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Alessandra Ferrajoli

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

1988 School of Medicine, University of Perugia, Perugia, Italy, MD, Cum Laude, Internal Medicine

Board Certifications

9/2001 American Board of Medical Oncology
9/1998 American Board of Internal Medicine

Selected Publications

Peer-Reviewed Original Research Articles
1. Faderl S, Ravandi F, Huang X, Wang X, Jabbour E, Garcia-Manero G, Kadia T, Ferrajoli A, Konopleva M, Borthakur G, Burger J, Feliu J, Kantarjian HM. Clofarabine plus low-dose cytarabine followed by clofarabine plus low-dose cytarabine alternating with decitabine in acute myeloid leukemia frontline therapy for older patients. Cancer. e-Pub 1/2012. PMID: 22282348.
2. Badoux XC, Keating MJ, Wen S, Lee BN, Sivina M, Reuben J, Wierda WG, O'Brien SM, Faderl S, Kornblau SM, Burger JA, Ferrajoli A. Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia. Blood 118(13):3489-3498, 9/2011. e-Pub 7/2011. PMID: 21725050.
3. Ferrajoli A, Keating MJ, O'Brien S, Cortes J, Thomas DA. Experience with rituximab immunotherapy as an early intervention in patients with Rai stage 0 to II chronic lymphocytic leukemia. Cancer 117(14):3182-3186, 7/2011. e-Pub 1/2011. PMID: 21246526.
4. Badoux XC, Keating MJ, Wang X, O'Brien SM, Ferrajoli A, Faderl S, Burger J, Koller C, Lerner S, Kantarjian H, Wierda WG. Fludarabine, cyclophosphamide and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL. Blood 117(11):3016-3024, 3/2011. e-Pub 1/2011. PMID: 21245487.
5. Ferrajoli A. Incorporating the use of GM-CSF in the treatment of chronic lymphocytic leukemia. Leuk Lymphoma 50(3):514-516, 2009. PMID: 19347738.
6. Ferrajoli A, Lee B-L, Schlette EJ, O'Brien SM, Gao H, Wen S, Wierda WG, Estrov Z, Faderl S, Cohen EN, Li C, Reuben JM, Keating MJ. Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood 111(11):5291-5297, 2008. PMID: 18334676.
7. Ferrajoli A, Wierda WG, Lapushin R, O'Brien SM, Faderl S, Browning ML, Keating MJ. Pilot experience with continuous infusion alemtuzumab in patients with fludarabine-refractory chronic lymphocytic leukemia. Eur J Haematol 80(4):296-298, 2008. PMID: 18182081.
8. Ferrajoli A, Faderl S, Van Q, Koch P, Harris D, Liu Z, Hazan-Halevy I, Wang Y, Kantarjian HM, Priebe W, Estrov Z. WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myeloid leukemia cells. Cancer Res 67(23):11291-11299, 2007. PMID: 18056455.
9. Ferrajoli A, Faderl S, Ravandi F, Estrov Z. The JAK-STAT pathway: a therapeutic target in hematological malignancies. Curr Cancer Drug Targets 6(8):671-679, 2006. PMID: 17168672.
Other Articles
1. Ferrajoli A, O'Brien SM, Faderl S, Wierda WG, Reuben JM, Keating MJ. Lenalidomide: An emerging option in chronic lymphocytic leukemia. Haematologica Meeting Reports 3(3):103-105, 2009.

Last updated: 2/24/2012