Shenying Fang, MD, PhD
Department of Surgical Oncology, Division of Surgery
About Dr. Shenying Fang
Dr. Fang is a biostatistician with a major interest in genetic diseases. He has applied novel statistical models to identify genetic and environmental determinants and image features for susceptibility to melanoma, treatment response and disease progression. Dr. Fang identified novel loci for familial lung cancer using an innovative approach that allows for etiological heterogeneity. He evaluated the modifying impact of P53 polymorphism on age to onset of cancer among carriers of P53 germline mutation. He also performs integrative analysis of DNA methylation, RNA expression and somatic mutation with medical image features to improve cancer diagnosis, to characterize tumor classification, and to predict individualized treatment effect and disease progression. His long term goal is to identify tumor-associated biomarkers in melanoma susceptibility, individualized treatment effect and progression and applying these biomarkers to clinical practice.
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Present Title & Affiliation
Primary Appointment
Associate Professor, Department of Surgical Oncology - Research, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2008 | The University of Texas School of Public Health, Houston, TX, USA, PHD, Biostatistics |
| 1999 | The Fourth Military Medical University, Xi'an, CHN, MS, Epidemiology |
| 1994 | Tongji Medical College of Huazhong University of Science and Technology, Wuhan, CHN, MD, Preventive Medicine |
Postgraduate Training
| 2009-2011 | Postdoc, Statistical Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- McQuade JL, Daniel CR, Hess KR, Mak C, Wang DY, Rai RR, Park JJ, Haydu LE, Spencer C, Wongchenko M, Lane S, Lee DY, Kaper M, McKean M, Beckermann KE, Rubinstein SM, Rooney I, Musib L, Budha N, Hsu J, Nowicki TS, Avila A, Haas T, Puligandla M, Lee S, Fang S, Wargo JA, Gershenwald JE, Lee JE, Hwu P, Chapman PB, Sosman JA, Schadendorf D, Grob JJ, Flaherty KT, Walker D, Yan Y, McKenna E, Legos JJ, Carlino MS, Ribas A, Kirkwood JM, Long GV, Johnson DB, Menzies AM, Davies MA. Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis. Lancet Oncol 19(3):310-322, 2018. e-Pub 2018. PMID: 29449192.
- Fang S, Wang Y, Dang Y, Gagel A, Ross MI, Gershenwald JE, Cormier JN, Wargo J, Haydu LE, Davies MA, McQuade JL, Sui D, Bassett RL, Reveille JD, Wei Q, Amos CI, Lee JE. Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes. J Invest Dermatol 137(8):1792-1795, 2017. e-Pub 2017. PMID: 28442307.
- Telomeres Mendelian Randomization Collaboration, Haycock PC, Burgess S, Nounu A, Zheng J, Okoli GN, Bowden J, Wade KH, Timpson NJ, Evans DM, Willeit P, Aviv A, Gaunt TR, Hemani G, Mangino M, Ellis HP, Kurian KM, Pooley KA, Eeles RA, Lee JE, Fang S, Chen WV, Law MH, Bowdler LM, Iles MM, Yang Q, Worrall BB, Markus HS, Hung RJ, Amos CI, Spurdle AB, Thompson DJ, O'Mara TA, Wolpin B, Amundadottir L, Stolzenberg-Solomon R, Trichopoulou A, Onland-Moret NC, Lund E, Duell EJ, Canzian F, Severi G, Overvad K, Gunter MJ, Tumino R, Svenson U, van Rij A, Baas AF, Bown MJ, Samani NJ, van t'Hof FNG, Tromp G, Jones GT, Kuivaniemi H, Elmore JR, Johansson M, Mckay J, Scelo G, Carreras-Torres