Boris Sepesi, M.D., F.A.C.S.
Department of Thoracic and Cardiovascular Surgery, Division of Surgery
About Dr. Sepesi
Dr. Boris Sepesi is an Associate Professor in the Department of Thoracic and Cardiovascular Surgery at the University of Texas MD Anderson Cancer Center. Dr. Sepesi was born in former Czechoslovakia and earned his medical degree with honors from Jagiellonian University Medical College in Krakow, Poland. He completed internship and residency in general surgery at the University of Rochester Medical Center in Rochester, New York, where he also spent a year as a research fellow studying clinical outcomes of esophageal cancer therapies and other esophageal diseases. He then completed a clinical fellowship in cardiothoracic surgery at MD Anderson Cancer Center/Methodist training program, where he mainly focused on the treatment and multidisciplinary management of patients with complex thoracic oncological diagnoses (lung cancer, esophageal cancer, mesothelioma, mediastinal and chest wall tumors). At MD Anderson, he has also served as chief administrative resident. Dr. Sepesi is certified by the American Board of Surgery.
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Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Thoracic and Cardiovascular Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
Dr. Sepesi’s research interests focus on therapy outcomes and translational research in esophageal and lung cancers.
Clinical Interests
Dr. Sepesi’s clinical focus is on surgical therapies of thoracic and upper gastro-intestinal malignancies, utilizing the full spectrum of endoscopic, minimally invasive, and traditional surgical approaches based on disease specific indications and multidisciplinary plans. To advance therapeutic results he also focuses on enrolling patients in clinical trials, and on participating in multidisciplinary conferences to establish the most optimal personalized treatment plan for every patient.
Education & Training
Degree-Granting Education
| 2004 | Jagiellonian University College of Medicine, Krakow, POL, MD, Medicine |
| 1999 | University of Colorado, Boulder, CO, USA, BA, Psychology |
Postgraduate Training
| 2011-2013 | Clinical Residency, Cardiothoracic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2009-2011 | Clinical Residency, General Surgery, University of Rochester Medical Center, Rochester, NY |
| 2008-2009 | Research Fellowship, Division of Thoracic and Foregut Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY |
| 2005-2008 | Intern and Resident, General Surgery, University of Rochester Medical Center, Rochester, NY |
| 2005-2005 | Intern, General Surgery, University of Colorado, Denver, CO |
| 2004-2005 | Intern, Internal Medicine, University of Colorado, Denver, CO |
Board Certifications
| 2014 | American Board of Thoracic Surgery |
| 2012 | Diplomat, American Board of Surgery |
Experience & Service
Academic Appointments
Assistant Professor, Department of Thoracic and Cardiovascular Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2019
Administrative Appointments/Responsibilities
Chief Administrative Resident, Department of Thoracic and Cardiovascular Surgery, UT MD Anderson Cancer Center, Houston, TX, 2011 - 2013
Other Appointments/Responsibilities
Member, UT MD Anderson Cancer Center Pulmonary Embolism Interest Group, Houston, TX, 2015 - Present
Team Member, UT MD Anderson Cancer Center New Patient Access Strategic Planning Team, Houston, TX, 2014 - Present
Committee Member, UT MD Anderson Cancer Center Division of Surgery Promotion and Tenure Committee, Houston, TX, 2014 - Present
Co-Chair of Membership Committee, International Thymic Malignancy Interest Group, Kisco, NY, 2014 - Present
Member, Graduate Medical Education Committee, University of Rochester Medical Center, Rochester, NY, 2009 - 2010
Member, Clinical Council, University of Rochester Medical Center, Rochester, NY, 2007 - 2008
Class President, Jagiellonian University College of Medicine, Krakow, 2004 - Present
Institutional Committee Activities
Member, UT MD Anderson Cancer Center Pleural Effusion Work Group, 2015 - Present
Member, UT MD Anderson Cancer Center Disease Site Liaison Thoracic Oncology, 2015 - Present
Member, UT MD Anderson Cancer Center Lung Cancer Moon Shot Program, 2013 - Present
Consultantships
Consultant, Cooper Health, Philidelphia, PA, 2018 - Present
Consultant, Banner Health / M.D. Anderson Cancer Center, Phoenix, AZ, 2016 - Present
Honors & Awards
| 2015 | Fellow, American College of Surgeons |
| 2010 | Ronald Belsey Esophageal Surgery Club, Cologne, Germany |
| 2008 | Stuber Scholarship, University of Rochester Medical Center, Rochester, NY |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Blumenthaler AN, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Strange CD, Antonoff MB. Preoperative Maximum Standardized Uptake Value Associated with Recurrence Risk In Early Lung Cancer. Ann Thorac Surg 113(6):1835-1844, 2022. e-Pub 2021. PMID: 34252403.
