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Yiping Shao, Ph.D.

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX

Research Interests

My Primary research interest is focused on the design, development and evaluation of state-of-art radionuclide imaging detectors, systems, and techniques that will significantly improve the image quality and expand the applications of nuclear medicine and molecular imaging and biological/functional image-guided radiation therapy applications. Currently, my lab is developing advanced PET and multi-modality instrumentations and methods for image-based adaptive proton therapy and image-guided preclinical radiation oncology studies.


Education & Training

Degree-Granting Education

1994 Kent State University, Kent, OH, PHD, Experimental Nuclear Physics
1993 Northwestern Polytechnic University, Fremont, CA, MA, Electrical Engineering
1985 Soochew University, Suzhou, Jiangsu, China, MA, Physics
1982 Soochew University, Suzhou, Jiangsu, China, BA, Physics

Postgraduate Training

4/1994-6/1996 Postdoctoral Fellow, Biomedical Imaging Physics, Crump Institute for Molecular Imaging, UCLA, Los Angeles, CA, Simon R. Cherry

Selected Publications

Peer-Reviewed Original Research Articles

1. Shao Y, Sun X, Lou K, Zhu XR, Mirkovic D, Poenisch F, Grosshans D. In-beam PET imaging for on-line adaptive proton therapy: an initial phantom study. Phys Med Biol 59(13):3373-88, 5/2014. PMID: 24874943.
2. Shao Y, Sun X, Lan KA, Bircher C, Lou K, Deng Z. Development of a prototype PET scanner with depth-of-interaction measurement using solid-state photomultiplier arrays and parallel readout electronics. Phys Med Biol 59(5):1223-38, 3/2014. PMCID: PMC4041601.
3. Bircher C, Shao Y. Investigation of crystal surface finish and geometry on single LYSO scintillator detector performance for depth-of-interaction measurement with silicon photomultipliers. Nucl Instrum Methods Phys Res A A 693:236 - 43, 11/2012. PMCID: PMC3475527.
4. Bircher C, Shao Y. Use of internal scintillator radioactivity to calibrate DOI function of a PET detector with a dual-ended-scintillator readout. Med Phys 39(2):777-87, 2/2012. PMCID: PMC3272069.
5. Sun X, Lan AK, Bircher C, Deng Z, Liu Y, Shao Y. Energy and Timing Measurement with Time-Based Detector Readout for PET Applications: Principle and Validation with Discrete Circuit Components. Nucl Instrum Methods Phys Res A A 641(1):128-135, 6/2011. PMCID: PMC3129980.
6. Deng Z, Lan AK, Sun X, Bircher C, Liu Y, Shao Y. Development of an Eight-channel time based readout ASIC for PET applications. IEEE Transaction on Nuclear Sciences 58(6):3212-18, 2011.
7. Shao Y, Yao R, Ma T. A novel method to calibrate DOI function of a PET detector with a dual-ended scintillator readout. Med Phys 35(12):5829-5840, 12/2008. PMID: 19175139.
8. Yao R, Ma T, Shao Y. Lutetium oxyorthosilicate (LSO) intrinsic active correction and minimal detectable target activity study for SPECT imaging with a LSO-based animal PET scanner. Phys. Med. Biol. 53:4399-4415, 2008. PMID: 18670052.
9. Shao Y. A new timing model for calculating the intrinsic timing resolution of a scintillator detector. Phys. Med. Biol. 52:1103-1117, 2007.
10. Shao Y. Initial experimental studies of using solid state photomultiplier for PET applications. Nucl. Inst. Meth. 2007.
11. Shao Y, Meadors K, Silverman RW, Farrell R, Cirignano L, Grazioso R, Shah KS, Cherry SR. Dual APD array readout of LSO crystals:optimization of crystal surface treatment. IEEE Trans. Nucl. Sci. 49:649-654, 2002.

Grant & Contract Support

Title: Road to PET Image-Based On-line Proton Beam Range Measurement
Funding Source: NIH/NCI
Role: Principal Investigator
Duration: 9/12/2014 - 8/31/2016
Title: In-Situ PET Imaging for Adaptive Proton Therapy
Funding Source: Cancer Prevention & Research Institute of Texas (CPRIT)
Role: Principal Investigator
Duration: 12/1/2011 - 5/30/2015

Last updated: 11/19/2014