R, Gaborieau V, Brennan P, Bracci PM, Neale RE, Olson SH, Gallinger S, Li D, Petersen GM, Risch HA, Klein AP, Han J, Abnet CC, Freedman ND, Taylor PR, Maris JM, Aben KK, Kiemeney LA, Vermeulen SH, Wiencke JK, Walsh KM, Wrensch M, Rice T, Turnbull C, Litchfield K, Paternoster L, Standl M, Abecasis GR, SanGiovanni JP, Li Y, Mijatovic V, Sapkota Y, Low SK, Zondervan KT, Montgomery GW, Nyholt DR, van Heel DA, Hunt K, Arking DE, Ashar FN, Sotoodehnia N, Woo D, Rosand J, Comeau ME, Brown WM, Silverman EK, Hokanson JE, Cho MH, Hui J, Ferreira MA, Thompson PJ, Morrison AC, Felix JF, Smith NL, Christiano AM, Petukhova L, Betz RC, Fan X, Zhang X, Zhu C, Langefeld CD, Thompson SD, Wang F, Lin X, Schwartz DA, Fingerlin T, Rotter JI, Cotch MF, Jensen RA, Munz M, Dommisch H, Schaefer AS, Han F, Ollila HM, Hillary RP, Albagha O, Ralston SH, Zeng C, Zheng W, Shu XO, Reis A, Uebe S, Hüffmeier U, Kawamura Y, Otowa T, Sasaki T, Hibberd ML, Davila S, Xie G, Siminovitch K, Bei JX, Zeng YX, Försti A, Chen B, Landi S, Franke A, Fischer A, Ellinghaus D, Flores C, Noth I, Ma SF, Foo JN, Liu J, Kim JW, Cox DG, Delattre O, Mirabeau O, Skibola CF, Tang CS, Garcia-Barcelo M, Chang KP, Su WH, Chang YS, Martin NG, Gordon S, Wade TD, Lee C, Kubo M, Cha PC, Nakamura Y, Levy D, Kimura M, Hwang SJ, Hunt S, Spector T, Soranzo N, Man. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. JAMA Oncol 3(5):636-651, 2017. PMID: 28241208.
- Fang S, Vaysse A, Brossard M, Wang Y, Deng D, Liu Q, Zhang P, Xu K, Li M, Feng R, Liu H, Dang Y, Chen W, Prieto V, Gershenwald JE, Ross MI, Matejka B, Malke J, Haydu LE, Reveille JD, Sui D, Bassett RL, Koshkina N, Avril MF, Lu M, Wei Q, Demenais F, Amos CI, Lee JE. Melanoma expression genes identified through genome-wide association study of Breslow tumor thickness. J Invest Dermatol 137(1):253-257, 2017. e-Pub 2016. PMID: 27506587.
- Karami S, Han Y, Pande M, Cheng I, Rudd J, Pierce BL, Nutter EL, Schumacher FR, Kote-Jarai Z, Lindstrom S, Witte JS, Fang S, Han J, Kraft P, Hunter DJ, Song F, Hung RJ, McKay J, Gruber SB, Chanock SJ, Risch A, Shen H, Haiman CA, Boardman L, Ulrich CM, Casey G, Peters U, Amin Al Olama A, Berchuck A, Berndt SI, Bezieau S, Brennan P, Brenner H, Brinton L, Caporaso N, Chan AT, Chang-Claude J, Christiani DC, Cunningham JM, Easton D, Eeles RA, Eisen T, Gala M, Gallinger SJ, Gayther SA, Goode EL, Grönberg H, Henderson BE, Houlston R, Joshi AD, Küry S, Landi MT, Le Marchand L, Muir K, Newcomb PA, Permuth-Wey J, Pharoah P, Phelan C, Potter JD, Ramus SJ, Risch H, Schildkraut J, Slattery ML, Song H, Wentzensen N, White E, Wiklund F, Zanke BW, Sellers TA, Zheng W, Chatterjee N, Amos CI, Doherty JA, GECCO and the GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI, and TRICL. Telomere structure and maintenance gene variants and risk of five cancer types. Int J Cancer 139(12):2655-2670, 2016. e-Pub 2016. PMID: 27459707.
- Vaysse A, Fang S, Brossard M, Wei Q, Chen WV, Mohamdi H, Vincent-Fetita L, Margaritte-Jeannin P, Lavielle N, Maubec E, Lathrop M, Avril MF, Amos CI, Lee JE, Demenais F. A comprehensive genome-wide analysis of melanoma Breslow thickness identifies interaction between CDC42 and SCIN genetic variants. Int J Cancer 139(9):2012-20, 2016. e-Pub 2016. PMID: 27347659.