- Corsini EM, Mitchell KG, Zhou N, Bernatchez C, Forget MA, Haymaker CL, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Amaria RN, Jazaeri AA, Antonoff MB. Pulmonary resection for tissue harvest in adoptive tumor-infiltrating lymphocyte therapy: Safety and feasibility. J Surg Oncol 124(4):699-703, 2021. e-Pub 2021. PMID: 34057733.
- Mitchell KG, Farooqi A, Ludmir EB, Corsini EM, Zhang J, Sepesi B, Vaporciyan AA, Swisher SG, Heymach JV, Zhang J, Gomez DR, Antonoff MB. Improved Overall Survival With Comprehensive Local Consolidative Therapy in Synchronous Oligometastatic Non-Small-Cell Lung Cancer. Clin Lung Cancer 21(12):37-46, 2021. e-Pub 2019. PMID: 31447303.
- Corsini EM, Sepesi B. Commentary: Salvage Resection For Stage IIIA Lung Cancer In The Era Of Immunotherapy. Semin Thorac Cardiovasc Surg 32(1):160-161, 2020. e-Pub 2019. PMID: 31442490.
- Shewale JB, Correa AM, Brown EL, Leon Novelo LG, Nyitray AG, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Walsh GL, Roth J, Vaporciyan AA, Swisher SG, Sepesi B. Time Trends of Perioperative Outcomes in Early-Stage Non-Small Cell Lung Cancer Resection Patients. Ann Thorac Surg 109(2):404-411, 2020. e-Pub 2019. PMID: 31539514.
- Nelson DB, Niu J, Mitchell KG, Sepesi B, Hofstetter WL, Antonoff MB, Giordano SH, Mehran RJ, Rice DC. Persistent Opiod Use Among The Elderly After Lung Resection: A SEER-Medicare Study. Ann Thorac Surg 109(1):194-202, 2020. e-Pub 2019. PMID: 31445908.
- Mitchell KG, Ikoma N, Nelson DB, Maru DM, Erasmus JJ, Weston BR, Vaporciyan AA, Antonoff MB, Mehran RJ, Rice DC, Roth JA, Swisher SG, Sepesi B, Walsh GL, Correa AM, Das P, Blum MA, Badgwell BD, Hofstetter WL. Mediastinal Nodal Involvement After Neoadjuvant Chemoradiation For Siewert II/III Adenocarcinoma. Ann Thorac Surg 108(3):845-851, 2019. e-Pub 2019. PMID: 31102632.
- Nelson DB, Rice DC, Mitchell KG, Tsao AS, Gomez DR, Sepesi B, Mehran RJ. Return to Intended Oncologic Treatment After Surgery For Malignant Pleural Mesothelioma. J Thorac Cardiovasc Surg 158(3):924-929, 2019. e-Pub 2019. PMID: 31430846.
- Nelson DB, Mehran RJ, Mitchell KG, Rajaram R, Correa AM, Bassett RL, Antonoff MB, Hofstetter WL, Roth JA, Sepesi B, Swisher SG, Walsh GL, Vaporciyan AA, Rice DC. Robotic Assisted Lobectomy For Non-Small Cell Lung Cancer: A Comprehensive Institutional Experience. Ann Thorac Surg 108(2):370-376, 2019. e-Pub 2019. PMID: 31004583.
- Nelson DB, Mehran RJ, Mitchell KG, Correa AM, Sepesi B, Antonoff MB, Rice DC. Enhanced Recovery After Thoracic Surgery Is Associated With Improved Adjuvant Chemotherapy Completion For Non-Small Cell Lung Cancer. J Thorac Cardiovasc Surg 158(1):279-286.e1, 2019. e-Pub 2019. PMID: 31014665.
- Nelson DB, Rice DC, Mitchell KG, Tsao AS, Vaporciyan AA, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Gomez DR, Mehran RJ, Sepesi B. Defining The Role Of Adjuvant Radiotherapy For Malignant Pleural Mesothelioma: A Propensity-Matched Landmark Analysis Of the National Cancer Database. J Thorac Dis 11(4):1269-1278, 2019.
- Yu W, Tang C, Hobbs BP, Li X, Koay EJ, Wistuba II, Sepesi B, Behrens C, Rodriguez Canales J, Parra Cuentas ER, Erasmus JJ, Court KE, Change JY. Development and Validation of a Predictive Radiomics Model for Clinical Outcomes in Stage I Non-small Cell Lung Cancer. Int J Radiat Oncol Biol Phys 102(4):1090-1097, 2018. e-Pub 2017.
- Tsao AS, Lindwasser OW, Adjei AA, Adusumilli PS, Beyers M, Blumenthal GM, Bueno R, Burt BM, Carbone M, Dahlberg SE, de Perrot M, Fennell DA< Friedberg J, Gill RR, Gomez DR, Harpole DH Jr, Hassan R, Hesdorffer M, Hirsch FR, Hmeljak J, Kindler HL, Korn EK, Liu G, Mansfield AS, Nowak AK, Pass HI, Peikert T, Rimner A, Robinson BWS, Rosenzweig KE, Rusch VW, Salgia R, Sepesi B, Simone CB. Current And Future Management Of Malignant Mesothelioma: A Consensus Report From The National Cancer Institute Thoracic Malignancy Steering Committee, International Association For The Study Of Lung Cancer And Mesothelioma Applied Research Foundation. J Thorac Oncol 13(11):1655-1667, 2018. e-Pub 2018. PMID: 30266660.
