Juan C. Lopez-Mattei, M.D., F.A.C.C., F.A.S.E., F.S.C.C.T., F.S.C.M.R.
Department of Cardiology, Division of Internal Medicine
About Dr. Lopez-Mattei
Juan C. Lopez-Mattei, MD is a Multimodality Imaging Cardiologist and Associate Professor of Cardiology and Diagnostic Imaging at The University of Texas MD Anderson Cancer Center where he co-directs the Cardiac Radiology Service (Cardiac CT & MRI). He is member of the editorial boards of Journal of Cardiovascular Magnetic Resonance & JACC: CardioOncology. Holds multiple leadership positions in several cardiovascular imaging societies, such as American Society of Echocardiography, Society of Cardiovascular Magnetic Resonance and Society of Cardiovascular Computed Tomography. Has been a speaker in multiple national and international cardiovascular meetings (ACC, SCCT, ASE, SCMR, SCAI, etc.) and has over 50 peer-reviewed publications in several topics in Cardio-Oncology (imaging, interventional, outcomes).
Present Title & Affiliation
Primary Appointment
Co-Director, Cardiac Radiology Services, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Associate Professor, Department of Cardiology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2005 | Ponce School of Medicine, Ponce, PR, PRI, MD, Medicine |
Postgraduate Training
| 2011-2013 | Clinical Fellowship, Cardiovascular Imaging (Level III Echocardiography, Cardiac Magnetic Resonance & Cardiac CT Fellowship), Houston Methodist Hospital- Weill Cornell, Houston, TX |
| 2008-2011 | Clinical Fellowship, Cardiovascular Disease, San Juan V.A. Medical Center, San Juan, PR |
| 2005-2008 | Clinical Residency, Internal Medicine, University of Puerto Rico School of Medicine, San Juan, PR |
Board Certifications
| 2019 | Certification Board of Cardiovascular Magnetic Resonance |
| 2013 | Certification Board of Nuclear Cardiology, Council for Certification in Cardiovascular Imaging |
| 2012 | Adult Comprehensive Echocardiography, American Board of Echocardiography |
| 2012 | Certification Board of Cardiovascular Computed Tomography, Council for Certification in Cardiovascular Imaging |
| 2011 | Cardiovascular Disease, American Board of Internal Medicine |
| 2008 | Internal Medicine, American Board of Internal Medicine |
Experience & Service
Academic Appointments
Assistant Professor, Department of Diagnostic Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2019
Assistant Professor, Department of Cardiology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2019
Honors & Awards
| 2018 | Super Doctors® Rising Stars 2018, Super Doctors® |
| 2018 | Elected Fellow, Society for Cardiovascular Magnetic Resonance |
| 2017 | Super Doctors® Rising Stars 2017, Super Doctors® |
| 2017 | Listed in Marquis Who'sWho in Medicine and Healthcare, Marquis Who'sWho® |
| 2017 | Elected Fellow, Society of Cardiovascular Computed Tomography |
| 2013 | Cardiovascular Imaging Section's Travel Award, American College of Cardiology Scientific Sessions |
| 2013 | Elected Fellow, American College of Cardiology |
| 2013 | Elected Fellow, American Society of Echocardiography |
| 2013 | Doximity Fellow, Doximity App |
| 2011 | Award for Excellence for Establishing the Fellows in Training Delegate Position, Puerto Rico American College of Cardiology |
| 2010 | Chief Fellow, Cardiology, San Juan V.A Medical Center |
| 2008 | Internal Medicine In-training Exam Highest Score Award, UPR School of Medicine Internal Medicine Training Program |
| 2005 | Clinical Distinction Award, Ponce School of Medicine |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Sarah A. Milgrom, Bibin Varghese, Gregory W. Gladish, Wenli Dong, Zarana Patel, Caroline C. Chung, Arvind Rao, Chelsea C. Pinnix, Jillian R. Gunther, Bouthaina S. Dabaja, Steven H. Lin, Karen E. Hoffman, Janice Huff, Jordan Slagowski, Jun-ichi Abe, Cezar A. Iliescu, Jose Banchs, S. Wamique Yusuf, Juan C. Lopez-Mattei. Coronary Artery Dose-Volume Parameters Predict the Risk of Calcification After Radiation Therapy. Journal of Cardiovascular Imaging, 2019.
- Zarifa A, Albittar A, Kim PY, Hassan S, Palaskas N, Iliescu C, Durand JB, Lopez-Mattei J. Cardiac Toxicities of Anticancer Treatments: Chemotherapy, Targeted Therapy and Immunotherapy. Curr Opin Cardiol 34(4):441-450, 2019. e-Pub 2019. PMID: 31082852.
