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Michalis Aristophanous

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Radiation Physics - Patient Care, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Instructor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

2008 University of Chicago, Chicago, IL, PHD, Medical Physics
2002 University College London, London, UK, BS, Physics with Medical Physics

Postgraduate Training

8/2008-2/2011 Postdoctoral, Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical, Boston, MA

Experience/Service

Academic Appointments

Postdoctoral Fellow, Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 8/2008-2/2011

Other Appointments/Responsibilities

Visiting Medical Physicist, Bank of Cyprus Oncology Center, Nicosia, Cyprus, 3/2011-5/2011

Honors and Awards

2008 SPIE Student Travel Grant Award, SPIE
2004 Young Investigator Award, AAPM Midwest Chapter Meeting, Chicago, IL
2002 Deans Fellowship, University of Chicago, Biological Sciences Division
2001 Summer Scholarship, Welcome Trust Foundation, London, UK

Professional Memberships

AAPM, American Association of Physicist in Medicine
Member, 2004-present
ASTRO, American Society for Therapeutic Radiology and Oncology
Associate Member, 2009-present
ESTRO, European Society for Therapeutic Radiology and Oncology
Member, 2010-present
SWAAPM, Southwest Chapter of AAPM
Member, 2011-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Aristophanous M, Yue Y, Yap JT, Killoran JH, Allen AM, Berbeco RI, Chen AB. Evaluating FDG uptake changes between pre and post therapy respirator gated PET scans. Radiotherapy and Oncology 102(3):377-382, 3/2012. e-Pub 1/2012.
2. Aristophanous M, Berbeco RI, Killoran JH, Yap JT, Sher DJ, Allen AM, Larson E, Chen AB. Clinical utility of 4D FDG-PET/CT scans in radiation treatment planning. Int J Radiat Oncol Biol Phys 82(1):e99-105, 1/2012. e-Pub 3/2011. PMID: 21377285.
3. Aristophanous M, Yap JT, Killoran JH, Chen AB, Berbeco RI. Four dimensional positron emission tomography: implications for dose painting of high uptake regions. Int J Radiat Oncol Biol Phys 80(3):900-908, 7/1/2011. e-Pub 10/13/2010. PMID: 20950956.
4. Yue Y, Aristophanous M, Rottmann J, Berbeco RI. 3-D fiducial motion tracking using limited MV projections in arc-therapy. Med Phys 38(6):3222-3231, 6/2011. PMID: 21815397.
5. Aristophanous M, Rottmann J, Court LE, Berbeco RI. EPID-guided 3D dose verification of lung SBRT. Med Phys 38(1):495-503, 1/2011. PMID: 21361218.
6. Court LE, Seco J, Lu XQ, Ebe K, Mayo C, Ionascu D, Winey B, Giakoumakis N, Aristophanous M, Berbeco R, Rottman J, Bogdanov M, Schofield D, Lingos T. Use of a realistic breathing lung phantom to evaluate dose delivery errors. Med Phys 37(11):5850-7, 11/2010. PMID: 21158297.
7. Rottmann J, Aristophanous M, Chen A, Court L, Berbeco R. A multi-region algorithm for markerless beams-eye view lung tumor tracking. Phys Med Biol 55(18):5585-5598, 9/21/2010. e-Pub 8/31/2010. PMID: 20808029.
8. Aristophanous M, Rottmann J, Park SJ, Nishioka S, Shirato H, Berbeco RI. Image guided adaptive gating of lung cancer radiotherapy: a computer simulation study. Phys Med Biol 55(15):4321-4333, 8/7/2010. e-Pub 7/20/2010. PMID: 20647609.
9. Aristophanous M, Penney BC, Pelizzari CA. The development and testing of a digital PET phantom for the evaluation of tumor volume segmentation techniques. Med Phys 35(7):3331-3342, 7/2008. PMID: 18697557.
10. Aristophanous M, Penney BC, Martel MK, Pelizzari CA. A Gaussian mixture model for definition of lung tumor volumes in positron emission tomography. Med Phys 34(11):4223-4235, 11/2007. PMID: 18072487.

