Miguel A. Rodriguez-Bigas, MD, FACS, FASCRS

Peer-Reviewed Articles

1. Jasperson KW, Vu TM, Schwab AL, Neklason DW, Rodriguez-Bigas MA, Burt RW, Weitzel JN Evaluating Lynch syndrome in very early onset colorectal cancer probands without apparent polyposis. Fam Cancer 9 (2) :99-107, 2010. e-Pub 2009. PMID: 19731080
2. De Jesus-Monge WE, Gonzalez-Keelan C, Zhao R, Hamilton SR, Rodriguez-Bigas M, Cruz-Correa M Mismatch repair protein expression and colorectal cancer in Hispanics from Puerto Rico. Fam Cancer 9 (2) :155-166, 2010. e-Pub 2009. PMID: 20012372
3. Callender GG, Das P, Rodriguez-Bigas MA, Skibber JM, Crane CH, Krishnan S, Delclos ME, Feig BW Local excision after preoperative chemoradiation results in an equivalent outcome to total mesorectal excision in selected patients with T3 rectal cancer. Ann Surg Oncol 17 (2) :441-7, 2010. PMID: 19847569
4. Smith KD, Tan D, Das P, Chang GJ, Kattepogu K, Feig BW, Skibber JM, Rodriguez-Bigas MA Clinical significance of acellular mucin in rectal adenocarcinoma patients with a pathologic complete response to preoperative chemoradiation. Ann Surg 251 (2) :261-4, 2010. PMID: 19864936
5. Brouquet A, Mortenson MM, Vauthey JN, Rodriguez-Bigas MA, Overman MJ, Chang GJ, Kopetz S, Garrett C, Curley SA, Abdalla EK Surgical strategies for synchronous colorectal liver metastases in 156 consecutive patients: classic, combined or reverse strategy? J Am Coll Surg 210 (6) :934-41, 2010. PMID: 20510802
6. Silberfein EJ, Kattepogu KM, Hu CY, Skibber JM, Rodriguez-Bigas MA, Feig B, Das P, Krishnan S, Crane C, Kopetz S, Eng C, Chang GJ Long-term survival and recurrence outcomes following surgery for distal rectal cancer. Ann Surg Oncol 17 (11) :2863-9, 2010. PMID: 20552409
7. You YN, Habiba H, Chang GJ, Rodriguez-Bigas MA, Skibber JM Prognostic Value of Quality of Life and Pain in Patients with Locally Recurrent Rectal Cancer. Ann Surg Oncol. PMID: 21132391
8. Das P, Delclos ME, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Eng C, Bedi M, Krishnan S, Crane CH Hyperfractionated Accelerated Radiotherapy for Rectal Cancer in Patients with Prior Pelvic Irradiation. Int J Radiat Oncol Biol Phys 77 (1) :60-5. PMID: 19695792
9. Crane CH, Eng C, Feig BW, Das P, Skibber JM, Chang GJ, Wolff RA, Krishnan S, Hamilton S, Janjan NA, Maru DM, Ellis LM, Rodriguez-Bigas MA Phase II Trial of Neoadjuvant Bevacizumab, Capecitabine, and Radiotherapy for Locally Advanced Rectal Cancer. Int J Radiat Oncol Biol Phys 76 (3) :824-30. PMID: 19464823
10. Carmack CL, Basen-Engquist K, Yuan Y, Greisinger A, Rodriguez-Bigas M, Wolff RA, Barker T, Baum G, Pennebaker JW Feasibility of an expressive-disclosure group intervention for post-treatment colorectal cancer patients: Results of the healthy expressions study. Cancer 117 (21) :4993-5002. PMID: 21480203
11. Tsai CJ, Crane CH, Skibber JM, Rodriguez-Bigas MA, Chang GJ, Feig BW, Eng C, Krishnan S, Maru DM, Das P Number of lymph nodes examined and prognosis among pathologically lymph node-negative patients after preoperative chemoradiation therapy for rectal adenocarcinoma. Cancer 117 (16) :3713-22. PMID: 21328329

Invited Articles

