errors. Int J Radiat Oncol Biol Phys 78(2):428-34, January 25, 2010, 10/2010. PMID: 20100641.
8. Bouchard M, Amos RA, Briere TM, Beddar S, Crane CH.. Dose escalation with proton or photon radiation treatment for pancreatic cancer. Radiother Oncol 92(2):238-43, 2009. PMID: 19454367.
9. Sejpal SV, Amos RA, Bluett JB, Levy LB, Kudchadker RJ, Johnson JL, Choi S, Lee AK.. Dosimetric changes resulting from patient rotational setup errors in proton therapy prostate plans. Int J Radiat Oncol Biol Phys 75(1):40-8, September 1, 2009, 2009. PMID: 19058919.
10. Kudchadker RJ, Lee AK, Yu ZH, Johnson JL, Zhang L, Zhang Y, Amos RA, Nakanishi H, Ochiai A, Dong L. The effectiveness of using fewer implanted fiducial markers for prostate target alignment. Int J Radiat Oncol Biol Phys 74(4):1283-9, July 15, 2009, 2009. PMID: 19427750.
11. Sahoo N, Zhu XR, Arjomandy B, Ciangaru G, Lii M, Amos RA, Wu R, Gillin MT.. A procedure for calculation of monitor units for passively scattered proton radiotherapy beams. Med Phys 35(11):5088-97, 2008. PMID: 19070243.

Invited Articles
1. Amos R, Zhu XR, Balter PA, Zhang X, Dong L, Chang JY, Riley BA, Arjomandy B, Sahoo N, Gillin MT, Cox JD. Treatment planning for proton irradiation of thoracic tumors. Proceedings of the NIRS-MD Anderson symposium on clinical issues for particle therapy. NIRS M.D. Anderson Symposium, 3/2008.
Other Articles
1. Amos RA. Proton therapy moves into US mainstream practice. SCOPE Magazine 18(3):42, 2009.

Abstracts
1. Meyer JJ, Bluett JB, Amos RA, Levy LB, Choi S, Nguyen Q, Zhu XR, Gillin MT, Lee AK. Spot scanning proton radiation therapy for prostate cancer: treatment technique and dosimetric consequences of rotational and translational setup errors. Genitourinary Cancers Symposium, 2009.
2. Wang X, Woodward WA, Zhang X, Taddei PJ, Amos RA, Salehpour M, Zhang SX, Buchholz TA, Strom EA. Non-target tissue sparing with passive scattered proton partial-breast irradiation planning. Int J Radiat Oncol Biol Phys 75(3):S200, 2009.
3. Komaki R, Sejpal SV, Wei X, Allen PK, Amos RA, Mohan R, Chang JY, Liao Z, Dong L, Cox JD. Significant reduction of bone marrow toxicity (BMT) for patients with locally advanced (LA) NSCLC treated with concurrent chemotherapy (CT) and proton beam therapy (PBT) compared to intensity modulated radiation therapy (IMRT). Radiother Oncol 90(S3):S61, 2009.
4. Matney J, Vedam SS, Dong L, Amos RA, Zhu XR, Balter P, Mohan R. Is average CT a good estimate of mid-ventilation position of surrounding normal structures for proton therapy treatment planning of lung tumors?. Med Phys 36(6):2710, 2009.
5. Meyer JJ, Bluett JB, Li Y, Zhang X, Chi L, Nguyen N, Zhu XR, Amos RA, Lee AK, Woo S. Incorporation of range uncertainty into dosimetric analysis of proton radiotherapy plans: generating "worse case scenarios" for doses to critical structures. Oncol Biol Phys 75(3):S700, 2009.
6. Sejpal SV, Amos R, Bluett JB, Levy LB, Kudchadker RJ, Johnson, JL, Choi S, Lee AK. Dose deviations in proton therapy prostate plans for patients treated with alternating daily fields in the context of rotational setup errors. ACRO, 2/2008.
7. Amos R, Zhu XR, Balter PA, Zhang X, Dong L, Chang JY, Riley BA, Arjomandy B, Sahoo N, Gillin MT, Cox JD. Treatment planning for proton irradiation of thoracic tumors. Proceedings of the NIRS-MD Anderson symposium on clinical issues for particle therapy. NIRS-MD Anderson symposium on clinical issues for particle therapy, 3/2008.
