Adegbenga O. Otun, DDS, FAAMP, FAAOM, FRCDC, FACP
Department of Head and Neck Surgery, Division of Surgery
About Dr. Adegbenga O. Otun
Dr. Adegbenga Otun is an assistant professor in the section of Oral Oncology and Maxillofacial Prosthodontics, Department of Head and Neck Surgery, at the University of Texas MD Anderson Cancer Center. In providing optimal patient care and improved treatment outcomes, he collaborates daily with colleagues in Head and Neck Surgery, Radiation and Medical Oncology, Plastic Surgery, Speech Pathology, Lymphoma, Myeloma, Leukemia, Breast and other medical disciplines.
Dr. Otun is a fellow of the American Academy of Maxillofacial Prosthetics (AAMP), member of the American College of Prosthodontics (ACP) and American Academy of Oral Medicine (AAOM). His clinical interests include implant and facial prosthetic rehabilitation and reduction of oral morbidities of cancer therapy. Area of Research concentration is understanding the shift in oral microbiome following head and neck radiation therapy.
Present Title & Affiliation
Primary Appointment
Assistant Professor, Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Assistant Professor, Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 1995 | University of Lagos, N/A, NG, BDS, DDS |
Postgraduate Training
| 2013-2014 | Clinical Fellowship, Advanced Education Program in Maxillofacial Prosthodontics and Oral Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2004-2007 | Clinical Residency, Prosthodontics, Eastman Institute of Oral Health University of Rochester, Rochester, New York |
Licenses & Certifications
| 2026 | Diplomate of the American Board of Prosthodontics |
| 2025 | The Royal College of Dentists of Canada Board Certified (FRCDC) |
| 2016 | Drug Enforcement Agency (DEA) - US Dept of Justice |
| 2016 | Health Care Provider: American Heart Association |
| 2015 | Department of Public Safety (DPS) - Texas Controlled Substance |
| 2013 | Board of Dentistry |
| 2011 | Texas State Board of Dental Examiners |
| 2010 | Washington Board of Dentistry |
Experience & Service
Administrative Appointments/Responsibilities
Adjunct Clinical Instructor, Dentistry, Detroit Mercy School of Dentistry, Detroit, MI, 2007 - 2007
Other Professional Positions
Member, Value Analysis Team (VAT), The University of Texas MD Anderson Cancer Center, Houston, TX, 2019
Consultant, Lakeshore Cancer Center, Lagos, Nigeria, 2014
Visiting Consultant, Choice Dental, Lagos, 2014 - 2015
Clinical Fellow, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2014
Prosthodontics, Allington Dental Practice, Dorset, 2012 - 2013
Prosthodontic Dentist, SMILE 360 Dental Specialists, Lagos, 2010 - 2012
Prosthodontist Restorative Dentist, Associated Dental Practices, London, 2010 - 2010
Prosthodontist, Dental Specialists, Milton Keynes, 2008 - 2009
Prosthodontic Resident, Eastman Dental Center, University of Rochester, Rochester, NY, 2004 - 2007
General Dentist, James Hull & Associates, Kent, 2003 - 2004
General Dentist, Whitecross Dental Care, London, 2001 - 2003
General Dentist, HO & Associates, London, 2001 - 2001
General Practice Residency, Lagos University Teaching Hospital, Lagos, 1996 - 1997
Extramural Institutional Committee Activities
Membership, Program Evaluation Committee - PEC, The University of Texas MD Anderson Cancer Center, 2024 - Present
Reviewer, ORN Physician Review Committee, The University of Texas MD Anderson Cancer Center, 2023
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2021. Oral Considerations in Patients Receiving Radiation Therapy, Targeted Therapies and Radioactive Iodine. Conference. Oral Pathology Symposium. Houston, TX, US.
- 2018. POSTER: A Case of Nasal NK T-Cell Lymphoma. Conference. Star of the South Dental Meeting. Houston, TX, US.
- 2017. POSTER: Palatal Augmentation Prosthesis Comparing Hollowing Techniques for Weight Reduction. Conference. Star of the South Dental Meeting. Houston, TX, US.
National Presentations
- 2025. Oral Morbidities of Radiotherapy Therapy and Pre-Radiation Evaluation. Conference. 2025 Oral Oncology Symposium. Houston, Texas, US.