1. Rodriguez-Bigas MA, Chang GJ, Skibber JM, Multidisciplinary approach to recurrent/unresectable rectal cancer: how to prepare for the extent of resection., 19 (4) :847-59, 2010

Abstracts

1. You YN, Vilar E, Cuddy A, Wu A, Lynch PM, Eng C, Rodriguez-Bigas MA, Chang GJ Are young adults with colorectal cancer doing enough to stay healthy? AACR Annual Meeting 2015, 2015
2. Morris VK, Rashis A, Rodriguez-Bigas MA, Das P, Wolff RA, Chang GJ, Crane CH, Phillips J, Ohinata A, Roger J, Eng C Human papillomavirus is associated with unique clinicopathologic features in patients with metastatic squamous cell carcinoma of the anal canal. 2014 Gastrointestinal Cancers Symposium, 2014
3. Bailey CE, Rodriguez-Bigas MA, Tran Cao HA, Chang GJ, Feig B, Nguyen S, Skibber JM, You N Persistent Functional Deficits and Symptoms among Long-Term Survivors of Colorectal Cancer Treated with Surgery and Multimodality Therapy: Differences by Age at Initial Diagnosis Digestive Disease Week 2014, 2014
4. Burton-Chase AM, Parker WM, Polivka KM, Gritz ER, Amos CI, Frazier ML, Lu KH, Lynch PM, Rodriguez-Bigas MA, You YN, Peterson SK Provider satisfaction in colorectal cancer patients: A comparison between Lynch syndrome and sporadic survivors CGA-ICC 18th Annual Meeting, 2014
5. You YN, Chang GJ, Cormier J, Fieg BW, Rodriguez-Bigas M, Skibber JM A Framework For Developing Quality Measures Of Survivorship Care In Colorectal Cancer 2013 Cancer Survivorship Research Retreat, 2013
6. You YN, Chang GJ, Feig BW, Skibber JM, Rodriguez-Bigas MA DNA Mismatch Repair Defects Do Not Account for the Majority of Newly Diagnosed Young-Onset Colorectal Cancers. 2013 ASCRS Annual Meeting, 2013
7. Sanchez EV, Wu W, Bhatia G, Cuddy A, Mork MM, Bannon SA, Lynch PM, Rodriguez-Bigas MA, Taggart MW, You YN Can microsatellite status of colorectal cancer (CRC) be reliably assessed after neoadjuvant therapy? 2013 ASCO Annual Meeting, 2013
8. You YN, Sanchez EV, Slack R, Chang GJ, Nguyen ST, Cuddy A, Khose S, Wisniewski W, Bannon S, Mork MM, Lynch PM, Rodriguez-Bigas M Lynch syndrome testing in ethnically diverse patients: Mutation spectrum and performance of prediction models 2013 ASCO Annual Meeting, 2013
9. Ernst R, Kaur H, Chang G, You YN, Rodriguez-Bigas M Unraveling Colorectal Conference Conundrums using MRI RSNA 2013, 2013
10. You NY, Bednarski B, Chang GJ, Khose S, Nguyen S, Feig B, Skibber J, Rodriguez-Bigas M DNA Mismatch Repair Defects do not Account for the Majority of Newly Diagnosed Young-onset Colorectal Cancers 2013 ASCRS Annual Meeting, 2013
11. Hyngstrom JR, Rodriguez-Bigas MA, Chang GJ, Taggart MW, Skibber JM, Feig BW, You YN Microsatellite high colorectal cancer: Does the underlying mechanism for instability matter? 2012 Gastrointestinal Cancers Symposium, 2012
12. Das P, Eng C, Rodriguez-Bigas MA, Chang GJ, Skibber JM, Maru D, Munsell MF, Celmons MV, Kopetz S, Garrett CR, Shureiqi I, Krishnan S, Delclos ME, Crane CH Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal adenocarcinoma: A phase I trial. 2012 Gastrointestinal Cancers Symposium, 2012
