Gary V. Martinez, Ph.D.
Department of Imaging Physics, Division of Diagnostic Imaging
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Imaging Physics - Research, Division of Diagnostic Imaging, MD Anderson Cancer Center, Houston, TX
Scientific Lead, Quantitative Pre-Clinical Imaging Group, Division of Basic Sciences, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
Education & Training
Degree-Granting Education
| 1997 | University of California, Santa Cruz, CA, USA, PHD, Biophysics |
| 1990 | CSU Long Beach, Long Beach, CA, USA, BS, Physics |
Postgraduate Training
| 1994-2004 | Post Doctoral, Department of Chemistry-University of Arizona, Tucson, AZ |
Experience & Service
Academic Appointments
Assistant Professor, University of South Florida, Tampa, FL, 2011 - 2018
Senior Research Scientist and Pre-clinical Imaging Facility manager, Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center & Research Metabolism, Tampa, FL, 2009 - 2018
Assistant Research Scientist, University of Arizona- Arizona Cancer Center, Tucson, AZ, 2004 - 2008
Institutional Committee Activities
Committee Member, Task Force for Core Technology Development, 2017 - Present
Host, Quantiative Imaging Group, 2010 - Present
Honors & Awards
| 2001 | NIH F32 National Research Service Award (NRSA),, University of Arizona |
| 1997 | Stipend, Swedish National Research Council |
| 1993 | NIH Predoctoral Fellowship (National Research Service Award), University of California Santa Cruz |
Selected Publications
Peer-Reviewed Articles
- Sanchez-Ramos J, Song S, Kong X, Foroutan P, Martinez G , Dominguez-Viqueria W, Mohapatra S, Mohapatra S, Haraszti RA, Khvorova A, Aronin N, Sava V. Chitosan-mangafodipir nanoparticles designed for intranasal delivery of sirna and dna to brain. J Drug Deliv Sci Technol 43:453-460, 2018. e-Pub 2017. PMID: 29805475.
- Bakewell SJ, Carie A, Costich TL, Sethuraman J, Semple JE, Sullivan B, Martinez GV, Dominguez-Viqueira W, Sill KN. Imaging the delivery of drug-loaded, iron-stabilized micelles. Nanomedicine 13(4):1353-1362, 2017. e-Pub 2017. PMID: 28115246.
- Trivikram R Molugu, Xiaolin Xu, Avigdor Leftin, Silvia Lope-Piedrafita, Gary V Martinez , Horia I Petrache, and Michael F Brown.. Solid-state deuterium nmr spectroscopy of membranes. Modern Magnetic Resonance, 2017.
- Huang Q, Schneeberger VE, Luetteke N, Jin C, Afzal R, Budzevich MM, Makanji RJ, Martinez GV , Shen T, Zhao L, Fung KM, Haura EB, Coppola D, Wu J. Preclinical Modeling of KIF5B-RET Fusion Lung Adenocarcinoma. Mol Cancer Ther 15(10):2521-2529, 2016. e-Pub 2016. PMID: 27496134.
- Zheng H, Zhao W, Yan C, Watson CC, Massengill M, Xie M, Massengill C, Noyes DR, Martinez GV , Afzal R, Chen Z, Ren X, Antonia SJ, Haura EB, Ruffell B, Beg AA. Hdac inhibitors enhance t-cell chemokine expression and augment response to pd-1 immunotherapy in lung adenocarcinoma. Clin Cancer Res 22(16):4119-4132, 2016. e-Pub 2016. PMID: 26964571.
- Enriquez-Navas PM, Kam Y, Das T, Hassan S, Silva A, Foroutan P, Ruiz E, Martinez G , Minton S, Gillies RJ, Gatenby RA. Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer. Sci Transl Med 8(327):327ra24-327ra24, 2016. PMID: 26912903.
- Qingling Huang, Valentina E Schneeberger, Noreen Luetteke, Roha Afzal, Mikalai M Budzevich, Rikesh Makanji, Gary Martinez , Domenico Coppola, and Jie Wu.. Characteristics, oncogene dependency, and response to ponatinib of a novel transgenic mouse model of kif5bret- induced lung adenocarcinoma. Journal of Thoracic Oncology 11(2:S54), 2016.
- Zhang X, Wojtkowiak JW, Martinez GV , Cornnell HH, Hart CP, Baker AF, Gillies R. MR Imaging Biomarkers to Monitor Early Response to Hypoxia-Activated Prodrug th-302 in Pancreatic Cancer Xenografts. PLoS One 11(5):e0155289, 2016. e-Pub 2016. PMID: 27227903.
Abstracts
- T. Mehnert, R. Bittman, Gary V. Martinez, M. F. Brown, F. Kamp, and K. Beyer. Biophysical Journal 88(1):70A-71A, 2005.
- Silvia Lope-Piedrafita, Gary V. Martinez, M. F. Brown, F. Kamp, and K. Beyer. Dynamical membrane stiffening by cholesterol on the mesoscale probed by deuterium NMR relaxation. Biophysical Journal 86(1):31A, 2004.
- Gary V. Martinez, Emily M. Dykstra, Silvia Lope-Piedrafita, Horia I. Petrache, and Michael F. Brown. Lanosterol and cholesterolinduced variations in bilayer elasticity studied by deuterium NMR and x-ray diffraction. Biophysical Journal 86(1):200A-200A, 2004.
- Gary V. Martinez, Martinez, Emily M. Dykstra, Silvia Lope-Piedrafita, and Michael F. Brown. Bilayer elasticity and its implications for the evolution of sterols as determined by 2H solid state NMR. Biophysical Journal 84(2):379A-379A, 2003.
Book Chapters
- Martinez GV. Introduction to MRI Physics. In: Methods Mol Biol, 3-19, 2018.
- Gary V Martinez. Introduction to MRI Physics. In: Preclinical MRI, 3-19, 2018.