Ann M. Killary, Ph.D.
Department of Translational Molecular Pathology, Division of Pathology-LabMedicine-Research
Present Title & Affiliation
Primary Appointment
Professor (tenured), Department of Translational Molecular Pathology, Division of Pathology-LabMedicine-Research, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Professor (tenured), Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
- Tumor suppressor genes
- Breast and Pancreatic Cancer
- Cancer genetics
Little is known about the genetic pathways that discriminate breast cancer in young women from those that occur more commonly in the general population with later age of onset. Suppression subtractive hybridization has identified a novel gene DEAR1 which maps into a region of high frequency loss of heterozygosity (LOH) in a number of histologically diverse human cancers and for which we have evidence of its role in the evolution of breast cancer and for its potential as a prognostic marker in early onset breast cancer. A major project in the laboratory involves the characterization of DEAR1 function to elucidate its role in development and cancer.
Our laboratory is also a biomarker discovery laboratory funded by the Early Detection Research Network of the National Cancer Institute. Goals in this regard are focused on the use of functional genomic strategies to identify pathways aberrant in pancreatic cancer from which novel biomarkers for the early detection of pancreatic cancer can be identified.
View a complete list of Dr. Killary's publications.
Education & Training
Degree-Granting Education
| 1981 | The University of Texas Graduate School of Biomedical Sciences, Houston, Texas, US, Genetics, Ph.D |
| 1977 | The University of Texas Graduate School of Biomedical Sciences, Houston, Texas, US, Biochemistry, M.S |
| 1975 | The University of Texas, Austin, Texas, US, Biology, BA |
Postgraduate Training
| 1981-1985 | Postdoctoral Fellow, University of Southern California Medical School, Los Angeles, California |
Experience & Service
Faculty Academic Appointments
Professor (tenured), Department of Genetics (formely Department of Molecular Genetics), The University of Texas M. D. Anderson Cancer Center, Houston, TX, 2003 - 2013
Associate Professor (tenured), Department of Molecular Genetics, Section of Cancer Genetics, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 2001 - 2003
Associate Biochemist and Associate Professor (tenured), Department of Division of Pathology and Laboratory Medicine (formerly Division of Laboratory Medicine),, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 1993 - 2001
Assistant Biochemist and Assistant Professor (tenure track), Department of Division of Laboratory Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 1989 - 1993
Assistant Professor of Genetics (tenure track), Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio,, San Antonio, TX, 1985 - 1989
Administrative Appointments/Responsibilities
Special Advisor, Edge T32 Training Program External Advisory Committee at the University of Texas Health San Antonio, San Antonio, TX, 2024 - Present
ex officio officer as Historian, Executive Committee of the Faculty Senate, The University of Texas MD Anderson Cancer Center, HOUSTON, TX, 2021 - 2023
Special Advisor, Moffit Cancer Center External Advisory Committee for T32 program, Houston, TX, 2021 - Present
Past Chair, Faculty Senate, The University of Texas MD Anderson Cancer Center, HOUSTON, TX, 2020 - 2021
Co-Chair, The University of Texas System Working Group on Physician Burnout, Austin, TX, 2019 - Present
Co-Chair, Health Affairs Subcommittee, The University of Texas System Faculty Advisory Council, Houston, TX, 2019 - 2020
Chair, Faculty Senate, The University of Texas MD Anderson Cancer Center, HOUSTON, TX, 2019 - 2020
Member, Moffitt Cancer Center NIH T32 External Advisory Board, HOUSTON, TX, 2019 - Present
Chair-Elect, Faculty Senate, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2019
Co-Chair, The University of Texas MD Anderson Cancer Center Institutional Wellness Council - Crews Council, Houston, TX, 2018 - 2020
Board Member, Texas Genetics Society, HOUSTON, TX, 2017 - 2020
Co-Chair, University of Texas System Steering Committee on Physician Burnout, Houston, TX, 2017
Past Chair, The University of Texas System Faculty Advisory Council, Houston, TX, 2016 - 2017
Faculty Senate Navigator, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - 2018
Chair, University of Texas System Faculty Advisory Council, Houston, TX, 2015 - 2016
Director, Department of Translational Molecular Pathology, Interdisciplinary Education and Research Training (ITERT) program, Houston, TX, 2015 - 2018
Representative, Representative of University of Texas System Faculty Advisory Council at the University of Texas Board of Regents Health Affairs Committee and Meeting at Large, Houston, TX, 2015 - 2017
Director, Program in Human and Molecular Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2017
Past Chair, Faculty Senate, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2015
Chair-Elect, The University of Texas System Faculty Advisory Council, Houston, TX, 2014 - 2015
Director of Education and Mentoring, Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2018
Chair, Faculty Senate, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2014
Director, Department of Translational Molecular Pathology, TMP Fellowship Program, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2016
Co-Director, Program in Human and Molecular Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2014
Chair-Elect, Faculty Senate, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2013
Director, Department of Molecular Cytogenetics Core Facility, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2013
Inaugural President, The University of Texas Health Science Center Graduate School of Biomedical Sciences Alumni Association, Houston, TX, 2000 - 2001
Ombudsperson to the M. D. Anderson graduate students, The University of Texas Health Science Center, Graduate School of Biomedical Sciences, Houston, TX, 1996
Deputy Division Head for Research, Department of Division of Laboratory Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 1995 - 1998
Chief, Section of Experimental Laboratory Medicine, Department of Division of Pathology and Laboratory Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 1995 - 2000
Director, Program in Human and Molecular Genetcis, The University of Texas Graduate School of Biomedical Sciences, Houston, TX, 1995 - 1998
