Alexander M. Won, DDS, FACP
Department of Head and Neck Surgery, Division of Surgery
About Dr. Alexander M. Won
Dr. Alexander Won is an Associate Professor in the Department of Head and Neck Surgery Section of Oral Oncology and Maxillofacial Prosthodontics at the University of Texas MD Anderson Cancer Center. He collaborates with Head and Neck Surgery, Radiation Oncology, and Medical Oncology. His primary duties are oral evaluation and treatment of patients with head and neck cancer including prosthetic rehabilitation.
His research efforts focus on oral manifestations with patients undergoing stem cell transplant, targeted therapy, immunotherapy and bone targeted therapy.
Present Title & Affiliation
Primary Appointment
Associate Professor, Head and Neck Surgery, Surgery, The University of Texas MD Anderson Cancer Center, HOUSTON, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, HOUSTON, TX
Education & Training
Degree-Granting Education
| 2009 | Meharry Medical College, Nashville, Tennessee, US, Dentistry, DDS |
Postgraduate Training
| 2014-2015 | Clinical Fellowship, Advanced Education Program in Maxillofacial Prosthodontics and Oral Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2009-2012 | Clinical Residency, Prosthodontics, University of California, San Francisco, California |
Licenses & Certifications
| 2017 | American Board of Prosthodontics |
| 2015 | Health Care Provider: American Heart Association |
| 2015 | Drug Enforcement Agency (DEA) - US Dept of Justice |
| 2015 | Department of Public Safety (DPS) - Texas Controlled Substance |
| 2015 | Texas State Board of Dental Examiners |
| 2012 | New York Dental License |
Experience & Service
Faculty Academic Appointments
Assistant Professor, Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2021
Clinical Assistant Professor, Prosthodontics and Digital Technology, Stony Brook University School of Dental Medicine, New York, NY, 2012 - 2014
Other Professional Positions
Director, Removal prosthodontics, Stony Brook University, School of Dental Medicine, New York, NY, 2012 - 2014
Director, Year IV Advanced removable course, Stony Brook University, School of Dental Medicine, New York, NY, 2012 - 2014
Director, Removable Prosthodontics Technique, Stony Brook University, School of Dental Medicine, New York, NY, 2012 - 2014
Director, Prosthodontics clinic, Stony Brook University, School of Dental Medicine, New York, NY, 2012 - 2014
Intramural Institutional Committee Activities
Member, Program Evaluation Committee - PEC, The University of Texas MD Anderson Cancer Center, 2024 - Present
Representative, CCMS - Dept Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, 2023
Super User, Video-Conferencing Committee Epic, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, 2020
Honors & Awards
| 2025 | Top 1% Provider: Fiscal Year 2025, The University of Texas MD Anderson Cancer Center |
| 2024 | Distinguished Educator of the Year, The University of Texas MD Anderson Cancer Center |
| 2024 | Top 1% Provider: Fiscal Year 2024, The University of Texas MD Anderson Cancer Center |
| 2018 | Outstanding Literary Award, American Academy of Oral Medicine Scientific Session, 2018 (R. Acharya, Fellow 2017-18) |
| 2009 | American College of Prosthodontics Achievement Award, American College of Prosthodontics |
| 2009 | Excellence in Prosthodontics Award, Meharry College |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2026. Restoration of Maxillary Defects in Oncology. Invited. Spring Semester 2026 Oral Oncology Lecture Series. Houston, Texas, US.
- 2024. Medication related ONJ. Conference. Dental Study Club. Houston, TX, US.
- 2024. Velopharyngeal Dysfunction in Head and Neck Cancer: What's Possible?. Conference. 2024 Virtual Webinar Series: MDA Head & Neck Collaborative Webinar. Houston, TX, US.
- 2024. Velopharyngeal Dysfunction in Head and Neck Cancer: Who Nose?. Conference. 2024 Virtual Webinar Series: MDA Head & Neck Collaborative Webinar. Houston, TX, US.
- 2023. Oral Oncology Maxillary Defects. Conference. The University of Texas Health Science Center at Houston. Houston, TX, US.
- 2022. Restoration of the Maxillary Defects. Conference. The University of Texas Health Science Center at Houston. Houston, TX, US.
