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Susan M. Fischer, MS, PhD

Present Title & Affiliation

Primary Appointment

Professor, Department of Molecular Carcinogenesis, Science Park, University of Texas MD Anderson Cancer Center, Science Park, Smithville, TX

Dual/Joint/Adjunct Appointment

Adjunct Professor, Pharmacology, Nutritional Sciences, The University of Texas, Austin, TX

Office Address

The University of Texas MD Anderson Cancer Center
Science Park - Department of Molecular Carcinogenesis
1808 Park Road 1C - PO Box 389
Unit Number: 116
Smithville, TX 78957
Room Number: Lab 2
Phone: (512) 237-2482
Email: smfischer@mdanderson.org

Education & Training

Degree-Granting Education

1974 University of Wyoming, Laramie, WY, PHD, Physiology
1971 University of Wyoming, Laramie, WY, MS, Physiology
1969 High Point College, High Point, NC, BS, Biology

Postgraduate Training

9/1974-8/1976 Postdoctoral Fellowship, Department of Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, Dr. Charles Shaw

Experience/Service

Academic Appointments

Associate Professor, Department of Molecular Carcinogenesis, Science Park, University of Texas MD Anderson Cancer Center, Science Park, Smithville, TX, 9/1987-8/1993
Assistant Professor, Department of Molecular Carcinogenesis, Science Park, University of Texas MD Anderson Cancer Center, Science Park, Smithville, TX, 10/1982-8/1987
Permanent Research Staff, Cancer and Toxicology Program, Oak Ridge National Laboratory, Oak Ridge, TN, 7/1980-8/1982
Junior Staff, Cancer and Toxicology, Oak Ridge National Laboratory, Oak Ridge, TN, 9/1976-6/1980

Honors and Awards

2001-2006 Ashbel Smith Professorship, University of Texas MD Anderson Cancer Center
1997 Excellence in Cancer Prevention, finalist, Julie and Ben Rogers Award
1997 Outstanding Faculty Achievement Award in Cancer Prevention, The University of Texas at MD Anderson
1980 ICRETT Award, International Union Against Cancer
1974-1976 Postdoctoral Training Grant Fellow, NIH
1974 Summer Scholarship, American Cancer Society
1969-1973 Predoctoral Fellowship, NDEA

