Yupeng Li, M.S., DABR
Department of Radiation Physics, Division of Radiation Oncology - Clinical
Present Title & Affiliation
Primary Appointment
Sr. Medial Physicist, Department of Radiation Physics - Patient Care, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2005 | University of Houston, Houston, TX, USA, MS, Mathematics |
| 2003 | University of Houston, Houston, TX, USA, MS, Computer Science |
| 1999 | University of Science and Technology of China, Hefei, AL, CHN, BS, Science and Technology |
Board Certifications
| 2013 | American Board of Radiology (DABR) |
Experience & Service
Academic Appointments
Visiting Scientist, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2017
Computational Scientist, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2007 - 2012
Sr. Research Assistant, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2005 - 2007
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Wang X, Li H, Zhu XR, Hou Q, Liao L, Jiang B, Li Y, Wang P, Lang J, Zhang X. Multiple-CT optimization of intensity-modulated proton therapy - Is it possible to eliminate adaptive planning?. Radiother Oncol 128(1):167-173, 2018. e-Pub 2017. PMID: 29054378.
- Wang X, Li Y, Zhang X, Li H, Miyazaki K, Fujimoto R, Akiyama H, Gillin MT, Poenisch F, Sahoo N, Grosshans D, Gunn B, Frank SJ, Wang P, Lang J, Hou Q, Zhu XR. Synchrotron-Based Pencil Beam Scanning Nozzle with an Integrated Mini-Ridge Filter: A Dosimetric Study to Optimize Treatment Delivery. Cancers (Basel) 9(12), 2017. e-Pub 2017. PMID: 29236051.
- Wang L, Wang X, Li Y, Han S, Zhu J, Wang X, Molkentine DP, Blanchard P, Yang Y, Zhang R, Sahoo N, Gillin M, Zhu XR, Zhang X, Myers JN, Frank SJ. Human papillomavirus status and the relative biological effectiveness of proton radiotherapy in head and neck cancer cells. Head Neck 39(4):708-715, 2017. e-Pub 2016. PMID: 28039958.
- Yu J, Zhang X, Liao L, Li H, Zhu R, Park PC, Sahoo N, Gillin M, Li Y, Chang JY, Komaki R, Lin SH. Motion-robust intensity-modulated proton therapy for distal esophageal cancer. Med Phys 43(3):1111-8, 2016. PMID: 26936698.
- Li Y, Niemela P, Liao L, Jiang S, Li H, Poenisch F, Zhu XR, Siljamaki S, Vanderstraeten R, Sahoo N, Gillin M, Zhang X. Selective robust optimization: A new intensity-modulated proton therapy optimization strategy. Med Phys 42(8):4840-7, 2015. PMID: 26233211.
- Zhu XR, Li Y, Mackin D, Li H, Poenisch F, Lee AK, Mahajan A, Frank SJ, Gillin MT, Sahoo N, Zhang X. Towards effective and efficient patient-specific quality assurance for spot scanning proton therapy. Cancers (Basel) 7(2):631-47, 2015. e-Pub 2015. PMID: 25867000.
- Cao W, Lim GJ, Li Y, Zhu XR, Zhang X. Improved beam angle arrangement in intensity modulated proton therapy treatment planning for localized prostate cancer. Cancers (Basel) 7(2):574-84, 2015. e-Pub 2015. PMID: 25831258.
- Li H, Zhang X, Park P, Liu W, Chang J, Liao Z, Frank S, Li Y, Poenisch F, Mohan R, Gillin M, Zhu R. Robust optimization in intensity-modulated proton therapy to account for anatomy changes in lung cancer patients. Radiother Oncol 114(3):367-72, 2015. e-Pub 2015. PMID: 25708992.
- Liu W, Liao Z, Schild SE, Liu Z, Li H, Li Y, Park PC, Li X, Stoker J, Shen J, Keole S, Anand A, Fatyga M, Dong L, Sahoo N, Vora S, Wong W, Zhu XR, Bues M, Mohan R. Impact of respiratory motion on worst-case scenario optimized intensity modulated proton therapy for lung cancers. Pract Radiat Oncol 5(2):e77-86, 2015. e-Pub 2014. PMID: 25413400.
- Kardar L, Li Y, Li X, Li H, Cao W, Chang JY, Liao L, Zhu RX, Sahoo N, Gillin M, Liao Z, Komaki R, Cox JD, Lim G, Zhang X. Evaluation and mitigation of the interplay effects of intensity modulated proton therapy for lung cancer in a clinical setting. Pract Radiat Oncol 4(6):e259-68, 2014. e-Pub 2014. PMID: 25407877.
