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Zhifei Wen, Ph.D.

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Radiation Physics - Patient Care, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

2005 Stanford University, Stanford, CA, MS, Department of Electrical Engineering, Electrical Engineering
2005 Stanford University, Stanford, CA, PHD, Departments of Physics and Radiology, Physics
1999 University of Science and Technology of China, Hefei, China, BS, Physics

Postgraduate Training

2010-2011 Advanced Radiation Physics Fellowship, UTMD Anderson Cancer Center, Houston, TX, Dr. Narayan Sahoo
2008-2010 Medical Physics Residency, Depts of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, Dr. Chester Reft
2006-2008 Postdoctoral Research Associate, Radiology and Medical Physics, University of Wisconsin, Madison, WI

Board Certifications

5/2011 American Board of Radiology: Therapeutic Medical Physics

Honors and Awards

2005 Greenfield Award - Best paper of the year, Medical Physics
2004 Research Trainee Prize, RSNA
2004 Young Investigator Competition Award, AAMI
2003 Honorable Mention Poster Award, SPIE Medical Imaging Meeting
2002 Research Trainee Prize, RSNA
2001 Cum Laude Award, SCBT/MR

Selected Publications

Peer-Reviewed Original Research Articles

1. Wiersma RD, Wen Z, Sadinski M, Farrey K, Yenice KM. Development of a frameless stereotactic radiosurgery system based on real-time 6D position monitoring and adaptive head motion compensation. Phys Med Biol 55(2):389-401, 1/21/2010. e-Pub 12/17/2009. PMID: 20019403.
2. Xu G, Fitzgerald ME, Wen Z, Fain S, Alsop DC, Carroll T, Ries M, Rowley H, Sager M, Asthana S, Johnson SC, Carlsson CM. Atorvastatin therapy is associated with greater and faster cerebral hemodynamic response. Brain Imaging and Behavior(2):94-104, 2008.
3. Fahrig R, Ganguly A, Lillaney P, Bracken J, Rowlands JA, Wen Z, Yu H, Rieke V, Santos JM, Pauly KB, Sze DY, Frisoli JK, Daniel BL, Pelc NJ. Design, performance, and applications of a hybrid x-ray/MR system for interventional guidance. IEEE 96(3):468-480, 2008.
4. O'halloran RL, Wen Z, Homes JH, Fain SB. Iterative projection reconstruction of time-resolved images using highly-constrained back-projection (HYPR). Magnetic Resonance in Medicine 59(1):132-139, 2008.
5. Wen Z, Reeder SB, Pineda AR, Pelc NJ. Noise considerations of three point water-fat separation imaging methods. Medical Physics 35(8):3597-3606, 2008.
6. Wen Z, Fahrig R, Williams S, Pelc NJ. Shimming with permanent magnets for the x-ray detector in a hybrid x-ray/MR system. Med Physics 35(9):3895-3902, 2008.
7. Wen Z, Fahrig R, Conolly S, Pelc NJ. Investigation of electron trajectories of an x-ray tube in magnetic fields of MR scanners. Med Phys 34(6):2048-2058, 6/2007. PMID: 17654908.
8. Wen Z, Pelc NJ, Nelson WR, Fahrig R. Study of increased radiation when an x-ray tube is placed in a strong magnetic field. Medical Physics 34:408-418, 2007.
9. Reeder SB, Pineda AR, Wen Z, Shimakawa A, Yu H, Brittain JH, Gold GE, Beaulieu CH, Pelc NJ. Iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL): application with fast spin-echo imaging. Magn Reson Med 54(3):636-44, 9/2005. PMID: 16092103.
10. Ganguly A, Wen Z, Daniel BL, Butts K, Kee ST, Rieke V, Do HM, Pelc NJ, Fahrig R. Truly hybrid X-ray/MR imaging: toward a streamlined clinical system. Acad Radiol 12(9):1167-77, 9/2005. PMID: 16099685.
11. Wen Z, Fahrig R, Pelc NJ. Robust x-ray tubes for use within magnetic fields of MR scanners. Med Phys 32(7):2327-36, 7/2005. PMID: 16121589.
12. Fahrig R, Wen Z, Ganguly A, DeCrescenzo G, Rowlands JA, Stevens GM, Saunders RF, Pelc NJ. Performance of a static-anode/flat-panel x-ray fluoroscopy system in a diagnostic strength magnetic field: A truly Hybrid x-ray/MR imaging system. Med Phys 32(6):1775-1784, 6/2005. PMID: 16013735.
13. Pineda R, Reeder SB, Wen Z, Shimakawa A, Yu H, Brittain GE, Gold C, Beaulieu H, Pelc NJ. Crame='er-Rao bounds for 3point dixon imaging. Magnetic Resonance in Medicine 56:625-635, 2005.
14. Kee ST, Ganguly A, Daniel BL, Wen Z, Butts A, Shimikawa NJ. MR-guided transjugular intrahepatic portosystemic shunt creation with use of a hybrid radiography/MR system. Journal of Vascular and Interventional Radiology, 2005.
15. Reeder SB, Wen Z, Yu H, Pineda AR, Gold GE, Markl M, Pelc NJ. Multicoil Dixon chemical species separation with an iterative least-squares estimation method. Magn Reson Med 51(1):35-45, 1/2004. PMID: 14705043.
16. Fahrig R, Heit G, Wen Z, Daniel BL, Butts K, Pelc NJ. First use of a truly-hybrid X-ray/MR imaging system for guidance of brain biopsy. Acta Neurochir (Wien) 145(11):995-997, 11/2003. PMID: 14628205.
17. Fahrig R, Butts K, Wen Z, Saunders R, Kee ST, Sze DY, Daniel BL, Laerum F, Pelc NJ. Truly hybrid interventional MR/X-ray system: investigation of in vivo applications. Acad Radiol 8(12):1200-7, 12/2001. PMID: 11770916.
18. Fahrig R, Butts K, Rowlands JA, Saunders R, Stanton J, Stevens GM, Daniel BL, Wen Z, Ergun DL, Pelc NJ. A truly hybrid interventional MR/X-ray system: Feasibility demonstration. J Magn Reson Imaging 13(13):294-300, 2/2001. PMID: 11169837.


