Yang O. Huh, MD
Department of Hematopathology, Division of Pathology and Laboratory Medicine
Present Title & Affiliation
Primary Appointment
Professor, Department of Hematopathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center (UTMDACC), Houston, TX
Education & Training
Degree-Granting Education
| 1974 | Yonsei University Medical College, Seoul, MD |
Postgraduate Training
| 1983-1984 | Fellowship in Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 1980-1981 | Fellowship in Blood Banking, New York Blood Center, New York, NY |
| 1977-1980 | Resident in Anatomical and Clinical Pathology, New York Medical College, Metropolitan Hospital Center, New York, NY |
| 1976-1977 | Pathology Resident, Muhlenberg Hospital, Plainfield, NJ |
| 1975-1976 | Pathology Resident, Yonsei University, College of Medicine, Seoul |
| 1974-1975 | Clinical Internship, Yonsei University Medical Center Severance Hospital, Seoul |
Board Certifications
| 1984 | American Board of Pathology (Blood Banking) |
| 1980 | American Board of Pathology (Anatomical and Clinical Pathology) |
Honors & Awards
| 1974 | Graduated with Honors , Yonsei University College of Medicine |
Selected Publications
Peer-Reviewed Articles
- Quesada AE, Huh YO, Wang W, Medeiros LJ, Thakral B. Anaplastic lymphoma kinase (ALK)-positive large B-cell lymphoma in a patient treated with azathioprine for ulcerative colitis. Pathology 48(5):513-5, 2016. e-Pub 2016. PMID: 27311871.
- Huh YO, Tang G, Talwalkar SS, Khoury JD, Ohanian M, Bueso-Ramos CE, Abruzzo LV. Double minute chromosomes in acute myeloid leukemia, myelodysplastic syndromes, and chronic myelomonocytic leukemia are associated with micronuclei, MYC or MLL amplification, and complex karyotype. Cancer Genet 209(7-8):313-20, 2016. e-Pub 2016. PMID: 27318442.
- Chakhachiro Z, Yin CC, Abruzzo LV, Aladily TN, Barron LL, Banks HE, Thomas DA, Keating M, Medeiros LJ, Huh YO. B-Lymphoblastic Leukemia in Patients With Chronic Lymphocytic Leukemia: A Report of Four Cases. Am J Clin Pathol 144(2):333-40, 2015. PMID: 26185320.
- Schweighofer CD, Huh YO, Luthra R, Sargent RL, Ketterling RP, Knudson RA, Barron LL, Medeiros LJ, Keating MJ, Abruzzo LV. The B cell antigen receptor in atypical chronic lymphocytic leukemia with t(14;19)(q32;q13) demonstrates remarkable stereotypy. Int J Cancer 128(11):2759-64, 2011. e-Pub 2010. PMID: 20715110.
- Huh YO, Schweighofer CD, Ketterling RP, Knudson RA, Vega F, Kim JE, Luthra R, Keating MJ, Medeiros LJ, Abruzzo LV. Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features. Am J Clin Pathol 135(5):686-96, 2011. PMID: 21502423.
- Huh YO, Medeiros LJ, Ravandi F, Konoplev S, Jorgensen JL, Miranda RN. T-cell large granular lymphocyte leukemia associated with myelodysplastic syndrome: a clinicopathologic study of nine cases. Am J Clin Pathol 131(3):347-56, 2009. PMID: 19228641.
- Johnson MR, Verstovsek S, Jorgensen JL, Manshouri T, Luthra R, Jones DM, Bueso-Ramos CE, Medeiros LJ, Huh YO. Utility of the World Heath Organization classification criteria for the diagnosis of systemic mastocytosis in bone marrow. Mod Pathol 22(1):50-7, 2009. e-Pub 2008. PMID: 19116630.
- Huh YO, Lin KI, Vega F, Schlette E, Yin CC, Keating MJ, Luthra R, Medeiros LJ, Abruzzo LV. MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis. Br J Haematol 142(1):36-44, 2008. PMID: 18477041.
