Zhuang Zuo, MD, PhD

Peer-Reviewed Articles

1. Ye MT, Wang Y, Zuo Z, Calin S, He H, Tang Z, Jabbour EJ, Borthakur G, Zhang Y, Yang Y, You MJ. Integrated clinical genotype-phenotype characteristics of early T-cell precursor acute lymphoblastic leukemia. Cancer 129(1):49-59, 2023. e-Pub 2022. PMID: 36281717.
2. Shuai W, Zuo Z, Li N, Garces S, Jelloul FZ, Ok CY, Li S, Xu J, You MJ, Wang W, Rehder C, Jabbour EJ, Patel KP, Medeiros LJ, Yin CC. ETNK1 mutation occurs in a wide spectrum of myeloid neoplasms and is not specific for atypical chronic myeloid leukemia. Cancer. e-Pub 2022. PMID: 36583229.
3. Fang H, Wang SA, Hu S, Konoplev SN, Mo H, Liu W, Zuo Z, Xu J, Jorgensen JL, Yin CC, El Hussein S, Jelloul FZ, Tang Z, Medeiros LJ, Wang W. Acute promyelocytic leukemia: Immunophenotype and differential diagnosis by flow cytometry. Cytometry B Clin Cytom 102(4):283-291, 2022. e-Pub 2022. PMID: 35716019.
4. Jelloul FZ, Yang R, Garces S, Kanagal-Shamanna R, Ok CY, Loghavi S, Routbort MJ, Zuo Z, Yin CC, Floyd K, Bassett RL, Wierda W, Jain N, Thompson P, Luthra R, Medeiros LJ, Patel KP. Landscape of NOTCH1 mutations and co-occurring biomarker alterations in chronic lymphocytic leukemia. Leuk Res 116:106827, 2022. e-Pub 2022. PMID: 35430388.
5. Jelloul FZ, Yang RK, Wang P, Garces S, Kanagal-Shamanna R, Ok CY, Loghavi S, Routbort MJ, Zuo Z, Yin CC, Floyd K, Bassett RL, Wierda WG, Jain N, Thompson PA, Luthra R, Medeiros LJ, Patel KP. Non-coding NOTCH1 mutations in chronic lymphocytic leukemia negatively impact prognosis. Am J Hematol. e-Pub 2022. PMID: 34989420.
6. Zuo, Z.; Medeiros, L.J.; Garces, S.; Routbort, M.J.; Ok, C.Y.; Loghavi, S.; Kanagal‐Shamanna, R.; Jelloul, F.Z.; Garcia‐Manero, G.; Chien, K.S.; Patel, K.P.; Luthra R.; Yin C.C.. Concurrent Mutations in SF3B1 and PHF6 in Myeloid Neoplasms. Biology, 2022. e-Pub 2022.
7. Sweeney KJ, Tetzlaff MT, Vega F, Gillenwater A, Zuo Z, Gross N, Nagarajan P, Wargo J, Nelson K, Prieto VG, Torres-Cabala CA, Curry JL. Tertiary lymphoid structures with overlapping histopathologic features of cutaneous marginal zone lymphoma during neoadjuvant cemiplimab therapy are associated with antitumor response. J Cutan Pathol. e-Pub 2021. PMID: 33399228.
8. Ye MT, Wang Y, Wang SA, Pemmaraju N, Daver N, Verstovsek S, Zhang Y, Zuo Z, Medeiros LJ, You MJ. Concurrent JAK2 V617F and MPL W515L in myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis. Leuk Lymphoma 61(4):963-966, 2020. e-Pub 2019. PMID: 31750750.
9. Sakhdari A, Thakral B, Loghavi S, Kanagal-Shamanna R, Yin CC, Zuo Z, Routbort MJ, Luthra R, Medeiros LJ, Wang SA, Patel KP, Ok CY. RAS and TP53 can predict survival in adults with T-cell lymphoblastic leukemia treated with hyper-CVAD. Cancer Med 9(3):849-858, 2020. PMID: 31804006.
10. Hu B, Patel KP, Chen HC, Wang X, Luthra R, Routbort MJ, Kanagal-Shamanna R, Medeiros LJ, Yin CC, Zuo Z, Ok CY, Loghavi S, Tang G, Tambaro FP, Thompson P, Burger J, Jain N, Ferrajoli A, Bose P, Estrov Z, Keating M, Wierda WG. Association of gene mutations with time-to-first treatment in 384 treatment-naive chronic lymphocytic leukaemia patients. Br J Haematol 187(3):307-318, 2019. e-Pub 2019. PMID: 31243771.
11. Tetzlaff MT, Tang S, Duke T, Grabell DA, Cabanillas ME, Zuo Z, Yao JC, Nagarajan P, Aung PP, Torres-Cabala CA, Duvic M, Prieto VG, Huen A, Curry JL. Lichenoid dermatitis from immune checkpoint inhibitor therapy: An immune-related adverse event with mycosis-fungoides-like morphologic and molecular features. J Cutan Pathol 46(11):872-877, 2019. e-Pub 2019. PMID: 31254410.
12. Zuo Z, Li S, Xu J, You MJ, Khoury JD, Yin CC. Philadelphia-Negative Myeloproliferative Neoplasms: Laboratory Workup in the Era of Next-Generation Sequencing. Curr Hematol Malig Rep 14(5):376-385, 2019. PMID: 31388824.
13. Sakhdari A, Ok CY, Patel KP, Kanagal-Shamanna R, Yin CC, Zuo Z, Hu S, Routbort MJ, Luthra R, Medeiros LJ, Khoury JD, Loghavi S. TP53 mutations are common in mantle cell lymphoma, including the indolent leukemic non-nodal variant. Ann Diagn Pathol 41:38-42, 2019. e-Pub 2019. PMID: 31132650.