- Fang S, Sui D, Wang Y, Liu H, Chiang YJ, Ross MI, Gershenwald JE, Cormier JN, Royal RE, Lucci A, Wargo J, Hu MI, Gardner JM, Reveille JD, Bassett RL, Wei Q, Amos CI, Lee JE. Association of Vitamin D Levels With Outcome in Patients With Melanoma After Adjustment For C-Reactive Protein. J Clin Oncol 34(15):1741-1747, 2016. e-Pub 2016. PMID: 27001565.
- Brossard M, Fang S, Vaysse A, Wei Q, Chen WV, Mohamdi H, Maubec E, Lavielle N, Galan P, Lathrop M, Avril MF, Lee JE, Amos CI, Demenais F. Integrated pathway and epistasis analysis reveals interactive effect of genetic variants at TERF1 and AFAP1L2 loci on melanoma risk. Int J Cancer 137(8):1901-1909, 2015. e-Pub 2015. PMID: 25892537.
- Fang S, Wang Y, Chun YS, Liu H, Ross MI, Gershenwald JE, Cormier JN, Royal RE, Lucci A, Schacherer CW, Reveille JD, Chen W, Sui D, Bassett RL, Wang LE, Wei Q, Amos CI, Lee JE. Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk and Outcomes. J Invest Dermatol 135(9):2266-2272, 2015. e-Pub 2015. PMID: 25848976.
- Law MH, Bishop DT, Lee JE, Brossard M, Martin NG, Moses EK, Song F, Barrett JH, Kumar R, Easton DF, Pharoah PD, Swerdlow AJ, Kypreou KP, Taylor JC, Harland M, Randerson-Moor J, Akslen LA, Andresen PA, Avril MF, Azizi E, Scarrà GB, Brown KM, D?bniak T, Duffy DL, Elder DE, Fang S, Friedman E, Galan P, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Helsing P, Hocevar M, Höiom V, Ingvar C, Kanetsky PA, Chen WV, GenoMEL Consortium, Essen-Heidelberg Investigators, SDH Study Group, Q-MEGA and QTWIN Investigators, AMFS Investigators, ATHENS Melanoma Study Group, Landi MT, Lang J, Lathrop GM, Lubinski J, Mackie RM, Mann GJ, Molven A, Montgomery GW, Novakovic S, Olsson H, Puig S, Puig-Butille JA, Qureshi AA, Radford-Smith GL, van der Stoep N, van Doorn R, Whiteman DC, Craig JE, Schadendorf D, Simms LA, Burdon KP, Nyholt DR, Pooley KA, Orr N, Stratigos AJ, Cust AE, Ward SV, Hayward NK, Han J, Schulze HJ, Dunning AM, Bishop JA, Demenais F, Amos CI, MacGregor S, Iles MM. Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Nat Genet 47:987-995, 2015. e-Pub 2015. PMID: 26237428.
- Zhang W, Liu H, Liu Z, Zhu D, Amos CI, Fang S, Lee JE, Wei Q. Functional Variants in Notch Pathway Genes NCOR2, NCSTN, and MAML2 Predict Survival of Patients with Cutaneous Melanoma. Cancer Epidemiol Biomarkers Prev 24(7):1101-10, 2015. e-Pub 2015. PMID: 25953768.
- Fang S, Wang Y, Chun YS, Liu H, Ross MI, Gershenwald JE, Cormier JN, Royal RE, Lucci A, Schacherer CW, Reveille JD, Sui D, Bassett RL, Wang LE, Wei Q, Amos CI, Lee JE. The relationship between blood IL-12p40 level and melanoma progression. Int J Cancer 136(8):1874-80, 2015. e-Pub 2014. PMID: 25196740.
- Fang S, Wang Y, Sui D, Liu H, Ross MI, Gershenwald JE, Cormier JN, Royal RE, Lucci A, Schacherer CW, Gardner JM, Reveille JD, Bassett RL, Wang LE, Wei Q, Amos CI, Lee JE. C-reactive protein as a marker of melanoma progression. J Clin Oncol 33(12):1389-1396, 2015. e-Pub 2015. PMID: 25779565.