Deputy Division Head for Research (Ad Interim), Department of Division of Laboratory Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 1994 - 1995
Other Professional Positions
Member, University of Texas System Task force to write the UTS policy on institutional conflict of interest, Houston, TX, 2016
Member, University of Texas System Task Force to write UTS125 on Intellectual Property, Houston, TX, 2015 - 2016
Member, Prioritization Subcommittee, National Cancer Institute Early Detection Research Network, Houston, TX, 2011 - 2014
Member, Technology Development and Infrastructure, National Cancer Institute Early Detection Research Network, Houston, TX, 2008 - 2011
Member, Subcommittee on Communication, National Cancer Institute Early Detection Research Network, Houston, TX, 2004 - 2008
Member, Steering Committee, National Cancer Institute Early Detection Research Network, Houston, TX, 2004 - 2017
Member, Gastrointestional Collaborative Group, National Cancer Institute Early Dectection Research Network, Houston, TX, 2004 - 2015
Member, Board of Directors, The University of Texas Health Science Center Graduate School of Biomedical Sciences Alumni Association, Houston, TX, 2000 - 2003
Member, Human Chromosome 3 Genome Advisory Board, National Institutes of Health, Human Genome Project, National Institutes of Health, TX, 1995
Institutional Committee Activities
Member, Institutional Conflict of Interest Committee, 2021
Member, Executive Committee of the Faculty Senate Policy Review Task Force, 2021 - Present
Member, Senior Faculty Committee, 2020 - 2022
Member, Cancer Biology T32 Internal Advisory Board, 2020 - Present
Member, Employee Engagement Council, 2020 - Present
Member, Division of Pathology and Laboratory Medicine Education and Training Committee, 2020 - Present
Member, Strategic Position Management Committee (SPMC), 2020 - 2021
Member, Research CCLT, 2020 - 2021
Moderator, Faculty Senate Sponsored Town Hall on Senate Bill 212 related to Sexual Harassment, 2019
Participant, Shared Governance Teleconference, Memorial Sloan Kettering Faculty Senate, 2019
Advisor, T32 fellows on organization of Inaugural T32 Symposium, 2019
Member, Mentoring Committee for Dr. Cara Haymaker, 2019 - 2020
ex officio member, Moonshots Executive Committee, 2019 - 2021
Member, Executive Committee of the Physicians Referral Service,, 2019 - 2020
Member, Charles LeMaistre Outstanding Achievement Award Selection Committee, 2019
Member, Leading Others Task Force, 2019
Member, Institutional Task Force on Sexual Harassment, 2019 - 2020
Member, Kripke Legend Achievement Award Selection Committee, 2018 - 2019
Member, Institutional CREWS steering committee related to Burnout and Engagement, 2018
Co-Chair, CREWS Council, 2018 - 2020
Participant, ROPR operational priority reviews, 2018 - 2019
Co-Facilitator, Provider Experience Listening Session, 2018
Member, Chief Medical Officer Search Committee, 2018
Member, SGC Accountability Task Force, 2018
Member, Search Committee for the Chief Scientific Officer, 2018
Member, Search Committee for the Chief Medical Officer, 2018
Member, President’s Advisory Council, 2018 - 2021
Member, Operational Task Force –Decisive Discoveries Across the Lifespan, 2017
Member, CREWS Core, 2017 - 2018
Member, Shared Governance Committee, 2017 - 2018
Member, Institutional Faculty Mentoring Committee, 2016 - Present
Chair, Faculty Senate Subcommittee on Promotion and Tenure Issues, 2015 - 2016
Member, Institutional Campus Carry Task Force, 2015 - Present
Chair, Faculty Senate Elections Committee, 2015 - 2016
Member, CCSG Tissue Bank Oversight Committee, 2014 - 2015
Moderator, Faculty Forum to Present and Discuss the Big Survey, 2014
Member, Faculty Achievement Award Committee for Education, 2014
Member, Internal Advisory Committee for the Scientific Review of the Institute for Applied Cancer Science, 2013
Reviewer, Margaret Kirpke Award Committee, 2013 - 2014
Senate Representative, Institutional Salary Review Committee, 2013 - 2014
Participant, Strategic Planning Retreat, 2013
Moderator, Faculty Forum on Clinical Productivitty and Finances, 2013
Member, Institutional Research Executive Committee, 2013 - 2014
Chair, Instiutional Faculty Advisory Committee, 2013 - 2014
Co-Chair, Institutional Faculty Advisory Committee Task Force on Communication and Transparency, 2013 - 2015
Member, Internal Advisory Committee, Institute for Applied Cancer Science, 2013 - 2014
Member, Oversight Committee for Cell Line Authentication, STR Studies, 2012 - 2013
Member, Multidisciplinary Research Project Grant Review Committee, 2012 - 2015
Invited Participant, Triple Negative Breast/Women's Cancer Moon Shot, 2012 - Present
Member, Institutional Faculty Advisory(IFaC) Committee, 2012 - 2015
Grant Reviewer, Institutional G.S. Hogan Grants, 2011
Member, Executive Committee of the Faculty Senate, 2011 - Present
Member, Metastasis Research Center, 2011 - 2013
Chair, Oversight Committee for the Molecular Cytogenetics Facility, 2010 - 2013
Faculty Senator, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 2010 - 2012
Co-Chair, Faculty Senate Oversight Committee on Conflict Resolution (SOCCR), 2010 - 2011
Member, Genetics and Genomic Center, 2010 - 2013
Member, TRIUMPH Postdoctoral Fellowship Committee, 2008 - 2011
Member, Executive Committee of the Faculty Senate, 2008 - 2010
Chair, Parking and Transportation Committee, 2007
Member, Employee Insurance Advisory Committee to teh UT System Committee on Insurance, 2007 - 2009
Member, Oversight Committee for the Institutional DNA/RNA Isolation Core Facility, 2007 - 2008
Chair, Institutional Research Program Study Section, 2006 - 2006
Vice-Chair, Institutional Research Program Study Section, 2006 - 2006
Member, Knudson Dissertation Award Committee, 2006
Member, Parking and Transportation Committee, 2005 - 2007
Member, Executive Committee for the Pancreatic Specialized Program of Research Excellence (SPORE), 2005 - 2007
Faculty Senator, Center Faculty Senate, 2005 - 2010
Chair, Odyssey Fellowship and Scholarship Review Committee, 2004 - 2005
Chair, Institutional Research Program Study Section, 2002 - 2003
Member, Odyssey Fellowship and Scholarship Review Committee, 2002 - 2005
Member, Faculty Achievement Award Committee for Education (Clinical), 2002
Vice-Chair, Institutional Research Program Study Section, 2001 - 2002
Member, Institutional Research Program Study Section, 2000 - 2003
Member, Search Committee, Chair, Biostatistics Department, 1998
Alternate Member, Study Section of the Research Council for the Multidisciplinary Research Program (MRP) proposals, 1998 - 2002