- 2022. Oral Morbidities of Radiotherapy and Pre-Radiation Evaluation. Conference. 2022 Oral Oncology Symposium - Virtual. Houston, TX, US.
- 2022. Oral Complications of Radiotherapy/Chemotherapy and Its Management - Panel Session. Conference. 2022 Oral Oncology Symposium - Virtual. HOUSTON, TX, US.
- 2018. POSTER: The Effect of Zinc on Radiation Induced Dysgeusia: A Meta-Analysis. Invited. 65th Annual Meeting. Baltimore, MD, US.
- 2018. POSTER: The Effect of Zinc on Radiation Induced Dysgeusia: A Meta-Analysis. Invited. Annual Session. Baltimore, MD, US.
- 2017. Back-up Presenter. Conference. 2017 Oral Oncology Symposium. Houston, TX, US.
International Presentations
- 2017. POSTER: A Case of NKT Cell Lymphoma Nasal Type Presenting as Pain of Odontogenic origins. Invited. 4th Joint Conference. San Francisco, US.
- 2017. POSTER: Palatal Augmentation Prosthesis Comparing Hollowing Techniques for Weight Reduction. Invited. 4th Joint Conference. San Francisco, US.
Formal Peers
- 2014. Multidisciplinary Session Division of Oral Rehabilitation. Invited. Louisville, KY, US.
- 2014. Multidisciplinary Session Division of Oral Rehabilitation. Invited. Buffalo, NY, US.
- 2012. Full Mouth Reconstruction of the Debilitated Dentition. Invited, NG.
Grant & Contract Support
| Date: | 2021 - 2024 |
| Title: | Custom 3D Printed Stents for Head and Neck Radiation Therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1R01CA262572-01 |
| Title: | Investigation on the effect of Casting Techniques on the Dimension of Post and Cores and its Consequent Ease of Fit Clinically |
| Funding Source: | Greater New York Academy of Prosthodontics |
| Role: | PI |
Selected Publications
Peer-Reviewed Articles
- West, NA, Kamel, S, Wentzel, A, Kaffey, Z, Abdelaal, MA, Elisabeta Marai, G, Canahuate, GM, Zhang, X, Chen, MM, Wahid, K, Rigert, J, Brock, K, Chambers, MS, Otun, AO, Aponte Wesson, R, He, R, Naser, M, Hutcheson, KA, Mohamed, AS, van Dijk, L, Moreno, AC, Lai, SY, Fuller, C, Humbert-Vidan, L. Clinical and dosimetric dataset of time-to-event normal tissue complication probability for osteoradionecrosis. Scientific Data 13(1), 2026. e-Pub 2026. PMID: 41513675.
- Kaffey Z, Mirbahaeddin S, Wahid K, Kamel S, Vouffo M, Otun AO, Belal Z, Aponte Wesson RA, Carriere PP, Dede C, Maniakas A, Goepfert RP, Garden AS, Lee A, Choi KY, Christensen JM, Lincoln C, Manzar GS, Dudzinski SO, Thomas R, Mehrens H, Cardoso RC, Schellingerhout D, Watson E, Chen MM, Lai SY, Fuller CD, Moreno AC, Humbert-Vidan L. Radiographic classification of mandibular osteoradionecrosis: A blinded prospective multi-disciplinary interobserver diagnostic performance study. Radiother Oncol 208:110917, 2025. e-Pub 2025. PMID: 40320174.
- Kamel S, Humbert-Vidan L, Kaffey Z, Mirbahaeddin S, Abusaif A, Fuentes DTA, Wahid K, Dede C, Naser MA, He R, Moawad AW, Elsayes KM, Chen MM, Otun AO, Rigert J, Chambers MS, Hope A, Watson E, Brock KK, Hutcheson K, van Dijk L, Moreno AC, Lai SY, Fuller CD, Mohamed ASR. Computed tomography radiomics-based cross-sectional detection of mandibular osteoradionecrosis in head and neck cancer survivors. Oral Oncol 167:107337, 2025. e-Pub 2025. PMID: 40516152.