- Nelson DB, Lapid DJ, Mitchell KG, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG, Roth JA, Antonoff MB. Perioperative Outcomes for Stage I Non-Small Cell Lung Cancer: Differences Between Men and Women. Ann Thorac Surg 106(5):1499-1503, 2018. e-Pub 2018. PMID: 30118712.
- Pezzi TA, Schwartz DL, Mohamed ASR, Welsh JW, Komaki RU, Hahn SM, Sepesi B, Pezzi CM, Fuller CD, Chung SG. Barriers to Combined-Modality Therapy for Limited-Stage Small-Cell Lung Cancer. JAMA Oncol 4(8):E174504, 2018. e-Pub 2018. PMID: 29302695.
- Nelson DB, Dhupar R, Katkhuda R, Correa A, Goltsov A, Maru D, Sepesi B, Antonoff M, Mehran RJ, Rice DC, Vaporciyan AA, Davila M, Davila R, Betancourt S, Ajani J, Hofstetter WL. Outcomes after endoscopic mucosal resection or esophagectomy for submucosal esophageal adenocarcinoma. J Thorac Cardiovasc Surg 156(1):406-413, 2018. e-Pub 2018. PMID: 29605441.
- Sepesi B, Nelson DB, Mitchell KG, Gibbons DL, Heymach JV, Vaporciyan AA, Swisher SG, Roszik J. Prognostic Value of PD-L1 mRNA Sequencing Expression Profile in Non-Small Cell Lung Cancer. Ann Thorac Surg 105(6):1621-1626, 2018. e-Pub 2018. PMID: 29510096.
- Shewale JB, Nelson DB, Rice DC, Sepesi B, Hofstetter WL, Mehran RJ, Vaporciyan AA, Walsh GL, Swisher SG, Roth J, Antonoff MB. Natural History of Ground Glass Lesions among Patients with Previous Lung Cancer. Ann Thorac Surg 105(6):1671-1677, 2018. e-Pub 2018. PMID: 29432718.
- Nelson DB, Rice DC, Niu J, Atay SM, Vaporciyan AA, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Tsao AS, Gomez DR, Giordano SH, Mehran RJ, Sepesi B. Predictors of Trimodality Therapy and Trends In Therapy for Malignant Pleural Mesothelioma. Eur J Cardiothorac Surg 53(5):960-966, 2018. e-Pub 2017. PMID: 29211849.
- Wang JF, Pu X, Zhang X, Chen K, Xi Y, Wang J, Mao X, Shang J, Heymach JV, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Meng QH, Shaw KR, Eterovic AK, Fang B. Variants With a Low Allele Frequency Detected in Genomic DNA Affect the Accuracy of Mutation Detectionin Cell-free DNA by Next-generation Sequencing. Cancer 124(5):1061-1069, 2018. e-Pub 2017. PMID: 29178133.
- Casecone T, Gold KA, Swisher SG, Liu DD, Fossella FV, Sepesi B, Pataer A, Weissferdt A, Kalhor N, Vaporciyan AA, Hofstetter WK, Wistuba II, Heymach JV, Kim ES, William WN Jr.. Induction Cisplatin Docetaxel Followed by Surgery and Erlotinib in Non-Small Cell Lung Cancer. Ann Thorac Surg 105(2):418-424, 2018. e-Pub 2017. PMID: 29217088.
- Meraz IM, Majidi M, Cao X, Lin H, Li L, Wang J, Baladandayuthapani V, Rice D, Sepesi B, Ji L, Roth JA. TUSC2 Immunogene Therapy Synergizes with Anti-PD-1 through Enhanced Proliferation and Infiltration of Natural Killer Cells in SyngeneicKras-Mutant Mouse Lung Cancer Models. Cancer Immunol Res 6(2):163-177, 2018. e-Pub 2018. PMID: 29339375.
- Tang C, Hobbs B, Amer A, Li X, Behrens C, Canales JR, Cuentas EP, Villalobos P, Fried D, Chang JY, Hong DS, Welsh JW, Sepesi B, Court L, Wistuba II, Koay EJ. Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer. Sci Rep 8(1):1922, 2018. e-Pub 2018. PMID: 29386574.
- Atay SM, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh G, Antonoff MB. Perioperative Outcomes of Patients Undergoing Lobectomy on Clopidogrel. Ann Thorac Surg 104(6):1821-1828, 2017. e-Pub 2017. PMID: 28987393.