8. Sejpal SV, Komaki R, Wei X, Amos RA, Mohan R, Allen P, Liu H, Liao Z, Chang JY, Cox JD. Does proton beam radiotherapy (PBT) reduce treatment related pneumonitis (TRP) compared to intensity modulated radiation therapy (IMRT) in patients with locally advanced non-small cell lung cancer (NSCLC) treated with concurrent chemotherapy?. PTCOG Co-Operative Group 47th Int Conference, 5/2008.
9. Sejpal SV, Komaki R, Wei X, Amos RA, Allen P, Liu H, Liao Z, Change JY, Cox JD. Preliminary evaluation of treatment-related pneumonitis (TRP) by proton beam radiotherapy (PBT) compared to intensity-modulated radiation therapy (IMRT) in patients with locally advanced non-small-cell lung cancer treated with concurrent chemotherapy. American Radium Society 90th Annual Meeting, 5/2008.
10. Komaki R, Sejpal SV, Wei X, Allen P, Chang JY, Liao Z, Mohan R, Dong L, Amos RA, Cox JD. Reduction of bone marrow suppression for patients with stage III NSCLC treated by proton and chemotherapy compared with IMRT and chemotherapy. PTCOG Co-Operative Group 47th Int Conference, 5/2008.
11. Sahoo N, Zhu XR, Arjomandy B, Amos RA, Johnson JL, Lii M, Wu R, Ciangaru G, Ding X, Zhu M, Newhauser WD, Titt U, Gillin MT. Summary of our experience of patient treatment related physics quality assurance activities at the Proton Therapy Center-Houston. PTCOG Co-Operative Group 47th Int Conference, 5/2008.
12. Amos RA, Bouchard M, Briere TM, Crane C, Beddar S, Gillin MT. Proton therapy for pancreatic cancer: A treatment planning study. Institute of Physics and Engineering in Medicine Biennial Radiotherapy Meeting, 9/2008.
13. Bouchard M, Briere TM, Amos RA, Beddar S, Crane C. Dose escalation with proton or photon radiation treatment for pancreatic cancer. Int J Radiat Oncol Biol Phys Vol 72(1):S540, 2008.
14. Wu R, Amos RA, Sahoo N, Kornguth D, Bluett JB, Gillin MT, Zhu XR. Effect of CT truncation artifacts to proton dose calculation. Med Phys Vol 35:2697, 2008.
15. Sejpal SV, Amos RA, Bluett JB, Levy LB, Kudchadker RJ, Johnson JL, Choi S, Lee AK. Evaluation of dose changes to target and critical structures from rotational setup errors (RSE) in prostate cancer patients treated with proton therapy. Int J Radiat Oncol Biol Phys Vol 72(1):S321, 2008.
16. Sejpal SV, Amos RA, Bluett JB, Levy LB, Kudchadker RJ, Johnson JL, Choi S, Lee AK. Evaluation of dose changes to target and critical structures from rotational setup errors (RSE) in prostate cancer patients treated with proton therapy. Int J Radiat Oncol Biol Phys 72(1):S321, 2008.
17. Bouchard M, Briere TM, Amos RA, Crane C, Beddar S. Impacts of dose distribution variations in proton therapy according to gastro-intestinal tract air filling and breathing. Med Phys Vol 35:2968, 2008.
18. Komaki R, Sejpal SV, Wei X, Allen PK, Amos RA, Mohan R, Chang JY, Liao Z, Dong L, Cox JD. Significant reduction of bone marrow toxicity (BMT) for patients with locally advanced (LA) NSCLC treated with concurrent chemotherapy (CT) and proton beam therapy (PBT) compared to intensity modulated radiation therapy (IMRT). J Tho Oncol 3(11(S4)):S303, 2008.
19. Liengsawangwong P, Ding X, Arjomandy B, Lii J, Sahoo N, Amos R, Gillin M, Zhu X. 2-D Diode Array for Measurements of Passive Scattering Proton Beams with Compensators. Particle Therapy Co-Operative Group 46th International Conference, 5/2007.
20. Bues M, Amos R, Riley B, Schaffner B, Lee A. Treating Prostate Cancer with Passively Scattered and Scanned Proton Beams: A Comparative Planning Study. Particle Therapy Co-Operative Group 46th International Conference, 5/2007.
