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Amanda Olson, MD

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Stem Cell Transplantation, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Bio Statement

I completed Hematology and Oncology fellowship at Memorial Sloan-Kettering in 2013 where my research focus was related to optimization of umbilical cord blood transplantation and infectious complications following hematopoietic stem cell transplant in adults.  I am currently an Assistant Professor of Medicine in the Department of Stem Cell Transplantation and Cellular Therapy where I oversee clinical research related to cord blood transplantation, mesenchymal stem cell manipulation and cellular therapy. I am the Principal Investigator for several cellular therapy trials including a Phase I trial of mesenchymal stem cells transfected with plasmid containing interferon beta for the treatment of refractory epithelial ovarian cancer, an international multi-institutional Phase III study evaluating the use of cord blood derived mesenchymal stem cell expansion to expedite hematopoietic engraftment following stem cell transplantation, a Phase I trial of IV mesenchymal stem cells for the use of cardiac regeneration following chemotherapy induced cardiomyopathy and a Phase II trial of cytotoxic T-lymphocytes the treatment of BK cystitis in stem cell transplant recipients.

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Boulevard
Unit Number: 423
Houston, TX 77030
Room Number: FC5. 3004
Phone: 713-745-1505
Fax: 713-794-4902
Email: alolson@mdanderson.org

Education & Training

Degree-Granting Education

2007 The Medical College of Georgia School of Medicine, Augusta, GA, MD, Internal Medicine
2003 University of Georgia, Athens, GA, BS, Medicine

Postgraduate Training

7/2010-7/2013 Fellowship, Hematology and Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY
7/2008-7/2010 Residency, Internal Medicine, Baylor College of Medicine, Houston, TX
7/2007-7/2008 Internship, Internal Medicine, Baylor College of Medicine, Houston, TX
6/2004-8/2004 Research Fellowship, National Institute of Health, Bethesda, MD

Board Certifications

2010 Internal Medicine

Honors and Awards

2012-2013 The Lymphoma Foundation, Mortimer J. Lacher Fellowship
2012 The Future of Stem Cell Transplantation, American Society of Hematology

Selected Publications

Peer-Reviewed Original Research Articles

1. Thompson PA, Rezvani K, Hosing CM, Oran B, Olson AL, Popat UR, Alousi AM, Shah ND, Parmar S, Bollard C, Hanley P, Kebriaei P, Cooper L, Kellner J, McNiece IK, Shpall EJ. Umbilical cord blood graft engineering: challenges and opportunities. Bone Marrow Transplant 50 Suppl 2:S55-62, 6/2015. PMID: 26039209.
2. Olson AL, McNiece IK. Novel clinical uses for cord blood derived mesenchymal stromal cells. Cytotherapy. e-Pub 3/2015. PMID: 25819838.
3. Saliba RM, Rezvani K, Leen A, Jorgensen J, Shah N, Hosing C, Parmar S, Oran B, Olson A, Mehta RS, Chemaly R, Saunders IM, Bollard CM, Shpall EJ. General and Virus-Specific Immune Cell Reconstitution Following Double Cord Blood Transplantation. Biol Blood Marrow Transplant. e-Pub 2/2015. PMID: 25708219.
4. Uday Popat, Rohtesh S Mehta, Katayoun Rezvani, Patricia Fox, Kayo Kondo, David Marin, Ian McNiece, Betul Oran, Chitra Hosing, Amanda Olson, Simrit Parmar, Nina Shah, Michael Andreeff, Partow Kebriaei, Indreshpal Kaur, Eric Yvon, Marcos de Lima, Laurence JN Cooper, Priti Tewari, Richard E Champlin, Yago Nieto, Borje S Andersson, Amin Alousi, Roy B Jones, Muzaffar H Qazilbash, Qaiser Bashir, Stefan Ciurea, Sairah Ahmed, Paolo Anderlini, Doyle Bosque, Catherine Bollard, Jeffrey J. Molldrem, Julianne Chen, Gabriela Rondon, Michael Thomas, Leonard Miller, Steve Wolpe, Paul Simmons, Simon Robinson, Patrick A Zweidler-McKay, and Elizabeth J Shpall. Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation. BLOOD, 2015.
5. Munoz J, Shah N, Rezvani K, Hosing C, Bollard CM, Oran B, Olson A, Popat U, Molldrem J, McNiece IK, Shpall EJ. Concise review: umbilical cord blood transplantation: past, present, and future. Stem Cells Transl Med 3(12):1435-43, 12/2014. e-Pub 11/5/2014. PMCID: PMC4250219.
6. Dahi PB, Perales MA, Devlin SM, Olson A, Lubin M, Gonzales AM, Scaradavou A, Kernan NA, O'Reilly RJ, Giralt S, Jakubowski A, Koehne G, Papadopoulos EB, Ponce DM, Sauter C, Papanicolaou G, Barker JN. Incidence, nature and mortality of cytomegalovirus infection after double-unit cord blood transplant. Leuk Lymphoma. e-Pub 10/21/2014. PMID: 25224458.
7. Olson AL, Dahi PB, Zheng J, Devlin SM, Lubin M, Gonzales AM, Giralt SA, Perales MA, Papadopoulos EB, Ponce DM, Young JW, Kernan NA, Scaradavou A, O'Reilly RJ, Small TN, Papanicolaou G, Barker JN. Frequent human herpesvirus-6 viremia but low incidence of encephalitis in double-unit cord blood recipients transplanted without antithymocyte globulin. Biol Blood Marrow Transplant 20(6):787-93, 6/2014. e-Pub 2/2014. PMID: 24548875.
Other Articles
1. A.L. Olson, P. Dahi, J. Zheng, S.M. Devlin, M. Lubin, A.M. Gonzales, S. Giralt, D. Ponce, N.A. Kernan, A. Scaradavou, G. Papanicolaou, J.N. Barker. HHV-6 Viremia is Frequent but the Incidence of Encephalitis is Low in Double-Unit Cord Blood Transplant Recipients Transplanted without ATG. Biology of Blood and Marrow Transplantation 19(2):S125, 2013.
2. P. Dahi, A.L. Olson, S. Devlin, M. Lubin, A.M. Gonzales, K. Evans, A. Scaradavou, N. Kernan, T. Small, R. O'Reilly, S.A. Giralt, G. Koehne, M.A. Perales, D. Ponce, Z. Papanicolaou, & J.N. Barker. Incidence, Nature, Risk Factors and Outcomes of Cytomegalovirus Infection After Double-Unit Cord Blood Transplantation. Biology of Blood and Marrow Transplantation 19(2):S344-S345, 2013.
3. A.L. Olson, R. Lehrman, S.M. Devlin, M. Maloy, H. Castro-Malaspina, S.A. Giralt, J.D. Goldberg, R.J. O'Reilly, M.A. Perales, E.B. Papadopoulos, & A.A. Jakubowski. The Prognostic Significance of Peripheral Blood Mixed Chimerism After T-Cell Depleted Allogeneic Stem Cell Transplant. Biology of Blood and Marrow Transplantation 19(2):S301-302, 2013.
4. A.L. Olson, S.M. Devlin, M. Maloy, R. Lehman, J.N. Barker, H. Castro-Malaspina, S.A. Giralt, JH.D. Goldberg, R.J O'Reilly, M.A. Perales, E.B. Papadopoulos, A.A. Jakubowski. Bone marrow mixed chimerism is a risk factor for relapse after T-cell depleted allogeneic stem cell transplant. Blood, 2012.
5. A.L. Olson, P. Dahi, J. Zheng, S.M. Devlin, M. Lubin, A.M. Gonzales, S. Giralt, D. Ponce, N.A. Kernan, A. Scaradavou, G. Papanicolaou, J.N. Barker. HHV-6 Viremia is Frequent but the Incidence of Encephalitis is Low in Double-Unit Cord Blood Transplant Recipients Transplanted without ATG. Blood, 2012.
6. L.S. Schwartzberg, M. Beeram, A. Patnaik, A.W. Tolcher, L. Itri, A.L. Olson, A.D. Seidman. Tesetaxel, an advanced-generation oral taxane, as first-line treatment in women with metastatic breast cancer. Journal of Clinical Oncology, 2011.
7. A.L. Olson, G.N. Hortobagyi, K.M. Hahn. Cervical and colorectal screening among breast cancer survivors followed in either a breast center of a breast survivorship clinic at The University of Texas M.D. Anderson Cancer Center. Journal of Clinical Oncology, 2009.