- Yin J, Liu H, Liu Z, Wang LE, Chen WV, Zhu D, Amos CI, Fang S, Lee JE, Wei Q. Genetic variants in Fanconi Anemia Pathway Genes BRCA2 and FANCA Predict Melanoma Survival. J Invest Dermatol 135(2):542-550, 2015. e-Pub 2014. PMID: 25243787.
- Yang L, Lu X, Deng J, Zhou Y, Huang D, Qiu F, Yang X, Yang R, Fang W, Ran P, Zhong N, Zhou Y, Fang S, Lu J. Risk factors shared by COPD and lung cancer and mediation effect of COPD: two center case-control studies. Cancer Causes Control 26(1):11-24, 2015. e-Pub 2014. PMID: 25488825.
- Song F, Amos CI, Lee JE, Lian CG, Fang S, Liu H, MacGregor S, Iles MM, Lindeman NI, Montgomery GW, Duffy DL, Cust AE, Jenkins MA, Whiteman DC, Kefford RF, Giles GG, Armstrong BK, Aitken JF, Hopper JL, Brown KM, Martin NG, Mann GJ, Bishop DT, Newton Bishop JA, the GenoMEL consortium, Kraft P, Qureshi AA, Kanetsky PA, Hayward NK, Hunter DJ, Wei Q, Han J. Identification of a melanoma susceptibility locus and somatic mutation in TET2. Carcinogenesis 35(9):2097-101, 2014. e-Pub 2014. PMID: 24980573.
- Xiao F, Ma J, Cai G, Fang S, Lee JE, Wei Q, Amos CI. Natural and orthogonal model for estimating gene-gene interactions applied to cutaneous melanoma. Hum Genet 133(5):559-74, 2014. e-Pub 2013. PMID: 24241239.
- Fang S, Zhang M, Wang L, Wei Q, Amos CI, Lee JE. Joint effect of multiple common SNPs predicts melanoma susceptibility. PLOS One 8(12), 2013. e-Pub 2013.
- Park JY, Amankwah EK, Anic GM, Lin HY, Walls B, Park H, Krebs K, Madden M, Maddox K, Marzban S, Fang S, Chen W, Lee JE, Wei Q, Amos CI, Messina JL, Sondak VK, Sellers TA, Egan KM. Gene variants in angiogenesis and lymphangiogenesis and cutaneous melanoma progression. Cancer Epidemiol Biomarkers Prev 22(5):827-34, 2013. e-Pub 2013. PMID: 23462921.
- Iles MM, Law MH, Stacey SN, Han J, Fang S, Pfeiffer R, Harland M, Macgregor S, Taylor JC, Aben KK, Akslen LA, Avril MF, Azizi E, Bakker B, Benediktsdottir KR, Bergman W, Scarrà GB, Brown KM, Calista D, Chaudru V, Fargnoli MC, Cust AE, Demenais F, de Waal AC, Debniak T, Elder DE, Friedman E, Galan P, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Helsing P, Hocevar M, Höiom V, Hopper JL, Ingvar C, Janssen M, Jenkins MA, Kanetsky PA, Kiemeney LA, Lang J, Lathrop GM, Leachman S, Lee JE, Lubinski J, Mackie RM, Mann GJ, Martin NG, Mayordomo JI, Molven A, Mulder S, Nagore E, Novakovic S, Okamoto I, Olafsson JH, Olsson H, Pehamberger H, Peris K, Grasa MP, Planelles D, Puig S, Puig-Butille JA, Randerson-Moor J, Requena C, Rivoltini L, Rodolfo M, Santinami M, Sigurgeirsson B, Snowden H, Song F, Sulem P, Thorisdottir K, Tuominen R, Van Belle P, van der Stoep N, van Rossum MM, Wei Q, Wendt J, Zelenika D, Zhang M, Landi MT, Thorleifsson G, Bishop DT, Amos CI, Hayward NK, Stefansson K, Bishop JA, Barrett JH, GenoMEL Consortium, Q-MEGA and AMFS Investigators. A variant in FTO shows association with melanoma risk not due to BMI. Nat Genet 45(4):428-32, 432e1, 2013. e-Pub 2013. PMID: 23455637.
- Gorlov IP, Logothetis CJ, Fang S, Gorlova OY, Amos CI. Building a Statistical Model for Predicting Cancer Genes. PLOS One 7(11):e49175, 2012.
