Jianjun Shen, Ph.D.

Peer-Reviewed Articles

1. Liu C, Liu R, Zhang D, Deng Q, Liu B, Chao HP, Rycaj K, Takata Y, Lin K, Lu Y, Zhong Y, Krolewski J, Shen J, Tang DG MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes. Nat Commun 8:14270, 2017. e-Pub 2017. PMID: 28112170
2. Zhang D, Park D, Zhong Y, Lu Y, Rycaj K, Gong S, Chen X, Liu X, Chao HP, Whitney P, Calhoun-Davis T, Takata Y, Shen J, Iyer VR, Tang DG Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer. Nat Commun 7:10798, 2016. e-Pub 2016. PMID: 26924072
3. Rossi EL, de Angel RE, Bowers LW, Khatib SA, Smith LA, Van Buren E, Bhardwaj P, Giri D, Estecio MR, Troester MA, Hair BY, Kirk EL, Gong T, Shen J, Dannenberg AJ, Hursting SD Obesity-associated alterations in inflammation, epigenetics and mammary tumor growth persist in formerly obese mice. Cancer Prev Res (Phila) 9 (5) :339-48, 2016. e-Pub 2016. PMID: 26869351
4. Kim J, Zhao H, Dan J, Kim S, Hardikar S, Hollowell D, Lin K, Lu Y, Takata Y, Shen J, Chen T Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse. PLoS Genet 12 (4) :e1005970, 2016. e-Pub 2016. PMID: 27070551
5. Chen X, Li Q, Liu X, Liu C, Liu R, Rycaj K, Zhang D, Liu B, Jeter C, Calhoun-Davis T, Lin K, Lu Y, Chao HP, Shen J, Tang DG Defining a population of stem-like human prostate cancer cells that can generate and propagate castration-resistant prostate cancer (CRPC). Clin Cancer Res 22 (17) :4505-16, 2016. e-Pub 2016. PMID: 27060154
6. Wang Q, Trevino LS, Wong RL, Medvedovic M, Chen J, Ho SM, Shen J, Foulds CE, Coarfa C, O'Malley BW, Shilatifard A, Walker CL Reprogramming of the Epigenome by MLL1 Links Early-life Environmental Exposures to Prostate Cancer Risk. Mol Endocrinol 30 (8) :me20151310, 2016. e-Pub 2016. PMID: 27219490
7. Chitsazzadeh V, Coarfa C, Drummond JA, Nguyen T, Joseph A, Chilukuri S, Charpiot E, Adelmann CH, Ching G, Nguyen TN, Nicholas C, Thomas VD, Migden M, MacFarlane D, Thompson E, Shen J, Takata Y, McNiece K, Polansky MA, Abbas HA, Rajapakshe K, Gower A, Spira A, Covington KR, Xiao W, Gunaratne P, Pickering C, Frederick M, Myers JN, Shen L, Yao H, Su X, Rapini RP, Wheeler DA, Hawk ET, Flores ER, Tsai KY Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates Nat Commun 7:12601, 2016. e-Pub 2016. PMID: 27574101
8. Liu C, Eng C, Shen J, Lu Y, Takata Y, Mehdizadeh A, Chang GJ, Rodriguez-Bigas MA, Li Y, Chang P, Mao Y, Hassan MM, Wang F, Li D Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer. Oncotarget 7 (46) :76250-76260, 2016. e-Pub 2016. PMID: 27788488
9. Jeter CR, Liu B, Lu Y, Chao HP, Zhang D, Liu X, Chen X, Li Q, Rycaj K, Calhoun-Davis T, Yan L, Hu Q, Wang J, Shen J, Liu S, Tang DG NANOG reprograms prostate cancer cells to castration resistance via dynamically repressing and engaging the AR/FOXA1 signaling axis Cell Discov 2:16041, 2016. e-Pub 2016. PMID: 27867534
10. Liu X, Chen X, Rycaj K, Chao HP, Deng Q, Jeter C, Liu C, Honorio S, Li H, Davis T, Suraneni M, Laffin B, Qin J, Li Q, Yang T, Whitney P, Shen J, Huang J, Tang DG Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells. Oncotarget 6 (27) :23959-86, 2015. e-Pub 2015. PMID: 26246472