- 2020. Digital Planning and Fabrication of an Oral Surgical Splint for Implant Uncovering. Conference. Star of the South Dental Meeting. Houston, TX, US.
- 2018. Prosthetic Rehabilitation with a Palatal Lift/Augmentation combination prosthesis in a patient with neurologic/motor deficit due to cancer therapy for Chondrosarcoma: A clinical report. Conference. Star of the South Dental Meeting. Houston, TX, US.
- 2015. Implant-Supported and Magnet Retained Oral-Nasal Combination Prosthesis of a Patient with Total Rhinectomy and Partial Maxillectomy. Conference. Star of the South Dental Meeting. Houston, TX, US.
National Presentations
- 2026. Mucocutaneous Manifestations of Malignancy: A Diagnostic Dilemma in a Patient with Peritoneal Clear Cell Carcinoma with Presumed Paraneoplastic Pemphigus and Atypical Diagnostic Panel. Poster. 2026 AAOM Annual Conference. Chicago, Illinois, US.
- 2025. Drug Induced Osteonecrosis of the Jaw. Conference. 2025 Oral Oncology Symposium. Houston, TX, US.
- 2025. Gingival Overgrowth Associated With Immunotherapy In A Patient With Renal Cell Carcinoma: A Case Report. Albasry Z, Chambers M, Won A. Poster. 2025 AAOM/EAOM Joint Meeting. Las Vegas, NV, US.
- 2025. Case Report: Prosthetic Rehabilitation of Mandibular Reconstruction with Free Fibula Flap. Mandani A, Chambers M, Won A. Poster. 2025 Oral Oncology Symposium. Houston, TX, US.
- 2025. Gingival Overgrowth Associated With Immunotherapy In A Patient With Renal Cell Carcinoma: A Case Report. Albasry Z, Chambers M, Lei YL, Won A. Poster. 2025 Oral Oncology Symposium. Houston, TX, US.
- 2024. New Face of Osteonecrosis of the Jaw in Prosthodontics. Invited. UCSF School of Dentistry | USCF Dental Center. San Francisco, California, US.
- 2023. POSTER: Prosthetic Augmentation of a Surgically Reconstructed Mid-Facial Defect. Poster. 71st Annual Conference. San Diego, California, US.
- 2022. The New Face of Osteonecrosis of the Jaw. Conference. 2022 Oral Oncology Symposium. Houston, TX, US.
- 2022. Interdisciplinary Management of the Cancer Patient: Case Presentation and Discussion - Panel Member. Conference. 2022 Oral Oncology Symposium. Houston, TX, US.
- 2021. The New Face of Osteonecrosis of the Jaw. Invited. 68th Annual Conference. Virtual - Houston, TX, US.
- 2020. Drug Induced Osteonecrosis of the Jaws. Invited. 2020 Oral Oncology Symposium. Houston, TX, US.
- 2018. POSTER: Prosthetic Rehabilitation of Severe Microstomia and Trismus from Cancer Therapy. Invited. 65th Annual Meeting. Baltimore, MD, US.
- 2018. Tumor-induced hypophosphatemic osteomalacia caused by a mesenchymal tumor of the mandible managed by a segmental mandibulectomy and microvascular reconstruction with a free fibula flap. Invited. 65th Annual Meeting. Baltimore, MD, US.
- 2017. POSTER: A Case of NKT Cell Lymphoma Nasal Type Presenting as Pain of Odontogenic origins. Invited. 64th Annual Meeting. San Francisco, CA, US.
- 2017. Drug Induced Osteonecrosis of the Jaws. Invited. 2017 Oncologic Dentistry & Maxillofacial Prosthetics Symposium. Houston, TX, US.
- 2017. Interdisciplinary Management of the Cancer Patient: Case Presentations /Discussions. Invited. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
Grant & Contract Support
| Date: | 2025 - 2030 |
| Title: | Determining the Interconnections Among Oral Health, Diet Quality, and Cancer Outcomes in Oropharyngeal Cancer Patients |
| Funding Source: | NIH/NIDCR |
| Role: | Co-I |
| ID: | 1R01 DE035214-01 |
Selected Publications
Peer-Reviewed Articles
- Won AM. Immune Checkpoint Inhibitors: From Promise to Plateau—How Toxicity, Resistance, and Biomarker Gaps Shaped Outcomes, and Strategies to Overcome Them. JIPO. e-Pub 2026.