Selected Publications

Peer-Reviewed Original Research Articles

1. Tian J, Lambertz I, Berton TR, Rundhaug JE, Kiguchi K, Shirley SH, Digiovanni J, Conti CJ, Fischer SM, Fuchs-Young R. Transgenic insulin-like growth factor-1 stimulates activation of COX-2 signaling in mammary glands. Mol Carcinog 51(12):973-83, 12/2012. e-Pub 10/2011. PMID: 22006370.
2. Lago CU, Nowinski SM, Rundhaug JE, Pfeiffer ME, Kiguchi K, Hirasaka K, Yang X, Abramson EM, Bratton SB, Rho O, Colavitti R, Kenaston MA, Nikawa T, Trempus C, Digiovanni J, Fischer SM, Mills EM. Mitochondrial respiratory uncoupling promotes keratinocyte differentiation and blocks skin carcinogenesis. Oncogene 31(44):4725-31, 11/2012. e-Pub 1/2012. PMID: 22266853.
3. Surh I, Rundhaug JE, Pavone A, Mikulec C, Abel E, Simper M, Fischer SM. The EP1 receptor for prostaglandin E2 promotes the development and progression of malignant murine skin tumors. Mol Carcinog 51(7):553-64, 7/2012. e-Pub 7/2011. PMCID: PMC3270117.
4. Zuo X, Peng Z, Wu Y, Moussalli MJ, Yang XL, Wang Y, Parker-Thornburg J, Morris JS, Broaddus RR, Fischer SM, Shureiqi I. Effects of gut-targeted 15-LOX-1 transgene expression on colonic tumorigenesis in mice. J Natl Cancer Inst 104(9):709-16, 5/2012. e-Pub 4/2012. PMCID: PMC3341308.
5. Garza LA, Liu Y, Yang Z, Alagesan B, Lawson JA, Norberg SM, Loy DE, Zhao T, Hanz BB, Stanton DC, Carrasco L, Ahluwalia G, Fischer SM, FitzGerald GA, Cotsarelis G. Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Sci Transl Med 21(4):126-34, 3/2012. PMCID: PMC3319975.
6. Perez C, Parker-Thornburg J, Mikulec C, Kusewitt DF, Fischer SM, Digiovanni J, Conti CJ, Benavides F. SKHIN/Sprd, a new genetically defined inbred hairless mouse strain for UV-induced skin carcinogenesis studies. Exp Dermatol 21(3):217-20, 3/2012. PMID: 22379968.
7. Liu B, Willette-Brown J, Liu S, Chen X, Fischer SM, Hu Y. IKKa represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin. Cell Death Differ 18(12):1854-64, 12/2011. e-Pub 5/2011. PMCID: PMC3214909.
8. Fischer SM. Protein growth factors and cytokines are typically thought to drive the proliferative/invasive/survival hallmarks of cancer. Preface. Cancer Metastasis Rev 30(3-4):275-6, 12/2011. PMID: 22080287.
9. Rundhaug JE, Simper MS, Surh I, Fischer SM. The role of the EP receptors for prostaglandin E(2) in skin and skin cancer. Cancer Metastasis Rev 30(3-4):465-80, 12/2011. e-Pub 10/2011. PMCID: PMC3236828.
10. Fischer SM, Hawk ET, Lubet RA. Non-steroidal Anti-inflammatory Drugs and Coxibs In Chemoprevention: A Commentary Based Primarily on Animal Studies. Cancer Prev Res (Phila) 4(11):1728-35, 11/2011. e-Pub 7/2011. PMCID: PMC3208782.
11. Smith KA, Tong X, Abu-Yousif AO, Mikulec CC, Gottardi CJ, Fischer SM, Pelling JC. UVB radiation-induced -catenin signaling is enhanced by COX-2 expression in keratinocytes. Mol Carcinog. e-Pub 8/2011. PMID: 21853475.
12. Lashinger LM, Malone LM, McArthur MJ, Goldberg JA, Daniels EA, Pavone A, Colby JK, Smith NC, Perkins SN, Fischer SM, Hursting SD. Genetic reduction of insulin-like growth factor-1 mimics the anticancer effects of calorie restriction on cyclooxygenase-2-driven pancreatic neoplasia. Cancer Prev Res (Phila) 4(7):1030-40, 7/2011. e-Pub 5/2011. PMCID: PMC3131443.
13. Lashinger LM, Malone LM, Brown GW, Daniels EA, Goldberg JA, Otto G, Fischer SM, Hursting SD. Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer. Cancer Prev Res (Phila) 4(7):1041-51, 7/2011. e-Pub 5/2011. PMCID: PMC3131470.
