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Thomas M. Guerrero, M.D., Ph.D.

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
Associate Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Associate Professor, Department of Computational and Applied Mathematics, Rice University, Houston, TX

Education & Training

Degree-Granting Education

1997 University of California Los Angeles, Drew/UCLA Medical Education Program, Los Angeles, CA, MD, Medicine
1994 University of California Los Angeles, Los Angeles, CA, PHD, Biomedical Physics

Board Certifications

6/2003 American Board of Radiology, Radiation Oncology

Selected Publications

Peer-Reviewed Original Research Articles
1. Castillo E, Castillo R, Zhang Y, Tapia R, Guerrero T. 2009 Compressible image registration for thoracic computed tomography images. Journal of Medical and Biological Engineering. In Press.
2. McCurdy M, McAleer M, Wei W, Ezhil M, Johnson V, Khan M, Baker J, Luo D, Ajani J, Guerrero TM. Induction and Concurrent Taxanes Enhances both the Pulmonary Metabolic Radiation Response and the Radiation Pneumonitis Response in Patients with Esophagus Cancer. Int J Radiat Oncol Biol Phys. In Press.
3. Castillo R, Castillo E, Guerra R, Johnson VE, McPhail T, Garg AK, Guerrero T. A framework for evaluation of deformable image registration spatial accuracy using large landmark point sets. Phys Med Biol 54(7):1849-1870, 2009.
4. Zhang X, Zhao K, Guerrero TM, McGuire S, Yaremko B, Komaki R, Cox J, Hui Z, Li Y, Newhauser W, Mohan R, Liao Z. 4D CT-based Treatment Planning for Intensity-Modulated Radiation Therapy and Proton Therapy for Distal Esophagus Cancer. Int J Radiat Oncol Biol Phys 72(1):278-287, 9/2008.
5. Zhang X, Zhao KL, Guerrero TM, McGuire SE, Yaremko B, Komaki R, Cox JD, Hui Z, Li Y, Newhauser WD, Mohan R, Liao Z. Four-dimensional computed tomography-based treatment planning for intensity-modulated radiation therapy and proton therapy for distal esophageal cancer. Int J Radiat Oncol Biol Phys 72(1):278-87, 9/2008. PMCID: PMC2610812.
6. Hart J, McCurdy M, Ezhil M, Wei W, Khan M, Luo D, Munden R, Johnson V, Guerrero TM. Radiation pneumonitis: Correlation of toxicity with the pulmonary metabolic radiation response. Int J Radiat Oncol Biol Phys 71(4):967-971, 7/2008.
7. Zhang G, Huang TC, Forster K, Lin KP, Ibbott, G, Fitzpatrick M, Starkschall G, Liao Z, Guerrero TM. Dose Mapping: Validation in 4D Dosimetry with Measurements and Application in Radiotherapy Follow-up Evaluation. Comput Methods Programs Biomed 90(1):25-37, 4/2008.
8. Zhang G, Huang TC Guerrero TM, Lin KP, Stevens C, Starkschall G, Forster K. The use of 3D optical flow method in mapping of 3D anatomical structure and tumor contours across 4D CT data. J Appl Clin Med Phys 9(1):2738, 2/2008.
9. Lu J, Guerrero T, Munro P, Jeung A, Chi P-C, Balter P, Zhu X, Mohan R, Pan T. Adaptive four-dimension cone-beam computed tomography. Med Phys 34:3520-3529, 2007.
10. Huang EH, Liao Z, Cox J, Guerrero T, Chang J, Jeter M, Borghero Y, Wei X, Fossella F, Herbst R, Moran C, Allen P, Komaki R. Comparison of outcomes for patients with unresectable locally advanced non-small-cell lung cancer treated with induction chemotherapy followed by concurrent chemoradiation versus concurrent chemoradiation alone. Int J Radiat Oncol Biol Phys 68:779-85, 2007.
11. Yaremko BP, Guerrero TM, McAleer MF, Bucci KM, Noyola-Martinez J, Nguyen LT, Balter PA, Guerra R, Komaki R, Liao ZX. Determination of respiratory motion for distal esophagus cancer using four-dimensional computed tomography. Int J Radiat Oncol Biol Phys 70:145-153, 2007.
12. Rice DC, Smythe R, Liao Z, Guerrero TM, Change JY, McAleer MF, Jeter MD, Correa AM, Vaporciyan AA, Liu HH, Komaki R, Forster KM, Stevens C. Dose-dependent pulmonary toxicity after postoperative intensity-modulated radiotherapy for malignant plueral mesothelioma. Int J Radiat Oncol Biol Phys 69:350-357, 2007.
