Junmei Wang, PhD
Department of Melanoma Medical Oncology, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Instructor, Department of Melanoma Medical Oncology - Research, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2010 | Columbia University, New York, NY, USA, PHD, Immunology |
| 2002 | Beijing University, Beijing, CHN, MS, Pathology |
| 1999 | Beijing Medical University, Beijing, CHN, BM, Experimental Medicine |
Postgraduate Training
| 2010-2016 | Research Fellowship, UT MD Anderson Cancer Center, Houston, TX |
Selected Publications
Peer-Reviewed Articles
- Park J, Talukder AH, Lim SA, Kim K, Pan K, Melendez B, Bradley SD, Jackson KR, Khalili JS, Wang J, Creasy C, Pan BF, Woodman SE, Bernatchez C, Hawke D, Hwu P, Lee KM, Roszik J, Lizée G, Yee C. SLC45A2: A Melanoma Antigen with High Tumor Selectivity and Reduced Potential for Autoimmune Toxicity. Cancer Immunol Res 5(8):618-629, 2017. e-Pub 2017. PMID: 28630054.
- Haymaker C, Yang Y, Wang J, Zou Q, Sahoo A, Alekseev A, Singh D, Ritthipichai K, Hailemichael Y, Hoang ON, Qin H, Schluns KS, Wang T, Overwijk WW, Sun SC, Bernatchez C, Kwak LW, Neelapu SS, Nurieva R. Absence of Grail promotes CD8+ T cell anti-tumour activity. Nat Commun 8(1):239, 2017. e-Pub 2017. PMID: 28798332.
- Wang X, Wang J, Zheng H, Xie M, Hopewell EL, Albrecht RA, Nogusa S, García-Sastre A, Balachandran S, Beg AA. Differential requirement for the IKKβ/NF-κB signaling module in regulating TLR- versus RLR-induced type 1 IFN expression in dendritic cells. J Immunol 193(5):2538-45, 2014. e-Pub 2014. PMID: 25057006.
- Nurieva R, Wang J, Sahoo A. T-cell tolerance in cancer. Immunotherapy 5(5):513-531, 2013. PMID: 23638746.
- Nurieva RI, Podd A, Chen Y, Alekseev AM, Yu M, Qi X, Huang H, Wen R, Wang J, Li HS, Watowich SS, Qi H, Dong C, Wang D. STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J Biol Chem 287(14):11234-9, 2012. e-Pub 2012. PMID: 22318729.
- Ruan Q, Kameswaran V, Zhang Y, Zheng S, Sun J, Wang J, DeVirgiliis J, Liou HC, Beg AA, Chen YH. The Th17 immune response is controlled by the Rel-RORγ-RORγ T transcriptional axis. J Exp Med 208(11):2321-33, 2011. e-Pub 2011. PMID: 22006976.
- Basagoudanavar SH, Thapa RJ, Nogusa S, Wang J, Beg AA, Balachandran S. Distinct roles for the NF-kappa B RelA subunit during antiviral innate immune responses. J Virol 85(6):2599-610, 2011. e-Pub 2011. PMID: 21209118.
- Wang J, Basagoudanavar SH, Wang X, Hopewell E, Albrecht R, García-Sastre A, Balachandran S, Beg AA. NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication. J Immunol 185(3):1720-9, 2010. e-Pub 2010. PMID: 20610653.
- Vang KB, Yang J, Pagán AJ, Li LX, Wang J, Green JM, Beg AA, Farrar MA. Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. J Immunol 184(8):4074-7, 2010. e-Pub 2010. PMID: 20228198.
- Valenzuela JO, Iclozan C, Hossain MS, Prlic M, Hopewell E, Bronk CC, Wang J, Celis E, Engelman RW, Blazar BR, Bevan MJ, Waller EK, Yu XZ, Beg AA. PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice. J Clin Invest 119(12):3774-86, 2009. e-Pub 2009. PMID: 19907075.
- Wang J, Wang X, Hussain S, Zheng Y, Sanjabi S, Ouaaz F, Beg AA. Distinct roles of different NF-kappa B subunits in regulating inflammatory and T cell stimulatory gene expression in dendritic cells. J Immunol 178(11):6777-88, 2007. PMID: 17513725.
- Huang M, Zhang B, Wang J, Mei F, Hou L. Development of single-domain recombinant antibodies to reverse transcriptase domain of human hTERT. Hybrid Hybridomics 23(4):244-9, 2004. PMID: 15319072.
- Wang J, Zhang B, Yang S, He X, Han J, Li B, Hou L. Development of a monoclonal antibody for neutralization of human telomerase activity. Hybrid Hybridomics 21(4):295-300, 2002. PMID: 12193283.
- Zhang H, Zhang B, Wang J, Liu C, Han J, Yang S, Hou L. Single domain antibody to human telomerase catalytic subunit: preparation and characterization. Zhonghua Bing Li Xue Za Zhi 31(2):143-7, 2002. PMID: 12419163.
- Yang S, Zhang B, Wang J, Liao S, Han J, Wei J, Hou L. [Monoclonal antibodies against human telomerase reverse transcriptase: preparation, characterization, and application]. Zhonghua Bing Li Xue Za Zhi 31(1):50-4, 2002. PMID: 11955337.
- Yang S, Zhang B, Wang J, Liao S, Han J, Wei J, Hou L. Monoclonal antibodies against human telomerase reverse transcriptase (hTERT): preparation, characterization, and application. Hybridoma 20(4):249-55, 2001. PMID: 11604111.