14. Surh I, Rundhaug J, Pavone A, Mikulec C, Abel E, Fischer SM. Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression. Mol Carcinog 50(6):458-68, 6/2011. e-Pub 1/2011. PMID: 21268127.
15. Benavides F, Perez C, Blando J, Contreras O, Shen J, Coussens LM, Fischer SM, Kusewitt DF, Digiovanni J, Conti CJ. Protective role of cathepsin L in mouse skin carcinogenesis. Mol Carcinog. e-Pub 5/2011. PMCID: PMC3155742.
16. Blando JM, Carbajal S, Abel E, Beltran L, Conti C, Fischer S, DiGiovanni J. Cooperation between Stat3 and Akt signaling leads to prostate tumor development in transgenic mice. Neoplasia 13:254-265, 2011.
17. Xia X, Park E, Liu B, Willette-Brown J, Gong W, Wang J, Mitchell D, Fischer SM, Hu Y. Reduction of IKKalpha expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis. Am J Pathol 176(5):2500-8, 5/2010. e-Pub 3/2010. PMCID: PMC2861114.
18. Ishikawa TO, Kumar IP, Machado HB, Wong KP, Kusewitt D, Huang SC, Fischer SM, Herschman HR. Positron emission tomography imaging of DMBA/TPA mouse skin multi-step tumorigenesis. Mol Oncol 4(2):119-25, 4/2010. e-Pub 2/2010. PMCID: PMC2838935.
19. Rundhaug JE, and Fischer SM. Molecular Mechanisms of Mouse Skin Tumor. Cancers 2(2):436-482, 2010. PMCID: PMC3033564.
20. Shen J, Fischer SM. Molecular profiling of the epidermis: a proteomics approach. Methods Molec Biol. 585:225-252, 2010.
21. Cekanova M, Lee SH, Donnell RL, Sukhthankar M, Eling TE, Fischer SM, Baek SJ. Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice. Cancer Prev Res (Phila Pa) 2(5):450-8, 5/2009. PMCID: PMC2697576.
22. Zuo X, Peng Z, Moussalli MJ, Morris JS, Broaddus RR, Fischer SM, Shureiqi I. Targeted genetic disruption of peroxisome proliferator-activated receptor-delta and colonic tumorigenesis. J Natl Cancer Inst 101(10):762-7, May 12, 5/2009. PMCID: PMC2684551.
23. Zhu F, Park E, Liu B, Xia X, Fischer SM, Hu Y. Critical role of IkappaB kinase alpha in embryonic skin development and skin carcinogenesis. Histol Histopathol 24(2):265-71, 2/2009. PMID: 19085841.
24. Wang X, Colby JK, Rengel RC, Fischer SM, Clinton SK, Klein RD. Overexpression of cyclooxygenase-2 (COX-2) in the mouse urinary bladder induces the expression of immune- and cell proliferation-related genes. Mol Carcinog 48(1):1-13, 2009. PMID: 18444251.
25. Lubet AR, Fischer SM, Steele VE, Juliana MM, Desmond R, Grubbs CJ. Rosiglitazone, a PPAR gamma agonist: Potent promoter of hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers. Int J Cancer 123(10):2254-9, 11/2008. PMID: 18712722.
26. Liu B, Xia X, Zhu F, Park E, Carbajal S, Kiguchi K, DiGiovanni J, Fischer SM, Hu Y. IKKa is required to maintain skin homeostasis and prevent skin cancer. Cancer Cell 14(3):212-25, 9/2008. PMID: 18772111.
27. Yamaguchi K, Cekanova M, McEntee MF, Yoon JH, Fischer SM, Renes IB, Van Seuningen I, Baek SJ. Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor-dependent pathways. Mol Cancer Ther 7(9):2779-87, 9/2008. PMCID: PMC2597004.
28. Colby JK, Klein RD, McArthur MJ, Conti CJ, Kiguchi K, Kawamoto T, Riggs PK, Pavone AI, Sawicki J, Fischer SM. Progressive metaplastic and dysplastic changes in mouse pancreas induced by cyclooxygenase-2 overexpression. Neoplasia 10(8):782-96, 8/2008. PMCID: PMC2481568.
29. Ansari KM, Rundhaug JE, Fischer SM. Multiple signaling pathways are responsible for prostaglandin e2-induced murine keratinocyte proliferation. Mol Cancer Res 6(6):1003-16, 6/2008. NIHMSID: NIHMS82465.
30. Rundhaug JE, Fischer SM. Cyclo-oxygenase-2 plays a critical role in UV-induced skin carcinogenesis. Photochem Photobiol 84(2):322-9, Mar-Apr, 3/2008. PMID: 18194346.