- Moreno AC, Watson EE, Humbert-Vidan L, Peterson DE, van Dijk LV, Urbano TG, Bosch LVD, Hope AJ, Katz MS, Hoebers FJP, Wesson RAA, Bates JE, Bossi P, Dayo AF, Dore M, Fregnani ER, Galloway TJ, Gelblum DY, Hanna IA, Henson CE, Kiat-Amnuay S, Korfage A, Lee NY, Lewis CM, Lynggaard CD, Makitie AA, Magalhaes M, Mowery YM, Munoz-Montplet C, Myers JN, Orlandi E, Patel J, Rigert JM, Saunders D, Schoenfeld JD, Selek U, Somay E, Takiar V, Thariat J, Verduijn GM, Villa A, West NS, Witjes MJH, Won AM, Wong ME, Yao CMKL, Young SW, Al-Eryani K, Barbon CEA, Buurman DJM, Dieleman FJ, Hofstede TM, Khan AA, Otun AO, Robinson JC, Hum L, Johansen J, Lalla R, Lin A, Patel V, Shaw RJ, Chambers MS, Ma D, Singh M, Yarom N, Mohamed ASR, Hutcheson KA, Lai SY, Fuller CD. International Expert-Based Consensus Definition, Classification Criteria, and Minimum Data Elements for Osteoradionecrosis of the Jaw: An Interdisciplinary Modified Delphi Study. Int J Radiat Oncol Biol Phys 122(2):341-354, 2025. e-Pub 2025. PMID: 39826846.
- Humbert-Vidan L, Kamel S, Wentzel A, Kaffey Z, Abdelaal M, Spier KB, West NA, Marai GE, Canahuate G, Zhang X, Chen MM, Wahid KA, Rigert J, Hosseinian S, Schaefer AJ, Brock KK, Chambers M, Otun AO, Aponte-Wesson R, Patel V, Hope A, Phan J, Garden AS, Frank SJ, Morrison WH, Spiotto MT, Rosenthal D, Lee A, He R, Naser MA, Watson E, Hutcheson KA, Mohamed ASR, Sandulache VC, van Dijk LV, Moreno AC, Urbano TG, Fuller CD, Lai SY. Externally validated digital decision support tool for time-to-osteoradionecrosis risk-stratification using right-censored multi-institutional observational cohorts. Radiother Oncol 207:110890, 2025. e-Pub 2025. PMID: 40222595.
- Tino R, Roach MA, Fuentes GD, Agrawal A, Zaid M, Cooper DJ, Bajaj N, Lin R, Xiao L, Mayo LL, Wiederhold LR, Shah SJ, Tate MK, Chronowski GM, Reddy JP, Mezera M, Mann JM, Augspurger M, Otun AO, Chambers MS, Koay EJ. Development and clinical implementation of a digital workflow utilizing 3D-printed oral stents for patients with head and neck cancer receiving radiotherapy. Oral Oncol 157:106944, 2024. e-Pub 2024. PMID: 39024700.
- Kamel S, Humbert-Vidan L, Kaffey Z, Abusaif A, Fuentes DTA, Wahid K, Dede C, Naser MA, He R, Moawad AW, Elsayes KM, Chen MM, Otun AO, Rigert J, Chambers M, Hope A, Watson E, Brock KK, Hutcheson K, van Dijk L, Moreno AC, Lai SY, Fuller CD, Mohamed ASR. Computed tomography radiomics-based cross-sectional detection of mandibular osteoradionecrosis in head and neck cancer survivors. medRxiv, 2024. e-Pub 2024. PMID: 39314948.
- Pundole X, Jones AL, Tetzlaff MT, Williams MD, Murphy WA, Otun AO, Goepfert RP, Davies MA. Osteonecrosis of the jaw induced by treatment with anti-PD-1 immunotherapy: a case report. Immunotherapy imt-2020-0108(10.2217):1213-1219, 2020. e-Pub 2020. PMID: 32900256.
- Zaid M, Koay EJ, Bajaj N, Mathew R, Xiao L, Agrawal A, Fernandes P, Burrows H, Roach MA, Wilke CT, Chung C, Fuller CD, Phan J, Gunn B, Morrison WH, Garden AS, Frank SJ, Rosenthal DL, Andersen M, Otun AO, Chambers MS. A Prospective Parallel Design Study Testing Non-Inferiority of Customized Oral Stents made using 3D printing or manual fabricated methods. Oral Oncology 106:104665(104665), 2020. e-Pub 2020. PMID: 32298994.