14. Quesada AE, Routbort MJ, DiNardo CD, Bueso-Ramos CE, Kanagal-Shamanna R, Khoury JD, Thakral B, Zuo Z, Yin CC, Loghavi S, Ok CY, Wang SA, Tang Z, Bannon SA, Benton CB, Garcia-Manero G, Kantarjian H, Luthra R, Medeiros LJ, Patel KP. DDX41 mutations in myeloid neoplasms are associated with male gender, TP53 mutations and high-risk disease. Am J Hematol 94(7):757-766, 2019. e-Pub 2019. PMID: 30963592.
15. Hu B, Patel KP, Chen HC, Wang X, Wang F, Luthra R, Routbort MJ, Kanagal-Shamanna R, Medeiros LJ, Yin CC, Zuo Z, Ok CY, Loghavi S, Tang G, Tambaro FP, Thompson P, Burger J, Jain N, Ferrajoli A, Bose P, Estrov Z, Keating MJ, Wierda WG. Routine sequencing in CLL has prognostic implications and provides new insight into pathogenesis and targeted treatments. Br J Haematol 185(5):852-864, 2019. e-Pub 2019. PMID: 30924136.
16. Swaminathan M, Patel KP, Huynh-Lu J, Tang G, Zuo Z, Miranda R, Verstovsek S. Unique Case of Myeloproliferative Neoplasm with Two Rare Clonal Abnormalities: Rare JAK2 Exon 12 Mutation and Rare e14a3 (b3a3) BCR/ABL Fusion Transcript. Acta Haematol 141(1):23-27, 2019. e-Pub 2018. PMID: 30463063.
17. Patel KP, Ruiz-Cordero R, Chen W, Routbort MJ, Floyd K, Rodriguez S, Galbincea J, Barkoh BA, Hatfield D, Khogeer H, Kanagal-Shamanna R, Yin CC, Zuo Z, Loghavi S, Ok CY, DiNardo CD, Luthra R, Medeiros LJ. Ultra-Rapid Reporting of GENomic Targets (URGENTseq): Clinical Next-Generation Sequencing Results within 48 Hours of Sample Collection. J Mol Diagn 21(1):89-98, 2019. PMID: 30577887.
18. Jain P, Kanagal-Shamanna R, Konoplev S, Zuo Z, Estrov Z. Biclonal IGHV-4-34 hairy cell leukemia variant and CLL - successful treatment with ibrutinib and venetoclax. Am J Hematol 93(12):1568-1569, 2018. e-Pub 2018. PMID: 30152528.
19. Loghavi S, Sui D, Wei P, Garcia-Manero G, Pierce S, Routbort MJ, Jabbour EJ, Pemmaraju N, Kanagal-Shamanna R, Gur HD, Hu S, Zuo Z, Medeiros LJ, Kantarjian HM, Khoury JD. Validation of the 2017 revision of the WHO chronic myelomonocytic leukemia categories. Blood Adv 2(15):1807-1816, 2018. PMID: 30054307.
20. Ok CY, Loghavi S, Sui D, Wei P, Kanagal-Shamanna R, Yin CC, Zuo Z, Routbort MJ, Tang G, Tang Z, Jorgensen JL, Luthra R, Ravandi F, Kantarjian HM, DiNardo CD, Medeiros LJ, Wang SA, Patel KP. Persistent IDH1/2 mutation in remission can predict relapse in patients with acute myeloid leukemia. Haematologica. e-Pub 2018. PMID: 30171025.
21. Jabbar KJ, Yin CC, Bueso-Ramos CE, Luthra R, Medeiros LJ, Zuo Z. Higher body mass index is associated with better survival in patients with myelodysplastic syndromes. Leuk Res 71:63-66, 2018.
22. Ding Q, Wang Y, Zuo Z, Gong Y, Krishnamurthy S, Li CW, Lai YJ, Wei W, Wang J, Manyam GC, Diao L, Zhang X, Lin F, Symmans WF, Sun L, Liu CG, Liu X, Debeb BG, Ueno NT, Harano K, Alvarez RH, Wu Y, Cristofanilli M, Huo L. Decreased expression of microRNA-26b in locally advanced and inflammatory breast cancer. Hum Pathol 77:121-129, 2018. e-Pub 2018. PMID: 29689244.
23. Margolskee E, Mikita G, Rea B, Bagg A, Zuo Z, Sun Y, Goswami M, Wang SA, Oak J, Arber DA, Allen MB, George TI, Rogers HJ, Hsi E, Hasserjian RP, Orazi A. A reevaluation of erythroid predominance in Acute Myeloid Leukemia using the updated WHO 2016 Criteria. Mod Pathol 31(6):873-880, 2018. e-Pub 2018. PMID: 29403082.
24. Ohanian M, Rozovski U, Kanagal-Shamanna R, Abruzzo LV, Loghavi S, Kadia T, Futreal A, Bhalla K, Zuo Z, Huh YO, Post SM, Ruvolo P, Garcia-Manero G, Andreeff M, Kornblau S, Borthakur G, Hu P, Medeiros LJ, Takahashi K, Hornbaker MJ, Zhang J, Nogueras-González GM, Huang X, Verstovsek S, Estrov Z, Pierce S, Ravandi F, Kantarjian HM, Bueso-Ramos CE, Cortes JE. MYC protein expression is an important prognostic factor in acute myeloid leukemia. Leuk Lymphoma:1-12. e-Pub 2018. PMID: 29741984.
25. Quesada AE, Hu Z, Routbort MJ, Patel KP, Luthra R, Loghavi S, Zuo Z, Yin CC, Kanagal-Shamanna R, Wang SA, Jorgensen JL, Medeiros LJ, Ok CY. Mixed phenotype acute leukemia contains heterogeneous genetic mutations by next-generation sequencing. Oncotarget 9(9):8441-8449, 2018. e-Pub 2018. PMID: 29492206.
26. Agbay RLMC, Loghavi S, Zuo Z, Fayad L, Dabaja B, Medeiros LJ, Khoury JD. Bone Marrow Involvement in Patients With Nodular Lymphocyte Predominant Hodgkin Lymphoma. Am J Surg Pathol. e-Pub 2018. PMID: 29309302.