Abstracts

1. Amanda Olson, Rima M Saliba, Betul Oran, Julien Chen, Amin Alousi, Sairah Ahmad, Qaizer Bashir, Stefan Ciurea, Chitra Hosing, Roy Jones, Partow Kebriaei, Issa Khouri, Yago Nieto, Simrit Parmar, Nina Shah, Elizabeth Shpall, Muzaffar Qazilbash, Borje Andersson, Richard Champlin, Uday Popat. Cytogenetics and Blast Count Determine Outcomes Advanced AML. Biology of Blood and Marrow Transplantation, 2/2015.
2. Ahmed S, Shpall E, Gulbis A, Jones R, Martinez C, Rondon G, Rezvani K, Oran B, Olson A, Shah N, Parmar S, Popat U, Alousi A, Nieto Y, Hosing C, Bashir Q, Kebriaei P, Qazilbash M, Champlin R, Mulanovich V. Assessment of Incidence Toxoplasma Gondii Infection and Outcomes in Allogeneic Stem Cell Patients. American Society of Hematology, 12/2014.
3. Oran B, Cao K, Saliba R, Hosing C, Popat U, de Lima M, Carmazzi Y, Alousi A, Kebriaei P, Nieto Y, Rondon G, Willis D, Shah N, Parmar S, Olson A, Moore B, Champlin R, Rezvani K, Shpall E. Higher Allele Level HLA Matching Improves Prognostication after Double Umbilical Cord Blood (dUCB) Transplantation for Hematological Malignancies. American Soiety of Hematology, 12/2014.
4. Popat U, Fox Patricia, Bassett R, Chen J, Valdez B, Kawedia J, Ahmed S, Alousi A, Bashir Q, Ciurea S, Hosing C, Jones R, Kebriaei P, Khouri I, Nieto Y, Olson A, Oran B, Parmar S, Qazilbash M, Shah N, Shpall E, Andersson B, Champlin R. Myeloablative Timed Sequential Busulfan Is Safe in Older Patients. American Society of Hematology, 12/2014.

Book Chapters

1. Olson, A and Shpall, E. Chapter 11 – Cord Blood Cells for Clinical Use: Expansion and Manipulation. In: Cord Blood Stem Cells and Regenerative Medicine, 2015. ISBN: 9780124077850.
2. A.L. Olson. Allogeneic Stem Cell Transplantation, Autologous Stem Cell Transplantation, Chronic Myelogenous Leukemia. In: PocketOncology. Ed(s) Alexander Drilon, Michael Postow. Lippincott Williams and Wilkins Publishers, 2014.

Grant & Contract Support

Title: Mesenchymal Stem Cells as Tumor-Tropic Vehicles for Ovarian Cancer Treatment
Funding Source: NIH/NCI
Role: Collaborator
Principal Investigator: Bast
Duration: 2010 - 2015

Last updated: 8/12/2015