- Maniakas A, Jozaghi Y, Zafereo ME, Sturgis EM, Su SY, Gillenwater AM, Gidley PW, Lewis CM, Diaz E, Goepfert RP, Kupferman ME, Gross ND, Hessel AC, Pytynia KB, Nader NE, Wang JR, Lango MN, Kiong KL, Guo T, Zhao X, CMKL Y, Appelbaum E, Alpard J, Garcia JA, Terry S, Flynn JE, Bauer S, Fournier D, Burgess CG, Wideman C, Johnston M, You C, DeLuna R, Joseph L, Diersing J, Prescott K, Heiberger K, Mugartegui L, Rodriguez J, Zendehel S, Sellers J, Friddell RA, Thomas A, Khanjae SJ, Schwarzlose KB, Chambers MS, Hofstede TM, Cardoso RC, Aponte Wesson R, Won A, Otun AO, Gombos DS, Al-Zubidi N, Hutcheson KA, Gunn GB, Rosenthal DI, Gillison ML, Ferrarotto R, Weber RS, Hanna EY, Myers JN, Lai SY. SPECIAL ISSUE: Head and Neck Surgical Oncology in the Time of a Pandemic: Subsite-specific Triage Guidelines during the COVID19 Pandemic. Head and Neck 42(6):1194 - 1201, 2020. e-Pub 2020.
- Zaid M, Bajaj N, Burrows H, Mathew R, Dai A, Wilke C, Palasi S, hergenrother R, Chung C, Fuller CF, Phan J, Gunn GB, Morrison WH, Garden AS, Frank SJ, Rosenthal DI, Andersen M, Otun AO, Chambers MS, Koay EJ. Creating customized oral stents for head and neck radiotherapy using 3D scanning and printing. Radiation Oncology(14(1):148), 2019. e-Pub 2019. PMID: 31426824.
- Otun AO, Qazali AA, Won A, Chambers MS. Natural Killer T-Cell Lymphoma (Nasal-Type) Presenting Early as Pain of Odontogenic Origin. Int J Dent Oral Health 4(3):1-4, 2018. e-Pub 2018.
- Won AM, Hofstede TM, Cardoso RC, Otun AO, Chambers MS. Sunitinib and Zoledronic Acid Combination Therapy for Metastatic Renal Cell Carcinoma: Alarming for Osteonecrosis of the Jaw. Kidney Cancer Journal 15(2):49-51, 2017. e-Pub 2017.
- Otun A, Lee H, Geminiani A, Shirakura A, Ercoli C, Feng C. Ring Liner and Burn-Out Temperature Affect The Clinical Time Required to fit a Cast Post. J Prosthet Dent 102(4):224-228, 2009. e-Pub 2009. PMID: 19782824.
Review Articles
- Chi W, Myers JN, Frank SJ, Aponte-Wesson R, Otun AO, Nogueras-Gonzalez GM, Li Y, Geng Y, Chambers MS. The Effects of Zinc on Radiation-Induced Dysgeusia: A Systematic Review and Meta-Analysis. Supportive Care in Cancer 28(12):1-12, 2020. e-Pub 2020. PMID: 32642950.
- Head MD, Guidelines Consortium NST, members C, Maniakas A, Jozaghi Y, Zafereo ME, Sturgis EM, Su SY, Gillenwater AM, Gidley PW, Lewis CM, Diaz E, Goepfert RP, Kupferman ME, Gross ND, Hessel AC, Pytynia KB, Nader ME, Wang JR, Lango MN, Kiong KL, Guo T, Zhao X, CMKL Y, Appelbaum E, Alpard J, Garcia JA, Terry S, Flynn JE, Bauer S, Fournier D, Burgess CG, Wideman C, Johnston M, You C, De Luna R, Joseph L, Diersing J, Prescott K, Heiberger K, Mugartegui L, Rodriguez J, Zendehdel S, Sellers J, Friddell RA, Thomas A, Khanjae SJ, Schwarzlose KB, Chambers MS, Hofstede TM, Cardoso RC, Wesson RA, Won A, Otun AO, Gombos DS, Al-Zubidi N, Hutcheson KA, Gunn GB, Rosenthal DI, Gillison ML, Ferrarotto R, Weber RS, Hanna EY, Myers JN, Lai SY. Head and neck surgical oncology in the time of a pandemic: Subsite-specific triage guidelines during the COVID-19 pandemic. Head Neck 42(6):1194-1201, 2020. e-Pub 2020. PMID: 32342541.