- Huh YO, Abruzzo LV, Rassidakis GZ, Parry-Jones N, Schlette E, Brito-Bapabulle V, Matutes E, Wotherspoon A, Keating MJ, Medeiros LJ, Catovsky D. The t(14;19)(q32;q13)-positive small B-cell leukaemia: a clinicopathologic and cytogenetic study of seven cases. Br J Haematol 136(2):220-8, 2007. PMID: 17129229.
- Merzianu M, Medeiros LJ, Cortes J, Yin C, Lin P, Jones D, Glassman A, Kantarjian H, Huh Y. inv(16)(p13q22) in chronic myelogenous leukemia in blast phase: a clinicopathologic, cytogenetic, and molecular study of five cases. Am J Clin Pathol 124(5):807-14, 2005. PMID: 16203287.
- Gu J, Huh YO, Jiang F, Caraway NP, Romaguera JE, Zaidi TM, Fernandez RL, Zhang H, Khouri IF, Katz RL. Evaluation of peripheral blood involvement of mantle cell lymphoma by fluorescence in situ hybridization in comparison with immunophenotypic and morphologic findings. Mod Pathol 17(5):553-60, 2004. PMID: 15001994.
- Lin P, Hao S, Medeiros LJ, Estey EH, Pierce SA, Wang X, Glassman AB, Bueso-Ramos C, Huh YO. Expression of CD2 in acute promyelocytic leukemia correlates with short form of PML-RARalpha transcripts and poorer prognosis. Am J Clin Pathol 121(3):402-7, 2004. PMID: 15023045.
- Huh YO, Jilani I, Estey E, Giles F, Kantarjian H, Freireich E, Albitar M. More cell death in refractory anemia with excess blasts in transformation than in acute myeloid leukemia. Leukemia 16(11):2249-52, 2002. PMID: 12399969.
- Onciu M, Berrak SG, Medeiros LJ, Katz RL, Huh YO. Discrepancies in the immunophenotype of lymphoma cells in samples obtained simultaneously from different anatomic sites. Am J Clin Pathol 117(4):644-50, 2002. PMID: 11939741.
- Huh YO, Keating MJ, Saffer HL, Jilani I, Lerner S, Albitar M. Higher levels of surface CD20 expression on circulating lymphocytes compared with bone marrow and lymph nodes in B-cell chronic lymphocytic leukemia. Am J Clin Pathol 116(3):437-43, 2001. PMID: 11554173.
- Jones D, Dang NH, Duvic M, Washington LT, Huh YO. Absence of CD26 expression is a useful marker for diagnosis of T-cell lymphoma in peripheral blood. Am J Clin Pathol 115(6):885-92, 2001. PMID: 11392886.
- Huh YO, Ibrahim S. Immunophenotypes in adult acute lymphocytic leukemia. Role of flow cytometry in diagnosis and monitoring of disease. Hematol Oncol Clin North Am 14(6):1251-65, 2000. PMID: 11147222.
- Huh YO, Smith TL, Collins P, Bueso-Ramos C, Albitar M, Kantarjian HM, Pierce SA, Freireich EJ. Terminal deoxynucleotidyl transferase expression in acute myelogenous leukemia and myelodysplasia as determined by flow cytometry. Leuk Lymphoma 37(3-4):319-31, 2000. PMID: 10752983.
- Huh YO, Andreeff M. Flow cytometry. Clinical and research applications in hematologic malignancies. Hematol Oncol Clin North Am 8(4):703-23, 1994. PMID: 7961287.
Abstracts
- Huh YO, Forgetta J, Kantarjian H, Stass S, Keating M. Detection of subgroups of chronic B cell leukemias by FMC7 monoclonal antibody. Blood 76:282a, 1990.
- Huh YO, Liu FJ, Rogge K, Chakrabarty L, Lichtiger B. Positive direct antiglobulin test and high serum immunoglobulin G level. Am J Clin Pathol 87:419, 1987.