27. Quesada AE, Medeiros LJ, Desai PA, Lin P, Westin JR, Hawsawi HM, Wei P, Tang G, Seegmiller AC, Reddy NM, Yin CC, Wang W, Xu J, Miranda RN, Zuo Z, Li S. Increased MYC copy number is an independent prognostic factor in patients with diffuse large B-cell lymphoma. Mod Pathol 30(12):1688-1697, 2017. e-Pub 2017. PMID: 28776574.
28. Kanagal-Shamanna R, Hidalgo Lopez JE, Milton DR, Kim HR, Zhao C, Zuo Z, Janania Martinez M, Stingo F, Lee J, Luthra R, Jabbour EJ, Garcia-Manero G, Medeiros LJ, Bueso-Ramos CE. Validation of the 2016 revisions to the WHO classification in lower-risk myelodysplastic syndrome. Am J Hematol 92(8):E168-E171, 2017. e-Pub 2017. PMID: 28456995.
29. Hidalgo-López JE, Kanagal-Shamanna R, Medeiros LJ, Estrov Z, Yin CC, Verstovsek S, Konoplev S, Jorgensen JL, Mohammad MM, Miranda RN, Zhao C, Lee J, Zuo Z, Bueso-Ramos CE. Morphologic and Molecular Characteristics of De Novo AML With JAK2 V617F Mutation. J Natl Compr Canc Netw 15(6):790-796, 2017. PMID: 28596259.
30. Chen Z, Shao C, Wang W, Zuo Z, Mou X, Hu SJ, DiGiuseppe JA, Zu Y, Medeiros LJ, Hu S. Cytogenetic landscape and impact in blast phase of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Leukemia 31(3):585-592, 2017. e-Pub 2016. PMID: 27560111.
31. Wang SA, Patel KP, Pozdnyakova O, Peng J, Zuo Z, Dal Cin P, Steensma DP, Hasserjian RP. Acute erythroid leukemia with <20% bone marrow blasts is clinically and biologically similar to myelodysplastic syndrome with excess blasts. Mod Pathol 29(10):1221-31, 2016. PMID: 27443511.
32. Alayed K, Medeiros LJ, Patel KP, Zuo Z, Li S, Verma S, Galbincea J, Cason RC, Luthra R, Yin CC. BRAF and MAP2K1 mutations in Langerhans cell histiocytosis: a study of 50 cases. Hum Pathol 52:61-7, 2016. e-Pub 2016. PMID: 26980021.
33. Jain P, Tang G, Huh YO, Yin CC, Zuo Z, Pemmaraju N, Estrov Z, Daver N.. Philadelphia - positive dimorphic blasts in mixed-phenotype acute leukemia with TET2 mutation. Am J Hematol 91(6):647-8, 2016. e-Pub 2016. PMID: 26799924.
34. Li S, Saksena A, Desai P, Xu J, Zuo Z, Lin P, Tang G, Yin CC, Seegmiller A, Jorgensen JL, Miranda RN, Reddy NM, Bueso-Ramos C, Medeiros LJ.. Prognostic impact of history of follicular lymphoma, induction regimen and stem cell transplant in patients with MYC/BCL2 double hit lymphoma. Oncotarget 7(25):38122-38132, 2016. e-Pub 2016. PMID: 27203548.
35. Ouyang J, Goswami M, Peng J, Zuo Z, Daver N, Borthakur G, Tang G, Medeiros LJ, Jorgensen JL, Ravandi F, Wang SA.. Comparison of Multiparameter Flow Cytometry Immunophenotypic Analysis and Quantitative RT-PCR for the Detection of Minimal Residual Disease of Core Binding Factor Acute Myeloid Leukemia. Am J Clin Pathol 145(6):769-77, 2016. e-Pub 2016. PMID: 27298396.
36. Huo L, Wang Y, Gong Y, Krishnamurthy S, Wang J, Diao L, Liu CG, Liu X, Lin F, Symmans WF, Wei W, Zhang X, Sun L, Alvarez RH, Ueno NT, Fouad TM, Harano K, Debeb BG, Wu Y, Reuben J, Cristofanilli M, Zuo Z.. MicroRNA expression profiling identifies decreased expression of miR-205 in inflammatory breast cancer. Mod Pathol 29(4):330-46, 2016. e-Pub 2016. PMID: 26916073.
37. Jain N, Lamb AE, O'Brien S, Ravandi F, Konopleva M, Jabbour E, Zuo Z, Jorgensen J, Lin P, Pierce S, Thomas D, Rytting M, Borthakur G, Kadia T, Cortes J, Kantarjian HM, Khoury JD.. Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in adolescents and adults: a high-risk subtype. Blood 127(15):1863-9, 2016. e-Pub 2016. PMID: 26747249.
38. Zhou Y, Kanagal-Shamanna R, Zuo Z, Tang G, Medeiros LJ, Bueso-Ramos CE. Advances in B-lymphoblastic leukemia: cytogenetic and genomic lesions. Ann Diagn Pathol 23:43-50, 2016. PMID: 27130145.
39. Lou Y, Pecot CV, Tran HT, DeVito VJ, Tang XM, Heymach J, Luthra R, Wistuba II, Zuo Z, Tsao AS. Germline mutation of T790M and dual/multiple EGFR mutations in caucasian patients with lung adenocarcinoma. Clin Lung Cancer 17(2):e5-e11. e-Pub 2016. PMID: 26700910.
40. Kanagal-Shamanna R, Luthra R, Yin CC, Patel KP, Takahashi K, Lu X, Lee J, Zhao C, Stingo F, Zuo Z, Routbort MJ, Singh RR, Fox P, Ravandi F, Garcia-Manero G, Medeiros LJ, Bueso-Ramos CE.. Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS. Oncotarget. e-Pub 2016. PMID: 26883102.