31. Tseng-Rogenski S, Lee IL, Gebhardt D, Fischer SM, Wood C, Park JM, Liebert M. Loss of 15-hydroxyprostaglandin dehydrogenase expression disrupts urothelial differentiation. Urology 71(2):346-50, 2/2008. PMCID: PMC2474790.
32. Riedel SB, Fischer SM, Sanders BG, Kline K. Vitamin E analog, alpha-tocopherol ether-linked acetic acid analog, alone and in combination with celecoxib, reduces multiplicity of ultraviolet-induced skin cancers in mice. Anticancer Drugs 19(2):175-81, 2/2008. PMID: 18176114.
33. Wang X, Colby JK, Yang P, Fischer SM, Newman RA, Klein RD. The resistance to the tumor suppressive effects of COX inhibitors and COX-2 gene disruption in TRAMP mice is associated with the loss of COX expression in prostate tissue. Carcinogenesis 29(1):120-8, 1/2008. PMID: 17942462.
34. Rundhaug JE, Pavone A, Kim E, Fischer SM. The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent. Mol Carcinog 46(12):981-92, 12/2007. PMID: 17583568.
35. Ansari KM, Sung YM, He G, Fischer SM. Prostaglandin receptor EP2 is responsible for cyclooxygenase-2 induction by prostaglandin E2 in mouse skin. Carcinogenesis 28(10):2063-8, 10/2007. e-Pub 2/2007. PMID: 17277233.
36. Park E, Zhu F, Liu B, Xia X, Shen J, Bustos T, Fischer SM, Hu Y. Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas. Cancer Res 67(19):9158-68, 10/2007. PMID: 17909021.
37. Fischer SM, Pavone A, Mikulec C, Langenbach R, Rundhaug JE. Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis. Mol Carcinog 46(5):363-71, 5/2007. PMCID: PMC2243235.
38. Van Dross RT, Hong X, Essengue S, Fischer SM, Pelling JC. Modulation of UVB-induced and basal cyclooxygenase-2 (COX-2) expression by apigenin in mouse keratinocytes: role of USF transcription factors. Mol Carcinog 46(4):303-14, 4/2007. PMID: 17186551.
39. Shen JJ, Pavone A, Mikulec C, Hensley SC, Traner A, Chang TK, Person MD, Fischer SM. Protein expression profiles in the epidermis of cyclooxygenase-2 transgenic mice by 2-dimensional gel electrophoresis and mass spectrometry. J Proteome Res 6(1):273-86, 1/2007. PMID: 17203971.
40. Rundhaug JE, Mikulec C, Pavone A, Fischer SM. A role for cyclooxygenase-2 in ultraviolet light-induced skin carcinogenesis. Mol Carcinog 46(8):692-8, 2007. PMID: 17443745.
41. Akunda JK, Chun K-S, Sessoms AR, Tiano H, Lao H-C, Fischer SM, Langenback R. Cyclooxygenase-2 deficiency increases epidermal apoptosis and impairs recovery following acute UVB exposure. Mol Carcinog 46(5):354-62, 2007. PMID: 17238138.
42. Liu B, Park E, Zhu F, Bustos T, Liu J, Shen J, Fischer SM, Hu Y. A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas. Proc Natl Acad Sci U S A 103(46):17202-7, 11/2006. PMCID: PMC1859910.
43. Sung YM, He G, Hwang DH, Fischer SM. Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development. Oncogene 25:5507-16, 4/2006. PMID: 16607275.
44. He G, Sung YM, Fischer SM. Troglitazone induction of COX-2 expression is dependent on ERK activation in keratinocytes. Prostaglandins Leukot Essent Fatty Acids 74(3):193-7, 3/2006. PMID: 16446079.
45. Xu X, Cheepala S, McCauley E, Coombes K, Xiao L, Fischer SM, Clifford JL. Chemoprevention of skin carcinogenesis by phenylretinamides: retinoid receptor-independent tumor suppression. Clin Cancer Res 12(3 Pt 1):969-79, 2/2006. PMID: 16467112.
46. Zuo X, Wu Y, Morris JS, Stimmel JB, Leesnitzer LM, Fischer SM, Lippman SM, Shureiqi I. Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity. Oncogene 25(8):1225-41, 2/2006. PMCID: PMC1432095.
47. Gee J, Lee IL, Jendiroba D, Fischer SM, Grossman HB, Sabichi AL. Selective cyclooxygenase-2 inhibitors inhibit growth and induce apoptosis of bladder cancer. Oncol Rep 15(2):471-7, 2/2006. PMID: 16391871.