Member, Steering Committee, Human Clinical Genetics Program, 1998
Member, Steering Committee, Human Cancer Genetics Program, 1998
Member, Faculty Achievement Award Committee for Education, 1998
Member, Search Committee for Chair, Human Cancer Genetics, 1997
Member, Search Committee for Director, Clinical Human Cancer Genetics, 1997
Participant, Basic Science Faculty Compensation Working Group, Sub-committee of the Faculty Compensation Advisory Committee, 1997
Member, Steering Committee, Women Faculty and Administrators Organization, 1996 - 1997
Member, Institutional Academic Excellence Committee, 1996
Member, Institutional Audit Committee, 1995 - 1998
Member, Institutional Research Direction Small Task Force, 1995 - 1996
Inaugural Chair, Division of Laboratory Medicine Promotions Committee, 1995 - 1997
Member, Advisory Committee to the Search Committee for the Division Head, Division of Laboratory Medicine, 1995
Member, Institutional Physicians Referral Service Scientific Review Committee, 1995 - 1998
Member, Institutional Committee on Graduate Education and Research, 1994 - 1995
Member, IRGC/BRG (Institutional Research Grant Committee/Biomedical Research Grant) Committee, 1989 - 1991
Honors & Awards
| 2021 | Recipient, the William Randolph Hearst Foundation Faculty Achievement Award in Education, University of Texas MD Anderson Cancer Center |
| 2021 - 2024 | University of Texas System Shine Academy Member, The University of Texas System Kenneth I Shine Academy of Health Science Educaiton |
| 2017 | Program in Human and Molecular Genetics Distinguished Faculty Award, Graduate School of Biomedical Sciences Program in Human and Molecular Genetics |
| 2017 | Barbara H. Bowman Award for Outstanding Contributions to Genetics in the State of Texas, Texas Genetics Society |
| 2012 | Texas Genetics Society Distinguished Service Award, Texas Genetics Society |
| 2002 - 2005 | University of Texas Health Science Center Honors Convocation Recipient, The University of Texas Health Science Center |
| 2002 | Renewal of GSBS Regular Membership With Highest Commendation, The University of Texas Graduate School of Biomedical Science |
| 1992 - 2001 | The University of Texas Graduate School of Biomedical Sciences Dean’s Excellence Award, The University of Texas Graduate School of Biomedical Sciences at Houston, TX |
| 1987 | Basil O'Connor March of Dimes Scholar, March of Dimes |
| 1981 | Co-recipient, Mike Hogg Award for the Most Outstanding Paper in Oncological Sciences, The University of Texas Health Science Center |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2014. Boot Camp. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2014. Human and Molecular Genetics Program Annual Symposium. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2013. Seminar. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2011. Mentor. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2010. Presentation. Conference. Molecular Cytogenetics Facility. Houston, TX, US.
- 2010. Retreat. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2010. Panel Member. Conference. Kinkaid High School. Houston, TX, US.
- 2009. Grand Rounds Presentation. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2008. Seminar. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2008. Seminar. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2006. Seminar. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2004. Invited Speaker. Conference. Turner Syndrome Society. Houston, TX, US.
- 2004. Invited Speaker. Conference. Leadership Texas, The University of Texas MD Anderson Cancer Center Site Visit. Houston, TX, US.
- 2003. DNA. Conference. Sylvan Rodriguez Elementary School. Houston, TX, US.
- 1998. Speaker for Career Day. Conference. Lanier Middle School, Houston Independent School District. Houston, TX, US.
- 1998. Keynote Address. Conference. Texas Undergraduate Education in Biological Sciences Society. Houston, TX, US.
- 1996. Lecture on Genetics. Conference. Kincaid High School. Houston, TX, US.
- 1996. In-service Presentation for a Continuing Education in Clinical Chemistry Lecture. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 1996. Presentation to the M.D. Anderson Cancer Center External Advisory Committee on Research. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 1995. Invited Speaker for Friends of Volunteer Organization for M.D. Anderson, Volunteers Endowment for Patient Support. Conference. Friends of the Volunteer Organization for M.D. Anderson, Volunteers Endowment for Patient Support. Houston, TX, US.
Regional Presentations
- 2017. Keynote Address. Conference. Texas Genetics Society. College Station, TX, US.
- 2014. Retreat. Conference. The University of Texas MD Anderson Cancer Center. Camp Allen, TX, US.
- 1995. Presentation to the Fort Bend Chamber of Commerce Leadership 2000 Class. Conference. Fort Bend Chamber of Commerce. Sugar Land, TX, US.
- 1995. Presentation to Donors of the American Cancer Society. Conference. American Cancer Society, US.
- 1988. Presentation to March of Dimes Advisory Council. Conference. March of Dimes. San Antonio, TX, US.
National Presentations
- 2019. Panel Discussant. Conference. AUREO Real Estate Conference, hosted by MD Anderson, discussion on research ongoing through the history of MD Anderson. Houston, TX, US.
- 2019. Invited Participant. Conference. National Cancer Institute Early Detection Research Network (EDRN) 11th Annual Workshop. Bethesda, MD, US.
- 2018. Presentation. Invited. Pancreatic Cancer Detection Consortium. Washington,, DC, US.
- 2018. Invited Participant from UT System. Invited. Stanford Chief Wellness Course. san Francisco, CA, US.
- 2018. Invited Participant, Stanford Chief Wellness Officer Course. Conference. Executive Vice Chancellor Ray Greenberg. Palo Alto, CA, US.
- 2015. Presentation. Conference. CPRIT Cancer Conference. Austin, TX, US.
- 2015. Presentation. Invited. Aspen Cancer Conference. Aspen, CO, US.
- 2015. Presentation. Invited. National Cancer Institute Early Detection Research Network, US.
- 2014. Presentation. Invited. National Cancer Institute Early Detection Research Network, US.
- 2014. Presentation. Invited. Aspen Cancer Conference. Aspen, CO, US.
- 2014. Presentation. Invited. National Cancer Institute Early Detection Research Network, US.
- 2013. Presentation. Invited. National Cancer Institute Early Detection Research Network, US.
- 2013. Presentation. Invited. National Cancer Institute Early Detection Research Network, US.