13. Russell, M, Chiang Y, Feig BW, Chang GJ, Rodriguez-Bigas MA, Skibber JM, Chagpar R, Cormier JN, You YN Lymph node metastasis in patients with early pathologic T-stage rectal cancers: What does local excision leave behind? 2012 Gastrointestinal Cancers Symposium, 2012
14. Chang GJ, Hu CY, You YN, Eng C, Rodriguez-Bigas MA, Skibber JM What determines adjuvant chemotherapy use after neoadjuvant chemoradiotherapy for rectal cancer? 2012 Gastrointestinal Cancers Symposium, 2012
15. Mitchell MP, Abboud M, Crane CH, Eng C, Chang GJ, Rodriguez-Bigas MA, Skibber JM, You YN, Beddar S, Krishnan S, Delclos ME, Das P Intensity-modulated radiation therapy (IMRT) with concurrent chemotherapy for anal cancer: A large single-institution experience. 2012 Gastrointestinal Cancers Symposium, 2012
16. Tzeng CD, Chang GJ, Curley SA, Vauthey JN, Ellis LM, Skibber JM, Feig BW, Abdalla EK, Aloia TA, You YN, Rodriguez-Bigas MA, Morbidity of staged proctectomy after hepatectomy for colorectal cancer: A matched case-control analysis. 2012 Gastrointestinal Cancers Symposium, 2012
17. Park IJ, Eng C, You YN, Kopetz S, Rodriguez-Bigas MA, Overman MJ, Skibber JM, Chang GJ Exploratory analysis of adjuvant chemotherapy effects after preoperative chemoradiotherapy and radical resection for rectal cancer. 2012 Gastrointestinal Cancers Symposium, 2012
18. Russell MC, Rodriguez-Bigas MA, Chang GJ, Skibber JM, Feig BW, You YN Detection of hereditary nonpolyposis colorectal cancer (HNPCC) in non-Caucasian patients. 2012 Gastrointestinal Cancers Symposium, 2012
19. Abbott DE, Cantor SB, Rodriguez-Bigas MA, Chang GJ, Lynch PM, Feig BW, Skibber JM, You YN Detecting hereditary nonpolyposis colorectal cancer syndrome (HNPCC) in patients with colorectal cancer (CRC): Optimal strategies at lower costs. 2012 Gastrointestinal Cancers Symposium, 2012
20. Eng C, Rogrs J, Chang GJ, You YN, Das P, Rodriguez-Bigas MA, Ohinata A, Phillips J, Abbruzzese JL, Wolff RA Choice of chemotherapy in the treatment of metastatic squamous cell carcinoma of the anal canal. 2012 ASCO Annual Meeting, 2012
21. Chang GJ, Park IJ, Eng C, You YN, Kopetz S, Overman MJ, Rodriguez-Bigas MA, Skibber JM Exploratory analysis of adjuvant chemotherapy benefits after preoperative chemoradiotherapy and radical resection for rectal cancer. 2012 ASCO Annual Meeting, 2012
22. Tzeng CD, Chang GJ, Curley SA, Vauthey JN, Ellis LM, Skibber JM, Feig BW, Abdalla EK, Aloia TA, You YN, Rodriguez-Bigas MA Morbidity of Staged Proctectomy after Hepatectomy for Colorectal Cancer: A Matched Case-control Analysis Society of Surgical Oncology, 65th Annual Cancer Syposium, 2012
23. Hyngstrom JR, Rodriguez-Bigas MA, Chang GJ, Taggart MW, Skibber JM, Feig BW, You YN, Microsatellite High Colorectal Cancer: Does the Underlying Mechanism for Instability Matter? Society of Surgical Oncology, 65th Cancer Symposium, 2012
24. Russell MC, Rodriguez-Bigas MA, Chang GJ, Skibber JM, Feig BW, You YN Hereditary Nonpolyposis Colrectal Cancer in NonCaucasian Patients Society of Surgical, 2012
25. Russell MC, Chian Y, Feig BW, Chang GJ, Rodriguez-Bigas MA, Skibber JM, Chagpar R, Cormier JN, You YN Lymph Node Metastasis in Pateints with Early Pathologi T Stage Rectal Cancers: What Does Local Excision Leave Behind? Society of Surgical Oncology, 65th Annual Cancer Symposium, 2012