1. Wen Z, Sahoo N. A novel procedure to determine the dose output change with spread out Bragg peak width and range shift in passively scattered proton beams. AAPM, 2011.
2. Wu T, Wen Z, Yenice K. Assessment of dose calculation accuracy of a commercially available monte carlo algorithm for plan optimization using oblique electron fields at extended SSDs. Annual Meeting ASTRO, 2010.
3. Wen Z, Yenice K, Farrey K, Wiersma R. A feasibility study on frameless gated head stereotactic radiosurgery/radiotherapy via real-time optical position monitoring and adaptive head motion compensation. AAPM, 2009.
4. Wen Z, Yenice K, Farrey K, Wiersma R. Development of a gated frameless stereotactic radiosurgery/radiotherapy system with real-time 3D position monitoring and adaptive head motion compensation. Amer Soc for Therapeutic RadOnc, 2009.
5. Wen Z, Xu G, Carlsson CM, Johnson SC, Alsop D, Rowley H, Shin W, Carroll T, Fain SB. Cerebral perfusion comparison between arterial sp0in labeling and dynamic susceptibility contrast MRI in subjects at risk for alzheimer's disease. ASNR:190, 2007.
6. Wen Z, Vigen KK, Shin W, Carroll TJ, Fain SB. Optimization of arterial input function selection for cerebral perfusion imaging with quantitative blood vloume correction. ISMRM:Proc. 592, 2007.
7. Wen Z, Pelc NJ, Nelson WR, Fahrig R. Investigationof increase in radiation when an x-ray tube is place in a magnetic field. RSNA, 2005.
8. Reeder SB, Pineda AR, Yu H, Wen Z. Asymmetric echoes for optimal SNR performance of "dixon" water-fat separation with fast spin-echo imaging. RSNA, 2004.
9. Wen, Z Fahrig R, Ganguly A, Kee ST, Daniel BL, Butts K, Yu H, Pelc NJ. "Hybrid interventional Mr/x-ray system". Assoc Advan Med Instru Annual Conf & Expo, 2004.
10. Wen Z, Fahrig R, Pelc NJ. Permanent magnet shimming for the x-ray detector in a hybrid x-ray/MR system. ISMRM, 2004.
11. Wen Z, Reeder SB, Pineda AR, Glover GH, Pelc NJ. Noise performance study of symmetric three point dixon method. ISMRM, 2003.
12. Wen Z, Fahrig R, Pelc NJ. X-ray tube in parallel magnetic fields. SPIE 5030:972-979, 2003.
13. Reeder SB, Wen Z, Gold GE, Alley MT, Markl M, Pelc NJ. Multi-point dixon fat-water separation and steady-state free prcession. RSNA 225(p):313, 2002.
14. Wen Z, Fahrig R, Sun N, Wang S, Pelc NJ. X-ray tube for use in magnetic fields. ISMRM, 2002.
15. Fahrig R, Butts K, Wen Z, Kee ST, Sze DY, Hu B, Plec NJ. Initial In Vivo results from interventional procedures carried in a truly hybrid x-ray/MR imaging system. SCBT/MR, 2001.
16. Wen Z, Fahrig R, Pelc NJ. Investigation of electron trajectories of an x-ray tube in a magnetic field. ISMRM:2188, 2001.

Last updated: 2/13/2013