- Balanescu SM, Balanescu DV, Donisan T, Yang EH, Palaskas N, Lopez-Mattei J, Hassan S, Kim P, Cilingiroglu M, Marmagkiolis K, Kar B, Iliescu C. The Onco-cardiologist Dilemma: to Implant, to Defer, or to Avoid Transcatheter Aortic Valve Replacement in Cancer Patients with Aortic Stenosis?. Curr Cardiol Rep 21(8):83, 2019. e-Pub 2019. PMID: 31286273.
- Balanescu DV, Donisan T, Lopez-Mattei J, Hassan S, Kim P, Dasari A, Halperin D, Yao J, Kar B, Gregoric I, Balanescu SM, Iliescu C. The 1, 2, 3, 4 of carcinoid heart disease: Comprehensive cardiovascular imaging is the mainstay of complex surgical treatment. Oncol Lett 17(5):4126-4132, 2019. e-Pub 2018. PMID: 30944605.
- Layoun ME, Yang EH, Herrmann J, Iliescu CA, Lopez-Mattei JC, Marmagkiolis K, Budoff MJ, Ferencik M. Applications of Cardiac Computed Tomography in the Cardio-Oncology Population. Curr Treat Options Oncol 20(6):47, 2019. e-Pub 2019. PMID: 31056717.
- Palaskas N, Morgan J, Daigle T, Banchs J, Durand JB, Hong D, Naing A, Le H, Hassan SA, Karimzad K, Mouhayar E, Kim P, Lopez-Mattei J, Thompson K, Yusuf SW, Iliescu C. Targeted Cancer Therapies with Pericardial Effusions Requiring Pericardiocentesis Focusing on Immune Checkpoint Inhibitors. Am J Cardiol 123(8):1351-1357, 2019. e-Pub 2019. PMID: 30765065.
- Parwani P, Choi AD, Lopez-Mattei J, Raza S, Chen T, Narang A, Michos ED, Erwin JP, Mamas MA, Gulati M. Understanding Social Media: Opportunities for Cardiovascular Medicine. J Am Coll Cardiol 73(9):1089-1093, 2019. PMID: 30846102.
- Balanescu DV, Monlezun DJ, Donisan T, Boone D, Cervoni-Curet F, Palaskas N, Lopez-Mattei J, Kim P, Iliescu C, Balanescu SM. A Cancer Paradox: Machine-Learning Backed Propensity-Score Analysis of Coronary Angiography Findings in Cardio-Oncology. J Invasive Cardiol 31(1):21-26, 2019. PMID: 30611123.
- Lopez-Mattei J, Kim P, Iliescu C. Editorial Commentary: Update on cardio-oncology: Novel cancer therapeutics and associated cardiotoxicities. Trends Cardiovasc Med 29(1):40, 2019. e-Pub 2018. PMID: 29958808.
- Agha AM, Lopez-Mattei J, Donisan T, Balanescu D, Iliescu CA, Banchs J, Kim PY, Palaskas NL, Yusuf S, Gladish G, Hassan S. Multimodality imaging in carcinoid heart disease. Open Heart 6(1):e001060, 2019. e-Pub 2019. PMID: 31245014.
- Parwani P, Lopez-Mattei J, Choi AD. Building Bridges in Cardiology and Radiology: Why Collaboration Is the Future of Cardiovascular Imaging. JACC Cardiovasc Imaging 11(11):1713-1717, 2018. PMID: 30409331.
- Parwani P, Lopez-Mattei J, Choi AD. Building Bridges in Cardiology and Radiology: Why Collaboration Is the Future of Cardiovascular Imaging. J Am Coll Cardiol 72(20):2534-2538, 2018. PMID: 30442296.
- Varghese B, Ting K, Lopez-Mattei J, Iliescu C, Kim J, Kim P. Aspergillus endocarditis of the mitral valve with ventricular myocardial invasion, cerebral vasculitis, and intracranial mycotic aneurysm formation in a patient with hemophagocytic lymphohistiocytosis. Med Mycol Case Rep 21:49-51, 2018. e-Pub 2018. PMID: 29755935.
- Donisan T, Balanescu DV, Lopez-Mattei JC, Kim P, Leja MJ, Banchs J, Marmagkiolis K, Herrmann J, Gregoric I, Durand JB, Iliescu CA. In Search of a Less Invasive Approach to Cardiac Tumor Diagnosis: Multimodality Imaging Assessment and Biopsy. JACC Cardiovasc Imaging 11(8):1191-1195, 2018. PMID: 30092973.