21. Amos R, Bucci M, McAleer M, Komaki R, Liao Z, Chang J, Arjomandy B, Zhu X, Gillin M, Cox J. Variation in Dose Distribution with Tumor Shrinkage for Proton Therapy of Lung Cancer. Particle Therapy Co-Operative Group 46th International Conference, 5/2007.
22. Sahoo N, Zhu X, Zhu M, Amos R, Kudchadker R, Johnson J, Arjomandy B, Lii M, Wu R, Gillin M. Analysis of the Accuracy of a Monitor Unit Calculation Procedure for Passively Scattered Proton Therapy Beams. Proceedings of the 49th Annual Meeting of the American Society for Therapeutic Radiology and Oncology 69(3):S689-S690, 2007.
23. Liengsawangwong P, Ding X, Arjomandy B, Lii J, Sahoo N, Amos R, Gillin M, Zhu X. Dosimetric Characterization of a 2D Diode Array Detector in Passive Scattering Proton Beams 34:2440, 2007.
24. Melancon A, Dong L, Kudchadker R, Amos R, Johnson J, Zhang Y, Yu Z, Zhang L, Lee A. Evaluation and Comparison of Inter-Fractional Femoral Head Variations for Two Pelvic Immobilization Devices. Devices 34:2384, 2007.
25. Wu R, Zhang X, Amos R, Prado K, Lii M, Sahoo N, Gillin M, Zhu X. Evaluation of Titanium Metal Imaging Artifacts on Proton Dose Calculation 34:2452, 2007.
26. Lee A, Kudchadker R, Amos R, Johnson J, Choi S, Kuban D, Cox J, Mohan R, Gillin M, Dong L. Proton Therapy vs. IMRT for Prostate Cancer: A Dosimetric Comparison. Proceedings of the 49th Annual Meeting of the American Society for Therapeutic Radiology and Oncology 69(3):S342, 2007.
27. Sahoo N, Zhu X, Lii M, Amos R, Arjomandy B, Wu R, Gillin M, Zhu X. Study of Dose Distribution in Passively Scattered Proton Beams for Small Field Sizes 34:2491, 2007.
28. Yu Z, Kudchadker R, Zhang L, Johnson J, Zhang Y, Amos R, Dong L, Lee A. The Effectiveness of Using Fewer Implanted Fiducial Markers for Prostate Target Alignment. Proceedings of the 49th Annual Meeting of the American Society for Therapeutic Radiology and Oncology 69(3):S629-S630, 2007.
29. Sahoo N, Zhu X, Wu R, Titt U, Amos R, Newhauser W, Zullo J, Gillin M. Beam Characteristics of the Passively Scattered Proton Beam at PTC-H. Particle Therapy Co-Operative Group 45th International Conference, 10/2006.
30. Sahoo N, Zhu X, MingFwu L, Zhang X, Amos R, Wu R, Zullo J, Barfield M, Arjomandy B, Titt U, Newhauser W, Mohan R, Gillian M. Clinical Commissioning of the Eclipse Treatment Planning System for Protons. Particle Therapy Co-Operative Group 45th International Conference, 10/2006.
31. Zullo J, Gillin M, Sahoo N, Zhu X, Amos R. Periodic Quality Assurance Testing Recommendations for the Proton Therapy Center. Particle Therapy Co-Operative Group 45th International Conference, 10/2006.
32. Amos R, Johnson J, Kudchadker R, Dong L. Lee A. Target Dose Coverage in the Presence of Alignment Rotation for Proton Therapy of Prostate Cancer. Particle Therapy Co-Operative Group 45th International Conference, 10/2006.
33. Kudchadker R, Lee A, Johnson J, Amos R, Zhang L. Dong L. Use of a Single Implanted Fiducial Marker for Prostate Target Alignment. Particle Therapy Co-Operative Group 45th International Conference, 10/2006.
34. Zullo J, Amos R, Bucci M, Billin M. Verification of Eclipse Lung Dose Calculations for Proton Beams. Particle Therapy Co-Operative Group 45th International Conference, 10/2006.
35. Ly A, Benson B, Moyers M, Amos R. Commissioning of the EYEPLAN V3.01 at LLUMC 33:2029, 2006.
36. Johnson J, Lee A, Kudchadker R, Amos R, Frank S, Cheung R, Kuban D, Dong L. Comparison of Prostate Implanted Fiducials with CT and Ultrasound for Prostate Target Localization: Initial Results 33:2029, 2006.