26. You YN, Xing B, Feig BW, Rodriguez-Bigas MA, Skibber JM, Chang GJ, Cormier JN Advanced-stage colon cancer prior to the screening age: Association with age, race, and insurance status 2011 Gastrointestinal Cancers Symposium, 2011
27. Eng C, Xing Y, You YN, Chang GJ, Das P, Phillips J, Wolff RA, Rodriguez-Bigas MA, Ohinata A, Crane CH Cisplatin (C) based chemoradiation (CXRT) for locally advanced squamous cell carcinoma (SCCA) of the anal canal (AC): A 20-year perspective 2011 Gastrointestinal Cancers Symposium, 2011
28. Chagpar A, Cormier JN, Feig BW, Chang GJ, You YN, Rodriguez-Bigas MA, Skibber AM, Xing Y Adherence to NCCN treatment guidelines for rectal cancer: Analysis of national practice patterns 2011 ASCO Annual Meeting, 2011
29. Chang GJ, Park IJ, You YN, Hu C, Hamilton SR, Eng C, Feig BW, Das P, Krishnan S, Crane CH, Nguyen ST, Rodriguez-Bigas MA, Skibber JM Neoadjuvant treatment response and outcomes in locally advanced rectal cancer: Establishing oncologic benchmarks 2011 ASCO Annual Meeting, 2011
30. Park IJ, Hu C, Rodriguez-Bigas MA, You YN, Skibber JM, Eng C, Wolff RA, Das P, Crane CH, Chang GJ Oncologic and functional hazards of obesity among patients with locally advanced rectal cancer 2011 ASCO Annual Meeting, 2011
31. Patel CB, Kattepogu KM, Park IJ, Eng C, Delclos ME, Feig BW, Crane CH, Skibber JM, Das P, Rodriguez-Bigas MA, Krishnan S, Chang GJ Impact of preoperative radiation dose escalation on pathologic outcomes and radiation toxicity in locally advanced rectal cancer (LARC): A matched-pair analysis 2011 ASCO Annual Meeting, 2011
32. Abbott DE, Thomas AA, Rodriguez-Bigas MA, Skibber JM, Feig BW, You YN, Curley SA, Vauthey JN, Chang GJ Economic Comparison of Simultaneous and Staged Resection for Synchronous Metastatic Colorectal Cancer 97th Annual American College of Surgeons Clinical Congress, 2011
33. You YN, Halim H, Chang GJ, Rodriguez-Bigas MA Prognostic value of pain and quality of life in patients with locally recurrent rectal cancer Proc SSO, 2010
34. You YN, Saraiya D, Vu TM, Veerapong J, Lynch PM, Rodriguez-Bigas MA Rectal cancer in patients with hereditary nonpolyposis colorectal cancer: surgical management and survival outcomes 14th Annual Meeting of the Collaborative Group of the Americas on Colorectal Cancer, 2010
35. Ernst RD, Kaur H, You YN, Chang GJ, Rodriguez-Bigas MA Structured reporting for MRI staging of rectal cancer 96th Scientific Assembly and Annual Meeting of the Radiological Society of North America, 2010
36. Saraiya D, You YN, Askew RL, Vu TM, Lynch PM, Rodriguez-Bigas MA The importance of tumor studies in the initial evaluation for Lynch Syndrome: a coparison of MMR postive and negative patients 14th Annual Meeting of the Collaborative Group of the Americas on Inherited Colorectal Cancer, 2010
37. Bowles TL, Hu C, Skibber JM, Rodriguez-Bigas MA, Chang GJ Cancers of the colon and rectum Proc ASCO GI, 2010
38. You YN, Choi EA, Skibber JM, Rodriguez-Bigas MA, Feig BW, Eng C, Crane CH, Das P, Chang GJ Multimodal salvage therapy for locally recurrent and re-recurrent rectal cancer Proc ASCO, 2010