- 2011. 7th Annual Scientific Workshop. Invited. NCI Early Detection Research Network. Washington DC, US.
- 2011. Panel Discussion. Invited. 22nd Steering Committee Meeting, NCI Early Detection Research Network. Los Angeles, CA, US.
- 2010. Steering Committee Meeting. Invited. National Cancer Institute Early Detection Research Network. Washington, DC, US.
- 2010. Steering Committee Meeting. Invited. National Cancer Institute Early Detection Research Network. Tempe, AZ, US.
- 2009. GI Collaborative Group (Conference Call). Invited. National Cancer Institute Early Detection Resarch Network, US.
- 2009. Poster Presentation. Invited. NCI Translates Meeting. Washington, DC, US.
- 2008. Steering Committee Meeting. Invited. National Cancer Institute Early Detection Research Network. Bethesda, MD, US.
- 2008. Steering Committee Meeting. Invited. National Cancer Institute Early Detection Research Network. Washington, DC, US.
- 2008. Steering Committee Meeting. Invited. National Cancer Institute Early Detection Research Network. Seattle, WA, US.
- 2008. Collaborative Group Meeting. Invited. National Cancer Institute Early Detection Reseach Network. Seattle, WA, US.
- 2008. Steering Committee Meeting. Invited. National Cancer Institute Early Detection Research Network. Bethesda, MD, US.
- 2006. Pancreatic Collaborative Group Meeting. Invited. National Cancer Institute Early Detection Research Network. Denver, CO, US.
- 2005. Steering Committee Meeting. Invited. National Cancer Institute Early Detection Research Network. Bethesda, US.
- 2004. Steering Committee Meeting. Invited. National Cancer Institute Early Detection Research Network. Bethesda, US.
- 2002. Renal Cell Carcinoma. Invited. American Urological Association Summer Research Conference. Houston, TX, US.
- 1995. Advances in the Biology and Therapy of Renal Cell Carcinoma. Invited. Third Annual Genitourinary Oncology Conference, The University of Texas M. D. Anderson Cancer Center. Houston, TX, US.
- 1995. Platform Presentation. Invited. American Society of Human Genetics. Minneapolis, MN, US.
- 1995. Keynote Lecture. Invited. American Association of Clinical Scientists. Houston, TX, US.
- 1994. Keynote Speaker. Invited. Texas Genetics Society. Dallas, TX, US.
- 1993. Cell Death in Cancer. Invited. American Association for Cancer Research Special Conference. Chatham, MA, US.
- 1992. Negative Growth Controls. Invited. ICN/UCLA Conference, US.
- 1991. Platform Presentation. Invited. American Association for Cancer Research Annual Meeting. Houston, TX, US.
- 1991. Physical Mapping for the Human Genome Project. Invited. NIH Workshop, US.
- 1990. Negative Growth Controls. Invited. ICN/UCLA Conference, US.
- 1989. Molecular Genetics. Invited. Gordon Conference, US.
International Presentations
- 2016. Presentation. Conference. Gordon Research Conference, Mammary Gland in Development and Cancer. Lucca, IT.
- 2016. Presentation. Conference. Workshop for Innovative Cancer Biomarker Development. Tokyo, JP.
- 2016. Poster Presentation. Conference. Gordon Conference on Mammary Gland in Development and Cancer. Lucca, IT.
- 2015. Presentation. Invited. Workshop for Innovative Cancer Biomarker Development. Tokyo, JP.
- 2013. Keynote Address (Invited, Declined). Invited. Turkish Society of Medical Genetics. Istanbul, TR.
- 2004. Predictive Oncology. Invited. 7th International Symposium. Nice, FR.
- 2000. VHL Care in the New Millennium. Invited. Fourth International Symposium on von Hippel-Lindau, Mayo Clinic. Rochester, US.
- 1995. Platform Presentation. Invited. American Association for Cancer Research. Toronto, CA.
- 1995. Human Chromosome 3. Invited. International Congress. Minneapolis, US.
- 1994. Human Chromosome 3. Invited. Human Chromosome 3 International Congress. Ann Arbor, US.
Formal Peers
- 2015. Poster Presentation. Invited, US.
- 2015. Seminar. Invited. Tokoyo, JP.
- 2014. The DEAR Tumor Suppressor Gene. Invited, US.
- 2010. . Invited. San Antonio, TX, US.
- 2009. Program in Human and Molecuar Genetics Symposium. Invited. Houston, TX, US.
- 2003. Institute for Molecular Medicine, Texas A&M Univer. Invited. Houston, US.
- 2002. Texas A&M University. Invited. College Station, TX, US.
- 2002. Department of Pathology, University of Texas South. Invited. Dallas, TX, US.
- 2000. Functional Evidence for a VHL-Independent Pathway to Tumorigenesis in the Kidney. Invited. Frederick, MD, US.
- 2000. Functional Evidence for a VHL-Independent Pathway to Tumorigenesis in the Kidney”. Invited. Bethesda, MD, US.