11. Abba MC, Gong T, Lu Y, Lee J, Zhong Y, Lacunza E, Butti M, Takata Y, Gaddis S, Shen J, Estecio MR, Sahin AA, Aldaz CM A Molecular Portrait of High-Grade Ductal Carcinoma In Situ. Cancer Res 75 (18) :3980-90, 2015. e-Pub 2015. PMID: 26249178
12. Boswell W, Boswell M, Titus J, Savage M, Lu Y, Shen J, Walter RB Sex-specific molecular genetic response to UVB exposure in Xiphophorus maculatus skin. Comp Biochem Physiol C Toxicol Pharmacol 178:76-85, 2015. e-Pub 2015. PMID: 26256120
13. Kim J, Singh AK, Takata Y, Lin K, Shen J, Lu Y, Kerenyi MA, Orkin SH, Chen T LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice. Nat Commun 6:10116, 2015. e-Pub 2015. PMID: 26626423
14. Li Y, Lu Y, Polak U, Lin K, Shen J, Farmer J, Seyer L, Bhalla AD, Rozwadowska N, Lynch DR, Butler JS, Napierala M Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus. Hum Mol Genet 24 (24) :6932-43, 2015. e-Pub 2015. PMID: 26401053
15. Liu B, Badeaux MD, Choy G, Chandra D, Shen I, Jeter CR, Rycaj K, Lee CF, Person MD, Liu C, Chen Y, Shen J, Jung SY, Qin J, Tang DG Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species. PLoS One 9 (3) :e90615, 2014. e-Pub 2014. PMID: 24598770
16. Simper MS, Rundhaug JE, Mikulec C, Bowen R, Shen J, Lu Y, Lin K, Surh I, Fischer SM The tumor promoting activity of the EP4 receptor for prostaglandin E2 in murine skin. Mol Oncol 8 (8) :1626-39, 2014. e-Pub 2014. PMID: 25034079
17. Xia X, Liu S, Xiao Z, Zhu F, Song NY, Zhou M, Liu B, Shen J, Nagashima K, Veenstra TD, Burkett S, Datla M, Willette-Brown J, Shen H, Hu Y An IKKα-Nucleophosmin Axis Utilizes Inflammatory Signaling to Promote Genome Integrity. Cell Rep 5 (5) :1243-1255, 2013. e-Pub 2013. PMID: 24290756
18. Benavides F, Perez C, Blando J, Contreras O, Shen J, Coussens LM, Fischer SM, Kusewitt DF, DiGiovanni J, Conti CJ Protective role of cathepsin L in mouse skin carcinogenesis. Mol Carcinog 51 (4) :352-61, 2012. PMID: 21538579
19. Wang-Johanning F, Rycaj K, Plummer JB, Li M, Yin B, Frerich K, Garza JG, Shen J, Lin K, Yan P, Glynn SA, Dorsey TH, Hunt KK, Ambs S, Johanning GL Immunotherapeutic potential of anti-human endogenous retrovirus-K envelope protein antibodies in targeting breast tumors. J Natl Cancer Inst 104 (3) :189-210, 2012. e-Pub 2012. PMID: 22247020
20. Shen J, Abel EL, Riggs PK, Repass J, Hensley SC, Schroeder LJ, Temple A, Chau A, McClellan SA, Rho O, Kiguchi K, Ward MD, Semmes OJ, Person MD, Angel JM, Digiovanni J Proteomic and pathway analyses reveal a network of inflammatory genes associated with differences in skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice Carcinogenesis 33 (11) :2208-19, 2012. e-Pub 2012. PMID: 22782996
21. Yan L, Della Coletta L, Powell KL, Shen J, Thames H, Aldaz CM, MacLeod MC Activation of the canonical Wnt/β-catenin pathway in ATF3-induced mammary tumors. PLoS One 6 (1) :e16515, 2011. e-Pub 2011. PMID: 21304988
22. Blando J, Moore T, Hursting S, Jiang G, Saha A, Beltran L, Shen J, Repass J, Strom S, DiGiovanni J Dietary energy balance modulates prostate cancer progression in hi-myc mice. Cancer Prev Res (Phila) 4 (12) :2002-14, 2011. PMID: 21952584