- Won AM. Intralesional Nivolumab in Oral Premalignant Lesions: A First-in-Human Phase 1 Trial. NEJM. e-Pub 2026.
- Aldosari AM, Singla G, Swain VL, Won AM, Chambers MS. Pharyngeal obturator using a combined conventional and digital approach: A clinical report. J Prosthet Dent 135(6):e176-e179, 2026. e-Pub 2026. PMID: 41494913.
- Moreno AC, Watson EE, Humbert-Vidan L, Peterson DE, van Dijk LV, Urbano TG, Van den Bosch L, Hope AJ, Katz MS, Hoebers FJP, Wesson RAA, Bates JE, Bossi P, Dayo AF, Dore M, Fregnani ER, Galloway TJ, Gelblum DY, Hanna IA, Henson CE, Kiat-Amnuay S, Korfage A, Lee NY, Lewis CM, Lynggaard CD, Makitie AA, Magalhaes M, Mowery YM, Munoz-Montplet C, Myers JN, Orlandi E, Patel J, Rigert JM, Saunders D, Schoenfeld JD, Selek U, Somay E, Takiar V, Thariat J, Verduijn GM, Villa A, West N, Witjes MJH, Won A, Wong ME, Yao CMKL, Young SW, Al-Eryani K, Barbon CEA, Buurman DJM, Dieleman FJ, Hofstede TM, Khan AA, Otun AO, Robinson JC, Hum L, Johansen J, Lalla R, Lin A, Patel V, Shaw RJ, Chambers MS, Ma D, Singh M, Yarom N, Mohamed ASR, Hutcheson KA, Lai SY, Fuller CD. International Expert-Based Consensus Definition, Classification Criteria, and Minimum Data Elements for Osteoradionecrosis of the Jaw: An Inter-Disciplinary Modified Delphi Study. Int J Radiat Oncol Biol Phys 122(2):341-354, 2025. e-Pub 2025. PMID: 39826846.
- Moreno AC, Won AM, Fuller CD. International Expert-Based Consensus Definition, Staging Criteria, and Minimum Data Elements for Osteoradionecrosis of the Jaw: An Inter-Disciplinary Modified Delphi Study. Journal of Clinical Oncology, 2025. e-Pub 2024. PMID: 38645105.
- Alqarni H, Montgomery P, Aponte-Wesson R, Won A, Hofstede TM, Chambers MS. Combined rehabilitation of a lower lip defect after resection of floor of mouth cancer: A Clinical Report. J Prosthet Dent 128(6):1369-1374, 2022. e-Pub 2022. PMID: 33867164.
- Asfar MM, Won AM, Skoracki R, Hofstede TM. Maxillary Reconstruction of an Adolescent Patient with Mucoepidermoid Carcinoma: A Clinical Report. Texas Dental Journal 138(6):382 - 395, 2021. e-Pub 2021.
- Srivastava A, Nogueras Gonzalez GM, Geng Y, Won A, Cabanillas ME, Naing A, Myers JN, Li Y, Chambers MS. Prevalence of medication related osteonecrosis of the jaw in patients treated with sequential antiresorptive drugs: systematic review and meta-analysis. Support Care Cancer 29(5):2305-2317, 2021. e-Pub 2021. PMID: 33190182.
- Head MD, Consortium members NSTGC, Maniakas A, Jozaghi Y, Zafereo ME, Sturgis EM, Su SY, Gillenwater AM, Gidley PW, Lewis CM, Diaz E, Goepfert RP, Kupferman ME, Gross ND, Hessel AC, Pytynia KB, Nader NE, Wang JR, Lango MN, Kiong KL, Guo T, Zhao X, CMKL Y, Appelbaum E, Alpard J, Garcia JA, Terry S, Flynn JE, Bauer S, Fournier D, Burgess CG, Wideman C, Johnston M, You C, DeLuna R, Joseph L, Diersing J, Prescott K, Heiberger K, Mugartegui L, Rodriguez J, Zendehel S, Sellers J, Friddell RA, Thomas A, Khanjae SJ, Schwarzlose KB, Chambers MS, Hofstede TM, Cardoso RC, Aponte Wesson R, Won AM, Otun AO, Gombos DS, Al-Zubidi N, Hutcheson KA, Gunn GB, Rosenthal DI, Gillison ML, Ferrarotto R, Weber RS, Hanna EY, Myers JN, Lai SY. Surgery Treatment Guidelines Consortium: Head and Neck Surgical Oncology in the Time of a Pandemic: Subsite-specific Triage Guidelines During the COVID19 Pandemic. Head and Neck 42(6):1194 - 1201, 2020. e-Pub 2020. PMID: 32342541.