Grant & Contract Support
| Date: | 2023 - 2026 |
| Title: | "DEAR1 as a Critical Regulator of Epithelial-Mesenchymal Plasticity to Stratify Triple Negative Breast Cancers for Precision Therapy using an Organoid Model" |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | RP230255 |
| Date: | 2018 - 2023 |
| Title: | Circulating Biomarkers and Imaging for Early Detection of Pancreatic Cancer - Subrata Sen contact MPI; Ann Killary, MPI |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | UO1CA214263-05 |
| Date: | 2018 - 2023 |
| Title: | Translational Genomics and Precision Medicine Training Grant -contact MPI Ann Killary; MPI Ignacio Wistuba |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | T32 CA217789-05 |
| Date: | 2018 - 2021 |
| Title: | Blood-Based Biomarkers for the Early Detection of Pancreatic Cancer - Ann Killary contact MPI; Subrata Sen, MPI |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | RP180607 |
| Date: | 2015 - 2018 |
| Title: | DEAR1 as a novel regulator of cell polarity and progression |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | PI |
| ID: | RP150403 |
| Date: | 2014 - 2016 |
| Title: | MDACC PANCREATIC MOONSHOT |
| Funding Source: | MDACC |
| Role: | Co-I |
| ID: | MDACC PANCREATIC MOONSHOT |
| Date: | 2012 - 2014 |
| Title: | Subcontract from the NCI Early Detection Research Network |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | 2 U24 CA115091-06 |
| Date: | 2012 - 2014 |
| Title: | DEAR1 Loss of Function Involved in Progression of DCIS to Invasive Breast Cancer |
| Funding Source: | Department of Defense (DOD) |
| Role: | Co-I |
| Date: | 2011 - 2012 |
| Title: | On the role of DEAR1 in the regulation of the breast tumor microenvironment |
| Funding Source: | MRC |
| Role: | PI |
| Date: | 2010 - 2011 |
| Title: | On the Role of the Novel Polarity Regulator/Tumor Suppressor DEAR1 in the Regulation of the TGFβ Pathway and Epithelial-Mesenchymal-Transition in Pancreatic Cancer |
| Funding Source: | G. S. Hogan Foundation |
| Role: | PI |
| Date: | 2010 - 2012 |
| Title: | Subcontract with Sanford Stass, MD, University of Maryland Standardization of blood assays for early detection biomarkers of pancreatic ductal adenocarcinoma.-Ann Killary contact MPI, Subrata Sen, MPI |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 2 U24 CA115091-06 |
| Date: | 2010 - 2015 |
| Title: | Biomarkers for the early detection of pancreatic cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2010 - 2017 |
| Title: | Biomarkers for the Early Detection of Pancreatic Cancer Ann Killary contact MPI; Subrata Sen MPI |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 2U01 CA111302-10 (PI) |
| Date: | 2008 - 2010 |
| Title: | Functional mapping and identification of a prostate cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | U01 CA117452 |
| Date: | 2004 - 2009 |
| Title: | Biomarkers for the Early Detection of Pancreatic Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | UO1 CA111202-5 |
| Date: | 2003 - 2003 |
| Title: | Characterization of CAR-1, a candidate tumor suppressor gene in breast cancer |
| Funding Source: | Department of Defense (DOD) |
| Role: | PI |
| ID: | DAMD17-02-1-0453-1 |
| Date: | 2003 - 2003 |
| Title: | A Stepwise Mechanism for Malignant Conversion in VHL Tumorigenesis |
| Funding Source: | W. M. KECK CENTER FOR CANCER GENE THERAPY DEVELOPMENT AWARD |
| Role: | PI |
| Date: | 2002 - 2005 |
| Title: | Characterization of CAR-1, a Candidate Tumor Suppressor Gene in Breast Cancer |
| Funding Source: | U.S. Army (DOD) |
| Role: | PI |
| ID: | DOD DAMD17-02-1-0453-1 |
| Date: | 2002 - 2005 |
| Title: | Charactization of CAR-1, a candidate tumor suppressor gene in breast cancer |
| Funding Source: | DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP) |
| Role: | PI |
| ID: | DAMD17-02-1-0453-1 |
| Date: | 2002 - 2004 |
| Title: | Functional Mapping and Identification of a Prostate Cancer Tumor Suppressor Gene within Chromosome 3p |
| Funding Source: | U.S. Army (DOD) |
| Role: | PI |
| ID: | DOD DAMD17-02-1-0095-1 |
| Date: | 2002 - 2004 |
| Title: | Characterization of CAR-1, a candidate tumor suppressor gene in breast cancer |
| Funding Source: | DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP) |
| Role: | PI |
| ID: | DAMD17-02-1-453-1 |
| Date: | 2001 - 2002 |
| Title: | Characterization of a Candidate Tumor Suppressor Gene for Colorectal Carcinoma |
| Funding Source: | NCCRA AWARD |
| Role: | Project Investigator |
| Date: | 2001 - 2002 |
| Title: | Chromosome 3 p12 Gene Discovery |
| Funding Source: | KECK GENE THERAPY AWARD |
| Role: | PI |
| Date: | 2000 - 2001 |
| Title: | Postdoctoral Fellowships-Dawn Chandler |
| Funding Source: | LADIES AUXILIARY TO VETERANS OF FOREIGN WARS |
| Role: | Mentor to Dr. Dawn Chandler |
| Date: | 2000 - 2001 |
| Title: | A Molecular Profile of Renal Cell Carcinoma |
| Funding Source: | BUSINESS AND PROFESSIONAL WOMEN ASSOCIATION AWARD |
| Role: | PI |
| Date: | 2000 - 2002 |
| Title: | Molecular Characterization of a Novel RING Finger Protein Implicated in Neoplasia |
| Funding Source: | TEXAS ADVANCED RES. PROGRAM |
| Role: | PI |
Selected Publications
Peer-Reviewed Articles
- Enriquez, JS, Chu, Y, Pudakalakatti, S, Hsieh KL, Salmon, D, Dutta, P, Zacharias, Millward, NZ, Lurie, E, Millward, S, McAllister, FM, Maitra, A, Sen, S, Killary, A, Zhang, J, Jiang, X, Bhattacharya PK, Shams, S. Hyperpolarized Magnetic Resonance and Artificial Intelligence: Frontiers of Imaging in Pancreatic Cancer. MIR Med Inform, 2021. e-Pub 2021.
- Dittmar RL, Liu S, Tai MC, Rajapakshe K, Huang Y, Longton G, DeCapite C, Hurd MW, Paris PL, Kirkwood KS, Coarfa C, Maitra A, Brand RE, Killary AM, Sen S. Plasma MicroRNA Biomarkers in Limited Volume Samples for Detection of Early Stage Pancreatic Cancer. Cancer Prev Res (Phila), 2021. e-Pub 2021.
- Balasenthil S, Huang Y, Liu S, Marsh T, Chen J, Stass SA, KuKuruga D, Brand R, Chen N, Frazier ML, LeeJJ, Srivastava S, Sen S, Killary AM. A Plasma Biomarker Panel to Identify Surgically Resectable Early Stage Pancreatic Cancer. J Natl Cancer Inst 109(8), 2017. e-Pub 2017. PMID: 28376184.
- Chen J, Wu X, Huang Y, Chen W, Brand RE, Killary AM, Sen S, Frazier ML. Identification of genetic variants predictive of early onset pancreatic cancer through a population science analysis of functional genomic datasets. Oncotarget 7(35):56480-56490, 2016. e-Pub 2016. PMID: 27486767.