- Won AM, Boddu P, Otun AO, Aponte-Wesson R, Chambers M. Chronic myelogenous leukemia presenting with osteonecrosis of the jaw as a rare but debilitating toxicity of dasatinib: A case report and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol 126(4):e208-e211, 2018. e-Pub 2018. PMID: 29941400.
Abstracts
- Chi W, Myers JN, Frank SJ, Aponte Wesson R, Otun AO, Nogueras-Gonzalez GM, Li Y, Geng Y, Chambers MS. The Effect of Zinc on Radiation Induced Dysgeusia: A Meta-Analysis. American College of Prosthodontics Annual Mtg (ACP), 2018. e-Pub 2018.
- Chi W, Myers JN, Frank SJ, Aponte-Wesson R, Otun A. The Effect of Zinc on Radiation Induced Dysgeusia: A Meta-Analysis. The Star of the South Dental Meeting, 2018. e-Pub 2018.
- Chi W, Aponte-Wesson R, Otun A. Prosthodontic Treatment of a Patient with Ewing's Sarcoma of Maxillary Left Sinus. The Star of the South Dental Meeting, 2018. e-Pub 2018.
- Qazali A, Chambers DMD, Otun AO. A Case of Nasal NK T-Cell Lymphoma. The Star of the South Dental Meeting, 2018. e-Pub 2018.
- Medina J, Chambers M, Cardoso RC, Otun A, Aponte Wesson R. Palatal Augmentation Prosthesis Comparing Hollowing Techniques for Weight Reduction. ISMR - AAMP Annual Conference 2017, 2017. e-Pub 2017.
- Otun AO, Qazali A, Won AM, Chambers M. A Case of NKT Cell Lymphoma Nasal Type Presenting as Pain of Odontogenic Origins. 4th Joint Meeting of the International Society for Maxillofacial Rehabilitation and the American Academy of Maxillofacial Prosthetics, October 2017, San Francisco, CA, 2017. e-Pub 2017.
- Medina J, Chambers M, Cardoso RC, Otun A, Aponte Wesson R. Palatal Augmentation Prosthesis Comparing Hollowing Techniques for Weight Reduction. The Star of the South Dental Meeting, 2017. e-Pub 2017.
- Otun AO, Fattouhi MM. Lymphoma-related Palatal Defects: A Report of Rehabilitation. 2025 Oral Oncology Symposium, The University of Texas MD Anderson Cancer Center.
- Otun AO, Fattouhi MM. Lymphoma-related Palatal Defects: A Report of Rehabilitation. 72nd Annual Meeting of the American Academy of Maxillofacial Prosthetics (AAMP).
- Lee, Anna, Tino,Rance Brennan Bolislis, Roach, Milli, Fuentes, Gabriela, Agrawal, Anshuman, Zaid, Mohamed, Cooper, Dylan, Lin, Ruitao, Xiao, Lianchun, Mayo, Lauren, Wiederhold, Lee R, Shah, Shalin Jyotindra, Chronowski, Gregory, Reddy, Jay Paul, Mezera, Mega, Mann, Justin, Augspurger, Mark, Otun, Adegbenga O, Chambers, Mark S, Koay, Eugene Jon. A randomized study of head and neck radiotherapy with or without customized 3D printed oral stents. The 68th American Society for Radiation Oncology (ASTRO) Annual Meeting.
Letters to the Editor
- Tino RB, Roach MA, Fuentes GD, Agrawal A, Zaid M, Cooper DJ, Bajaj N, Lin R, Xiao L, Mayo LL, Wiederhold LR, Shah SJ, Tate MK, Chronowski GM, Reddy JP, Mezera M, Mann JM, Augspurger M, Otun AO, Chambers MS, Lee A, Koay EJ. Response to recent comments on "Development and clinical implementation of a digital workflow utilizing 3D-printed oral stents for patients with head and neck cancer receiving radiotherapy". Oral Oncol 162: 107220, 2025.
Patient Reviews
CV information above last modified September 03, 2026