- Acharya RP, Won AM, Moon BS, Flint JH, Roubaud MS, Williams MD, Hessel AC, Murphy WA Jr, Chambers MS, Gagel RF. Tumor-induced hypophosphatemic osteomalacia caused by a mesenchymal tumor of the mandible managed by a segmental mandibulectomy and microvascular reconstruction with a free fibula flap. Head Neck 41(6):E93-E98, 2019. e-Pub 2019. PMID: 30859653.
- Asfar MM, Hutcheson KA, Won AM. Prosthetic rehabilitation with palatal lift/augmentation in a patient with neurologic/motor deficit due to cancer therapy of chondrosarcoma. J Prosthodont 28(3):234-238, 2019. e-Pub 2019. PMID: 30357985.
- Otun AO, Qazali AA, Won AM, Chambers MS. Natural Killer T-Cell Lymphoma (Nasal-Type) Presenting Early as Pain of Odontogenic Origin. International Journal of Dentistry and Oral Health 4(3), 2018. e-Pub 2018.
- Boddu P, Chen PL, Nagarajan P, Prieto VG, Won AM, Chambers MS, Kornblau S. Necrotizing fungal gingivitis in a patient with acute myelogenous leukemia: Visible yet obscure. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 30(1):50-54, 2017. e-Pub 2017. PMID: 29404266.
- Won AM, Hofstede TM, Cardoso RC, Otun AO, Chambers MS. Sunitinib and Zoledronic Acid Combination Therapy for Metastatic Renal Cell Carcinoma: Alarming for Osteonecrosis of the Jaw. Kidney Cancer Journal 15(2):49-52, 2017. e-Pub 2017.
- Won AM, Montgomery P, Aponte-Wesson R, Chambers M. Implant-supported and magnet-retained oral-nasal combination prosthesis in a patient with total rhinectomy and partial maxillectomy due to cancer: a clinical report. J Prosthet Dent 117(2):315-320, 2016. e-Pub 2016. PMID: 27666495.
- Delgado-Ruiz RA, Calvo-Guirado JL, Abboud M, Ramirez-Fernández MP, Maté-Sánchez JE, Negri B, Won A, Romanos G. Porous titanium granules in critical size defects of rabbit tibia with or without membranes. Int J Oral Sci 6(2):105-10, 2014. e-Pub 2014. PMID: 24556954.
- Won AM, Hofstede TM, Chambers MS, Aponte Wesson R. Destruction of the hard palate and oral nasal communication caused by pervious treatment with sunitinib and zoledronic acid: Case Report. J. Med Case Rep.
- Won AM, Aponte Wesson R, Chambers MS. A Simple Flap Guard for Protection of Intraoral Anterolateral Thigh Flap Construction. JPRAS Open.
Review Articles
- Srivastava A, Nogueras Gonzalez GM, Geng Y, Won A, Myers J, Li Y, Chambers MS. Medication-Related Osteonecrosis of the Jaw in Patients Treated Concurrently with Antiresorptive and Antiangiogenic Agents: Systematic Review and Meta-Analysis. J Immunother Precis Oncol 4(4):1-12, 2021. e-Pub 2021. PMID: 35665023.
- Won AM, Boddu P, Otun AO, Aponte-Wesson R, Chambers MS. Chronic myelogenous leukemia presenting with osteonecrosis of jaw as a rare but debilitating toxicity of dasatinib: A case report and literature review. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology 126(4):e208-e211, 2018. e-Pub 2018. PMID: 29941400.