- Palaskas N, Thompson K, Gladish G, Agha AM, Hassan S, Iliescu C, Kim P, Durand JB, Lopez-Mattei JC. Evaluation and Management of Cardiac Tumors. Curr Treat Options Cardiovasc Med 20(4):29, 2018. e-Pub 2018. PMID: 29556752.
- Hassan SA, Palaskas N, Kim P, Iliescu C, Lopez-Mattei J, Mouhayar E, Mougdil R, Thompson K, Banchs J, Yusuf SW. Chemotherapeutic Agents and the Risk of Ischemia and Arterial Thrombosis. Curr Atheroscler Rep 20(2):10, 2018. e-Pub 2018. PMID: 29423705.
- Liu VY, Agha AM, Lopez-Mattei J, Palaskas N, Kim P, Thompson K, Mouhayar E, Marmagkiolis K, Hassan SA, Karimzad K, Iliescu CA. Interventional Cardio-oncology: Adding a New Dimension to the Cardio-oncology Field. Front Cardiovasc Med 5:48, 2018. e-Pub 2018. PMID: 29868614.
- Agha AM, Parwani P, Guha A, Durand JB, Iliescu CA, Hassan S, Palaskas NL, Gladish G, Kim PY, Lopez-Mattei J. Role of cardiovascular imaging for the diagnosis and prognosis of cardiac amyloidosis. Open Heart 5(2):e000881, 2018. e-Pub 2018. PMID: 30305910.
- Iliescu CA, Cilingiroglu M, Giza DE, Rosales O, Lebeau J, Guerrero-Mantilla I, Lopez-Mattei J, Song J, Silva G, Loyalka P, Paixao ARM, Yusuf SW, Perin E, Anderson VH, Marmagkiolis K. "Bringing on the light" in a complex clinical scenario: Optical coherence tomography-guided discontinuation of antiplatelet therapy in cancer patients with coronary artery disease (PROTECT-OCT registry). Am Heart J 194:83-91, 2017. e-Pub 2017. PMID: 29223438.
- Giza DE, Moudgil R, Lopez-Mattei J, Kim P, Iliescu C. Association between ibrutinib and mid-cavitary Takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced Takostubo's cardiomyopathy. Eur Heart J Case Rep 1(2):ytx006, 2017. e-Pub 2017. PMID: 31020065.
- Giza DE, Boccalandro F, Lopez-Mattei J, Iliescu G, Karimzad K, Kim P, Iliescu C. Ischemic Heart Disease: Special Considerations in Cardio-Oncology. Curr Treat Options Cardiovasc Med 19(5):37, 2017. PMID: 28425056.
- Lopez-Mattei JC. Path to Cardiovascular Multimodality Imaging Subspecialty. JACC Cardiovasc Imaging 10(1):97-98, 2017. PMID: 28057229.
- Hassan SA, Lopez-Mattei J, Sanchez L, Banchs J. Improved reliability in left ventricular ejection fraction assessment by adopting quantitative methods. Echocardiography 33(12):1936-1937, 2016. PMID: 27917602.
- Faiz SA, Iliescu C, Lopez-Mattei J, Patel B, Bashoura L, Popat U. Resolution of myelofibrosis-associated pulmonary arterial hypertension following allogeneic hematopoietic stem cell transplantation. Pulm Circ 6(4):611-613, 2016. PMID: 28090305.
- Munoz E, Iliescu G, Vejpongsa P, Charitakis K, Karimzad K, Lopez-Mattei J, Yusuf SW, Marmagkiolis K, Iliescu C. Takotsubo Stress Cardiomyopathy: "Good News" in Cancer Patients?. J Am Coll Cardiol 68(10):1143-4, 2016. PMID: 27585514.
- Lopez-Mattei JC, Ibrahim H, Shaikh KA, Little SH, Shah DJ, Maragiannis D, Zoghbi WA. Comparative Assessment of Mitral Regurgitation Severity by Transthoracic Echocardiography and Cardiac Magnetic Resonance Using an Integrative and Quantitative Approach. Am J Cardiol 117(2):264-70, 2016. e-Pub 2015. PMID: 26684513.
- Chaikriangkrai K, Lopez-Mattei JC, Lawrie G, Ibrahim H, Quinones MA, Zoghbi W, Little SH, Shah DJ. Prognostic Value of Delayed Enhancement Cardiac Magnetic Resonance Imaging in Mitral Valve Repair. Ann Thorac Surg 98(5):1557-63, 2014. e-Pub 2014. PMID: 25240782.