- Nelson DB, Rice DC, Niu J, Atay S, Vaporciyan AA, Antonoff M, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Tsao A, Gomez D, Giordano SH, Mehran R, Sepesi B. Long-Term Survival Outcomes of Cancer-Directed Surgery for Malignant Pleural Mesothelioma: Propensity Score Matching Analysis. J Clin Oncol 35(29):3354-3362, 2017. e-Pub 2017. PMID: 28817374.
- Blum Murphy M, Xiao L, Patel VR, Maru DM, Correa AM, G Amlashi F, Liao Z, Komaki R, Lin SH, Skinner HD, Vaporciyan A, Walsh GL, Swisher SG, Sepesi B, Lee JH, Bhutani MS, Weston B, Hofstetter WL, Ajani JA. Pathological complete response in patients with esophageal cancer after the trimodality approach: The association with baseline variables and survival-The University of Texas MD Anderson Cancer Center experience. Cancer. e-Pub 2017. PMID: 28885712.
- Antonoff MB, Correa AM, Sepesi B, Nguyen QN, Walsh GL, Swisher SG, Vaporciyan AA, Mehran RJ, Hofstetter WL, Rice DC. Salvage pulmonary resection after stereotactic body radiotherapy: A feasible and safe option for local failure in selected patients. J Thorac Cardiovasc Surg 154(2):689-699, 2017. e-Pub 2017. PMID: 28495066.
- Sepesi B, Gold KA, Correa AM, Heymach JV, Vaporciyan AA, Roszik J, Dmitrovsky E, Liu X. The Influence of Body Mass Index on Overall Survival Following Surgical Resection of Non-Small Cell Lung Cancer. J Thorac Oncol 12(8):1280-1287, 2017. e-Pub 2017. PMID: 28552766.
- Reuben A, Gittelman RM, Gao J, Zhang J, Yusko E, Wu CJ, Wmerson R, Zhang J, Tipton CM, Li J, Quek K, Gopalakrishnan V, Chen R, Vence L, Cascone T, Vignali M, Fujimoto J, Rodriguez-Canales J, Parra ER, Little LD, Gumbs C, Corget MA, Federico L, Haymaker C, Behrens C, Benzeno S, Bernatchez C, Sepesi B, Gibbons DL. Wargo JA, William WN, Swisher SG, Heymach J, Robins H, Lee JJ, Sharma P, Allison JP, Futreal PA, Wistuba II, Zhang J. TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence. Cancer Discov(10):108-1097, 2017. PMID: 28733428.
- Bassuner JK, Rice DC, Antonoff MB, Correa AM, Walsh GL, Vaporciyan AA, Garg N, Sepesi B, Swisher SG, Hofstetter WL, Roth JA, Mehran RJ. Polytetrafluoroethylene or Acellular Dermal Matrix for Diaphragmatic Reconstruction?. Ann Thorac Surg 103(6):1710-1714, 2017. e-Pub 2017.
- Peters HL, Tripathi SC, Kerros C, Katayama H, Garber HR, St John LS, Federico L, Meraz IM, Roth JA, Sepesi B, Majidi M, Ruisaard K, Clise-Dwyer K, Roszik J, Gibbons DL, Heymach JV, Swisher SG, Bernatchez C, Alatrash G, Hanash S, Molldrem JJ. Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells. Cancer Immunol Res 5(4):319-329, 2017. e-Pub 2017. PMID: 28254787.
- Lasala JD, Tsai J, Rodriguez-Restrepo A, Atay SM, Sepesi B. Systolic anterior motion of the mitral valve-the mechanism of postural hypotension following left intrapericardial pneumonectomy. J Thorac Dis 9(4):E354-E357, 2017. PMID: 28523177.
- Sun B, Brooks ED, Komaki R, Liao Z, Jeter M, McAleer M, Balter PA, Welsh JD, O'Reilly M, Gomez D, Hahn SM, Sepesi B, Rice DC, Heymach JV, Chang JY. Long-Term Outcomes of Salvage Stereotactic Ablative Radiotherapy for Isolated Lung Recurrence of Non-Small Cell Lung Cancer: A Phase II Clinical Trial. J Thorac Oncol 12(6):983-992. e-Pub 2017. PMID: 28259750.
- Pezzi TA, Mohamed AS, Fuller CD, Blanchard P, Pezzi C, Sepesi B, Hahn SM, Gomez DR, Chun SG. Radiation Therapy is Independently Associated with Worse Survival After R0-Resextion for Stage I-II Non-small Cell Lung Cancer: An Analysis of the National Cancer Data Base. Ann Surg Oncol. e-Pub 2017. PMID: 28154950.
- Sepesi B, Cuentas EP, Canales JR, Behrens C, Correa AM, Vaporciyan A, Weissferdt A, Kalhor N, Moran C, Swisher S, Wistuba I. Programmed Death Cell Ligand 1 (PD-L1) Is Associated With Survival in Stage I Non-Small Cell Lung Cancer. Semin Thorac Cardiovasc Surg 29(3):408-415, 2017. e-Pub 2017. PMID: 29195578.