- Bodelon C, Pfeiffer RM, Bollati V, Debbache J, Calista D, Ghiorzo P, Fargnoli MC, Bianchi-Scarra G, Peris K, Hoxha M, Hutchinson A, Burdette L, Burke L, Fang S, Tucker MA, Goldstein AM, Lee JE, Wei Q, Savage SA, Yang XR, Amos CI, MariLandi MT. On the Interplay of Telomeres, Nevi and the Risk of Melanoma. PLOS ONE 7(12):e52466, 2012. e-Pub 2012.
- Fang S, Krahe R, Bachinski LL, Zhang B, Amos CI, Strong LC. Sex-specific effect of the TP53 PIN3 polymorphism on cancer risk in a cohort study of TP53 germline mutation carriers. Hum Genet 130(6):789-94, 2011. e-Pub 2011. PMID: 21688173.
- Amos CI, Wang LE, Lee JE, Gershenwald JE, Chen WV, Fang S, Kosoy R, Zhang M, Qureshi AA, Vattathil S, Schacherer CW, Gardner JM, Wang Y, Bishop DT, Barrett JH, GenoMEL Investigators, MacGregor S, Hayward NK, Martin NG, Duffy DL, Q-Mega Investigators, Mann GJ, Cust A, Hopper J, AMFS Investigators, Brown KM, Grimm EA, Xu Y, Han Y, Jing K, McHugh C, Laurie CC, Doheny KF, Pugh EW, Seldin MF, Han J, Wei Q. Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet 20(24):5012-23, 2011. e-Pub 2011. PMID: 21926416.
- Barrett JH, Iles MM, Harland M, Taylor JC, Aitken JF, Andresen PA, Akslen LA, Armstrong BK, Avril MF, Azizi E, Bakker B, Bergman W, Bianchi-Scarrà G, Bressac-de Paillerets B, Calista D, Cannon-Albright LA, Corda E, Cust AE, Debniak T, Duffy D, Dunning AM, Easton DF, Friedman E, Galan P, Ghiorzo P, Giles GG, Hansson J, Hocevar M, Höiom V, Hopper JL, Ingvar C, Janssen B, Jenkins MA, Jönsson G, Kefford RF, Landi G, Landi MT, Lang J, Lubinski J, Mackie R, Malvehy J, Martin NG, Molven A, Montgomery GW, van Nieuwpoort FA, Novakovic S, Olsson H, Pastorino L, Puig S, Puig-Butille JA, Randerson-Moor J, Snowden H, Tuominen R, Van Belle P, van der Stoep N, Whiteman DC, Zelenika D, Han J, Fang S, Lee JE, Wei Q, Lathrop GM, Gillanders EM, Brown KM, Goldstein AM, Kanetsky PA, Mann GJ, Macgregor S, Elder DE, Amos CI, Hayward NK, Gruis NA, Demenais F, Bishop JA, Bishop DT, GenoMEL Consortium. Genome-wide association study identifies three new melanoma susceptibility loci. Nat Genet 43(11):1108-13, 2011. e-Pub 2011. PMID: 21983787.
- Chavez-MacGregor M, Zhao H, Kroll M, Fang S, Zhang N, Hortobagyi GN, Buchholz TA, Shih YC, Giordano SH.. Risk factors and incidence of thromboembolic events (TEEs) in older men and women with breast cancer. Annals of Oncology 22(11):2394-402, 2011.
- Chavez-MacGregor M, Zhao H, Fang S, Srokowski TP, Hortobagyi GN, Giordano SH. Complications associated with erythropoietin-stimulating agents in patients with metastatic breast cancer: a Surveillance, Epidemiology, and End Results-Medicare study. Cancer 117(16):3641-9, 2011. e-Pub 2011. PMID: 21656514.
- Fang S, Fang X, Xiong M. Psoriasis prediction from genome-wide SNP profiles. BMC Dermatol 11:1, 2011. e-Pub 2011. PMID: 21214922.