- Chaikriangkrai K, Lopez-Mattei JC, Flores-Arredondo J, Lin H, Reardon M, Chang SM, Shah D. Magnetic resonance imaging of a Scimitar vein and aortic dissection. Methodist Debakey Cardiovasc J 10(4):257, 2014. PMID: 25624983.
- Simprini LA, Afroz A, Cooper MA, Klem I, Jensen C, Kim RJ, Srichai MB, Heitner JF, Sood M, Chandy E, Shah DJ, Lopez-Mattei J, Biederman RW, Grizzard JD, Fuisz A, Ghafourian K, Farzaneh-Far A, Weinsaft J. Routine Cine-CMR for Prosthesis Associated Mitral Regurgitation - A Multicenter Comparison to Echocardiography. J Heart Valve Dis 23(5):575-582, 2014. e-Pub 2014. PMID: 25799706.
- Yusuf SW, Solhpour A, Banchs J, Lopez-Mattei JC, Durand JB, Iliescu C, Hassan SA, Qazilbash MH. Cardiac amyloidosis. Expert Rev Cardiovasc Ther 12(2):265-77, 2014. e-Pub 2014. PMID: 24386926.
- Lopez-Mattei JC, Shah DJ. When to consider cardiovascular magnetic resonance in patients undergoing transcatheter aortic valve replacement?. Curr Opin Cardiol 28(5):505-11, 2013. e-Pub 2013. PMID: 23852024.
- Lopez-Mattei JC, Shah DJ. The Role of Cardiac Magnetic Resonance in Valvular Heart Disease. Methodist Debakey Cardiovasc J 9(3):142-148, 2013. PMID: 24066197.
- Lopez-Mattei JC, Nabi F, Little SH, Shah D. Museum of TMH Multimodality Imaging Center: Left Ventricular Pseudoaneurysm. Methodist Debakey Cardiovasc J 9(2):114, 2013. PMID: 23805348.
- Figueroa Y, Altieri PI, Banchs H, Hernández J, López JC, Escobales N, Crespo MJ. Syncope in Puerto Rico. Bol Asoc Med P R 99(3):207-10, 2007. PMID: 19610576.
- Moudgil R, Hassan S, Palaskas N, Lopez-Mattei J, Banchs J, Yusuf SW. Evolution of Echocardiography in subclinical detection of Cancer Therapy related Cardiac Dysfunction. Echocardiography. e-Pub 2018. PMID: 29749652.
- Giza DE, Lopez-Mattei J, Vejpongsa P, Munoz E, Iliescu G, Kitkungvan D, Hassan SA, Kim P, Ewer MS, Iliescu C. Stress-Induced Cardiomyopathy in Cancer Patients. Am J Cardiol. e-Pub 2017. PMID: 29096885.
- Lopez-Mattei J, Iliescu C, Durand JB, Hassan S, Kim P, Sierra-Galan L, Gladish G. The role of cardiac MRI in cardio-oncology. Future Cardiol. e-Pub 2017. PMID: 28639454.
- Reddy N, Moudgil R, Lopez-Mattei JC, Karimzad K, Mouhayar EN, Somaiah N, Conley AP, Patel S, Giza DE, Iliescu C. Progressive and Reversible Conduction Disease with Checkpoint Inhibitors. Can J Cardiol. e-Pub 2017. PMID: 28822650.
- Hassan SA, Banchs J, Iliescu C, Dasari A, Lopez-Mattei J, Yusuf SW. Carcinoid heart disease. Heart. e-Pub 2017. PMID: 28596302.
- Bhatti S, Hendel RC, Lopez-Mattei J, Schwartz RG, Raff G, Einstein AJ. Frequent MUGA testing in a myeloma patient: A case-based ethics discussion. J Nucl Cardiol. e-Pub 2016. PMID: 27272150.
- Balanescu DV, Donisan T, Palaskas N, Lopez-Mattei J, Iliescu C. Halloween in the Cath Lab: spider web pericardial effusion. Eur Heart J Cardiovasc Imaging. e-Pub 2019. PMID: 31501856.
- Potts J, Mohamed MO, Lopez Mattei JC, Iliescu CA, Konopleva M, Rashid M, Bagur R, Mamas MA. Percutaneous coronary intervention and in-hospital outcomes in patients with leukemia: a nationwide analysis. Catheter Cardiovasc Interv. e-Pub 2019. PMID: 31410970.