- Parra ER, Behrens C, Rodriguez-Canales J, Lin H, Mino B, Blando J, Zhang J, Gibbons DL, Heymach JV, Sepesi B, Swisher SG, Weissferdt A, Kalhor N, Izzo J, Kadara H, Moran C, Lee JJ, Wistuba II. Image Analysis-Based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non-Small Cell Lung Carcinoma Patients. Clin Cancer Res 22(24):6278-6289, 2016. e-Pub 2016. PMID: 27252415.
- Gomez DR, Blumenschein GR, Lee JJ, Hernandez M, Ye R, Camidge DR, Doebele RC, Skoulidis F, Gaspar LE, Gibbons DL, Karam JA, Kavanagh BD, Tang C, Komaki R, Louie AV, Palma DA, Tsao AS, Sepesi B, William WN, Zhang J, Shi Q, Wang XS, Swisher SG, Heymach JV. Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line systemic therapy: a multicentre, randomised, controlled, phase 2 study. Lancet Oncol 17(12):1672-1682, 2016. e-Pub 2016. PMID: 27789196.
- Spicer JD, Shewale JB, Antonoff MB, Correa AM, Hofstetter WL, Rice DC, Vaporciyan AA, Mehran RJ, Walsh GL, Roth JA, Swisher SG, Sepesi B. The Influence of Reconstructive Technique on Perioperative Pulmonary and Infectious Outcomes Following Chest Wall Resection. Ann Thorac Surg 102(5):1653-1659, 2016. PMID: 27526650.
- Cata J, Jones J, Sepesi B, Mehran RJ, Rodreguez-Restrepo A, Lasala J, Feng L, Gottumukkala V. Lack of Association between Dexamethasone and Long-Term Survival After Non-Small Cell Lung Cancer Surgery. J Cardiotharac Anesth 30(4):930-5, 2016.
- Antonoff MB, Ragalie W, Correa AM, Spicer JD, Sepesi B, Roth JA, Walsh GL, Hofstetter WL, Swisher SG, Rice DC, Vaporciyan AA, Mehran RJ.. Results of Postdischarge Nursing Telephone Assessments: Persistent Symptoms Common Among Pulmonary Resection Patients. Ann Thorac Surg 102(1):276-81, 2016. e-Pub 2016.
- Sepesi B, Schmidt HE, Lada M, Correa AM, Walsh GL, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Ajani JA, Watson TJ, Swisher SG, Low DE, Hofstetter WL. Survival in Patients With Esophageal Adenocarcinoma Undergoing Trimodality Therapy Is Independent of Regional Lymph Node Location. Ann Thorac Surg 101(3):1075-81, 2016. e-Pub 2015. PMID: 26680311.
- Hassid VJ, Sepesi B. Chronic Osteomyelitis of the Manubrio-Clavicular Joint following Breast Augmentation. Plast Reconstr Surg 137(2):493e-4e, 2016. PMID: 26731586.
- Antonoff MB, Hofstetter WL, Correa AM, Bell JM, Sepesi B, Rice DC, Vaporciyan AA, Walsh GL, Mehran RJ, Swisher SG, Meyers BF. Clinical Prediction of Pathologic Complete Response in Superior Sulcus Non-Small-Cell Lung Cancer. Ann Thorac Surg 101(1):211-7, 2016. e-Pub 2015. PMID: 26279367.
- Hao C, Wang L, Peng S, Cao M, Li H, Hu J, Huang X, Liu W, Zhang H, Wu S, Pataer A, Heymach JV, Eterovic AK, Zhang Q, Shaw KR, Chen K, Futreal A, Wang M, Hofstetter W, Mehran R, Rice D, Roth JA, Sepesi B, Swisher SG, Vaporciyan A, Walsh GL, Johnson FM, Fang B. Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer. Cancer Lett 357(1):179-85, 2015. e-Pub 2014. PMID: 25444907.
- Francis AM, Correa AM, Betancourt-Cuellar SL, Kim JY, Sepesi B, Ajani JA, Komaki R, Erasmus J, Maru DM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Hofstetter WL, Swisher SG. Esophageal Tumor Thickness on Computed Tomography as a Predictor of Residual Tumor in Esophageal Adenocarcinoma Following Preoperative Chemoradiation. J Surg Res 186(2):680, 2014.
- Francis AM, Sepesi B, Correa AM, Blum MA, Erasmus JJ, Lee JH, Maru DM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Welsh JW, Swisher SG, Hofstetter WL, University of Texas MD Anderson Esophageal Cancer Group. The Influence of Histopathologic Tumor Viability on Long-term Survival and Recurrence Rates Following Neoadjuvant Therapy for Esophageal Adenocarcinoma. Ann Surg 258(3):500-7, 2013. PMID: 24022442.