Abstracts
- Alouthah H, Won AM, Chambers M. Cosmetic Functional Maxillary Resection Prosthesis: A Modern Concept. MD Anderson Cancer Center Research Day, 2024. e-Pub 2024.
- Kazim S, Won AM, Chambers M. Soft palate obturator fabrication incorporating computer-aided design and 3-dimensional laser sintering technology: A Clinical Report. MD Anderson Cancer Center Research Day, 2024. e-Pub 2024.
- Rivera-Rivera LP, Alqarni H, Nguyen C, Montgomery P, Hofstede TM, Aponte Wesson R, Won AM. Digital Planning and Fabrication of an Oral Surgical Splint for Implant Uncovering. The Greater Houston Dental Society - Star of the South Dental Meeting, 2020. e-Pub 2020.
- Acharya RP, Won AM, Chambers MS, Gagel RF, Hessel AC, Murphy WA. Tumor-Induced Hypophosphatemic Osteomalacia caused by a Mesenchymal tumor of the mandible managed by a segmental mandibulectomy and microvascular reconstruction with a free fibula flap. American Academy of Maxillofacial Prosthetics Annual Conference, 2018. e-Pub 2018.
- Acharya RP, Won AM, Graham WC, Chambers MS. Prosthetic Rehabilitation of Severe Microstomia and Trismus from Cancer Therapy. American Academy of Maxillofacial Prosthetics, 2018. e-Pub 2018.
- Acharya RP, Won AM. Oncogenic Osteomalacia Caused by a Phosphaturic Mesenchymal Tumor of the Mandible: A Case Report. Poster Session, Advances in Oral Medicine, Presented at the American Academy of Oral Medicine (AAOM) Meeting, San Antonio, TX, 2018. e-Pub 2018.
- Otun AO, Won AM. A Case of NKT Cell Lymphoma Nasal Type Presenting as Pain of Odontogenic Origins. ISMR & AAMP 4th Joint Conference 2017: California. Accepted, 2017. e-Pub 2017.
- Asfar M, Hutcheson K, Won AM. Prosthetic rehabilitation with palatal lift/augmentation in a patient with neurologic/motor deficit due to cancer therapy of chondrosarcoma. The Greater Houston Dental Society - Star of the South Dental Meeting, 2017. e-Pub 2017.
- Won A, Aponte-Wesson R, Montgomery P, Wesley P, Chambers M. Implant-supported and magnet retained oral-nasal combination prosthesis of a patient with total rhinectomy and partial maxillectomy due to cancer: A clinical report. Presented at the Proceedings of the Star of the South Dental Meeting 2015, Star of the South Annual Session, Houston, TX, 2015. e-Pub 2015.
- Abboud M, Delgado-Ruiz RA, Won A. Influence of angled implant position on bone strains and stress. Materials Research, Presented at the European Academy of Osseointegration (EAO) Meeting, Dublin, Ireland, 2013. e-Pub 2013.
- Abboud M, Delgado-Ruiz RA, Won A. Influence of different drills on the primary implant stability. Materials Research, Presented at the European Academy of Osseointegration (EAO) Meeting, Dublin, Ireland, 2013. e-Pub 2013.
- Abboud M, Delgado-Ruiz R, Won A. Evaluation of a new titled implant design used for the All on 4 concept. Implant Therapy Outcomes, Presented at the European Academy of Osseointegration (EAO) Meeting, Dublin, Ireland, 2013. e-Pub 2013.
- Sarpong, Alex, Won, AM. Prosthetic Augmentation of a Surgically Reconstructed Mid-Facial Defect. American Academy of Maxillofacial Prosthondontics (AAMP).
Book Chapters
- Cardoso RC, Hofstede TM, Martin JW, Garden AS, Aponte-Wesson RA, Montgomery P, Won A, Chambers MS. Chapter 29: Oral and Maxillofacial Rehabilitation of Patients with Head and Neck Cancer. In: Cancer of the Head and Neck. Wolters Kluwer, 2016.
- Aponte-Wesson R, Hofstede TM, Cardoso RC, Montgomery P, Won A, Martin JW, Chambers M. Chapter 54 Oral Oncology. In: Head and Neck Cancer: Multimodality Management 2nd Edition. Springer Science + Business Media, 2015.
Patient Reviews
CV information above last modified September 02, 2026