39. Chang G, Maru D, Afarwal A, Schlette E, Wolff R, Rodriguez-Bigas MA, You YN, Feig B, Kopetz S, Skibber J, Eng C Histopathologic responses in primary tumors of patients with metastatic colorectal carcinoma after neoadjuvant systemic chemotherapy alone ESMO Conference: 12th World Congress on Gastrointestinal Cancer, 2010
40. Tsa CJ, Crane CH, Skibber JM, Rodriguez-Bigas MA, Chang GJ, Feig BF, Eng C, Delclos M, Krishnan S, Das P Number of lymph nodes retrieved and prognosis among pathologically node-negative patients after preoperative chemoradiation therapy for rectal cancer Proc ASCO, 2010
41. Tanaka M, Bedrosian I, Chang GJ, You NY, Li D, Rodriguez-Bigas MA, Skibber JM, Abbruzzese JL, Eng C Single nucleotide polymorphisms (SNPs) of hypoxia-related genes correlate with pathological complete response following neoadjuvant chemotherapy for locally advanced rectal cancer Proc ASCO, 2010
42. Eng C, Sethi S, Chang G, Rodriguez-Bigas M, Skibber J, Shen J, Zhu J, Ohinata A, Hamilton S, Li D Proteomic analysis of potential tumor markers in AJCC stage II and III colon cancer Proc ASCO, 2009
43. Behm KT, Mathis KL, Shariq O, Bikhchandani J, Lynch H, Rodriguez-Bigas MA, Cuddy A, Dozois EJ, You Y A Multi-institutional Study of Long-term Patient-reported Outcomes after Proctectomy vs. Proctocolectomy for Rectal Cancer in Patients with Lynch Syndrome ASCRS 2016 Annual Scientific Meeting, Los Angeles, CA, April 30-May 4, 2016

Book Chapters

1. Orr WS, Pisters LL, Rodriguez-Bigas MA, Intraoperative Ureteral Injury, In: Gastrointestinal Surgery: Management of Complex Perioperative Complications, Springer: New York, 361-70, 2015
2. Bannon S, Mork M, Rodriguez-Bigas MA, The young patient with colorectal cancer-genetic counseling discussion, In: Colorectal Cancer: Diagnosis and Management, Wiley Blackwell, 275-285, 2014
3. Rodriguez-Bigas MA, Tratamiento de las metástasis hepáticas sincrónicas, In: Enfoque Multidisciplinario del Cáncer Colorectal, Ediciones Journal S.A.: Argentina, 163-170, 2014
4. Roses RE, Rodriguez-Bigas MA, The Management of Rectal Cancer, In: Current Surgical Therapy, 11th, Elsevier Sanders: Philadelphia, PA, 218-224, 2013
5. Tan CH, Das P, Silberfein EJ, Rodriguez-Bigas MA, Iyer RB, Colorectal Cancer, In: Oncologic Imaging: A Multidisciplinary Approach, 2nd: Philadelphia, PA, 267-286, 2012
6. Bhadkamkar N, Crane CH, Rodriguez-Bigas MA, Kopetz S, Eng C, Colorectal Cancer, In: The MD Anderson Manual of Medical Oncology, 2nd, McGraw-Hill: New York, 549-588, 2011
7. Rodriguez-Bigas, MA, Polipose associada ao MYH (PAM), In: Polipose Adenomatosa Familiar, Yendis: Sao Paulo, Brazil, 2010
8. Alberts AR, Citrin D, Rodriguez-Bigas MA, Das P, Colon, Rectal, and anal cancers, In: Cancer Management: A Multidisciplinary Approach, CMP Media, 2010
9. Rodriguez-Bigas MA, Genotype phenotype correlation in familial adenomatous polyposis, In: Hereditary Colorectal Cancer, Springer: New York, 197-202, 2010
10. Cutait R, Rodriguez-Bigas MA, Surgical management in Lynch Syndrome, In: Hereditary Colorectal Cancer, Springer: New York, 301-310, 2010