- Wang J, Paris PL, Chen J, Ngo V, Yao H, Frazier ML, Killary AM, Liu CG, Liang H, Mathy C, Bondada S, Kirkwood K, Sen S. Next generation sequencing of pancreatic cyst fluid microRNAs from low grade-benign and high grade-invasive lesions. Cancer Lett 356(2 Pt B):404-9, 2015. e-Pub 2015. PMID: 25304377.
- Haab BB, Huang Y, Balasenthil S, Partyka K, Tang H, Anderson M, Allen P, Sasson A, Zeh H, Kaul K, Kletter D, Ge S, Bern M, Kwon R, Blasutig I, Srivastava S, Frazier ML, Sen S, Hollingsworth MA, Rinaudo JA, Killary AM, Brand RE. Definitive Characterization of CA 19-9 in Resectable Pancreatic Cancer Using a Reference Set of Serum and Plasma Specimens. PLoS One 10(10):e0139049, 2015. e-Pub 2015. PMID: 26431551.
- Quintás-Cardama A, Post SM, Solis LM, Xiong S, Yang P, Chen N, Wistuba II, Killary AM, Lozano G. Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer. J Pathol 234(1):108-19, 2014. e-Pub 2014. PMID: 24890125.
- Liu Q, Chen J, Wang J, Amos C, Killary AM, Sen S, Wei C, Frazier ML. Putative tumor suppressor gene SEL1L was downregulated by aberrantly upregulated hsa-mir-155 in human pancreatic ductal adenocarcinoma. Mol Carcinog 53(9):711-21, 2014. e-Pub 2014. PMID: 23661430.
- Wang J, Raimondo M, Guha S, Chen J, Diao L, Dong X, Wallace MB, Killary AM, Frazier ML, Woodward TA, Wang J, Sen S. Circulating microRNAs in Pancreatic Juice as Candidate Biomarkers of Pancreatic Cancer. J Cancer 5(8):696-705, 2014. e-Pub 2014. PMID: 25258651.
- Chen N, Balasenthil S, Reuther J, Frayna A, Wang Y, Chandler DS, Abruzzo LV, Rashid A, Rodriguez J, Lozano G, Cao Y, Lokken E, Chen J, Frazier ML, Sahin AA, Wistuba II, Sen S, Lott ST, Killary AM. DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition. Cancer Discov 3(10):1172-89, 2013. e-Pub 2013. PMID: 23838884.
- Gambaro K, Quinn MC, Wojnarowicz PM, Arcand SL, de Ladurantaye M, Barrès V, Ripeau JS, Killary AM, Davis EC, Lavoie J, Provencher DM, Mes-Masson AM, Chevrette M, Tonin PN. VGLL3 expression is associated with a tumor suppressor phenotype in epithelial ovarian cancer. Mol Oncol 7(3):513-30, 2013. e-Pub 2013. PMID: 23415753.
- Chen NY, Balasenthil S, Reuther J, Frayna A, Wang Y, Chandler DS, Abruzzo LV, Rashid A, Rodriquez J, Lozano G, Cao Y, Lokken E, Chen J, Frazier ML, Sahin AA, Wistuba II, Sen S, Lott ST, Killary AM. DEAR1 is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGFB-Driven Epithelial-Mesenchymal Transition. Cancer Disc 3(10):1172-89, 2013. e-Pub 2013.
- Liu Q, Chen J, Mai B, Amos C, Killary AM, Sen S, Wei C, Frazier ML. A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in caucasians. Mol Carcinog 51(5):433-8, 2012. e-Pub 2012. PMID: 21656579.
- Chen J, Wu X, Pande M, Amos CI, Killary AM, Sen S, Frazier ML. Susceptibility locus for lung cancer at 15q25.1 is not associated with risk of pancreatic cancer. Pancreas 40(6):872-5, 2011. e-Pub 2011. PMID: 21697764.
- Balasenthil S, Chen N, Lott ST, Chen J, Carter J, Grizzle WE, Frazier ML, Sen S, Killary AM. A migration signature and plasma biomarker panel for pancreatic adenocarcinoma. Cancer Prev Res (Phila) 4(1):137-49, 2011. e-Pub 2011. PMID: 21071578.
- Chen M, Gu J, Delclos GL, Killary AM, Fan Z, Hildebrandt MA, Chamberlain RM, Grossman HB, Dinney CP, Wu X. Genetic variations of the PI3K-AKT-mTOR pathway and clinical outcome in muscle invasive and metastatic bladder cancer patients. Carcinogenesis 31(8):1387-91, 2010. e-Pub 2010. PMID: 20530239.
- Chen J, Amos CI, Merriman KW, Wei Q, Sen S, Killary AM, Frazier ML. Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic Whites: a case-control study. Pancreas 39(1):1-4, 2010. e-Pub 2010. PMID: 19910837.
- Wang J, Chen J, Chang P, LeBlanc A, Li D, Abbruzzesse JL, Frazier ML, Killary AM, Sen S. MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease. Cancer Prev Res (Phila) 2(9):807-13, 2009. e-Pub 2009. PMID: 19723895.
- Lott ST, Chen N, Chandler DS, Yang Q, Wang L, Rodriguez M, Xie H, Balasenthil S, Buchholz TA, Sahin AA, Chaung K, Zhang B, Olufemi SE, Chen J, Adams H, Band V, El-Naggar AK, Frazier ML, Keyomarsi K, Hunt KK, Sen S, Haffty B, Hewitt SM, Krahe R, Killary AM. DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer. PLoS Med 6(5):e1000068, 2009. e-Pub 2009. PMID: 19536326.
- Chen J, Li D, Killary AM, Sen S, Amos CI, Evans DB, Abbruzzese JL, Frazier ML. Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation. Ann Surg Oncol 16(2):431-9, 2009. e-Pub 2009. PMID: 19020940.
- Chen J, Killary AM, Sen S, Amos CI, Evans DB, Abbruzzese JL, Frazier ML. Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer. Cancer Lett 272(1):32-9, 2008. e-Pub 2008. PMID: 18694622.
- Sasai K, Parant JM, Brandt ME, Carter J, Adams HP, Stass SA, Killary AM, Katayama H, Sen S. Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality. Oncogene 27(29):4122-7, 2008. e-Pub 2008. PMID: 18345035.