13. Shioyama Y, Jang SY, Liu HH, Guerrero TM, Wang X, Gayed IW, Erwin WD, Liao Z, Chang JY, Jeter M, Yaremko BP, Borghero Y, Cox JD, Komaki R, Mohan R. Preserving functional lung using perfusion imaging and intensity-modulated radiation therapy for locally advanced non-small cell lung cancer. Int J Radiat Oncol Biol Phys 68:1349-1358, 2007.
14. Guerrero TM, Johnson V, Hart J, Pan T, Khan M, Luo D, Liao Z, Ajani J, Komaki R. Radiation Pneumonitis: Local Dose versus [18F]-Fluorodeoxyglucose Uptake Response in Irradiated Lung. Int J Radiat Oncol Biol Phys 68:1030-1035, 2007.
15. Yaremko B, Guerrero TM, Noyola-Martinez J, Lege D, Nguyen L, Balter P, Cox J, Komaki R. Reduction of normal lung irradiation in locally advanced non-small cell lung cancer patients using ventilation images for functional avoidance. Int J Radiat Oncol Biol Phys 68:562-571, 2007.
16. Guerrero T, Castillo R, Noyola-Martinez J, Torres M, Zhou X, Guerra R, Cody D, Komaki R, Travis E. Reduction of pulmonary compliance found with high-resolution computed tomography in irradiated mice. Int J Radiat Oncol Biol Phys 67:879-887, 2007. PMID: 17293238.
17. Fang LC, Komaki R, Allen P, Guerrero T, Mohan R, Cox JD. Comparison of outcomes for patients with medically inoperable Stage I non-small-cell lung cancer treated with two-dimensional vs. three-dimensional radiotherapy. Int J Radiat Oncol Biol Phys 66:108-116, 2006. PMID: 16904517.
18. Guerrero T, Sanders K, Castillo E, Zhang Y, Bidaut L, Pan T, Komaki R. Dynamic ventilation imaging from four-dimensional computed tomography. Phys Med Biol 51:777-791, 2006. PMID: 16467578.
19. Wang S, Liao ZX, Chen Y, Chang JY, Jeter J, Guerrero TM, Ajani J, Pham A, Swisher S, Allen PK, Cox JD, Komaki R. Esophagus cancer located at the neck or upper thorax treated with concurrent chemoradiation: A single institution experience. J Thor Oncol 1:1-7, 2006.
20. Guerrero T, Castillo R, Sanders K, Price R, Komaki R, Cody D. Novel method to calculate pulmonary compliance images in rodents from computed tomography acquired at constant pressures. Phys Med Biol 51:1101-1112, 2006. PMID: 16481680.
21. Huang TC, Zhang G, Guerrero TM, Starkschall g, Lin KP, Forster K. Semi-automated CT segmentation using optical flow and fourier interpolation techniques. Comput Methods Programs Biomed 84:124-134, 2006.
22. Fitzpatrick MJ, Starkschall G, Balter P, Antolak JA, Guerrero T, Nelson C, Keall P, Mohan R. A novel platform simulating irregular motion to enhance assessment of respiration-correlated radiation therapy procedures. J Appl Clin Med Phys 6:13-21, 2005. PMID: 15770194.
23. Liao Z, Komaki R, Milas L, Yuan C, Kies M, Chang JY, Jeter M, Guerrero T, Blumenschien G, Smith CM, Fosella F, Brown B, Cox J. A phase I clinical trial of thoracic radiotherapy and concurrent celecoxib for patients with unfavorable performance status inoperable/operable non-small cell lung cancer. Clin Cancer Res 11(9):3342-48, 2005.
24. Zhang Z, Liao Z, Jin J, Ajani J, Chang JY, Jeter M, Guerrero T, Stevens CW, Swisher S, Ho L, Yao J, Allen P, Cox JD, Komaki R. Dose-response relationship in locoregional control for patients with stage II-III esophageal cancer treated with concurrent chemotherapy and radiotherapy. Int J Radiat Oncol Biol Phys 61:656-664, 2005. PMID: 15708243.
25. Guerrero T, Zhang G, Segars W, Huang TC, Bilton S, Ibbott G, Dong L, Forster K, Lin KP. Elastic image mapping for 4-D dose estimation in thoracic radiotherapy. Radiat Prot Dosimetry 115:497-502, 2005. PMID: 16381774.
26. Chandra A, Guerrero TM, Liu HH, Tucker SL, Liao Z, Wang X, Murshed H, Bonnen MD, Garg AK, Stevens CW, Chang JY, Jeter MD, Mohan R, Cox JD, Komaki R. Feasibility of using intensity-modulated radiotherapy to improve lung sparing in treatment planning for distal esophageal cancer. Radiother Oncol 77:247-253, 2005. PMID: 16298001.
27. Zhu XR, Prado K, Liu HH, Guerrero TM, Jeter M, Liao Z, Rice D, Forster K, Stevens CW. Intensity-modulated radiation therapy for mesothelioma: impact of multileaf collimator leaf width and pencil beam size on planning quality and delivery efficiency. Int J Radiat Oncol Biol Phys 62:1525-1534, 2005. PMID: 16029815.