23. Jeter CR, Liu B, Liu X, Chen X, Liu C, Calhoun-Davis T, Repass J, Zaehres H, Shen JJ, Tang DG NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation. Oncogene 30 (36) :3833-45, 2011. e-Pub 2011. PMID: 21499299
24. Short JD, Dere R, Houston KD, Cai SL, Kim J, Bergeron JM, Shen J, Liang J, Bedford MT, Mills GB, Walker CL AMPK-Mediated Phosphorylation of Murine p27 at T197 Promotes Binding of 14-3-3 Proteins and Increases p27 Stability Mol Carcinog 49 (5) :429-39, 2010. e-Pub 2010. PMID: 20146253
25. Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL ATM Signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS Proc Natl Acad Sci U S A 107 (9) :4153-8, 2010. e-Pub 2010. PMID: 20160076
26. Kuang X, Shen J, Wong PK, Yan M Deregulation of mTOR signaling is involved in thymic lymphoma development in Atm-/- mice Biochem Biophys Res Commun 383 (3) :368-72, 2009. PMID: 19364503
27. Chan KS, Sano S, Kataoka K, Abel E, Carbajal S, Beltran L, Clifford J, Peavey M, Shen J, DiGiovanni J Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis Oncogene 27 (8) :1087-94, 2008. PMID: 17700521
28. Bhatia B, Multani AS, Patrawala L, Chen X, Calhoun-Davis T, Zhou J, Schroeder L, Schneider-Broussard R, Shen J, Pathak S, Chang S, Tang DG Evidence that senescent human prostate epithelial cells enhance tumorigenicity: Cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT Int J Cancer 122 (7) :1483-95, 2008. PMID: 18059027
29. Short JD, Houston KD, Dere R, Cai SL, Kim J, Johnson CL, Broaddus RR, Shen J, Miyamoto S, Tamanoi F, Kwiatkowski D, Mills GB, Walker CL AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27 Cancer Res 68 (16) :6496-506, 2008. PMID: 18701472
30. Yan M, Shen J, Person MD, Kuang X, Lynn WS, Atlas D, Wong PK Endoplasmic reticulum stress and unfolded protein response in Atm-deficient thymocytes and thymic lymphoma cells are attributable to oxidative stress Neoplasia 10 (2) :160-7, 2008. PMID: 18283338
31. Shen J, Riggs PK, Hensley SC, Schroeder LJ, Traner AR, Kochan KJ, Person MD, DiGiovanni J Differential expression of multiple anti-apoptotic proteins in epidermis of IGF-1 transgenic mice as revealed by 2-dimensional gel electrophoresis/mass spectrometry analysis Mol Carcinog 46 (5) :331-40, 2007. PMID: 17330866
32. Shen J, Pavone A, Mikulec C, Hensley SC, Traner A, Chang TK, Person MD Fischer SM Protein expression profiles in the epidermis of cyclooxygenase-2 transgenic mice by 2-dimensional gel electrophoresis and mass spectrometry J Proteome Res 6 (1) :273-86, 2007. PMID: 17203971
33. Yan M, Kuang X, Scofield VL, Shen J, Lynn WS, Wong PK The glucocorticoid receptor is increased in Atm-/- thymocytes and in Atm-/- thymic lymphoma cells, and its nuclear translocation counteracts c-myc expression Steroids 72 (5) :415-21, 2007. PMID: 17418878
34. Morrison AJ, Kim JA, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses Cell 130 (3) :499-511, 2007. PMID: 17693258
35. Zhu F, Xia X, Liu B, Shen J, Hu Y, Person M, Hu Y IKKalpha shields 14-3-3sigma, a G(2)/M cell cycle checkpoint gene, from hypermethylation, preventing its silencing Mol Cell 27 (2) :214-27, 2007. PMID: 17643371