41. Peng J, Zuo Z, Fu B, Oki Y, Tang G, Goswami M, Priyanka P, Muzzafar T, Medeiros LJ, Luthra R, Wang SA. Chronic myelomonocytic leukemia with nucleophosmin (NPM1) mutation. European Journal of Haematology 96(1):65-71, 2016. e-Pub 2015. PMID: 25809997.
42. Sevcikova K, Zuo Z, Garcia-Manero G, Alvarez R, Kantarjian HM, Mego M, Albarracin C, Tang G, Strom SS, Medeiros LJ, Hortobagyi GN, Reuben JM, Khoury JD. Comprehensive analysis of factors impacting risks and outcomes of therapy-related myeloid neoplasms following breast cancer treatment. Leukemia 30(1):242-7, 2016. e-Pub 2015. PMID: 25975189.
43. Zuo Z, Jabbar KJ. COLD-PCR: Applications and Advantages. Methods Mol Biol(1392):17-25, 2016. PMID: 26843042.
44. Loghavi S, Al-Ibrahimi A, Zuo Z, Garcia-Manero G, Yabe M, Wang SA, Kantarjian HM, Yin CC, Miranda RN, Luthra R, Medeiros LJ, Bueso-Ramos CE, Khoury JD. p53 overexpression is an adverse prognostic factor in myelodysplastic syndromes with fibrosis independent of cytognenetics and bone marrow blast count. British Journal of Haematology 171(1):91-9, 2015. PMID: 26123119.
45. Loghavi S, Aladily TN, Alayed K, Zuo Z, Ng SB, Tang G, Hu S, Yin CC, Mirande RN, Medeiros LJ, Khoury JD. Stage, age, and EBV status impact outcomes of plasmablastic lymphoma patients: a clinicopathologic analysis of 61 patients. Journal of Hematology & Oncology 8(1):65-76, 2015. PMID: 26055271.
46. Zenali M, deKay J, Liu Z, Hamilton S, Zuo Z, Lu X, Bakkar R, Mills G, Broaddus R. Retrospective Review of MET Gene Mutations. Oncoscience 2(5):533-541, 2015. PMID: 26097886.
47. Mehrotra M, Patel KP, Chen T, Miranda RN, Wang Y, Zuo Z, Muddasani R, Mishra BM, Abraham R, Luthra R, Lu R. Genomic and clinicopathologic features of primary myelofibrosis with isolated 13q deletion. Clinical Lymphoma, Myeloma & Leukemia. e-Pub 2015. PMID: 26027540.
48. Mego M, Zuo Z, Gao H, Cohen EN, Giordano A, Tin S, Anfossi S, Jackson S, Woodward W, Ueno NT, Valero V, Alvarez RH, Hortobagyi GN, Khoury JD, Cristofanilli M, ReubenJM. Circulating tumor cells are linked to plasma D-dimer levels in patients with metastatic breast cancer. Thrombosis and Haemostasis 113(3):593-8, 2015. e-Pub 2014. PMID: 25373787.
49. Li Y, Hu S, Zuo Z, Li S, Lin P, Konoplev S, Wang Z, Young K, Medeiros LJ, Yin CC. CD5-positive follicular lymphoma: a clinicopathologic study of 88 cases. Mod Pathol. e-Pub 2015. PMID: 25743023.
50. Yin CC, Jain N, Mehrotra M, Zhang J, Protopopov A, Zuo Z, Pemmaraju N, DiNardo C, Hirsch-Ginsberg C, Wang SA, Medeiros LJ, Chin L, Patel KP, Ranvandi F, Futreal A, Bueso-Ramos CE. Identification of a novel fusion gene, IRF2BP2-RARA, in acute promyelocytic leukemia. Journal of the National Comprehensive Cancer Network 13(1):19-22, 2015. PMID: 25583766.
51. Loghavi S, Zuo Z, Patel KP, Singh R, Zhang L, Medeiros LJ, Stingo F, Routbort M, Cortes J, Ravandi F, Kantarjian HM, Bueso-Ramos C, Luthra R, Khoury JD. Clinical features of De Novo acute myeloid leukemia with concurrent DNMT3A , FLT3 and NPM1 mutations. Journal of Hematology and Oncology 7(1):74, 2014. PMID: 25281355.
52. Zuo Z, Maiti S, Hu S, Loghavi S, Calin GA, Garcia-Manero G, Kantarjian HM, Medeiros LJ, Cooper LJN, Bueso-Ramos C,. Plasma Circulating microRNA Profiling for Prognostic Biomarkers in Cytogenetically Normal Myelodysplastic Syndromes. Mod Pathol 28(3):373-82. e-Pub 2014. PMID: 25216221.
53. Wang S, Medeiros LJ, Xu-Monette ZY, Zhang S, O'Malley DP, Orazi A, Zuo Z, Bueso-Ramos CE, Yin CC, Liu Z, Miranda RN, Young KH. Epstein-Barr virus-positive nodular lymphocyte predominant Hodgkin lymphoma. Ann Diagn Pathol 18(4):203–209, 2014. e-Pub 2014. PMID: 24852241.
54. Portier BP, Luthra R, Singh R, Routbort M, Handal B, Reddy N, Barkoh BA, Zuo Z, Medeiros LJ, Aldape K, Patel KP. Quantitative Assessment of Mutant Allele Burden in Solid Tumors by Semiconductor Based Next Generation Sequencing. Am J Clin Pathol 141(4):559-572, 2014. PMID: 24619758.
55. Ok CY, Hasserjian RP, Fox PS, Stingo F, Zuo Z, Young KH, Patel K, Medeiros LJ, Garcia-Manero G, Wang SA. Application of the International Prognostic Scoring System-Revised in therapy-related myelodysplastic syndromes and oligoblastic acute myeloid leukemia. Leukemia 28(1):185-9, 2014. e-Pub 2013.
56. Hoehn D, Lu G, Konoplev S, Zhou Y, Bueso-Ramos CE, Zuo Z, Hsu B, Medeiros LJ, Yin CC. t(15;17)(q24.1;q21.2)/PML-RARA in blast phase of chronic myelogenous leukemia: a unique clonal evolution. J Hematopathol 6(4):187-193, 2013. e-Pub 2012.