28. Guerrero T, Sanders K, Noyola-Martinez J, Castillo E, Zhang Y, Tapia R, Guerra R, Borghero Y, Komaki R. Quantification of regional ventilation from treatment planning CT. Int J Radiat Oncol Biol Phys 62:630-634, 2005. PMID: 15936537.
29. Ragan D, Starkschall G, McNutt T, Kaus M, Guerrero T, Stevens CW. Semiautomated four-dimensional computed tomography segmentation using deformable models. Med Phys 32:2254-2261, 2005. PMID: 16121580.
30. Keall PJ, Starkschall G, Shukla H, Forster KM, Ortiz V, Stevens CW, Vedam SS, George R, Guerrero T, Mohan R. Acquiring 4D thoracic CT scans using a multilice helical method. Phys Med Biol 49:2053-2067, 2004. PMID: 15214541.
31. Liu HH, Wang X, Dong L, Wu Q, Liao Z, Stevens CW, Guerrero TM, Komaki R, Cox JD, Mohan R. Dose and volume reduction for normal lung using intensity-modulated radiation therapy for advanced-stage non-small cell lung cancer. Int J Radiat Oncol Biol Phys 58:1268-1279, 2004. PMID: 15001272.
32. Murshed H, Liu HH, Liao Z, Barker JL, Wang X, Tucker SL, Chandra A, Guerrero T, Stevens C, Chang JY, Jeter M, Cox JD, Komaki R, Mohan R. Dose and volume reduction for normal lung using intensity-modulated radiotherapy for advanced-stage non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 58:1258-1267, 2004. PMID: 15001271.
33. Taylor NA, Liao ZX, Cox JD, Stevens C, Roth J, Walsh G, Chang JY, Guerrero T, Jeter M, Putnam J, Jr, Fossella FV, Allen P, Komaki R. Equivalent outcome of patients with clinical Stage IIIA non-small-cell lung cancer treated with concurrent chemoradiation compared with induction chemotherapy followed by surgical resection. Int J Radiat Oncol Biol Phys 58:204-212, 2004. PMID: 14697440.
34. Jin J, Liao Z, Zhang Z, Ajani J, Swisher S, Chang JY, Jeter M, Guerrero T, Stevens CW, Vaporciyan A, Putnam J Jr, Walsh G, Smythe R, Roth J, Yao J, Allen P, Cox JD, Komaki R. Induction chemotherapy improved outcomes of patients with resectable esophageal cancer who received chemoradiotherapy followed by surgery. Int J Radiat Oncol Biol Phys 60:427-436, 2004. PMID: 15380576.
35. Guerrero T, Zhang G, Huang TC, Lin KP. Intrathoracic tumour motion estimation from CT imaging using the 3D optical flow method. Phys Med Biol 49:4147-4161, 2004. PMID: 15470929.
36. Deng J, Guerrero TM, Hai J, Luxton G, Ma C-M. Source modeling and beam commissioning for a cyberknife system. Physics in Medicine & Biology 49:1689-1704, 2004.
37. Riley B, Garcia J, Guerrero T. The utilization of a 3-dimensional noncoplanar treatment plan to avoid pacemaker complications. Med Dosim 29:92-96, 2004. PMID: 15191754.
38. Ahamad A, Stevens CW, Smythe WR, Liao Z, Vaporciyan AA, Rice D, Walsh G, Guerrero T, Chang J, Bell B, Komaki R, Forster KM. Promising early local control of malignant pleural mesothelioma following postoperative intensity modulated radiotherapy (IMRT) to the chest. Cancer J 9:476-484, 2003. PMID: 14740977.
39. Guerrero TM, Ricci AR, Dahlbom M, Cherry SR, Hoffman EJ. Parallel image reconstruction for 3D PET from incomplete 2D projection data. Proceedings of the SPIE 1904:978-986, 1993.
40. Guerrero TM, Cherry SR, Dahlbom M, Ricci AR, Hoffman EJ. Fast implementation of 3D PET reconstruction using vector and parallel programming techniques. IEEE Trans Nucl Sci 40:1082-1086, 1992.
41. Hoffman EJ, Cutler PD, Guerrero TM, Digby WM, Mazziotta JC. Assessment of accuracy of PET utilizing a 3-D phantom to simulate the activity distribution of [18F]fluorodeoxyglucose uptake in the human brain. J Cereb Blood Flow Metab 11:A17-25, 1991. PMID: 1997482.
42. Guerrero TM, Hoffman EJ, Dahlbom M, Cutler PD, Hawkins RA, Phelps ME. Characterization of a whole body imaging technique for PET. IEEE Trans Nucl Sci 37:676- 680, 1990.
43. Hoffman EJ, Guerrero TM, Germano G, Digby WM, Dahlbom M. PET system calibration and corrections for quantitative and spatially accurate images. IEEE Trans Nucl Sci 36:1109-1112, 1989.

Last updated: 9/14/2009