- Fang S, Pinney SM, Bailey-Wilson JE, de Andrade MA, Li Y, Kupert E, You M, Schwartz AG, Yang P, Anderson MW, Amos CI. Ordered subset analysis identifies loci influencing lung cancer risk on chromosomes 6q and 12q. Cancer Epidemiol Biomarkers Prev 19(12):3157-66, 2010. e-Pub 2010. PMID: 21030603.
- Fang S, Krahe R, Lozano G, Han Y, Chen W, Post SM, Zhang B, Wilson CD, Bachinski LL, Strong LC, Amos CI. Effects of MDM2, MDM4 and TP53 codon 72 polymorphisms on cancer risk in a cohort study of carriers of TP53 germline mutations. PLoS One 5(5):e10813, 2010. e-Pub 2010. PMID: 20520810.
- Srokowski TP, Fang S, Hortobagyi GN, Giordano SH. Impact of diabetes mellitus on complications and outcomes of adjuvant chemotherapy in older patients with breast cancer. J Clin Oncol 27(13):2170-6, 2009. e-Pub 2009. PMID: 19307509.
- Wang M, Burau KD, Fang S, Wang H, Du XL. Ethnic variations in diagnosis, treatment, socioeconomic status, and survival in a large population-based cohort of elderly patients with non-Hodgkin lymphoma. Cancer 113(11):3231-41, 2008. PMID: 18937267.
- Srokowski TP, Fang S, Duan Z, Buchholz TA, Hortobagyi GN, Goodwin JS, Giordano SH. Completion of adjuvant radiation therapy among women with breast cancer. Cancer 113(1):22-9, 2008. PMID: 18442124.
- Buchholz TA, Woodward WA, Duan Z, Fang S, Oh JL, Tereffe W, Strom EA, Perkins GH, Yu TK, Hunt KK, Meric-Bernstam F, Hortobagyi GN, Giordano SH. Radiation use and long-term survival in breast cancer patients with T1, T2 primary tumors and one to three positive axillary lymph nodes. Int J Radiat Oncol Biol Phys 71(4):1022-7, 2008. e-Pub 2008. PMID: 18234447.
- Giordano SH, Fang S, Duan Z, Kuo YF, Hortobagyi GN, Goodwin JS. Use of intravenous bisphosphonates in older women with breast cancer. Oncologist 13(5):494-502, 2008. PMID: 18515734.
- Badgwell BD, Giordano SH, Duan ZZ, Fang S, Bedrosian I, Kuerer HM, Singletary SE, Hunt KK, Hortobagyi GN, Babiera G. Mammography before diagnosis among women age 80 years and older with breast cancer. J Clin Oncol 26(15):2482-8, 2008. e-Pub 2008. PMID: 18427152.
- Rohatgi N, Du XL, Coker AL, Moye LA, Wang M, Fang S. Chemotherapy and survival for patients with multiple myeloma: findings from a large nationwide and population-based cohort. Am J Clin Oncol 30(5):540-8, 2007. PMID: 17921717.
- Patt DA, Duan Z, Fang S, Hortobagyi GN, Giordano SH. Acute myeloid leukemia after adjuvant breast cancer therapy in older women: understanding risk. J Clin Oncol 25(25):3871-6, 2007. e-Pub 2007. PMID: 17664457.
- Du XL, Lairson DR, Begley CE, Fang S. Temporal and geographic variation in the use of hematopoietic growth factors in older women receiving breast cancer chemotherapy: findings from a large population-based cohort. J Clin Oncol 23(34):8620-8, 2005. PMID: 16314624.
- Fang S, Xu T, Xiong M, Zhou X, Wang Y, Haydu LE, Ross MI, Gershenwald JE, Prieto VG, Cormier JN, Wargo J, Sui D, Wei Q, Amos CI, Lee JE. Role of Immune Response, Inflammation, and Tumor Immune Response-Related Cytokines/Chemokines in Melanoma Progression. J Invest Dermatol. e-Pub 2019. PMID: 31176707.
Invited Articles
- Fang S, Wang Y, Lu M, Dang Y, Li M,Koshkina N, Feng R, Liu H, Xu K, Sui D, Wei Q, Amos CI, Lee JE. Association of Inflammation-related Genetic Variants with Melanoma Development. Journal of Experimental Dermatology and Research 1(3):012, 2015.