- Zhang K, Lott ST, Jin L, Killary AM. Fine mapping of the NRC-1 tumor suppressor locus within chromosome 3p12. Biochem Biophys Res Commun 360(3):531-8, 2007. e-Pub 2007. PMID: 17624313.
- Chen J, Li D, Wei C, Sen S, Killary AM, Amos CI, Evans DB, Abbruzzese JL, Frazier ML. Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians. Clin Cancer Res 13(10):3100-4, 2007. e-Pub 2007. PMID: 17505013.
- Hu M, Nicolson GL, Trent JC, Yu D, Zhang L, Lang A, Killary A, Ellis LM, Bucana CD, Pollock RE. Characterization of 11 human sarcoma cell strains: evaluation of cytogenetics, tumorigenicity, metastasis, and production of angiogenic factors. Cancer 95(7):1569-76, 2002. e-Pub 2002. PMID: 12237927.
- Lott ST, Chandler DS, Curley SA, Foster CJ, El-Naggar A, Frazier M, Strong LC, Lovell M, Killary AM. High frequency loss of heterozygosity in von Hippel-Lindau (VHL)-associated and sporadic pancreatic islet cell tumors: evidence for a stepwise mechanism for malignant conversion in VHL tumorigenesis. Cancer Res 62(7):1952-5, 2002. e-Pub 2002. PMID: 11929809.
- Padalecki SS, Johnson-Pais TL, Killary AM, Leach RJ. Chromosome 18 suppresses the tumorigenicity of prostate cancer cells. Genes Chromosomes Cancer 30(3):221-9, 2001. e-Pub 2001. PMID: 11170278.
- Kruzelock RP, Cuevas BD, Wiener JR, Xu FJ, Yu Y, Cabeza-Arvelaiz Y, Pershouse M, Lovell MM, Killary AM, Mills GB, Bast RC. Functional evidence for an ovarian cancer tumor suppressor gene on chromosome 22 by microcell-mediated chromosome transfer. Oncogene 19(54):6277-85, 2000. e-Pub 2000. PMID: 11175342.
- el-Naggar AK, Lovell M, Callender DL, Ordonez NG, Killary AM. Cytogenetic analysis of a primary salivary gland myoepithelioma. Cancer Genet Cytogenet 113(1):49-53, 1999. e-Pub 1999. PMID: 10459346.
- Lovell M, Lott ST, Wong P, El-Naggar A, Tucker S, Killary AM. The genetic locus NRC-1 within chromosome 3p12 mediates tumor suppression in renal cell carcinoma independently of histological type, tumor microenvironment, and VHL mutation. Cancer Res 59(9):2182-9, 1999. e-Pub 1999. PMID: 10232606.
- el-Naggar AK, Lovell M, Callender DL, Killary AM. Limited nonrandom chromosomal aberrations in a recurrent adenoid cystic carcinoma of the parotid gland. Cancer Genet Cytogenet 109(1):66-9, 1999. e-Pub 1999. PMID: 9973962.
- Lott ST, Lovell M, Naylor SL, Killary AM. Physical and functional mapping of a tumor suppressor locus for renal cell carcinoma within chromosome 3p12. Cancer Res 58(16):3533-7, 1998. e-Pub 1998. PMID: 9721855.
- Curley SA, Lott ST, Luca JW, Frazier ML, Killary AM. Surgical decision-making affected by clinical and genetic screening of a novel kindred with von Hippel-Lindau disease and pancreatic islet cell tumors. Ann Surg 227(2):229-35, 1998. e-Pub 1998. PMID: 9488521.
- el-Naggar AK, Lovell M, Ordonez NG, Killary AM. Multiple unrelated translocations in a metastatic epimyoepithelial carcinoma of the parotid gland. Cancer Genet Cytogenet 100(2):155-8, 1998. e-Pub 1998. PMID: 9428361.
- Pershouse MA, Ligon AH, Pereira-Smith OM, Killary AM, Yung WK, Steck PA. Suppression of transformed phenotype and tumorigenicity after transfer of chromosome 4 into U251 human glioma cells. Genes Chromosomes Cancer 20(3):260-7, 1997. e-Pub 1997. PMID: 9365833.
- Todd MC, Xiang RH, Garcia DK, Kerbacher KE, Moore SL, Hensel CH, Liu P, Siciliano MJ, Kok K, van den Berg A, Veldhuis P, Buys CH, Killary AM, Naylor SL. An 80 Kb P1 clone from chromosome 3p21.3 suppresses tumor growth in vivo. Oncogene 13(11):2387-96, 1996. e-Pub 1996. PMID: 8957080.
- el-Naggar AK, Lovell M, Killary AM, Batsakis JG. Genotypic characterization of a primary mucoepidermoid carcinoma of the parotid gland by cytogenetic, fluorescence in situ hybridization, and DNA ploidy analysis. Cancer Genet Cytogenet 89(1):38-43, 1996. e-Pub 1996. PMID: 8689608.
- Sanchez Y, Lovell M, Marin MC, Wong PE, Wolf-Ledbetter ME, McDonnell TJ, Killary AM. Tumor suppression and apoptosis of human prostate carcinoma mediated by a genetic locus within human chromosome 10pter-q11. Proc Natl Acad Sci U S A 93(6):2551-6, 1996. e-Pub 1996. PMID: 8637912.
- Killary AM, Lott ST. Production of Microcell Hybrids. Methods 9(1):3-11, 1996. e-Pub 1996. PMID: 9245337.
- Naylor SL, Carritt B, Boileau C, Beroud C, Alexander C, Allderdice P, Alimov A, Ashworth T, Bonifas J, Bugert P, Buys CH, Chipperfield MA, Deng G, Drabkin H, Gemmill RM, Grompe M, Joensuu T, Jonasdottir A, Gizatullin R, Krols L, Leach RJ, Lott ST, Killary A, Martinsson T, Messiaen L. Report of the sixth international workshop on human chromosome 3 mapping 1995. Cytogenet Cell Genet 72(4):255-70, 1996. e-Pub 1996. PMID: 8641130.