Abstracts

1. Yue Y, ARistophanous M, Rottmann J, Killoran JH, Yap JT, Chen AB, Berbeco RI. Dosimetric evaluation of treatment deliverty for lung SBRT using respiratory gated PET and in-treatment imaging. AAPM Annual Meeting, Vancouver, Canada, 2011.
2. Berbeco RI, Aristophanous M, Rottmann J, Park SJ, Court LE, Chen AB. EPID-based verification of respiratory-gated radiotherapy for lung tumors without fiducials. Oral presentation. International Workshop on Portal Imaging, Leuven, Belgium, 2011.
3. Aristophanous M, Yue Y, Killoran JH, Yap JT, Dauten A, Chen AB, Berbeco RI. Evaluation of repeat respiratory gated PET scans for the assessment of treatment effectiveness. AAPM Annual Meeting, Vancouver, Canada, 2011.
4. Aristophanous M, Chen AB, Yap J, Killoran J, Park SJ, Berbeco RI. PET-guided dose painting for moving tumors of the lung: A preliminary analysis contrasting 3D and 4D scans. Oral presentation. Molecular Imaging in Radiation Oncology (MIRO), Brussels, Belgium, 2011.
5. Court LE, Seco J, Lu X, Ebe K, Mayo C, Ionascu D, Winey B, Giakoumakis N, Aristophanous M, Berbeco R, Rottmann J, Bogdanox M, Schofield D, Lingos T. A lifelike breathing phantom and model tumor for IGRT and 4D dose calculation applications. General poster presentation. AAPM Annual Meeting, Philadelphia, PA, 2010.
6. Rottmann J, Aristophanous M, Chen AB, Court LE, Berbeco RI. A multiregion algorithm for robust lung tumor tracking with portal image sequences. Oral presentation. AAPM Annual Meeting, Philadelphia, PA, 2010.
7. Aristophanous M, Rottmann J, Court LE, Berbeco RI. A superfluence approach for EPID-guided 3D dose verification. Moderated poster presentation. AAPM Annual Meeting, Philadelphia, PA, 2010.
8. Yang F, Aristophanous M, Yang D, Low DA, Lu W. Application of unsupervised spectral clustering in 3D for PET tumor segmentation: A digital phantom study. General poster. AAPM Annual Meeting, Philadelphia, PA, 2010.
9. Aristophanous M, Yap JT, Chen AB, Killoran JH, Berbeco RI. Deformations in tumor volumes and high uptake sub-volumes observed with 4D FDG-PET. Moderated poster presentation. AAPM Annual Meeting, Philadelphia, PA, 2010.
10. Berbeco RI, Aristophanous M, Rottmann J, Park SJ, Court LE, Chen AB. EPID-based verification of respiratory-gated radiotherapy for lung tumors without fiducials. Oral presentation. International Workshop on Portal Imaging, Leuven, Belgium, 2010.
11. Yue Y, Aristophanous M, Rottmann J, Berbeco RI. Fiducial localization with MV EPID imaging during a rapidarc therapy. Oral presentation. AAPM Annual Meeting, Philadelphia, PA, 2010.
12. Aristophanous M, Berbeco RI, Killoran JH, Yap JT, Sher DJ, Allen AM, Larson E, Chen AB. Investigation of the clinical utility of 4D FDG-PET/CT scans in radiation treatment planning. ASTRO Annual Meeting, San Diego, CA, 2010.
13. Court LE, Seco J, Lu X, Ebe K, Mayuo C, Ionascu D, Winey B, Giakoumakis N, Aristophanous M, Berbeco R, Rottmann J, Bogdanov M, Schofield D, Lingos T. Treatment of moving tumors; an inter-modality comparison under realistic clinical conditions. Oral presentation. AAPM Annual Meeting, Philadelphia, PA, 2010.
14. Aristophanous M, Park SJ, Killoran J, Chen AB, Yap J, Berbeco RI. A comparison between 4D and 3D PET-based tumor volume definition for lung cancer patients. Oral presentation. AAPM Annual Meeting, Anaheim, CA, 2009.
15. Aristophanous M, Rottmann J, Park SJ, Berbeco RI. Adaptive gating of radiotherapy treatment based on marker-less tracking of lung tumors with kV fluoroscopy. General poster. AAPM Annual Meeting, Anaheim, CA, 2009.
16. Berbeco RI, Aristophanous M, Rottmann J, Park SJ. Marker-less verification of respiratory-gated radiotherapy for lung cancer. General poster presentation. AAPM Annual Meeting, Anaheim, CA, 2009.
17. Rottmann J, Aristophanous M, Park SJ, Berbeco RI. Mutual information for beans-eye-view lung tumor tracking without radiopaque markers. Moderated poster presentation. AAPM Annual Meeting, Anaheim, CA, 2009.
18. Winey BA, Berbeco RI, Aristophanous M, Rottmann J, Court LE. Simutaneous RapidARC treatment 4D-CBCT verification. General poster presentation. AAPM Annual Meeting, Anaheim, CA, 2009.
19. Aristophanous M, Pelizzari CA. Use of a clinically relevant digital PET chest phantom to investigate the threshold required to define a PET-based target volume. General poster presentation. AAPM Annual Meeting, Houston, TX, 2008.
20. Aristophanous M, Martel MK, Penney BC, Pelizzari CA. Application of a Gaussian mixture model for the segmentation of lung tumors in positron emission tomography. Oral presentation. AAPM Annual Meeting, Orlando, FL, 2007.
21. Aristophanous M, Pelizzari CA. The development of a realistic digital PET lung phanom for the evaluation of tumor volume segmentation techniques. Oral presentation. AAPM Annual Meeting, Minnepolis, MN, 2007.
22. Aristophanous M, Martel MK, Pelizzari CA, Penney BC. Investigation of a 3D gradient based method for volume segmentation in positron emission tomography for radiation treatment planning. Moderated poster presentation. AAPM Annual Meeting, Seattle, WA, 2005.
23. Aristophanous M, Pelizzari C. 3D reconstruction from pilot view for CT based brachtherapy planning. Oral presentation. AAPM Annual Meeting, Pittsburgh, PA, 2004.
24. Armato S, Aristophanous M, Engelmann R, Croteau C, MacMahon H. Automated detection of pathologic change from temporal substraction images of the chest. Oral presentation. RSNA Annual Meeting, Chicago, IL, 2003.

Last updated: 10/30/2013