Naveen Sharma, PhD
Department of Immunology, Division of Basic Sciences
About Dr. Naveen Sharma
I am driven by the desire to understand how the immune system works, and I am motivated to use this knowledge to enhance treatment efficacy against cancer. I have extensive experience in immunology, with training and expertise focused on cellular immunology, tumor immunology, in-vivo murine models, infectious diseases, immunological memory, co-stimulatory/co-inhibitory receptors (Checkpoint blockade), T cell differentiation, and Toll-like receptors (TLR). I am a motivated and highly skilled scientist with more than ten years of experience in immunology research with proficiency in project designing, data analysis, data interpretation. I am an Immunologist with knowledge of bioinformatics tools and expertise in various data analysis software. Professional with good communication, presentation and writing skills and well versed about literature.
Present Title & Affiliation
Primary Appointment
Instructor, Department of Immunology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX
Selected Publications
Peer-Reviewed Articles
- Sharma N, Vacher J, Allison JP. TLR1/2 ligand enhances anti-tumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion. Proc Natl Acad Sci U S A 116(21):10453-10462, 2019. e-Pub 2019. PMID: 31076558.
- Sharma N. Toll-like receptor activation – specific sensitization of cells to respond to host lipid(s) amplifies inflammatory responses, 2019.
- Sharma N, Allison JP. Ig-Like Receptor LILRB4 Regulates Anti-Tumor Immunity And is a Potential Target for Tumor Immunotherapy, 2019.
- Sharma N, Benechet AP, Lefrançois L, Khanna KM. CD8 T Cells Enter the Splenic T Cell Zones Independently of CCR7, but the Subsequent Expansion and Trafficking Patterns of Effector T Cells after Infection Are Dysregulated in the Absence of CCR7 Migratory Cues. J Immunol 195(11):5227-36, 2015. e-Pub 2015. PMID: 26500349.
- Sharma N, Akhade AS, Qadri A. Sphingosine-1-phosphate suppresses TLR-induced CXCL8 secretion from human T cells. J Leukoc Biol 93(4):521-8, 2013. e-Pub 2013. PMID: 23345392.