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S. Egbert Pravinkumar, MD, FRCP, EDIC

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Critical Care, Division of Anesthesiology and Critical Care, The University of Texas MD Anderson Cancer Center, Houston
Associate Medical Director, Department of Critical Care, Division of Anesthesiology and Critical Care, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Associate Professor, Clinical Ethics, The Section of Integrated Ethics in Cancer Care, The University of Texas MD Anderson Cancer Center, Houston, TX
Educator/Adjunct Faculty, Department of Anesthesiology and Perioperative Medicine, Division of Anesthesiology and Critical Care, Baylor College of Medicine Resident Training Program, Houston, TX
Educator/Adjunct Faculty, Department of Anesthesiology and Perioperative Medicine, Division of Anesthesiology and Critical Care, University of Texas Health Science Center Resident Training Program, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Boulevard
Unit Number: 112
Houston, TX 77030-4009
Room Number: B7:4306, Dept. Critical Care, Division of Anesthesiology and Critical Care
Phone: 713-792-5040
Fax: 713-745-1869
Email: epravink@mdanderson.org

Education & Training

Degree-Granting Education

2004 European Society of Intensive Care Medicine, European Board of Intensive Care Medicine, Brussels, Belgium, EDIC, Critical Care Medicine
2004 Royal College of Physicians of Ireland, Dublin, Ireland, FRCP, Fellow of Royal College of Physicians, Pulmonary/ Internal Medicine
2001 University of Leeds, Leeds, West Yorkshire, United Kingdom, PG Cert. Health Res, Healthcare Research
1996 Royal College of Physicians of Ireland, Dublin, Ireland, MRCP, Member of Royal College of Physicians, Pulmonary Medicine/ Internal Medicine
1991 Stanley Medical College and University Hospital, University of Madras, Madras, India, MD, Doctor of Medicine

Board Certifications

7/2004 Critical Care Medicine, European Board of Intensive Care Medicine, European Society of Intensive Care Medicine, Brussels, Belgium
12/2002 Intercollegiate Board for Training in Intensive Care Medicine, London, United kingdom
1/2002 Pulmonary Medicine, Postgraduate Medical Education and Training Board, Specialist Training Authority of Medical Royal Colleges, London, United Kingdom
1/2002 Internal Medicine, Postgraduate Medical Education and Training Board, Specialist Training Authority of Medical Royal Colleges, London, United Kingdom
6/1996 Internal Medicine, Royal College of Physicians, Dublin, Ireland

Experience/Service

Academic Appointments

Ethicist, Clinical Ethics Service and Section of Cancer Bioethics, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 7/2004-8/2008
Faculty and Lecturer, College of Life Sciences and Medicine, Institute of Medical Sciences and Aberdeen Royal Infirmary, University of Aberdeen, Scotland, Aberdeen, Scotland, United Kingdom, 11/2001-4/2004

