
Diana Bell, M.D.
Department of Pathology, Division of Pathology and Laboratory Medicine
Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Head & Neck Surgery Department, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
1993 | University of Medicine and Pharmacy, Cluj-Napoca, ROM, MD, Medicine and Pharmacy |
Postgraduate Training
2007-2008 | Clinical Fellowship, Head And Neck Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX |
2006-2007 | Clinical Fellowship, Surgical Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX |
2002-2006 | Clinical Residency, Pathology, State University New York, Stony Brook, NY |
Board Certifications
2008 | Anatomic Pathology |
Experience & Service
Academic Appointments
Assistant Professor, Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2015
Assistant Professor, Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2008 - 2010
Institutional Committee Activities
Member, Clinical Research Protocols, 2019 - Present
Member, Faculty Senate, 2015 - Present
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Bell D, Bell AH, Kupferman ME, Prieto VG, Weber RS, Hanna EY. Comparative transcriptome analysis of sinonasal inverted papilloma and associated squamous cell carcinoma: Out-HOXing developmental genes. Head Neck 41(9):3090-3104, 2019. e-Pub 2019. PMID: 31041828.
- Ferrarotto R, Cardnell R, Su S, Diao L, Eterovic AK, Prieto V, Morrisson WH, Wang J, Kies MS, Glisson BS, Byers LA, Bell D. Poly ADP-ribose polymerase-1 as a potential therapeutic target in Merkel cell carcinoma. Head Neck 40(8):1676-1684, 2018. e-Pub 2018. PMID: 29570891.
- Bell D. Sinonasal Neuroendocrine Neoplasms: Current Challenges and Advances in Diagnosis and Treatment, with a Focus on Olfactory Neuroblastoma. Head Neck Pathol 12(1):22-30, 2018. e-Pub 2018. PMID: 29427030.
- Hanna EY, Abdelmeguid ASA, Roberts D, Bell AH, Weber RS, Bell D. Cellular subtype may predict survival outcomes in salivary adenoid cystic carcinoma patients-a single-institution experience. Virchows Arch 472(3):505-512, 2018. e-Pub 2017. PMID: 29063189.
- Bell AH, DeMonte F, Raza SM, Rhines LD, Tatsui CE, Prieto VG, Fuller GN, Bell D. Transcriptome comparison identifies potential biomarkers of spine and skull base chordomas. Virchows Arch 472(3):489-497, 2018. e-Pub 2017. PMID: 28844110.
- Bell D, Raza SM, Bell AH, Fuller GN, DeMonte F. Whole-transcriptome analysis of chordoma of the skull base. Virchows Arch 469(4):439-49, 2016. e-Pub 2016. PMID: 27401718.
- Esmaeli B, Yin VT, Hanna EY, Kies MS, William WN, Bell D, Frank SJ. Eye-sparing multidisciplinary approach for the management of lacrimal gland carcinoma. Head Neck 38(8):1258-62, 2016. e-Pub 2016. PMID: 27027275.
- Bell D, Bell AH, Bondaruk J, Hanna EY, Weber RS. In-depth characterization of the salivary adenoid cystic carcinoma transcriptome with emphasis on dominant cell type. Cancer 122(10):1513-22, 2016. e-Pub 2016. PMID: 26953815.
- Bell D, Sniegowski MC, Wani K, Prieto V, Esmaeli B. Mutational landscape of lacrimal gland carcinomas and implications for treatment. Head Neck 20(24078):10-1002, 2016. e-Pub 2015. PMID: 25899808.
- Bell D, Lewis C, El-Naggar AK, Weber RS. Primary intraosseous mucoepidermoid carcinoma of the jaw: Reappraisal of the MD Anderson Cancer Center experience. Head Neck 38 Suppl 1:E1312-7, 2016. e-Pub 2015. PMID: 26316332.
- Bell D, Hanna EY, Agaimy A, Weissferdt A. Reappraisal of sinonasal undifferentiated carcinoma: SMARCB1 (INI1)-deficient sinonasal carcinoma: a single-institution experience. Virchows Arch 467(6):649-656, 2015. e-Pub 2015. PMID: 26407663.
- Bell D, Ferrarotto R, Fox MD, Roberts D, Hanna EY, Weber RS, El-Naggar AK. Analysis and significance of c-MET expression in adenoid cystic carcinoma of the salivary gland. Cancer Biol Ther 29(6):1-5, 2015. e-Pub 2015. PMID: 25923130.
- Fonseca I, Bell A, Wani K, Bell D. Global transcriptome and sequenome analysis of formalin-fixed salivary epithelial-myoepithelial carcinoma specimens. Genes Chromosomes Cancer 54(4):249-59, 2015. e-Pub 2014. PMID: 25546727.
- Bell D, Saade R, Roberts D, Ow TJ, Kupferman M, DeMonte F, Hanna EY. Prognostic utility of Hyams histological grading and Kadish-Morita staging systems for esthesioneuroblastoma outcomes. Head Neck Pathol 9(1):51-9, 2015. e-Pub 2014. PMID: 24806334.
- Bell D, Hanna EY, Miele L, Roberts D, Weber RS, El-Naggar AK. Expression and significance of notch signaling pathway in salivary adenoid cystic carcinoma. Ann Diagn Pathol 18(1):10-3, 2014. e-Pub 2013. PMID: 24238845.