57. Chakhachiro ZI, Zuo Z, Aladily TN, Kantarjian HM, Cortes JE, Alayed K, Nguyen MH, Medeiros LJ, Bueso-Ramos C. CD105 (Endoglin) Is Highly Overexpressed in a Subset of Cases of Acute Myeloid Leukemias. Am J Clin Pathol 140(3):370-378, 2013.
58. Fu B, Wang Z, Li X, Wang SA, Zuo Z. Detection of BRAF V600E mutation in langerhans cell histiocytosis using high-resolution melting analysis in decalcified, paraffin-embedded tissue. J Leuk 1:101, 2013.
59. Konoplev S, Yin CC, Kornblau SM, Kantarjian HM, Konopleva M, Andreeff M, Lu G, Zuo Z, Luthra R, Medeiros LJ, Bueso-Ramos CE. Molecular characterization of de novo Ph+ Acute Myeloid Leukemia. Leuk Lymphoma 54(1):138-44, 2013. e-Pub 2012.
60. Li S, Feng X, Li T, Zhang S, Zuo Z, Lin P, Konoplev S, Bueso-Ramos CE, Vega-Vazquez F, Medeiros LJ, Yin CC. Extranodal NK/T-Cell lymphoma, nasal type: A report of 73 cases at MD Anderson Cancer Center. Am J Surg Pathol 37(1):14-23, 2013. PMID: 23232851.
61. Warren M, LUthra R, Yin CC, Ravandi F, Cortes JE, Kantarjian HM, Medeiros LJ, Zuo Z. Clinical impact of change of FLT3 mutation status in acute myeloid leukemia patients. Mod Pathol 25(10):1405-12, 2012. e-Pub 2012.
62. Zuo Z, Medeiros LJ, Chen Z, Liu D, Bueso-Ramos CE, Luthra R, Wang SA. Acute myeloid leukemia (AML) with erythroid predominance exhibits clinical and molecular characteristics that differ from other types of AML. PLoS ONE 7(7):e41485, 2012. e-Pub 2012.
63. Tang G, Zuo Z, Thomas DA, Lin P, Liu D, Hu Y, Kantarjian HM, Bueso-Ramos C, Medeiros LJ, Wang SA. B-Acute lymphoblastic Leukemia Occurring in Patients with a History of Prior Malignancies: Is it Therapy-related?. Haematologica 97(6):919-25, 2012. e-Pub 2011. PMID: 22207681.
64. Li C, Thompson MA, Tamayo AT, Zuo Z, Lee J, Vega F, Ford RJ, Pham LV.. Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma. Oncotarget 3(3):314-26, 2012. e-Pub 2012.
65. Bai B, Zuo Z, Cheong SH, Vo B, Harper E, Lovshe D, Yang S, Yin CC. Novel chromosomal aberration as evidence of clonal evolution in a case of relapsed acute myeloid leukemia. N Am J Med Sci 5(1):48-50, 2012.
66. Barakat FH, Luthra R, Barkoh BA, Hai S, Jamil W, Herrman S, Bhakta Y, Chen S, Medeiros LJ, Zuo Z. Detection of nucleophosmin 1 mutations by quantitative real-time polymerase chain reaction versus capillary electrophoresis: a comparative study. Arch Pathol Lab Med 135(8):994-1000, 2011. PMID: 21809990.
67. Zuo Z, Goel S, Carter E. Association of cervical cytology and HPV DNA status during pregnancy with placental abnormalities and preterm birth. Am J Clin Pathol 136(2):260-5, 2011. PMID: 21757599.
68. Zuo Z, Calin GA, de Paula HM, Medeiros LJ, Fernandez MH, Shimizu M, Garcia-Manero G, Bueso-Ramos CE. Circulating microRNAs Let-7a and miR-16 predict progression-free survival and overall survival in patients with myelodysplastic syndrome. Blood 118(2):413-5, 2011. e-Pub 2011. PMID: 21602527.
69. Alseraye FM, Zuo Z, Bueso-Ramos CE, Wang S, Medeiros LJ, Lu G.. Trisomy 11 as an isolated abnormality in acute myeloid leukemia is associated with unfavorable prognosis but not with an NPM1 or KIT mutation. Int J Clin Exp Pathol 4(4):371-7, 2011.
70. Bains A, Luthra R, Medeiros LJ, Zuo Z. FLT3 and NPM1 mutations in myelodysplastic syndromes: frequency and potential value for predicting progression to acute myeloid leukemia. Am J Clin Pathol 135(1):62-69, 2011.
71. Zuo Z, Jones D, Yao H, Thomas DA, O'Brien S, Ravandi F, Kantarjian HM, Abruzzo LV, Medeiros LJ, Chen SS, Luthra R. A pathway-based gene signature correlates with therapeutic response in patients with adult philadelphia-chromosome positive acute lymphoblastic leukemia. Mod Pathol 23(11):1524-34, 2010. e-Pub 2010.
72. Zuo Z, Polski JM, Kasyan A, Medeiros LJ. Acute erythroid leukemia. Arch Pathol Lab Med 134(9):1261-1270, 2010. PMID: 20807044.
73. Chandra P, Luthra R, Zuo Z, Yao H, Ravandi F, Reddy N, Garcia-Manero G, Kantarjian H, Jones D. Acute myeloid leukemia with t(9;11)(p21-22;q23): common properties of dysregulated ras pathway signaling and genomic progression characterize de novo and therapy-related cases. Am J Clin Pathol 133(5):686-93, 2010. PMID: 20395514.
74. Kasyan A, Medeiros LJ, Zuo Z, Santos FP, Ravandi-Kashani F, Miranda R, Vadhan-Raj S, Koeppen H, Bueso-Ramos CE. Acute erythroid leukemia as defined in the World Health Organization classification is a rare and pathogenetically heterogeneous disease. Mod Pathol 23(8):1113-26. e-Pub 2010. PMID: 20473273.