48. He G, Sung YM, Digiovanni J, Fischer SM. Thiazolidinediones inhibit insulin-like growth factor-i-induced activation of p70S6 kinase and suppress insulin-like growth factor-I tumor-promoting activity. Cancer Res 66(3):1873-8, 2/2006. PMID: 16452250.
49. Shureiqi I, Wu Y, Chen D, Yang XL, Guan B, Morris JS, Yang P, Newman RA, Broaddus R, Hamilton SR, Lynch P, Levin B, Fischer SM, Lippman SM. The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. Cancer Res 65(24):11486-92, 12/2005. PMCID: PMC1564070.
50. Sung YM, He G, Fischer SM. Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development. Cancer Res 65(20):9304-11, 10/2005. PMID: 16230392.
51. He G, Muga S, Thuillier P, Lubet RA, Fischer SM. The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin. Mol Carcinog 43(4):198-206, 8/2005. PMID: 15864802.
52. Ruddat VC, Whitman S, Klein RD, Fischer SM, Holman TR. Evidence for downregulation of calcium signaling proteins in advanced mouse adenocarcinoma. Prostate 64(2):128-38, 7/2005. PMID: 15666362.
53. Klein RD, Van Pelt CS, Sabichi AL, Dela Cerda J, Fischer SM, Furstenberger G, Muller-Decker K. Transitional cell hyperplasia and carcinomas in urinary bladders of transgenic mice with keratin 5 promoter-driven cyclooxygenase-2 overexpression. Cancer Res 65(5):1808-13, 3/2005. PMID: 15753378.
54. Kim E, Rundhaug JE, Benavides F, Yang P, Newman RA, Fischer SM. An antitumorigenic role for murine 8S-lipoxygenase in skin carcinogenesis. Oncogene 24(7):1174-87, 2/2005. PMID: 15558016.
55. Rundhaug JE, Hawkins KA, Pavone A, Gaddis S, Kil H, Klein RD, Berton TR, McCauley E, Johnson DG, Lubet RA, Fischer SM, Aldaz CM. SAGE profiling of UV-induced mouse skin squamous cell carcinomas, comparison with acute UV irradiation effects. Mol Carcinog 42(1):40-52, 2005. PMID: 15547921.
56. He G, Thuillier P, Fischer SM. Troglitazone inhibits cyclin D1 expression and cell cycling independently of PPARgamma in normal mouse skin keratinocytes. J Invest Dermatol 123(6):1110-9, 12/2004. PMID: 15610522.
57. Tang S, Bhatia B, Zhou J, Maldonado CJ, Chandra D, Kim E, Fischer SM, Butler AP, Friedman SL, Tang DG. Evidence that Sp1 positively and Sp3 negatively regulate and androgen does not directly regulate functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) gene expression in normal human prostate epithelial cells. Oncogene 23(41):6942-53, 9/2004. PMID: 15247906.
58. Yang P, Chan D, Felix E, Cartwright C, Menter DG, Madden T, Klein RD, Fischer SM, Newman RA. Formation and antiproliferative effect of prostaglandin E(3) from eicosapentaenoic acid in human lung cancer cells. J Lipid Res 45(6):1030-9, 6/2004. PMID: 14993240.
59. Christensen LA, Conti CJ, Fischer SM, Vasquez KM. Mutation frequencies in murine keratinocytes as a function of carcinogenic status. Mol Carcinog 40(2):122-33, 6/2004. PMID: 15170817.
60. Jerde TJ, Mellon WS, Fischer SM, Liebert M, Bjorling DE, Nakada SY. Suppression of 15-hydroxyprostaglandin dehydrogenase messenger RNA concentration, protein expression, and enzymatic activity during human ureteral obstruction. J Pharmacol Exp Ther 309(1):398-403, 4/2004. PMID: 14718596.
61. Kim E, Muga SJ, Fischer SM. Identification and characterization of a phorbol ester-responsive element in the murine 8S-lipoxygenase gene. J Biol Chem 279(12):11188-97, 3/2004. PMID: 14711820.