Selected Publications

Peer-Reviewed Original Research Articles
1. Bruno JJ, Hernandez M, Ghosh S, Pravinkumar SE. Critical Illness-Related Corticosteroid Insufficiency in Cancer Patients. Support Care Cancer. e-Pub 5/2011. PMID: 21604086.
2. Ramos ER, Reitzel R, Jiang Y, Hachem RY, Chaftari AM, Chemaly RF, Hackett B, Pravinkumar SE, Nates J, Tarrand JJ, Raad II. Clinical Effectiveness and Risk of Emerging Resistance Associated with Prolonged Use of Antibiotic-Impregnated Catheters: More than 0.5 Million Catheter Days and 7 Years of Clinical Experience (Featured Article). Crit Care Med 39(2):245-251, 2/2011. PMCID: PMC21057308.
3. Chaftari AM, Kassis C, El Issa H, Al Wohoush I, Jiang Y, Rangaraj G, Caillouet B, Pravinkumar SE, Hachem RY, Raad II. Novel approach using antimicrobial catheters to improve the management of central line-associated bloodstream infections in cancer patients. Cancer, http://onlinelibrary.wiley.com/doi/10.1002/cncr.25807/abstract. e-Pub 12/2010. PMID: 21157952.
4. Pravinkumar SE. Noninvasive Positive Pressure Ventilation in Malignancy. HEMJ 1(5), http://www.medical-journal.co.uk/search.asp, 2/2010.
5. Bilen MA, Waguespack SG, Tannir NM, Pravinkumar SE, Tamboli P, Tu SM. Multisystem Crisis in a Patient with Presumptive Renal Cell Carcinoma. Clin Genitourin Cancer 6(2):128-30, 9/2008. PMCID: PMC18824438.
6. Pravinkumar E, Webster NR. HIT/HITT and Alternate Anticoagulation: Current Concepts. Anesthesia File- CME 20(9):155.0302, 9/2003.
7. Pravinkumar E, Webster NR. HIT/HITT and Alternate Anticoagulation: Current Concepts. BJA International Journal of Anaesthesia, South African Excerpts Edition 3(4):255-264, 8/2003.
8. Pravinkumar E. Peer review and appeal: flawed but trusted? Lancet 362(9385):747, 8/2003. PMCID: PMC12957106.
9. Pravinkumar E, Webster NR. HIT/HITT and Alternative Anticoagulation: Current Concepts. Br J Anaesth 90(5):676-85, 5/2003. PMCID: PMC12697598.
10. Bruno JJ, Dee BM, Anderegg BA, Hernandez M, PravinkumarSE. US Practitioner Opinions and Prescribing Practices Regarding Corticosteroid Therapy for Severe. J Crit Care. Submitted.

Editorials
1. Pravinkumar SE. A Face that Matters in Distress: Interface Selection for Acute Noninvasive Ventilation. Crit Care Med 37(1):344-346, 1/2009. PMCID: PMC19112296.