75. Zuo Z*, Hasserjian RP* (*equal contributors), Garcia C, Tang G, Kasyan A, Luthra R, Abruzzo LV, Kantarjian HM, Medeiros LJ, Wang SA. Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification. Blood 115(10):1985-92, 2010. e-Pub 2009. PMID: 20040759.
76. Zuo Z, Chen SS, Chandra PK, Galbincea JM, Soape M, Doan S, Barkoh BA, Koeppen H, Medeiros LJ, Luthra R. Application of COLD-PCR for improved detection of KRAS mutations in clinical samples. Mod Pathol 22(8):1023-31, 2009. e-Pub 2009. PMID: 19430420.
77. Chandra P, Plaza JA, Zuo Z, Diwan AH, Koeppen H, Duvic M, Medeiros LJ, Prieto VG. Clusterin expression correlates with stage and presence of large cells in mycosis fungoides. Am J Clin Pathol 131(4):511-5, 2009. PMID: 19289586.
78. Zuo Z, Chandra P, Wen YH, Koeppen H. Molecular diagnostics of acute myeloid leukemia. Diagn Histopathol 15(11):531-9, 2009.
79. Zuo Z, Jimenez X, Witte L, Zhu Z. An efficient route to the production of an IgG-like bispecific antibody. Protein Eng 13(5):361-7, 2000. PMID: 10835110.
80. Zuo Z, Urban G, Scammell JG, Dean NM, McLean TK, Aragon I, Honkanen RE. Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest. Biochemistry 38(28):8849-57, 1999. PMID: 10413457.
81. Wang L, Bhattacharjee A, Zuo Z, Hu F, Honkanen RE, Berggren PO, Li M. A low voltage-activated Ca2+ current mediates cytokine-induced pancreatic beta-cell death. Endocrinology 140(3):1200-4, 1999. PMID: 10067844.
82. Cheng A, Balczon R, Zuo Z, Koons JS, Walsh AH, Honkanen RE. Fostriecin-mediated G2-M-phase growth arrest correlates with abnormal centrosome replication, the formation of aberrant mitotic spindles, and the inhibition of serine/threonine protein phosphatase activity. Cancer Res 58(16):3611-9, 1998. PMID: 9721869.
83. Zuo Z, Dean NM, Honkanen RE. Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest. J Biol Chem 273(20):12250-8, 1998. PMID: 9575175.
84. Zuo Z, Mahesh VB, Zamorano PL, Brann DW. Decreased gonadotropin-releasing hormone neurosecretory response to glutamate agonists in middle-aged female rats on proestrus afternoon: a possible role in reproductive aging?. Endocrinology 137(6):2334-8, 1996. PMID: 8641183.
85. Shi SQ, Zuo Z, Zuo XC. [Ripening effect of mylis and tiluoan on the uterine cervix in pregnant rats]. Zhonghua Fu Chan Ke Za Zhi 29(4):224-6, 253-4, 1994. PMID: 8082446.
86. Zuo XC, Shi SQ, Zuo Z. Ripening effects of mylis and dehydroepiandrosterone on uterine cervix of pregnant rats. Acta Academiae Medicinae Sinicae 14(2):136, 1992.
87. Zuo Z, Li SC. A review of Chinese and Western medical research on free radical related diseases and aging. Beijing Journal of Traditional Chinese Medicine 1:58-60, 1991.
88. Wang Y, Quesada AE, Zuo Z, Medeiros LJ, Yin CC, Shaoying Li, Jie Xu, Gautam Borthakur, Yisheng Li, Chao Yang, Yasmin Abaza, Juehua Gao, Xinyan Lu, M. James You, Yizhuo Zhang *, Pei Lin *. The Impact of Mutation of Myelodysplasia-Related Genes in De Novo Acute Myeloid Leukemia -Carrying NPM1 Mutation. Cancers.

Editorials

1. Luthra R, Zuo Z. COLD-PCR finds hot application in mutation analysis. Clin Chem 55(12):2077-8, 2009. PMID: 19833831.

Abstracts

1. Jabbar KJ, Yin CC, Bueso-Ramos CE, Luthra R, Medeiros LJ, Zuo Z. Higher body mass index is associated with better survival in patients with myelodysplastic syndromes. UT MD Anderson Cancer Center Trainee Research Day, 2014.
2. Loghavi S, Zuo Z, Patel KP, Singh R, Zhang L, Medeiros LJ, Stingo F, Routbort M, Cortes J, Ravandi F, Kantarjian HM, Bueso-Ramos C, Luthra R, Khoury JD. DNMT3A Mutations Exert A Dominant Adverse Effect In De Novo Acute Myeloid Leukemia With Concurrent FLT3 And NPM1 Mutations. Mod Pathol 27:359A (#1478), 2014.
3. Loghavi S, Bueso-Ramos CE, Maiti SN, Hu S, Calin GA, Garcia-Manero G, Kantarjian HM, Medeiros J, Cooper L, Zuo Z. Diagnostic and Prognostic Utility of Plasma microRNA Signatures in Patients with Myelodysplastic Syndromes. Mod Pathol 27(suppl 2):359A (#1479), 2014.
4. Ok CY, Zuo Z, Garcia-Manero G, Medeiros LJ, Wang SA. Implications of Using the Revised International Prognostic Scoring System (IPSS-R) for Patients with Therapy-Related Neoplasms. Mod Pathol 26:354A (#1840), 2013.
5. Zenali M, Liu Z, Zuo Z, Broaddus R. cMET Mutations, Co-Mutations, and Survival Outcome. Mod Pathol 26(suppl 2):447A (#1861), 2013.
6. Portier BP, Luthra R, Singh R, Routbort M, Handal B, Reddy N, Barkoh BA, Zuo Z, Medeiros LJ, Aldape K, Patel KP. Quantitative Assessment of Mutant Allele Burden in Solid Tumors by Semiconductor Based Next Generation Sequencing. Mod Pathol 26(suppl 2):499A (#2081), 2013.