36. Park E, Zhu F, Liu B, Xia X, Shen J, Bustos T, Fischer SM, Hu Y Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas Cancer Res 67 (19) :9158-68, 2007. PMID: 17909021
37. Cai SL, Tee AR, Short JD, Bergeron JM, Kim J, Shen J, Guo R, Johnson CL, Kiguchi K, Walker CL Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning J Cell Biol 173 (2) :279-89, 2006. PMID: 16636147
38. Liu B, Park E, Zhu F, Bustos T, Liu J, Shen J, Fischer SM, Hu Y A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas Proc Natl Acad Sci U S A 103 (46) :17202-7, 2006. PMID: 17079494
39. Person MD, Shen J, Traner A, Hensley SC, Lo HH, Abbruzzese JL, Li D Protein fragment domains identified using 2D gel electrophoresis/MALDI-TOF J Biomol Tech 17 (2) :145-56, 2006. PMID: 16741242
40. Jia Z, Person MD, Dong J, Shen J, Hensley SC, Stevens JL, Monks TJ, Lau SS Grp78 is essential for 11-deoxy-16,16-dimethyl PGE2-mediated cytoprotection in renal epithelial cells Am J Physiol Renal Physiol 287 (6) :F1113-22, 2004. PMID: 15226156
41. Soliman AS, Vulimiri SV, Kleiner HE, Shen J, Eissa S, Morad M, Taha H, Lukmanji F, Li D, Johnston DA, Lo HH, Lau S, DiGiovanni J, Bondy ML High levels of oxidative DNA damage in lymphocyte DNA of premenopausal breast cancer patients from Egypt Int J Environ Health Res 14 (2) :121-34, 2004. PMID: 15203457
42. Shen J, Person MD, Zhu J, Abbruzzese JL, Li D Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry Cancer Res 64 (24) :9018-26, 2004. PMID: 15604267
43. Liu JW, Shen JJ, Tanzillo-Swarts A, Bhatia B, Maldonado CM, Person MD, Lau SS, Tang DG Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration Oncogene 22 (10) :1475-85, 2003. PMID: 12629510
44. Kochan KJ, Wright DA, Schroeder LJ, Shen J, Morizot DC Genetic linkage maps of the West African clawed frog Xenopus tropicalis Dev Dyn 226 (1) :99-102, 2003. PMID: 12508229
45. Lopes EC, Garcia M, Benavides F, Shen J, Conti CJ, Alvarez E, Hajos SE Multidrug resistance modulators PSC 833 and CsA show differential capacity to induce apoptosis in lymphoid leukemia cell lines independently of their MDR phenotype Leukemia Research 27 (5) :413-23, 2003. PMID: 12620293
46. Yadav N, Lee J, Kim J, Shen J, Hu MC, Aldaz CM, Bedford MT Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice Proc Natl Acad Sci U S A 100 (11) :6464-8, 2003. PMID: 12756295
47. Li D, Firozi PF, Zhang W, Shen J, DiGiovanni J, Lau S, Evans D, Friess H, Hassan M, Abbruzzese JL DNA adducts, genetic polymorphisms and K-ras mutation in human pancreatic cancer. Mutation Research 513 (1-2) :37-48, 2002. PMID: 11719088
48. Tang S, Bhatia B, Maldonado CJ, Yang P, Newman RA, Liu J, Chandra D, Traag J, Klein RD, Fischer SM, Chopra D, Shen J, Zhau HE, Chung LW, Tang DG Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells Journal of Biological Chemistry 277 (18) :16189-201, 2002. PMID: 11839751
49. Vanzulli S, Efeyan A, Benavides F, Helguero LA, Peters G, Shen J, Conti CJ, Lanari C, Molinolo A p21, p27 and p53 in estrogen and antiprogestin-induced tumor regression of experimental mouse mammary ductal carcinoma Carcinogenesis 23 (5) :749-57, 2002. PMID: 12016147