62. Juttner S, Cramer T, Wessler S, Walduck A, Gao F, Schmitz F, Wunder C, Weber M, Fischer SM, Schmidt WE, Wiedenmann B, Meyer TF, Naumann M, Hocker M. Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors. Cell Microbiol 5(11):821-34, 11/2003. PMID: 14531897.
63. Sabichi AL, Xu H, Fischer S, Zou C, Yang X, Steele VE, Kelloff GJ, Lotan R, Clifford JL. Retinoid receptor-dependent and independent biological activities of novel fenretinide analogues and metabolites. Clin Cancer Res 9(12):4606-13, 10/2003. PMID: 14555536.
64. Shureiqi I, Jiang W, Zuo X, Wu Y, Stimmel JB, Leesnitzer LM, Morris JS, Fan HZ, Fischer SM, Lippman SM. The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells. Proc Natl Acad Sci U S A 100(17):9968-73, 8/2003. PMCID: PMC187904.
65. Fischer SM, Conti CJ, Viner J, Aldaz CM, Lubet RA. Celecoxib and difluoromethylornithine in combination have strong therapeutic activity against UV-induced skin tumors in mice. Carcinogenesis 24(5):945-52, 5/2003. PMID: 12771040.
66. Houston KD, Copland JA, Broaddus RR, Gottardis MM, Fischer SM, Walker CL. Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma. Cancer Res 63(6):1221-7, 3/2003. PMID: 12649180.
67. Pahan K, Jana M, Liu X, Taylor BS, Wood C, Fischer SM. Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes. J Biol Chem 277(48):45984-91, 11/2002. PMCID: PMC2045648.
68. Thuillier P, Brash AR, Kehrer JP, Stimmel JB, Leesnitzer LM, Yang P, Newman RA, Fischer SM. Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors. Biochem J 366(Pt 3):901-10, 9/2002. PMCID: PMC1222830.
69. Yang P, Felix E, Madden T, Fischer SM, Newman RA. Quantitative high-performance liquid chromatography/electrospray ionization tandem mass spectrometric analysis of 2- and 3-series prostaglandins in cultured tumor cells. Anal Biochem 308(1):168-77, 9/2002. PMID: 12234478.
70. Bol DK, Rowley RB, Ho CP, Pilz B, Dell J, Swerdel M, Kiguchi K, Muga S, Klein R, Fischer SM. Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development. Cancer Res 62(9):2516-21, 5/2002. PMID: 11980643.
71. Tang S, Bhatia B, Maldonado CJ, Yang P, Newman RA, Liu J, Chandra D, Traag J, Klein RD, Fischer SM, Chopra D, Shen J, Zhau HE, Chung LW, Tang DG. Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells. J Biol Chem 277(18):16189-201, 5/2002. PMID: 11839751.
72. La E, Rundhaug JE, Pavone A, Fischer SM. Regulation of transcription of the intracellular interleukin-1 receptor antagonist gene by AP-1 in mouse carcinoma cells. Mol Carcinog 33(4):237-43, 4/2002. PMID: 11933077.
73. Sample D, Wargovich M, Fischer SM, Inamdar N, Schwartz P, Wang X, Do KA, Sinicrope FA. A dose-finding study of aspirin for chemoprevention utilizing rectal mucosal prostaglandin E(2) levels as a biomarker. Cancer Epidemiol Biomarkers Prev 11(3):275-9, 3/2002. PMID: 11895877.
74. Klein RD, Fischer SM. Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells. Carcinogenesis 23(1):217-21, 2002. PMID: 11756245.
75. Fischer SM. Is cyclooxygenase-2 important in skin carcinogenesis? J Environ Pathol Toxicol Oncol 21(2):183-91, 2002. PMID: 12086405.

Book Chapters

1. Rundhaug JE, Fischer SM. Cellular and molecular mechanisms of tumor promotion. In: Chemical Carcinogenesis. 14, Comprehensive Toxicologey, 2nd. Ed(s) McQueen. Elsevier Science: Oxford, 311-333, 2010.
2. Rundhaug JE, Fischer SM. Cyclooxygenase-2 signaling in squamous cell carcinomas. In: Signaling Pathways in Squamous Cancer. Ed(s) AB Glick and C van Waes. Springer: New York, NY, 131-147, 2010.
3. Shen J, Fischer SM. Molecular profiling of the epidermis: a proteomics approach. In: Methods Mol Biol. 585, 2nd, 225-52, 2010. ISBN: 19908007.

Last updated: 3/15/2013