37. Zhang X, Chang J, Liao Z, Komaki R, Cox J, Amos R, Arjomandy B, Kang Y, Wang X, Liu H, Dong L, Mohan R. Thoracic Proton Treatment Planning Strategies Based on the 4D-CT Information 33:2269, 2006.
38. Anand A, Sahoo N, Zhu XR, Sawakuchi GO, Poenisch, F, Amos RA, Suzuki K, Mohan R & Gillin MT. A technique to determine the integral depth dose of proton pencil beam spots. Med Phys 37(6):3363, 2010.
39. Amos RA & Woodward WA. Field matching for combined proton, photon and electron post-mastectomy radiation therapy (PMRT) for breast cancer. 2010.
40. Komaki R, Sejpal SV, Wei X, Allen PK, Amos RA, Mohan R, Chang JY, Liao Z, Dong L & Cox JD. Reduction of normal tissue (NT) toxicity in patients with locally advanced (LA) NSCLC treated with concurrent chemotherapy (ChT) and proton beam therapy (PBT) compared to intrensity modulated radiation therapy (IMRT). 2010.
41. Boehling NS, Grosshans DR, Bluett JB, Palmer MT, Song X, Amos RA, Sahoo N, Meyer JJ, Mahajan A & Woo SY. Dosimetric comparison of protons vs. intensity modulated radiation therapy (IMRT) for treatment of craniopharyngiomas in children. 2010.
42. Amos RA, Strom EA, Hoffman KE, Wang X, Salehpour M, Buchholz TA, Woodward WA. Supine set-up and adaptive planning for accelerated partial breast irradiation (APBI) using protons. 50th International Conference of the Particle Therapy Co-Operative Group, Philadelphia, PA, USA 6.1.6 (2011), 2011.
43. Anand A, Sahoo N, Zhu XR, Titt U, Sawakuchi G, Li Y, Poenisch F, Amos RA, Suzuki K, Ciangaru G, Mohan R, Gillin MT. Scanned proton pencil beam's lateral profile library to describe the spot dose characteristics. 2011 Joint Meeting of the American Association of Physicists in Medicine and the Canadian Organization of Medical Physicists, Vancouver, BC, Canada 38(6):3855, 2011.
44. Wang X, Zhang X, Amos RA, Salehpour M, Zhang SX, Sun TL, Strom EA, Buchholz TA, Hoffman KE, Woodward WA. External beam accelerated partial breast irradiation using intensity modulated proton therapy (IMPT). 2011 Joint Meeting of the American Association of Physicists in Medicine and the Canadian Organization of Medical Physicists, Vancouver, BC, Canada 38(6):3669, 2011.
45. Amos RA, Wang X, Salehpour M, Strom EA, Hoffman Ke, Buchholz TA, McRae SE, Lee AK, Woodward WA. Eliminating dose to organs at risk during proton accelerated partial breast irradiation (APBI) through temporary, minimally invasive tissue displacement: Proof of principle in silico. Int J Radiat Oncol Biol Phys 53rd Annual Meeting of the American Society for Radiation Oncology, Miami, Beach, FL 81(2):S887, 2011.
46. Amos RA. Exploiting the proton advantage with a little intervention. 32nd Annual Conference of the Association of Medical Physicists of India, Vellore, India:14, 2011.
47. Pugh TJ, Amos RA, John-Baptiste SJ, Choi S, Nguyen Q, Zhu XR, Palmer MB and Lee AK. Intensity-modulated proton therapy with multi-field optimization: robustness analysis through simulation of rotational and translational alignment errors in the treatment of prostate cancer. 94th Annual Meeting of the American Radium Society, Las Vegas, NV 26(4):62-3, 2012.
48. Amos RA. Rectal dose reduction through tissue displacement during intensity-modulated proton therapy (IMPT) for prostate cancer. 2012 Medical Physics and Engineering Conference and Biennial Radiotherapy Conference of the Institute of Physics and Engineering in Medicine, Abstract Book ISBN 978-1-903613-51-1:128-9, 2012.
49. Sahoo N, Dhanesar SK, Song X, Poenisch F, Lii M, Li H, Amos RA, Wu R, Gillin MT, Zhu XR. Determination of spread out Bragg peak factors and range shifter factors from measured depth dose curves for passively scattered proton beams. Int J Radiat Oncol Biol Phys 84(3):S849, 2012.

Last updated: 3/5/2013