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Yuan Ji, Ph.D.

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Bioinformatics and Computational Biology, Division of Quantitative Sciences, The University of Texas M. D. Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Associate Professor, Statistics, Rice University, Houston, TX

Education & Training

Degree-Granting Education

2003 University of Wisconsin-Madison, Madison, WI, PHD, Statistics
1999 University of Minnesota, Twin Cities, MN, MS, Biostatistics
1997 Fudan University, Shanghai, China, BA, Mathematics

Honors and Awards

2003 ENAR Student Award, International Biometric Society's Eastern North American Region (ENAR), Florida
2002 Merck Foundation Fellowship, Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison
2002 NSF Young Researcher Travel Grant, National Science Foundation
2002 Student Travel Award and the Charles Sampson Award, The 25th annual Midwest Biopharmaceutical Statistics Workshop, Muncie, Indiana
2002 Vilas Travel Fellowship, University of Wisconsin-Madison, Madison, Wisconsin
1996 International Mathematical Modeling Contest, Department of Mathematics, Fudan University, China
1995 National Mathematical Modeling Contest, Department of Mathematics, Fudan University, China

Selected Publications

Peer-Reviewed Original Research Articles
1. Berkova Z, Wang S, Wang S, Wise J, Maeng H, Ji Y, Samaniego F. Herpesvirus 8 K1 oncoprotein regulates apoptosis by binding Fas by its immunoglobulin-like domain. Journal of the National Cancer Institute. In Press.
2. Wang M, Oki Y, Pro B, Romaguera J, Rodriguez MA, Samaniego F, McLaughlin P, Hagemeister F, Neelapu S, Copeland A, Samuels BI, Loyer EM, Ji Y, Younes A. Phase II Study of Yttrium-90 (90Y)-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory Mantle Cell Lymphoma. Journal of Clinical Oncology. In Press.
3. Bekele BN, Li Y, Ji Y. Risk-group-specific dose finding based on an average toxicity score. Biometrics, 7/23/2009. e-Pub 7/23/2009. PMID: 19645698.
4. Hu B, Ji Y (corresponding author), Tsiu K-W. Bayesian estimation of inverse dose-response. Biometrics 64(4). e-Pub 7/2009.
5. Berkova Z, Wang S, Wise JF, Maeng H, Ji Y, Samaniego F. Mechanism of Fas signaling regulation by human herpesvirus 8 K1 oncoprotein. J Natl Cancer Inst 101(6). e-Pub 3/10/2009. PMCID: PMC2720696.
6. Ji Y, Bekele N. Adaptive randomization for multi-arm comparative clinical trials based on joint efficacy/toxicity outcomes. Biometrics. e-Pub 1/23/2009. PMID: 19173694.
7. Li Y, Bekele BN, Ji Y, Cook JD. Dose-schedule finding in phase I/II clinical trials using a Bayesian isotonic transformation. Stat Med 27(24):4895-4913, 10/2008. PMID: 18563789.
8. Ji Y, Lu Y, Mills GB. Bayesian models based on test statistics for multiple hypothesis testing problems. Bioinformatics 24(7):943-949, 2008. e-Pub 2/2008. PMID: 18245123.
9. Bekele BN, Ji Y, Shen Y, Thall PF. Monitoring late-onset toxicities in phase I trials using predicted risks. Biostatistics 9(3). e-Pub 12/2007. PMID: 18084008.
10. Ji Y, Li Y, Yin G. Bayesian dose-finding designs for phase I clinical trials. Statistica Sinica 17:531-47, 2007.
11. Ji Y, Yin G, Tsui K-W, Kolonin M, Sun J, Arap W, Pasqualini R, Do K-A. Bayesian mixture models for complex high-dimension count data. Applied Statistics 56:139-152, 2007.
12. Ji Y, Li Y, Nebiyou Bekele B. Dose-finding in phase I clinical trials based on toxicity probability intervals. Clin Trials 4(3):235-44, 2007. PMID: 17715248.
13. Zhang J, Ji Y, Zhang L. Extracting three-way gene interactions from microarray data. Bioinformatics 23(21):2903-2909, 2007. e-Pub 10/5/2007. PMID: 17921496.
14. Yin G, Li Y, Ji Y. Bayesian dose-finding in phase I/II clinical trials using toxicity and efficacy odds ratios. Biometrics 62(3):777-84, 9/2006. PMID: 16984320.
15. Ji Y, Tsui K-W, Kim KM. A two-stage empirical Bayes method for identifying differentially expressed genes. Computational Statistics and Data Analysis. 50:3592-604, 2006.
16. Ji Y, Coombes K, Zhang J, Wen S, Mitchell J, Pusztai L, Symmans WF, Wang J. RefSeq refinements of UniGene-based gene matching improve the correlation of expression measurements between two microarray platforms. Appl Bioinformatics 5(2):89-98, 2006. PMID: 16722773.
17. Kolonin MG, Sun J, Do KA, Vidal CI, Ji Y, Baggerly KA, Pasqualini R, Arap W. Synchronous selection of homing peptides for multiple tissues by in vivo phage display. FASEB J 20(7):979-81, 2006. e-Pub 3/2006. PMID: 16581960.
18. Ji Y, Tsui KW, Kim K. A novel means of using gene clusters in a two-step empirical Bayes method for predicting classes of samples. Bioinformatics 21(7):1055-61, 4/1/2005. e-Pub 10/28/2004. PMID: 15514000.
19. Ji Y, Wu C, Liu P, Wang J, Coombes KR. Applications of beta-mixture models in bioinformatics. Bioinformatics 21(9):2118-22, 2005. e-Pub 2/15/2005. PMID: 15713737.
20. Hu B, Bekele BN, Ji Y (corresponding author). Adaptive Dose Insertion in Early Phase Clinical Trials. Stat Med. Submitted.
21. Baladandayuthapani V, Ji Y, Morris J, Talluri R, Nieto-Barajas L. Bayesian Random Segmentation Models to Identify Shared Copy Number Aberrations for Array. JASA. Submitted.
22. Nieto-Barajas L, Mueller P, Ji Y, Lu Y, Mills, G. Time Series Dependent Dirichlet. Annals of Applied Statistics. Submitted.
23. Ji Y, Liu P, Li Y, Nebiyou BB. Unit probability mass - a calibration-free method for dose-finding oncology trials. Biometrics. Submitted.

