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Rodney S. Nairn, Ph.D.

Present Title & Affiliation

Primary Appointment

Professor, Department of Carcinogenesis, Science Park - Research Division, U.T. M.D. Anderson Cancer Center, Smithville, TX

Education & Training

Degree-Granting Education

1977 Texas A&M University, College Station, TX, PHD, Biochemistry
1972 Texas A&M University, College Station, TX, BS, Biochemistry
1972 Texas A&M University, College Station, TX, BS, Microbiology

Postgraduate Training

6/1979-9/1980 Research Fellowship, Radiation Genetics, University of Texas Cancer Center, Science Park - Research Division, Smithville, TX, R.M. Humphrey
9/1975-8/1977 Research Fellowship, Molecular Genetics, Texas A&M University, College Station, G.A. O'Donovan
9/1972-8/1974 Research Internship, Biochemical Genetics, Texas A&M University, College Station, B.F. Watson

Experience/Service

Academic Appointments

Visiting Professor and Adjunct Member of the Graduate Faculty in Chemistry and Biochemistry, Texas State University, San Marcos, TX, 1/1999-8/2003
Member of Graduate Faculty, Graduate School of Biomedical Sciences, University of Texas at Houston, Smithville, TX, 1/1983-present

Selected Publications

Peer-Reviewed Original Research Articles
1. Talbert LL, Coletta LD, Lowery MG, Bolt A, Trono D, Adair GM, Nairn RS. Characterization of CHO XPF mutant UV41: Influence of XPF heterozygosity on double-strand break-induced intrachromosomal recombination. DNA Repair 7(8):1319-29, 8/2008. PMCID: PMC2574431.
2. Butler AP, Trono D, Beard R, Fraijo R, Nairn RS. Melanoma susceptibility and cell cycle genes in Xiphophorus hybrids. Mol Carcinog 46(8):685-91, 8/2007. PMID: 17477382.
3. Butler AP, Trono D, Coletta LD, Beard R, Fraijo R, Kazianis S, Nairn RS. Regulation of CDKN2A/B and Retinoblastoma genes in Xiphophorus melanoma. Comp Biochem Physiol C Toxicol Pharmacol 145(1):145-55, 2/2007. PMID: 17011832.
4. Mitchell DL, Nairn RS. Photocarcinogenesis in Xiphophorus hybrid models. Zebrafish 3(3):311-23, 2006. PMID: 18377212.
5. Adair GM, Rolig RL, Moore-Faver D, Zabelshansky M, Wilson JH, Nairn RS. Role of ERCC1 in removal of long non-homologous tails during targeted homologous recombination. Embo J 19(20):5552-61, 10/2000. PMCID: PMC313999.
6. Kazianis S, Coletta LD, Morizot DC, Johnston DA, Osterndorff EA, Nairn RS. Overexpression of a fish CDKN2 gene in a hereditary melanoma model. Carcinogenesis 21(4):599-605, 4/2000. PMID: 10753192.
7. Sargent RG, Rolig RL, Kilburn AE, Adair GM, Wilson JH, Nairn RS. Recombination-dependent deletion formation in mammalian cells deficient in the nucleotide excision repair gene ERCC1. Proc Natl Acad Sci U S A 94(24):13122-7, 11/1997. PMCID: PMC24273.
8. Rolig RL, Layher SK, Santi B, Adair GM, Gu F, Rainbow AJ, Nairn RS. Survival, mutagenesis, and host cell reactivation in a Chinese hamster ovary cell ERCC1 knock-out mutant. Mutagenesis 12(4):277-83, 7/1997. PMID: 9237774.
9. Nairn RS, Kazianis S, McEntire BB, Della Coletta L, Walter RB, Morizot DC. A CDKN2-like polymorphism in Xiphophorus LG V is associated with UV-B-induced melanoma formation in platyfish-swordtail hybrids. Proc Natl Acad Sci U S A 93(23):13042-7, 11/1996. PMCID: PMC24043.
10. Adair GM, Nairn RS, Wilson JH, Seidman MM, Brotherman KA, MacKinnon C, Scheerer JB. Targeted homologous recombination at the endogenous adenine phosphoribosyltransferase locus in Chinese hamster cells. Proc Natl Acad Sci U S A 86(12):4574-8, 6/1989. PMCID: PMC287313.
11. Adair GM, Stallings RL, Nairn RS, Siciliano MJ. High-frequency structural gene deletion as the basis for functional hemizygosity of the adenine phosphoribosyltransferase locus in Chinese hamster ovary cells. Proc Natl Acad Sci U S A 80(19):5961-4, 10/1983. PMCID: PMC390197.

Invited Articles
1. Mitchell DL, Nairn RS. The biology of the (6-4) photoproduct. Photochem Photobiol 49(6):805-19, 6/1989. PMID: 2672059.

Last updated: 7/31/2009