Abstracts
1. Warren ML, Pravinkumar SE, Frankel S, Ryan S, Nguyen V, Garcia R, Thomas M, Withers L, Nguyen Q. The Implementation and Evaluation of an Early Mobilization Program for Critically Ill Adult Oncology Patients. Crit Care Med (#657). In Press.
2. Nates JL, Rathi N, Haque S, Gaeta S, Pravinkumar SE, Botz G, Chen K, Crommett J, Calabrese D, De Villalobos D, Malik I, Price K. ICU Triage Improves Patient Flow and Resource Utilization. CHEST 140(4):357A, http://chestjournal.chestpubs.org/search?fulltext=Pravinkumar&submit=yes, 10/2011.
3. Pravinkumar SE, Nigam R, Hwu P, Davies MA, Price K. Intensive Care Resource Utilization for High Dose Interleukin-2 Therapy: A 3-Year Experience from a Large Oncologic ICU. Can Respir J 18(Suppl A):19A, 5/2011.
4. Nates JL, Perego C, Finch C, Chemaly R, Jordan V, Terrell J, Pravinkumar SE, Raad I, Price K. Ventilator-Associated Pneumonia (VAP) Can Be Eradicated. Successful VAP prevention Program in a Comprehensive Cancer Center Surgical ICU. Crit Care Med 38(12):S411 (#S411), 12/2010.
5. Dee BM, Lal L, Pravinkumar SE.. Effect of Nebulized Dornase Alfa on Pulmonary Gas Exchange in Critically Ill Stem Cell Transplant Recipients. Biol Blood Marrow Tr 16(2):S317 (#436), 2/2010.
6. Bruno JJ, Hernandez M, Pravinkumar SE. Current Opinions and Prescribing Practices for Corticosteroid Therapy in Severe Sepsis and Septic Shock: Survey of US Practitioners. Crit Care Med 37(12) (#497), 12/2009.
7. Dee BM, Lal L, Pravinkumar SE. Effect of Inhaled Dornase Alfa on Gas Exchange in Critically Ill Adult Cancer Patients. Crit Care Med 37(12):A195 (#407), 12/2009.
8. Mulanovich VE, Perego CL, Borchardt R, Pravinkumar SE, Chemaly RF, Rolston KVI, Adachi JA. Antimicrobial Stewardship Project in the Intensive Care Unit: Impact on Quality of Care and Patient Safety. CS&E: Building the Bridge at the Quality Chasm, 10/2009.
9. Sachdeva KS, Lal, AP, Salahudeen A, Pravinkumar SE, Davis M. Chronic Kidney Disease induced by IL-2 as a chemotherapeutic agent. JASN - Renal Week Abstracts 2009 (#SA-PO2248), http://asn-online.org/education_and_meetings/renal_week/archives/, 10/2009.
10. Pravinkumar SE, Warren ML, Bruno JJ, Nwankwo C, Finch CG, Price KJ. Implementation of the Institute for Healthcare Improvement Global Trigger Tool in an Oncological ICU: Pilot Data. CHEST 136(4):27S-b (#221), 10/2009.
11. Ghosh S, Finch CG, Champlin R E, Pravinkumar SE. Comparison and Cost Effectiveness of Bronchoscopic and Non-Bronchoscopic Bronchoalveolar Lavage in Hematological Malignancies and Stem Cell Recipients. Biol Blood Marrow Tr 15(2):91-92 (#252), 2/2009.
12. Ramos ER, Jiang Y, Hachem R, Reitzel R, Pravinkumar E, Nates J, Tarrand J, Raad I. The Risk of Emerging Resistance Associated with Prolonged Use of Antibiotic Coated Catheters: A Seven Year Experience and >0.5 Million Catheter Days (2009 Sepsis Specialty Award and Educational Scholarship). Critical Care Medicine 36(12 (Suppl)):A15 (#52), 12/2008. PMCID: PMC19112296.
13. Ghosh S, Finch C, Champlin RE, Kebriaei P, Giralt SA, Pravinkumar SE. Usefulness of Bronchoscopic Lavage in Intensive Care Unit for Critically Ill Stem Cell Recipients with Pulmonary Infiltrates. Biol Blood Marrow Tr 14(2):98 (#266), 2/2008.
14. Bruno JJ, Hernandez M, Chen K, Pravinkumar SE. Influence of Corticosteroids on Cosyntrophin Stimulation Test in Oncology Patients with Severe Sepsis or Septic Shock. Crit Care Med 35(12):A274 (#984), 12/2007.
15. Bruno JJ, Hernandez M, Ghosh S, Pravinkumar SE. Serum Cortisol and Response to High-dose Cosyntrophin Stimulation in Oncology Patients with Severe Sepsis or Septic Shock. Crit Care Med 35(12):A257 (#925), 12/2007.
16. Finch C, Ghosh S, Price KJ, Pravinkumar SE. Post-operative Mechanical Ventilation in Oncological Surgical Intensive Care Unit: Review of Institute of Health Improvements Adverse Event Criteria. Respir Care, 11/2007.
17. Pravinkumar SE, Ghosh S, Price KJ, Finch C. Unplanned Extubations and Outcome in Oncological Intensive Care Unit: 1-Year Experience. Respirology 12(4):A216 (#P-2-086), 11/2007.
18. Ghosh S, Finch C, Price KJ, Pravinkumar SE. Platelet Levels and Safety of Bronchoalveolar Lavage in Critically Ill Cancer Patients. CHEST 132(4):568S (#341), 10/2007.
19. Nates JL, Pravinkumar SE, Price KJ, Finch C, Lee L, Frederick F, Berkheiser M, Baldwin L. Environmental Sampling During High Frequency Ventilation. Crit Care Med 34(12):A88 (#322), 12/2006.
20. Nates JL, Wakefield C, Pravinkumar SE, Price KJ, Perego C, Hackett B, Chemaly R, Raad I, Finch C. Ventilator Associated Pneumonia Rates in Surgical ICU: Surveillance and Interventions in a Comprehensive Cancer Center (2007 Respiratory Specialty Award)). Crit Care Med 34(12):A94 (#347), 12/2006.
21. Pravinkumar SE, Finch C, Binns N, Kannaeth T, Denning I, Nates JL, Price KJ. Bronchoscopic and Nonbronchoscopic Lavage in Critically Ill Cancer Patients with Lung Infiltrates: Diagnostic Yield and Cost-effectiveness. Respir Care 51(11):1281 (#OF-06-136), 11/2006.
22. Bolden M, Finch C, Pravinkumar SE, Mejia D, Nates JL, Price KJ. Role of Respiratory Therapist in the ICU Outreach: Impact of Respiratory Therapist Transitional Service in a Major Cancer Center. Respir Care 51(11):1281 (#OF-06-134), 11/2006.
23. Pravinkumar SE, Finch C, Price KJ, Nates JL. Respiratory Therapist Led Early VAP Surveillance: A Proactive Strategy in an Oncological ICU. Respir Care 51(11):1281 (#OF-06-133), 9/2006.
24. Finch C, Pravinkumar SE, Nates JL, Geevarghese G, Perkins R, Han C, Price KJ. Safety of Non-Bronchoscopic BAL Performed by Respiratory Therapist: Experience from Large Oncological ICU. Respir Care 51(11):1281 (#0F-06-135), 9/2006.
25. Pravinkumar E, Watt A, Galley H, Cuthbertson B, Webster N. Effects of Recombinant Surfactant Protein-C and Elastase Inhibitor on Neutrophil Apoptosis. Crit Care 8(Suppl.1):S54 (#P108), ccforum.com/content/8/S1/P108, 3/2004.
26. Hill KM, Muers MF, Pravinkumar E, Thorpe JA, MacDonald W. A Comparison of Shuttle Walking Test (SWT) and Maximal Oxygen Consumption (V02 Peak) Measured on a Treadmill as Predictors of Outcome Following Lung Resection. 10th European Respiratory Society Annual Congress, 8/2000.
27. Harkins K, Pravinkumar E, Wanklyn P. Cough Reflex and Pneumonia in Acute Stroke (2000 Respiratory Specialty Award). British Association of Stroke Physicians Annual Congress, 2000.
28. Hill KM, Pravinkumar E, Macdonald W, Muers MF. Can the Distance Walked During the Shuttle Walking Test Predict O2 Uptake?. Thorax 54(Suppl.3):A78 (#P239), 12/1999.
29. Pravinkumar SE, Warren ML, Frankel S, Ryan S, Nguyen V, Garcia R, Thomas M, Withers L, Nguyen Q. Sustaining an Early Mobilization Program in an Oncological ICU: Effect of a Simplified 3-Level Versus a Standard 5-Level Mobilization Program. Crit Care Med. Submitted.