7. Zuo Z, Bueso-Ramos CE, Yin CC, Medeiros LJ. Acute myeloid leukemia with monocytic differentiation. Society for Hematopathology/European Association for Haematopathology 2013 Workshop:186, 2013.
8. Alayed K, Patel K, Zuo Z, Verma S, Galbincea J, Cason RC, Luthra R, Medeiros LJ, Yin CC. BRAF mutation occurs more frequently in pulmonary Langerhans cell histiocytosis and in younger patients. J Mol Diagn 15(6):858-859, 2013.
9. Wang XI, Patel K, Lin P, Zuo Z, Bueso-Ramos CE, Luthra R, Medeiros LJ, Yin CC. Clinicopathologic and molecular genetic features of de novo myeloid sarcoma. Mod Pathol 26(suppl 2):365A, 2013.
10. Wang XI, Patel K, Routbort M, Zuo Z, Lin P, Bueso-Ramos CE, Luthra R, Medeiros LJ, Yin CC. De novo myeloid sarcoma with subsequent AML development, diploid karyotype and mutations in IDH2, TP53 and GNAS. Society for Hematopathology/European Association for Haematopathology 2013 Workshop:357, 2013.
11. Yabe M, Bai B, Wang XI, Zuo Z, Yin CC. Novel Chromosomal Aberration, t(2;16)(p21;p11.2),t(11;14)(p13;p11.2), as evidence of clonal evolution in a case of relapsed acute myeloid leukemia. Society for Hematopathology/European Association for Haematopathology 2013 Workshop:318, 2013.
12. S. Kim, N. Gonzalez, R. Luthra, K. Aldape, Z. Zuo, P. Liu, D. Barron, K. B. Kim. Frequency and clinical characteristics of c-MET mutation in malignant melanoma. Cancer Research 72(8 Supplement):4588, 2012.
13. Kanagal-Shamana R, Yin CC, Muddasani R, Luthra R, Cortes J, Zuo Z, Chen SS, Hu S, Abruzzo LV, Miranda RN, Medeiros LJ, Lu G. Acute myeloid leukemias with translocations involving 4q12/PDGFRA: Frequent involvement of ETV6. Mod Pathol 25(suppl 2):346A, 2012.
14. Warren M, luthra R, Yin CC, Ravandi F, Medeiros LJ, Zuo Z. Clinical impact of change of FLT3 mutation status in acute myeloid leukemia patients. Mod Pathol 25(suppl 2):379A, 2012.
15. Tang G, Zuo Z, Hu Y, Lin P, Medeiros LJ, Wang SA. B-Lymphoblastic Leukemia/Lymphoma Occurring in Patients with a History of Malignancy: Is It Therapy-Related?. Mod Pathol 25(suppl 2):375A, 2012.
16. Chakhachiro ZI, Zuo Z, Kantarjian HM, Cortes JE, Alayed K, Nguyen MH, Vadhan-Raj S, Medeiros LJ, Bueso-Ramos C. Endoglin (CD105) Is Strongly Overexpressed in AML with t(15;17)/ PML-RARA and Is Signifi cantly Associated with IDH2 Mutation, but Is Not Expressed in Bone Marrow Endothelial Cells. Mod Pathol 25(suppl 2):327A, 2012.
17. Konoplev S, Yin C, Kornblau SM, Kantarjian HM, Konopleva M, Andreeff M, Lu G, Zuo Z, Luthra R, Medeiros LJ, Bueso-Ramos CE. NPM1 Mutation Occurs in a Subset of Ph+ AML Suggesting that this Entity is Distinct from CML in Myeloid Blast Phase. Journal of Molecular Diagnostics 13(6):731, 2011.
18. Zuo Z, Greaves WO, Luthra R, Sargent R, Chen SS, Galbincea J, Medeiros L, Yin C. KIT Mutation Is Rare in Acute Myeloid Leukemias, Almost Always Involves Exon 17, and Occurs Predominantly in AML with t(8;21)(q22;q22). Journal of Molecular Diagnostics 13(6):729, 2011.
19. Bartley AN, Luthra R, Yao H, Zuo Z, Medeiros J, Patel KP. Distinct Molecular Characteristics of FLT3 Mutations Involving Multiple Internal Tandem Duplications. Journal of Molecular Diagnostics 13(6):726, 2011.
20. Barkoh BA, Patel R, Manekia J, Bartley AN, Zuo Z, Patel K, Luthra R. Comparison of SNaPshot® Fluorescent Capillary Electrophoresis and Sequenom® MassARRAY Based Platforms for Multiplex Solid Tumor Mutation Screening. Journal of Molecular Diagnostics 13(6):775, 2011.
21. Li S, Zuo Z, Bueso-Ramos CE, Yin CC. FLT3 mutation in a case of T-lymphoblastic leukemia with aberrant CD117 expression. 2011 ASCP Annual Meeting/WASPaLM World Congress, Las Vegas, NV, 2011.
22. Hoehn D, Zhou Y, bueso-Ramos CE, Lun G, Zuo Z, Konoplev S, Hsu B, Medeiros LJ, Yin CC. t(15;17)(q22;q21)/PML-RARA in blast phase of chronic myelogenous leukemia: a unique clonal evolution. 2011 ASCP Annual Meeting/WASPaLM World Congress, Las Vegas, NV, 2011.
23. George AM, Zuo Z, Hu P, Yin CC. Impact of numbers of FLT3 internal tandem duplication on clinicla outcome of patients with acute myeloid leukemia and diploid karyotype. UT MD Anderson Cancer Center Trainee Research Day, 2011.
24. Ma D, Luthra R, Chen SS, Yin CC, Sargent RL, Patel KP, Medeiros J, Zuo Z. RAS Mutational Analysis in 9334 Solid and Hematopoietic Malignancies. Modern Pathology 24(Suppl 1):394A (#1677), 2011.