- Wilshire CL, Salvador R, Sepesi B, Niebisch S, Watson TJ, Litle VR, Peyre CG, Jones CE, Peters JH. Reflux-associated oxygen desaturations: usefulness in diagnosing reflux-related respiratory symptoms. J Gastrointest Surg 17(1):30-8, 2013. e-Pub 2012. PMID: 23143640.
- Sepesi B, Swisher SG, Walsh GL, Correa A, Mehran RJ, Rice D, Roth J, Vaporciyan A, Hofstetter WL. Omental reinforcement of the thoracic esophagogastric anastomosis: an analysis of leak and reintervention rates in patients undergoing planned and salvage esophagectomy. J Thorac Cardiovasc Surg 144(5):1146-50, 2012. e-Pub 2012. PMID: 22939861.
- Sepesi B, Moalem J, Galka E, Salzman P, Schoeniger LO. The influence of staple size on fistula formation following distal pancreatectomy. J Gastrointest Surg 16(2):267-74, 2012. e-Pub 2011. PMID: 22015618.
- Gaur P, Sepesi B, Hofstetter WL, Correa AM, Bhutani MS, Watson TJ, Swisher SG, M. D. Anderson Esophageal Cancer Group, University of Rochester School of Medicine and Dentistry Foregut Group. Endoscopic esophageal tumor length: a prognostic factor for patients with esophageal cancer. Cancer 117(1):63-9, 2011. e-Pub 2010. PMID: 20803613.
- Dubecz A, Sepesi B, Salvador R, Polomsky M, Watson TJ, Raymond DP, Jones CE, Litle VR, Wisnivesky JP, Peters JH. Surgical resection for locoregional esophageal cancer is underutilized in the United States. J Am Coll Surg 211(6):754-61, 2010. e-Pub 2010. PMID: 20980174.
- Gaur P, Sepesi B, Hofstetter WL, Correa AM, Bhutani MS, Vaporciyan AA, Watson TJ, Swisher SG, Members of the MD Anderson Esophageal Cancer Group and the University of Rochester School of Medicine and Dentistry Foregut Group. A clinical nomogram predicting pathologic lymph node involvement in esophageal cancer patients. Ann Surg 252(4):611-7, 2010. PMID: 20881767.
- Polomsky M, Hu R, Sepesi B, O'Connor M, Qui X, Raymond DP, Litle VR, Jones CE, Watson TJ, Peters JH. A population-based analysis of emergent vs. elective hospital admissions for an intrathoracic stomach. Surg Endosc 24(6):1250-5, 2010. e-Pub 2009. PMID: 20033732.
- Sepesi B, Watson TJ, Zhou D, Polomsky M, Litle VR, Jones CE, Raymond DP, Hu R, Qiu X, Peters JH. Are endoscopic therapies appropriate for superficial submucosal esophageal adenocarcinoma? An analysis of esophagectomy specimens. J Am Coll Surg 210(4):418-27, 2010. PMID: 20347733.
- Polomsky M, Jones CE, Sepesi B, O'Connor M, Matousek A, Hu R, Raymond DP, Litle VR, Watson TJ, Peters JH. Should elective repair of intrathoracic stomach be encouraged?. J Gastrointest Surg 14(2):203-10, 2010. e-Pub 2009. PMID: 19957207.
- Sepesi B, Raymond DP, Polomsky M, Watson TJ, Litle VR, Jones CE, Hu R, Qiu X, Peters JH. Does the value of PET-CT extend beyond pretreatment staging? An analysis of survival in surgical patients with esophageal cancer. J Gastrointest Surg 13(12):2121-7, 2009. e-Pub 2009. PMID: 19795177.
- Polomsky M, Sepesi B, Litle VR, Raymond D, Jones CE, Watson TJ, Peters JH. The Clinical Significance of Elevated Esophageal Contraction Amplitudes: A High Resolution Manometric Study of "Nutcracker" Esophagus. Gastroenterology 136(5):A899, 2009.
- Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB, Bickford PC. Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines. J Neurosci 22(14):6114-20, 2002. PMID: 12122072.
Invited Articles
- Negrao MV, Quek K, Zhang J, Sepesi B. TRACERx: Tracking tumor evolution to impact the course of lung cancer. J Thorac Cardiovasc Surg 155(3):1199-1202, 2018. e-Pub 2017. PMID: 29331175.
- Sepesi B. Management of Breast Cancer Invading Chest Wall. Thorac Surg Clin 27(2):159-163, 2017. e-Pub 2017. PMID: 28363370.
- Sepesi B, Walsh GL. Surgical Therapy of Ground Glass Opacities. Semin Diagn Pathol 31(4):289-92, 2014. PMID: 25239273.
- Sepesi B, Peters JH. Current Anti-reflux Surgery. Current GERD Reports 1(4):233-240, 2007.