Grant & Contract Support

Title: UT M. D. Anderson Cancer Center Lymphoma SPORE - (PC-D)
Funding Source: NIH/NCI
Role: Co-Core Leader
Principal Investigator: Anas Younes
Duration: 9/1/2009 - 8/31/2012
 
Title: Chemotherapy Resistance in Hispanic and African American Patients
Funding Source: Komen for the Cure Catalystic Award for Disparities
Role: Co-Investigator
Principal Investigator: Maria Gonzalez-Angulo
Duration: 7/29/2009 - 7/28/2012
 
Title: Bayesian models for cancer prognosis by integrating diverse types of data
Funding Source: NIH/NCI
Role: Principal Investigator
Duration: 9/15/2008 - 7/31/2013
 
Title: SPORE in Brain Cancer (PP-2)
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: W K Alfred Yung
Duration: 9/1/2008 - 8/31/2013
 
Title: Clinical Activity of MGCD-0103 in Hodgkin Lymphoma
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Anas Younes
Duration: 7/8/2008 - 6/30/2010
 
Title: Translational Development of Novel Vaccine Therapies (PC-A)
Funding Source: Leukemia and Lymphoma Society
Role: Co-Investigator
Principal Investigator: Larry Kwak
Duration: 10/1/2007 - 9/30/2012
 
Title: Cancer Center Support Grant -- Bioinformatics Shared Resource (PP-SR22)
Funding Source: NIH/NCI
Role: Collaborator
Principal Investigator: John Mendelsohn
Duration: 7/1/2003 - 6/30/2013

Last updated: 9/23/2009