25. Chen SS, Zuo Z, Luthra R, Lu G, Borthakur G, Wang S, Medeiros LJ, Yin CC. Double mutations of NRAS and KRAS in acute myeloid leukemia and myelodysplastic syndrome are associated with monocytic differentiation, multilineage dysplasia, increased myeloblasts and prior chemotherapy. Mod Pathol 24 (suppl 1):290A (#1235), 2011.
26. Chen SS, Zuo Z, Galbincea JM, Medeiros L, Luthra R. False Positive vs True-Positive Results of EGFR Mutation Analysis Using Formalin Fixed Paraffin Embedded Tissue. Journal of Molecular Diagnostics 12(6):920-921, 2010.
27. Barakat FH, Luthra R, Barkoh BA, Hai S, Jamil W, Herrman S, Bhakta Y, Chen S, Medeiros LJ, Zuo Z. NPM1 Mutation Detection: A Comparative Study of Quantitative Real-Time PCR and Capillary Electrophoresis in 157 Clinical Samples. Modern Pathology 23(Suppl. 1):431A, 2010.
28. Chen SS, Luthra R, Medeiros LJ, Zuo Z. Molecular Profiles of EGFR and KRAS Mutations in Non-Small-Cell Lung Carcinoma: A Survey of 344 Cases. Modern Pathology 23(Suppl. 1):399A, 2010.
29. Bains A, Luthra R, Medeiros LJ, Zuo Z. Different Roles of NPM1 and FLT3 Mutations in Myelodysplastic Syndromes. Modern Pathology 23(Suppl. 1):286A, 2010.
30. Alseraye FM, Zuo Z, Bueso-Ramos CE, Medeiros LJ, Barakat, FH Lu G. Trisomy 11 as a Sole Abnormality in Acute Myeloid Leukmia and Myelodysplastic Syndrome has Unfavorable Prognosis but No Association with Mutations of Kit and RAS Genes. Modern Pathology 23(Suppl. 1):284A, 2010.
31. Boudreaux CW, Laurini JA, Zuo Z, Kahn AG. High Risk Human Papillomavirus (HPV) DNA Testing in SurePath Liquid Based Pap Test Specimens: Differences in Results among Pre and Peri-postmenopausal Women with Atypical Squamous Cells of Undetermined Significance (ASCUS). Cancer Cytopathology 117(5):389-390, 2009.
32. Zuo Z, Jones D, Yao H, Thomas DA, O'Brien S, Ravandi F, Kantarjian HM, Abruzzo LV, Medeiros LJ, Chen SS, Luthra R. A nine-gene predictor of therapy response in adult Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph+ ALL). Journal of Clinical Oncology 27(15), 2009.
33. Zuo Z, Soape M, Doan S, Chandra P, Galbincea J, Barkoh B, R Luthra. Application of COLD-PCR for Improved Detection of KRAS Mutations in Clinical Samples. Modern Pathology 22(Suppl. 1):391A, 2009.
34. Zuo Z, Kasyan A, Chandra P, Medeiros J, Koeppen H. Acute Erythroid Leukemias - Histologic, Cytogenetic and Molecular Characterization. Modern Pathology 22(Suppl. 1):293A, 2009.
35. Zuo Z, Goel S, Carter JE. Prepartum Cervical Cytologic Changes Correlated with Abnormal Placental Changes and Preterm Delivery. Modern Pathology 22(Suppl. 1):243A, 2009.
36. Chandra P, Zuo Z, Plaza JA, Koeppen H, Diwan AD, Medeiros J, Prieto VG. Clusterin Expression Correlates with Tumor Progression in Mycosis Fungoides. Modern Pathology 22(Suppl. 1):101A-102A, 2009.
37. Goel S, Kahn AG, Zuo Z, Patterson KV. Post-Mortem Diagnosis of Lymphoma: Report of Five Cases with Review of the Literature and Discussion of Specialized Diagnostic Techniques. Modern Pathology 22(Suppl. 1):6A, 2009.
38. Zuo Z, Laurini JA, Carter JE. Prevalence of sexually transmitted diseases and rate of coinfection: a study of 10,114 females from a university-based healthcare system. Arch Pathol Lab Med 132(9):1509-10, 2008.
39. Whithaus KC, Zuo Z, Manci EA. Negative estrogen and progesterone receptor immunohistochemistry in hepatoblastoma and positive estrogen receptor in adjacent normal hepatocytes. Arch Pathol Lab Med 132(9):1469-70, 2008.
40. Zuo Z, Boudreaux CW. Text Mining on Free-Text Based Anatomic Pathology Information Systems: A Front-End Data Integration Approach. Arch Pathol Lab Med 132(5):868, 2008.
41. Zuo Z, Kahn AG, Tucker JA. A data mining analysis of pathological findings in 11259 placentas. FASEB J 22:1123.22, 2008.
42. Martin SH, Kahn AG, Tucker JA, Zuo Z, Polski JM. Bone marrow talc granulomatosis. Arch Pathol Lab Med 131(9):1408, 2007.
43. Zuo Z, Manci E. An Analysis of Pediatric Autopsy Findings through Text Mining. Modern Pathology 20(Suppl. 2):10A, 2007.
44. Zuo Z, Polski JM. Myelodysplastic syndrome with clonal evolution into erythroleukemia. Arch Pathol Lab Med 130(2):1384, 2006.
45. Zuo Z, Boudreaux CW. Platform independent integration of pathology reports for data mining. Am J Clin Pathol 126(4):650, 2006.
46. Cho C, Kim K, Zuo Z. An application framework for predictive modeling of biological processes. Proceedings of ICSB2001: 2nd International Conference on Systems Biology, 2001.

Book Chapters

1. Zuo Z, Jabbar KJ. COLD-PCR: Applications and Advantages. In: Methods in Molecular Biology: Clinical Applications of PCR. Humana Press, 2014.
2. Jones D, Zuo Z and Chen S. Molecular diagnostics and cytogenetic testing. In: Experimental and Clinical Hematopathology. The Humana Press Inc, 2009.