- Liu W, Mohan R, Park P, Liu Z, Li H, Li X, Li Y, Wu R, Sahoo N, Dong L, Zhu XR, Grosshans DR. Dosimetric benefits of robust treatment planning for intensity modulated proton therapy for base-of-skull cancers. Pract Radiat Oncol 4(6):384-91, 2014. e-Pub 2014. PMID: 25407859.
- Cao W, Lim G, Liao L, Li Y, Jiang S, Li X, Li H, Suzuki K, Zhu XR, Gomez D, Zhang X. Proton energy optimization and reduction for intensity-modulated proton therapy. Phys Med Biol 59(21):6341-54, 2014. e-Pub 2014. PMID: 25295881.
- Chang JY, Li H, Zhu XR, Liao Z, Zhao L, Liu A, Li Y, Sahoo N, Poenisch F, Gomez DR, Wu R, Gillin M, Zhang X. Clinical implementation of intensity modulated proton therapy for thoracic malignancies. Int J Radiat Oncol Biol Phys 90(4):809-18, 2014. e-Pub 2014. PMID: 25260491.
- Li H, Liu W, Park P, Matney J, Liao Z, Chang J, Zhang X, Li Y, Zhu RX. Evaluation of the systematic error in using 3D dose calculation in scanning beam proton therapy for lung cancer. J Appl Clin Med Phys 15(5):4810, 2014. e-Pub 2014. PMID: 25207565.
- Li Y, Kardar L, Li X, Li H, Cao W, Chang JY, Liao L, Zhu RX, Sahoo N, Gillin M, Liao Z, Komaki R, Cox JD, Lim G, Zhang X. On the interplay effects with proton scanning beams in stage III lung cancer. Med Phys 41(2):021721, 2014. PMID: 24506612.
- Li H, Park P, Liu W, Matney J, Liao Z, Balter P, Li Y, Zhang X, Li X, Zhu XR. Patient-specific quantification of respiratory motion-induced dose uncertainty for step-and-shoot IMRT of lung cancer. Med Phys 40(12):121712, 2013. PMID: 24320498.
- Mackin D, Li Y, Taylor MB, Kerr M, Holmes C, Sahoo N, Poenisch F, Li H, Lii J, Amos R, Wu R, Suzuki K, Gillin MT, Zhu XR, Zhang X. Improving spot-scanning proton therapy patient specific quality assurance with HPlusQA, a second-check dose calculation engine. Med Phys 40(12):121708, 2013. PMID: 24320494.
- Quan EM, Liu W, Wu R, Li Y, Frank SJ, Zhang X, Zhu XR, Mohan R. Preliminary evaluation of multifield and single-field optimization for the treatment planning of spot-scanning proton therapy of head and neck cancer. Med Phys 40(8):081709, 2013. PMID: 23927306.
- Cao W, Lim G, Li X, Li Y, Zhu XR, Zhang X. Incorporating deliverable monitor unit constraints into spot intensity optimization in intensity-modulated proton therapy treatment planning. Phys Med Biol 58(15):5113-25, 2013. e-Pub 2013. PMID: 23835656.
- Li X, Quan EM, Li Y, Pan X, Zhou Y, Wang X, Du W, Kudchadker RJ, Johnson JL, Kuban DA, Lee AK, Zhang X. A fully automated method for CT-on-rails-guided online adaptive planning for prostate cancer intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys 86(5):835-41, 2013. e-Pub 2013. PMID: 23726001.
- Liu W, Frank SJ, Li X, Li Y, Park PC, Dong L, Ronald Zhu X, Mohan R. Effectiveness of robust optimization in intensity-modulated proton therapy planning for head and neck cancers. Med Phys 40(5):051711, 2013. PMID: 23635259.
- Liu W, Frank SJ, Li X, Li Y, Zhu RX, Mohan R. PTV-based IMPT optimization incorporating planning risk volumes vs robust optimization. Med Phys 40(2):021709, 2013. PMID: 23387732.
- Li H, Sahoo N, Poenisch F, Suzuki K, Li Y, Li X, Zhang X, Lee AK, Gillin MT, Zhu XR. Use of treatment log files in spot scanning proton therapy as part of patient-specific quality assurance. Med Phys 40(2):021703, 2013. PMID: 23387726.
- Li H, Li Y, Zhang X, Li X, Liu W, Gillin MT, Zhu XR. Dynamically accumulated dose and 4D accumulated dose for moving tumors. Med Phys 39(12):7359-67, 2012. PMID: 23231285.