Book Chapters
1. Shannon V.R, Eapen G.A, Jimenez. C.A, Morice R.C, Travis E.L, Bashoura. L, Safdar. A, Evans S.E, Adachi. R, Faiz S.A, Balachandran D.D, Nates J.L, Pravinkumar S.E, Dickey B.F.. Complications of Cancer and their Treatment: Respiratory Complications. In: Holland-Frei Cancer Medicine e.8, 8. Ed(s) Waun Ki Hong, Robert C. Bast, William N. Hait, Donald W. Kufe, Raphael E. Pollock, Ralph R. Weichselbaum, James F. Holland, Emil Frei III. BC Decker: USA, 1849-1879, www.cancermedicine8.com, e-Book 2010. PMID: 9781607950141.
2. Pravinkumar S.E. Noninvasive Positive Pressure Ventilation in Acute Hypoxemic Respiratory Failure and in Cancer Patients. In: Noninvasive Mechanical Ventilation - Theory, Equipment, and Clinical Applications, 1. Ed(s) Antonio M. Esquinas. Springer-Verlag: Berlin Heidelberg, Germany, 249-256, 2010. PMID: 978-3-642-11364-2.
3. Pravinkumar S.E, Puana R, Nates J.L.. Ventilación de Positiva Presión No Invasiva en Fallo Respiratorio Agudo en Pacientes con Cáncer. In: Ventilación Mecánica No Invasiva En Inmunocomprometidos- Hematologia Oncologia Transplantados, 1. Ed(s) A.M. Esquinas Rodriguez. Axon, Espanol: Spain, 369-382, 2009. PMID: 9788461272129.
4. Puana R, Pravinkumar S.E, Nates J.L.. Ventilación Mecánica Invasiva en Pacientes con Cáncer con Fallo Respiratorio Agudo. In: Ventilación Mecánica No Invasiva En Inmunocomprometidos- Hematologia Oncologia Transplantados, 1. Ed(s) A.M. Esquinas Rodriguez. Axon, Espanol: Spain, 359-368, 2009. PMID: 9788461272129.
5. Shannon V.R, Eapen G.A, Jimenez. C.A, Morice R.C, Travis E.L, Bashoura. L, Safdar. A, Adachi. R, Pravinkumar S.E, Dickey B.F. Complications of Cancer and their Treatment: Respiratory Complications. In: Holland-Frei Cancer Medicine e.7, 7. Ed(s) Donald W. Kufe, Robert C. Bast, William N. Hait, Waun Ki Hong, Raphael E. Pollock, Ralph R. Weichselbaum, James F. Holland, Emil Frei III. BC Decker: USA, 2150-2173, www.bcdecker.com/cm7, e-Book 2006. PMID: 1-55009-307-X.
6. Pravinkumar E. T-Cell Immunity and Sepsis, Immunity and Inflammation. In: Critical Care Focus. 10. Ed(s) Galley H.F. BMJ Publishing Group: London, United Kingdom, 65-76, 2003. PMID: 0-7279-1689-0.
7. Pravinkumar, S.E. Noninvasive Mechanical Ventilation in Acute Respiratory Failure due to Pandemic Influenza A H1N1 Infection. In: Noninvasive mechanical ventilation in high risk infections - Guidelines for equipment and healthcare protocols. Ed(s) A.M. Esquinas Rodriguez. Springer Europe: Spain. Submitted.