Abstracts
- Fang S, Wang Y, Ross MI, Gershenwald JE, Cormier JN, Royal RE, Reveille JD, Wei Q, Amos CI, Lee JE. CDKN2A germline mutation and somatic mutation show opposite associations with clinical outcomes in melanoma patients. American Society of Human Genetics 67th Annual Meeting, 2017.
- Fang S, Wang Y, Deng D, Liu Q, Feng R, Xu K, Liu H, Ross MI, Gershenwald JE , Cormier JN, Royal, Lucci A, Wargo J, Schacherer CW, Reveille JD, GenoMEL group, Demenais F, Wang L, Lu M, Wei Q, Amos CI, Lee JE. Genetic determinants of Breslow tumor thickness and their impact on melanoma progression. American Society of Human Genetics 64th Annual Meeting, 2014.
- Fang S, Han J, Zhang M, Wang L, Wei Q, Amos CI, Lee JE. Joint Effect of Multiple Common SNPs Predicts Melanoma Susceptibility. American Society of Human Genetics 63rd Annual Meeting, 2013.
- Fang S, Wang Y, Sui D, Liu H, Schacherer CW, Gardner JM, Ross MI, Gershenwald JE, Reveille JD, Wang L, Wei Q, Amos CI, Lee JE. C Reactive Protein as a Prognostic Marker in Melanoma Progression. The American Society of Human Genetics Conference, 2012.
- Fang S, Wang L, Gershenwald J, Chen W, Schacherer CW, Gardner JM, Wang Y, Bishop DT, Barrett JH, Grimm EA, McHugh C, Laurie C, Doheny KF, Pugh EW, Wei Q, Amos CI, Lee JE. Genome-Wide Association Study of Melanoma Progression and Blood Biomarkers. 12th International Congress of Human Genetics/61st ASHG Annual Meeting, 2011.
- Fang S, Pinney SM, Bailey-Wilson JE, de Andrade MA, Li Y, Kupert E, You M, Schwartz AG, Yang P, Anderson MW, Amos CI. Ordered subset analysis identifies loci influencing lung cancer risk on chromosomes 6q and 12q. The 19th Annual Meeting of the International Genetic Epidemiology Society, 2010.
- Fang S, Krahe R, Lozano G, Han Y, Chen W, Post SM, Zhang B, Wilson CD, Bachinski LL, Strong LC, Amos CI. Effects of MDM2, MDM4 and TP53 Codon 72 Polymorphisms on Cancer Risk in A Cohort Study of Carriers of TP53 Germline Mutations. The University of Texas MD Anderson Cancer Center Trainee Research Day 2010, 2010.
- Fang S, Fang X, Xiong M. Psorasis prediction from genome-wide SNP profiles. The 59th Annual Meeting of the American Society of Human Genetics, 2009.
- Song S, Burau KD, Fang S, Wang H, Du XL, Wang L. Ethnic Variations in Diagnosis, Treatment, Socioeconomic Status and Survival in a Large Population-Based Cohort of Elderly Patients with Non-Hodgkin’s Lymphoma. Amercian Society of Hematology 50th Annual Meeting, 2008.
- Du XL, Fang S, Coker AL, Sanderson M, Aragaki C, Cormier JN, Xing Y, Gor BJ, Chan W. Racial Disparities and Socioeconomic Status in Association with Survival in Older Men with Local/Regional Stage Prostate Cancer. Academy Health Annual Meeting, 2006.
Letters to the Editor
- Fang S, Wang Y, Amos CI, Lee JE. Reply to Z. Li et al. J Clin Oncol 33: 3674-5, 2015.
Grant & Contract Support
| Title: | Genetic polymorphisms of IL-12p35 and IL-23p19 in melanoma progression |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator |
| Title: | Genetic determinants of Breslow tumor thickness and their impact on melanoma progression |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator |
| Title: | C-reactive protein and melanoma outcomes |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator |
| Title: | Integration of Clinical and Molecular Biomarkers for Melanoma Survival |
| Funding Source: | NIH/NCI |
| Role: | Co-Investigator |
| Title: | The skin microbiome and cutaneous melanoma |
| Funding Source: | UT MD Anderson |
| Role: | Principal Investigator |