Other Articles
- Sepesi B Commentary: Surgery for N3 non-small cell lung cancer-utopia or future reality?. J Thorac Cardiovasc Surg 158(6):1693-1694, 2019. PMID: 31629501.
- Bloom BC, Augustyn A, Sepesi B, Patel S, Shah SJ, Komaki RU, Schild SE, Chun SG Prophylactic Cranial Irradiation Following Surgical Resection of Early-Stage Small-Cell Lung Cancer: A Review of the Literature. Front Oncol 7:228, 2017. PMID: 29034208.
- Hellmann MD, Chaft JE, William WN, Rusch V, Pisters KM, Kalhor N, Pataer A, Travis WD, Swisher SG, Kris MG, University of Texas MD Anderson Lung Cancer Collaborative Group Pathological response after neoadjuvant chemotherapy in resectable non-small-cell lung cancers: proposal for the use of major pathological response as a surrogate endpoint. Lancet Oncol 15(1):e42-50, 2014. PMID: 24384493.
- Sepesi B, Raymond DP, Peters JH Esophageal perforation: surgical, endoscopic and medical management strategies. Curr Opin Gastroenterol 26(4):379-83, 2010. PMID: 20473156.
Editorials
- Atay SM, Blub M, Sepesi B,. Adjuvant Chemotherapy Following Trimodality Therapy For Esophageal Carcinoma-Is The Evidence Sufficient?. J Thorac Dis 9(10):3626-3629, 2017.
- Sepesi B, Rice DC, Heymach JV, Vaporciyan AA, Swisher SG. Stage I Lung Cancer To Operate or To Radiate? That is the Question. J Thorac Dis 8(9):2324-2327, 2016. PMID: 27746966.
Abstracts
- Antonoff MB, Ragalie W, Correa AM, Spicer JD, Sepesi B, Roth JA, Walsh GL, Hofstetter WlL, Swisher SG, Rice DC, Vaporciyan AA, Mehran RJ. Indications For Counseling And Intervention After Pulmonary Resection: Results Of Post-discharge Nursing Telephone Assessments. Western Thoracic Surgical Association Annual Meeting 2015, 2015.
- Sepesi B, Schmidt HE, Lada M, Correa A, Walsh GL, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Ajani JA, Watson TJ, Swisher SG, Low DE, Hofstetter WL. Surgical Therapy Is An Important Multimodality Component in Patient with Distal Esophageal Adenocarcinoma Independent of Regional Lymph Node Location. STSA 2014, 2014.
- Sepesi B, Correa AM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Ajani JA, Walsh GL, Swisher SG, Hofstetter WL. Trends and Improving Outcomes in 882 Surgical Patients with Gastro-Esophageal Junction Adenocarcinoma - A Single Institution Experience. The International Society for Diseases of the Esophagus 2014, Vancouver, Canada, 2014.
- Sepesi B, Hofstetter WL, Rice DC, Mehran RJ, Vaporciyan AA, Walsh G, Roth JA, Swisher SG. Experience With Primary and Metastatic Adenoid Cystic Carcinoma. Society of Surgical Society 2014, 2014.
- Francis A, Correa A, Betancourt-Cuellar S, Kim J, Sepesi B, Ajani J, Komaki R, Erasmus J, Maru D, Munden RF, Mehran R, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Hofstetter WL, Swisher SG. Esophageal Tumor Thickness on Computed Tomography as a Predictor of Residual Tumor in Esophageal Adenocarcinoma Following Preoperative Chemoradiation. Academic Surgical Congress 2014, 2014.
- Francis AM, Sepesi B, Correa A, Mehran R, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Welsh J, Swisher SG, Hofstetter WL. Long-Term Survival and Recurrence Rates Following Trimodality Therapy of Esophageal Adenocarcinoma – The Influence of Histologic Tumor Viability. ASA 2013 Annual Meeting, 2013.
- Sepesi B, Correa A, Pataer A, Kalhor N, Bekele NB, Erasmus JJ, Hofstetter WL; Kim E, Komaki R, Mehran RJ, Moran CA, Papadimitrakopoulou V, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, William W, Wistuba I, Swisher SG.. The Impact of Histopathologic Response on Pathologic TNM Lung Cancer Staging System (AJCC 7th) Following Neoadjuvant Chemotherapy. STS 49th Annual Meeting, Los Angeles, CA, 2013.
- Sepesi B, Swisher SG, Walsh G, Correa A, Mehran R, Rice D, Roth J, Vaporciyan A, Hofstetter WL. Omental Reinforcement of the Thoracic Esophagogastric Anastomosis – An Analysis of Leak and Reintervention Rates in Planned and Salvage Esophagectomy Patients. Proc Am Assoc Thorac Surg, 2012.