Letters to the Editor
1. Pravinkumar SE. Physician Practice Variation in Critical Care: A Stumbling Block. Crit Care Med 37(3):1178-1179, 3/2009. PMID: 19237963.
2. Pravinkumar SE. Drotrecogin Alfa (Activated): Surviving Sepsis by Chance. Am J Respir Crit Care Med 177(6):669, 3/2008. PMCID: PMC18316771.
3. Pravinkumar E. Balance of Inflammation in Sepsis. Am J Respir Crit Care Med 169(5):655-656, 3/2004. PMID: 14982827.
4. Pravinkumar E. Cardiovascular Management of Septic Shock. Crit Care Med 32(1):315, 1/2004. PMID: 14707616.
5. Pravinkumar E. Rate and Rhythm are Important in Critically Ill Patients. BMJ 327(7420):931-932, 10/2003. PMCID: PMC218857.
6. Pravinkumar E. Staging of Non-small Cell Lung Cancer with Integrated PET and CT. N Engl J Med 349(12):1188-1190, 9/2003. PMID: 14503543.
7. Pravinkumar E. Obesity in General Elective Surgery. Lancet 362(9383):576-578, 8/2003. PMID: 12932394.
8. Pravinkumar, E. Indicators of Sepsis and Organ Failure: An Elusive Zone. Chest 123. e-Pub 6/2003.

Last updated: 11/4/2011