- Cao W, Lim GJ, Lee A, Li Y, Liu W, Ronald Zhu X, Zhang X. Uncertainty incorporated beam angle optimization for IMPT treatment planning. Med Phys 39(8):5248-56, 2012. PMID: 22894449.
- Quan EM, Li X, Li Y, Wang X, Kudchadker RJ, Johnson JL, Kuban DA, Lee AK, Zhang X. A comprehensive comparison of IMRT and VMAT plan quality for prostate cancer treatment. Int J Radiat Oncol Biol Phys 83(4):1169-78, 2012. PMID: 22704703.
- Liu W, Zhang X, Li Y, Mohan R. Robust optimization of intensity modulated proton therapy. Med Phys 39(2):1079-91, 2012. PMID: 22320818.
- Li Y, Zhu RX, Sahoo N, Anand A, Zhang X. Beyond Gaussians: a study of single-spot modeling for scanning proton dose calculation. Phys Med Biol 57(4):983-97, 2012. e-Pub 2012. PMID: 22297324.
- Zhang X, Liu W, Li Y, Li X, Quan M, Mohan R, Anand A, Sahoo N, Gillin M, Zhu XR. Parameterization of multiple Bragg curves for scanning proton beams using simultaneous fitting of multiple curves. Phys Med Biol 56(24):7725-35, 2011. e-Pub 2011. PMID: 22085829.
- Li X, Wang X, Li Y, Zhang X. A 4D IMRT planning method using deformable image registration to improve normal tissue sparing with contemporary delivery techniques. Radiat Oncol 6:83, 2011. e-Pub 2011. PMID: 21771333.
- Zhang X, Li X, Quan EM, Pan X, Li Y. A methodology for automatic intensity-modulated radiation treatment planning for lung cancer. Phys Med Biol 56(13):3873-93, 2011. e-Pub 2011. PMID: 21654043.
- Li Y, Zhang X, Mohan R. An efficient dose calculation strategy for intensity modulated proton therapy. Phys Med Biol 56(4):N71-84, 2011. e-Pub 2011. PMID: 21263173.
- Zhang X, Li Y, Pan X, Xiaoqiang L, Mohan R, Komaki R, Cox JD, Chang JY. Intensity-modulated proton therapy reduces the dose to normal tissue compared with intensity-modulated radiation therapy or passive scattering proton therapy and enables individualized radical radiotherapy for extensive stage IIIB non-small-cell lung cancer: a virtual clinical study. Int J Radiat Oncol Biol Phys 77(2):357-66, 2010. e-Pub 2009. PMID: 19660879.
- Pan X, Zhang X, Li Y, Mohan R, Liao Z. Impact of using different four-dimensional computed tomography data sets to design proton treatment plans for distal esophageal cancer. Int J Radiat Oncol Biol Phys 73(2):601-9, 2009. PMID: 19147024.
- Hui Z, Zhang X, Starkschall G, Li Y, Mohan R, Komaki R, Cox JD, Chang JY. Effects of interfractional motion and anatomic changes on proton therapy dose distribution in lung cancer. Int J Radiat Oncol Biol Phys 72(5):1385-95, 2008. e-Pub 2008. PMID: 18486357.
- Zhang X, Zhao KL, Guerrero TM, McGuire SE, Yaremko B, Komaki R, Cox JD, Hui Z, Li Y, Newhauser WD, Mohan R, Liao Z. Four-dimensional computed tomography-based treatment planning for intensity-modulated radiation therapy and proton therapy for distal esophageal cancer. Int J Radiat Oncol Biol Phys 72(1):278-87, 2008. PMID: 18722278.
- Li Y, Zhang X, Lii M, Sahoo N, Zhu RX, Gillin M, Mohan R. Incorporating partial shining effects in proton pencil-beam dose calculation. Phys Med Biol 53(3):605-16, 2008. e-Pub 2008. PMID: 18199905.
- Li Y, Zhang X, Dong L, Mohan R. A novel patch-field design using an optimized grid filter for passively scattered proton beams. Phys Med Biol 52(12):N265-75, 2007. e-Pub 2007. PMID: 17664545.
- Zhang X, Dong L, Lee AK, Cox JD, Kuban DA, Zhu RX, Wang X, Li Y, Newhauser WD, Gillin M, Mohan R. Effect of anatomic motion on proton therapy dose distributions in prostate cancer treatment. Int J Radiat Oncol Biol Phys 67(2):620-9, 2007. PMID: 17236979.