- Borovac JA, Kwok CS, Iliescu C, Lee HJ, Kim PY, Palaskas NL, Zaman A, Butler R, Lopez-Mattei JC, Mamas MA. Percutaneous Coronary Intervention and Outcomes in Patients With Lymphoma in the United States (Nationwide Inpatient Sample [NIS] Analysis). Am J Cardiol. e-Pub 2019. PMID: 31395298.
- Guha A, Buck B, Biersmith M, Arora S, Yildiz V, Wei L, Awan F, Woyach J, Lopez-Mattei J, Plana-Gomez JC, Oliveira GH, Fradley MG, Addison D. Contemporary Impacts of a Cancer Diagnosis on Survival Following In-Hospital Cardiac Arrest. Resuscitation 142:30-37. e-Pub 2019. PMID: 31310845.
- Styskel BA, Lopez-Mattei J, Jimenez CA, Stewart J, Hagemeister FB, Faiz SA. Ibrutinib-Associated Serositis in Mantle Cell Lymphoma. Am J Respir Crit Care Med. e-Pub 2019. PMID: 30802411.
- Balanescu DV, Donisan T, Dayah T, Palaskas N, Lopez-Mattei J, Kim P, Pinnix CC, Moudgil R, Balanescu SM, Herrmann J, Cilingiroglu M, Marmagkiolis K, Iliescu C. Refractory radiation-induced coronary artery disease: mapping the path and guiding treatment with optical coherence tomography. Int J Cardiovasc Imaging. e-Pub 2019. PMID: 30758691.
- Ghotra AS, Thompson K, Lopez-Mattei J, Bawa D, Hernandez R, Banchs J, Palaskas N, Iliescu C, Kim P, Yusuf SW, Hassan SA. Cardiovascular manifestations of Erdheim-Chester disease. Echocardiography. e-Pub 2018. PMID: 30569522.
- Schechter M, Balanescu DV, Donisan T, Dayah TJ, Kar B, Gregoric I, Giza DE, Song J, Lopez-Mattei J, Kim P, Balanescu SM, Cilingiroglu M, Toutouzas K, Smalling RW, Marmagkiolis K, Iliescu C. An update on the management and outcomes of cancer patients with severe aortic stenosis. Catheter Cardiovasc Interv. e-Pub 2018. PMID: 30549397.
- Sudasena D, Balanescu DV, Donisan T, Hassan S, Palaskas N, Kim P, Karimzad K, Lopez-Mattei J, Arain S, Gould KL, Iliescu C. Fulminant Vascular and Cardiac Toxicity Associated with Tyrosine Kinase Inhibitor Sorafenib. Cardiovasc Toxicol. e-Pub 2018. PMID: 30543051.
- Potts JE, Iliescu CA, Lopez Mattei JC, Martinez SC, Holmvang L, Ludman P, De Belder MA, Kwok CS, Rashid M, Fischman DL, Mamas MA. Percutaneous coronary intervention in cancer patients: a report of the prevalence and outcomes in the United States. Eur Heart J. e-Pub 2018. PMID: 30500952.
- Iliescu C, Balanescu DV, Donisan T, Giza DE, Muñoz Gonzalez ED, Cilingiroglu M, Song J, Mukerji SS, Lopez-Mattei JC, Kim PY, Palaskas N, Mouhayar EN, Durand JB, Marmagkiolis K. Safety of Diagnostic and Therapeutic Cardiac Catheterization in Cancer Patients with Acute Coronary Syndrome and Chronic Thrombocytopenia. Am J Cardiol. e-Pub 2018. PMID: 30180958.
- Zarifa A, Hadi M, Lopez-Mattei J, Lee HJ, Iliescu C, Hassan S, Palaskas N, Durand JB, Mouhayar E, Kim J, Kim P. Cardiotoxicity of immune-checkpoint inhibitors: A rare but serious adverse event. Journal of Immunotherapy and Precision Oncology. e-Pub 2018.
Book Chapters
- Lopez-Mattei, J. Evaluation of a Cardiac Mass. In: MD Anderson Practices in Onco-Cardiology. Department of Cardiology, MD Anderson Cancer Center: Houston, TX, 29,30, 2016.
- Juan C. López-Mattei, Miguel Quiñones. Evaluación de prótesis cardíacas. In: ECOCARDIOGRAFÍA E IMAGEN CARDIOVASCULAR EN LA PRÁCTICA CLÍNICA. 1st. Distribuna Editorial: SIAC, 2014.