- Wilshire CL, Salvador R, Sepesi B, Niebisch S, Watson TJ, Litle VR, Peyre CG, Jones CE, Peters JH. A Novel Method for the Diagnosis of Reflux-Related Respiratory Symptoms: Normalization of Reflux-Associated Oxygen Desaturations Following Nissen Fundoplication and Establishment of Normal Values. Gastroenterology 142(5):S1033, 2012.
- Wilshire CL, Salvador R, Sepesi B, Niebisch S, Watson TJ, Litle VR, Peyre CG, Jones CE, Peters JH. Reflux-Associated Oxygen Desaturations: Reliability in Diagnosing Reflux-Related Respiratory Symptoms. Digestive Disease Weekly, 2012.
- Sepesi B, Moalem J, Galka E, Salzman P, Schoeniger LO.. The Influence of Staple Size on Fistula Formation Following Distal Pancreatectomy. J Gastrointest Surg, 2011.
- Sepesi B, Watson TJ, Zhou D, Polomsky M, Litle VR, Jones CE, Raymond DP, Hu R, Qiu X, Peters JH. Are endoscopic therapies appropriate for superficial submucosal esophageal adenocarcinoma? An analysis of esophagectomy specimens. J Am Coll Surg 210(4):418-27, 2010.
- Gaur P, Sepesi B, Hofstetter WL, Correa AM, Bhutani MS, Ajani JA, Erasmus J, Komaki R, Lee JHL, Maru D, Mehran R, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Peters JH, Watson TJ, Swisher SG. A Clinical Nomogram Predicting Pathologic Lymph Node Involvement in Esophageal Cancer Patients. American Surgical Association 130th Annual Meeting 77, 2010.
- Polomsky M, Jones CE, Sepesi B, O'Connor M, Matousek A, Hu R, Raymond DP, Litle VR, Watson TJ, Peters JH.. Should elective repair of intrathoracic stomach be encouraged?. J Gastrointest Surg 14(2):203-10, 2010.
- Oppong BA, Choi D, Sepesi B, Skinner K. Re-evaluating Lobular Neoplasia and the Risk of Invasive and Intraductal Breast Cancers. The Breast Journal, 2010.
- Dubecz A, Sepesi B, Salvador R, Polomsky M, Watson TJ, Raymond DP, Jones CE, Litle VR, Wisnivesky JP, Peters JH. Surgical resection of locoregional esophageal cancer is underutilized in the United States. J Am College Surg 211(6):754-61, 2010.
- Sepesi B, Raymond DP, Polomsky M, Watson TJ, Litle VR, Jones CE, Hu R, Qiu X, Peters JH. Does the Value of PET-CT Extend Beyond Pretreatment Staging? An Analysis of Survival in Surgical Patients with Esophageal Cancer. Journal of Gastrointestinal Surgery 13(12):2121-2127, 2009.
- Polomsky M, Hu R, Sepesi B, O'Connor M, Qui X, Raymond DP, Litle VR, Jones CE, Watson TJ, Peters JH.. A population-based analysis of emergent vs. elective hospital admissions for an intrathoracic stomach. Surg Endosc, 2009.
Book Chapters
- Sepesi B, Raymond DP, Peters JH. The Management of Esophageal Perforation. In: Shackelford’s Surgery of the Alimentary Tract. 7th, 2012.
- Sepesi B, Peters JH. Esophageal Perforation. In: Clinical Decision Making in Gastroenterology and Hepatology, 2012.
- Sepesi B, Rice D. Mediastinal Lymphadenectomy. In: Mastery of Cardiothoracic Surgery, 2012.
- Sepesi B, Hofstetter WL. VATS In Staging and Diagnosis of Lung Cancer. In: Lung Cancer, 2012.
- Sepesi B. Surgical Approach: Patient Selection and Clinical Outcome. In: Personalized Management of Lung Cancer, 2012.
- Sepesi B, Peters JH. The Management of Barrett’s Esophagus. In: Current Surgical Therapy. 10th, 2010.
Letters to the Editor
- Nelson DB, Rice DC, Niu J, Mehran RJ Sepesi B. Reply to S.E. Vogl. J Clin Oncol.
- Sepesi B, Correa AM, Dmitrovsky E, Liu X. Reply to "Influence of Body Mass Index on Overall Survival Following Surgical Resection of Non-Small Cell Lung Cancer: Methodological Issues". J Thorac Oncol 12: e150-e151, 2017.
Grant & Contract Support
| Title: | NSCLC Patient-Derived Xenografts for Accelerating Development of Anti-Lung Cancer Drugs |
| Funding Source: | NIH/NCI |
| Role: | Co-Investigator |
| Title: | Evaluation of immunogene therapy in Kras mutated humanized patient derived xenografts (PDX) |
| Funding Source: | MD Anderson Cancer Center - Lung Cancer Moonshot |
| Role: | Co-Investigator |
| Title: | Pediatrics Ziopharm SIV Alliance - Research and Development Agreement |
| Funding Source: | Ziopharm Oncology |
| Role: | Co-Investigator |