50. Yan M, Kuang X, Qiang W, Shen J, Claypool K, Lynn WS, Wong PK Prevention of thymic lymphoma development in atm-/- mice by dexamethasone Cancer Res 62 (18) :5153-7, 2002. PMID: 12234978
51. Yan M, Qiang W, Liu N, Shen JJ, Lynn WS, Wong PK The ataxia-telangiectasia gene product may modulate DNA turnover and control cell fate by regulating cellular redox in lymphocytes Faseb J 15 (7) :1132-8, 2001. PMID: 11344081
52. Kiguchi K, Carbajal S, Chan K, Beltran L, Ruffino L, Shen J, Matsumoto T, Yoshimi N, DiGiovanni J Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma Cancer Res 61 (19) :6971-6, 2001. PMID: 11585718
53. Li D, Zhang W, Zhu J, Chang P, Sahin A, Singletary E, Bondy M, Hazra T, Mitra S, Lau S, Shen J, DiGiovanni J Oxidative DNA damage and 8-hydroxy-2-deoxyguanosine DNA glycosylase/apurinic lyase in human breast cancer Mol Carcinog 31 (4) :214-23, 2001. PMID: 11536371
54. Xu H, Shen J, Walker CL, Kleymenova E Tissue-specific expression and splicing of the rat polycystic kidney disease 1 gene DNA Seq 12 (5-6) :361-6, 2001. PMID: 11913782
55. Shen JJ, Matern D, Millington DS, Hillman S, Feezor MD, Bennett MJ, Qumsiyeh M, Kahler SG, Chen YT, Van Hove JL Acylcarnitines in fibroblasts of patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and other fatty acid oxidation disorders J Inherit Metab Dis 23 (1) :27-44, 2000. PMID: 10682306
56. Van Hove JL, Kahler SG, Feezor MD, Ramakrishna JP, Hart P, Treem WR, Shen JJ, Matern D, Millington DS Acylcarnitines in plasma and blood spots of patients with long-chain 3-hydroxyacyl-coenzyme A dehydrogenase defiency J Inherit Metab Dis 23 (6) :571-82, 2000. PMID: 11032332
57. Shaiu WL, Kishnani PS, Shen J, Liu HM, Chen YT Genotype-phenotype correlation in two frequent mutations and mutation update in type III glycogen storage disease. Mol Genet Metab 69 (1) :16-23, 2000. PMID: 10655153
58. Hadjigeorgiou GM, Comi GP, Bordoni A, Shen J, Chen YT, Salani S, Toscano A, Fortunato F, Lucchiari S, Bresolin N, Rodolico C, Piscaglia MG, Franceschina L, Papadimitriou A, Scarlato G Novel donor splice site mutations of AGL gene in glycogen storage disease type IIIa J Inherit Metab Dis 22 (6) :762-3, 1999. PMID: 10472540
59. Shen J, Liu HM, McConkie-Rosell A, and Chen YT Prenatal diagnosis for glycogen storage disease type IV, branching enzyme deficiency, using PCR-based DNA analysis Prenat Diagn 19 (9) :837-9, 1999. PMID: 10521841
60. Shen J, Liu HM, McConkie-Rosell A, Chen YT Prenatal diagnosis and carrier detection for glycogen storage disease type III using polymorphic DNA markers Prenat Diagn 18 (1) :61-4, 1998. PMID: 9483641
61. Parvari R, Shen J, Hershkovitz E, Chen YT, Moses SW Two new mutations in the 3' coding region of the glycogen debranching enzyme in a glycogen storage disease type IIIa Ashkenazi Jewish patient J Inherit Metab Dis 21 (2) :141-8, 1998. PMID: 9584265
62. Shen J, Bao Y, Chen YT A nonsense mutation due to a single base insertion in the 3'-coding region of glycogen debranching enzyme gene associated with a severe phenotype in a patient with glycogen storage disease type IIIa Hum Mutat 9 (1) :37-40, 1997. PMID: 8990006