- Bell D, El-Naggar AK. Molecular Heterogeneity in Mucoepidermoid Carcinoma: Conceptual and Practical Implications. Head Neck Pathol 7(3):285-96, 2013. e-Pub 2013. PMID: 23459841.
- Bell D, Hanna EY. Sinonasal undifferentiated carcinoma: morphological heterogeneity, diagnosis, management and biological markers. Expert Rev Anticancer Ther 13(3):285-96, 2013. PMID: 23477516.
- Bell D, Hanna EY. Salivary Gland Cancers: Biology and Molecular Targets for Therapy. Curr Oncol Rep 14(14(2)):166-74, 2012. PMID: 22246609.
- Bell D, Bell A, Roberts D, Weber RS, El-Naggar AK. Developmental transcription factor EN1-a novel biomarker in human salivary gland adenoid cystic carcinoma*. Cancer 118(5):1288-92, 2012. e-Pub 2011. PMID: 21800291.
- Bell D, Roberts D, Karpowicz M, Hanna EY, Weber RS, El-Naggar AK. Clinical significance of Myb protein and downstream target genes in salivary adenoid cystic carcinoma. Cancer Biol Ther 12(7):569-73, 2011. e-Pub 2011. PMID: 21785271.
- Bell D, Holsinger CF, El-Naggar AK. CRTC1/MAML2 fusion transcript in central mucoepidermoid carcinoma of mandible--diagnostic and histogenetic implications. Ann Diagn Pathol 14(6):396-401, 2010. PMID: 21074686.
- Bell D, Roberts D, Kies M, Rao P, Weber RS, El-Naggar AK. Cell type-dependent biomarker expression in adenoid cystic carcinoma: biologic and therapeutic implications. Cancer 116(24):5749-56, 2010. e-Pub 2010. PMID: 20824717.
- Bell D, Kupferman ME, Williams MD, Rashid A, El-Naggar AK. Primary colonic-type adenocarcinoma of the base of the tongue: a previously unreported phenotype. Hum Pathol 40(12):1798-802, 2009. e-Pub 2009. PMID: 19695679.
- Bell D, Luna MA. Analysis of 2 cases of a distinct salivary neoplasm. Ann Diagn Pathol 13(3):201-7, 2009. e-Pub 2008. PMID: 19433301.
- Bell DM, Porras G, Tortoledo ME, Luna MA. Primary Sinonasal Choriocarcinoma. Ann Diagn Pathol 13(2):96-100, 2009. PMID: 19302957.
- Rao PH, Roberts D, Zhao YJ, Bell D, Harris CP, Weber RS, El-Naggar AK. Deletion of 1p32-p36 is the most frequent genetic change and poor prognostic marker in adenoid cystic carcinoma of the salivary glands. Clin Cancer Res 14(16):5181-5187, 2008. PMID: 18698036.
- Bell D, Luna MA, Weber RS, Kaye FJ, El-Naggar AK. CRTC1/MAML2 Fusion Transcript in Warthins Tumor and Mucoepidermoid Carcinoma: Evidence for a Common Genetic Association. Genes Chromosomes Cancer 47(4):309-314, 2008. PMID: 18181164.
- Nouri-Shirazi M, Banchereau J, Bell D, Burkeholder S, Kraus ET, Davoust J, Palucka KA. Dendritic cells capture killed tumor cells and present their antigens to elicit tumor-specific immune responses. J Immunol 165(7):3797-803, 2000. PMID: 11034385.
- Bell D, Chomarat P, Broyles D, Netto G, Harb GM, Lebecque S, Valladeau J, Davoust J, Palucka KA, Banchereau J. In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J Exp Med 190(10):1417-1426, 1999. PMID: 10562317.
- Bell D, Young JW, Banchereau J. Dendritic cells. Adv Immunol 72:255-324, 1999. PMID: 10361578.
- Ferrarotto R, Bell D, Rubin ML, Hutcheson KA, Johnson JM, Goepfert RP, Phan J, Elamin YY, Torman DK, Warneke CL, Hessel AC, Garden AS, Myers JN, Johnson FM, Lee JJ, Sikora AG, Gillison ML, Glisson BS, Gross ND. Impact of Neoadjuvant Durvalumab with or without Tremelimumab on CD8+ Tumor Lymphocyte Density, Safety, and Efficacy in Patients with Oropharynx Cancer: CIAO Trial Results. Clin Cancer Res. e-Pub 2020. PMID: 32269052.
- Liang L, Williams MD, Bell D. Expression of PTEN, Androgen Receptor, HER2/neu, Cytokeratin 5/6, Estrogen Receptor-Beta, HMGA2, and PLAG1 in Salivary Duct Carcinoma. Head Neck Pathol. e-Pub 2018. PMID: 30390196.
- Bell AH, Prieto VG, Ferrarotto R, Goepfert RP, Myers JN, Weber R, Bell D. Magnifying glass on spiradenoma and cylindroma histogenesis and tumorigenesis using systematic transcriptome analysis. Ann Diagn Pathol 41:14-23. e-Pub 2019. PMID: 31128548.
Abstracts
- Bell D, Bell AH. 6Ckine is a dominant chemokine in attracting mature dendritic cells in breast carcinoma. 2004 Annual USCAP Meeting 129(4):556, 2004.