63. Shen J, Liu HM, Bao Y, Chen YT Polymorphic markers of the glycogen debranching enzyme gene allowing linkage analysis in families with glycogen storage disease type III J Med Genet 34 (1) :34-8, 1997. PMID: 9032647
64. Parvari R, Moses S, Shen J, Hershkovitz E, Lerner A, Chen YT A single-base deletion in the 3'-coding region of glycogen-debranching enzyme is prevalent in glycogen storage disease type IIIA in a population of North African Jewish patients Eur J Hum Genet 5 (5) :266-70, 1997. PMID: 9412782
65. McConkie-Rosell A, Wilson C, Piccoli DA, Boyle J, DeClue T, Kishnani P, Shen JJ, Boney A, Brown B, Chen YT Clinical and laboratory findings in four patients with the non-progressive hepatic form of type IV glycogen storage disease J Inherit Metab Dis 19 (1) :51-8, 1996. PMID: 8830177
66. Shen J, Bao Y, Liu HM, Lee P, Leonard JV, Chen YT Mutations in exon 3 of the glycogen debranching enzyme gene are associated with glycogen storage disease type III that is differentially expressed in liver and muscle J Clin Invest 98 (2) :352-7, 1996. PMID: 8755644
67. Weeks JR, Hardin SE, Shen J, Lee JM, Greenleaf AL Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing Genes Dev 7 (12A) :2329-44, 1993. PMID: 8253380
68. Fan T, Li R, Todd NW, Qiu Q, Fang HB, Wang H, Shen J, Zhao RY, Caraway NP, Katz RL, Stass SA, Jiang F Up-regulation of 14-3-3Ƀ in lung cancer and its implication as prognostic and therapeutic target Cancer Res 67 (16) :7901-6. PMID: 17699796
69. Takata KI, Reh S, Yousefzadeh MJ, Zelazowski MJ, Bhetawal S, Trono D, Lowery MG, Sandoval M, Takata Y, Lu Y, Lin K, Shen J, Kusewitt DF, McBride KM, Cole F, Wood RD Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance. PLoS Genet 13 (6) :e1006818. e-Pub 2017. PMID: 28570559
70. Bae N, Viviano M, Su X, Lv J, Cheng D, Sagum C, Castellano S, Bai X, Johnson C, Khalil MI, Shen J, Chen K, Li H, Sbardella G, Bedford MT Developing Spindlin1 small-molecule inhibitors by using protein microarrays. Nat Chem Biol. e-Pub 2017. PMID: 28504676
71. Liu B, Gong S, Li Q, Chen X, Moore J, Suraneni MV, Badeaux MD, Jeter CR, Shen J, Mehmood R, Fan Q, Tang DG Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model. Oncotarget. e-Pub 2017. PMID: 28477021
72. Mao Y, Shen J, Lu Y, Lin K, Wang H, Li Y, Chang P, Walker MG, Li D RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer Oncotarget. e-Pub 2017. PMID: 28418924
73. Zhang D, Lin K, Lu Y, Rycaj K, Zhong Y, Chao HP, Calhoun-Davis T, Shen J, Tang DG Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer. Stem Cells Transl Med. e-Pub 2016. PMID: 27686757
74. Abba MC, Zhong Y, Lee J, Kil H, Lu Y, Takata Y, Simper MS, Gaddis S, Shen J, Aldaz CM DMBA Induced Mouse Mammary Tumors Display High Incidence of Activating Pik3caH1047 and Loss of Function Pten Mutations Oncotarget. e-Pub 2016. PMID: 27588403
75. Zhou F, Li M, Wei Y, Lin K, Lu Y, Shen J, Johanning GL, Wang-Johanning F Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells Oncotarget. e-Pub 2016. PMID: 27557521