- Ichikawa T, Nihei N, Kuramochi H, Kawana Y, Killary AM, Rinker-SchaefferCW, Barrett JC, Isaacs JT, Kugoh H, Oshimura M, Shimazaki J. Metastasis suppressor genes for prostate cancer. Prostate Suppl 6:31-5, 1996. e-Pub 1996. PMID: 8630227.
- Nihei N, Ichikawa T, Kawana Y, Kuramochi H, Kugo H, Oshimura M, Killary AM, Rinker-Schaeffer CW, Barrett JC, Isaacs JT. Localization of metastasis suppressor gene(s) for rat prostatic cancer to the long arm of human chromosome 10. Genes Chromosomes Cancer 14(2):112-9, 1995. e-Pub 1995. PMID: 8527392.
- Yulug IG, Killary AM, Sandhu AK, Athwal RS, Fox M, Fisher EM. Gene expression in response to retinoic acid in novel human chromosome 21 monochromosomal cell hybrids. Somat Cell Mol Genet 21(5):357-65, 1995. e-Pub 1995. PMID: 8619133.
- Woloshin P, Song K, Degnin C, Killary AM, Goldhamer DJ, Sassoon D, Thayer MJ. MSX1 inhibits myoD expression in fibroblast x 10T1/2 cell hybrids. Cell 82(4):611-20, 1995. e-Pub 1995. PMID: 7664340.
- Killary AM, Fournier RE. Microcell fusion. Methods Enzymol 254:133-52, 1995. e-Pub 1995. PMID: 8531682.
- el-Naggar AK, Lovell M, Killary A, Batsakis JG. Trisomy 5 as the sole chromosomal abnormality in a primary mucoepidermoid carcinoma of the minor salivary gland. Cancer Genet Cytogenet 76(2):96-9, 1994. e-Pub 1994. PMID: 7923075.
- Sanchez Y, el-Naggar A, Pathak S, Killary AM. A tumor suppressor locus within 3p14-p12 mediates rapid cell death of renal cell carcinoma in vivo. Proc Natl Acad Sci U S A 91(8):3383-7, 1994. e-Pub 1994. PMID: 8159756.
- Pershouse MA, Stubblefield E, Hadi A, Killary AM, Yung WK, Steck PA. Analysis of the functional role of chromosome 10 loss in human glioblastomas. Cancer Res 53(20):5043-50, 1993. e-Pub 1993. PMID: 8104691.
- Daly MC, Xiang RH, Buchhagen D, Hensel CH, Garcia DK, Killary AM, Minna JD, Naylor SL. A homozygous deletion on chromosome 3 in a small cell lung cancer cell line correlates with a region of tumor suppressor activity. Oncogene 8(7):1721-9, 1993. e-Pub 1993. PMID: 8390035.
- Killary AM, Wolf ME, Giambernardi TA, Naylor SL. Definition of a tumor suppressor gene within human chromosome 3p21-p22. Proc Natl Acad Sci U S A 89(22):10877-81, 1992. e-Pub 1992. PMID: 1438292.
- Sleister HM, Mills KA, Blackwell SE, Killary AM, Murray JC, Malone RE. Construction of a human chromosome 4 YAC pool and analysis of artificial chromosome stability. Nucleic Acids Res 20(13):3419-25, 1992. e-Pub 1992. PMID: 1630913.
- Glisson BS, Killary AM, Merta P, Ross WE, Siciliano J, Siciliano MJ. Dissociation of cytotoxicity and DNA cleavage activity induced by topoisomerase II-reactive intercalating agents in hamster-human somatic cell hybrids. Cancer Chemother Pharmacol 31(2):131-8, 1992. e-Pub 1992. PMID: 1333369.
- Ning Y, Weber JL, Killary AM, Ledbetter DH, Smith JR, Pereira-Smith OM. Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4. Proc Natl Acad Sci U S A 88(13):5635-9, 1991. e-Pub 1991. PMID: 2062841.
- Tait JF, Frankenberry DA, Miao CH, Killary AM, Adler DA, Disteche CM. Chromosomal localization of the human annexin III (ANX3) gene. Genomics 10(2):441-8, 1991. e-Pub 1991. PMID: 1830024.
- Weber JL, Kwitek AE, May PE, Killary AM. Dinucleotide repeat polymorphism at the D4S174 locus. Nucleic Acids Res 18(15):4636, 1990. e-Pub 1990. PMID: 2388858.
- Weber JL, May PE, Patterson D, Drabkin H, Killary AM. Dinucleotide repeat polymorphism at the D3S196 locus. Nucleic Acids Res 18(15):4635, 1990. e-Pub 1990. PMID: 2388857.
- de Lange T, Shiue L, Myers RM, Cox DR, Naylor SL, Killery AM, Varmus HE. Structure and variability of human chromosome ends. Mol Cell Biol 10(2):518-527, 1990. e-Pub 1990. PMID: 2300052.
- Sakaguchi AY, Lalley PA, Choudhury GG, Martinez L, Han ES, Killary AM, Naylor SL, Wang LM. Mouse melanoma growth stimulatory activity gene (Mgsa) is polymorphic and syntenic with the W, patch, rumpwhite, and recessive spotting loci on chromosome 5. Genomics 5(3):629-32, 1989. e-Pub 1989. PMID: 2575589.
- Hsieh CL, Lee WH, Lee EY, Killary AM, Lalley PA, Naylor SL. Assignment of retinoblastoma susceptibility gene to mouse chromosome 14. Somat Cell Mol Genet 15(5):461-4, 1989. e-Pub 1989. PMID: 2781416.
- Smith A, Lalley PA, Killary AM, Ghosh-Choudhury G, Wang LM, Han ES, Martinez L, Naylor SL, Sakaguchi AY. Sigje, a member of the small inducible gene family that includes platelet factor 4 and melanoma growth stimulatory activity, is on mouse chromosome 11. Cytogenet Cell Genet 52(3-4):194-6, 1989. e-Pub 1989. PMID: 2576529.
- Wang LM, Killary AM, Fang XE, Parriott SK, Lalley PA, Bell GI, Sakaguchi AY. Chromosome assignment of mouse insulin, colony stimulating factor 1, and low-density lipoprotein receptors. Genomics 3(2):172-6, 1988. e-Pub 1988. PMID: 3066742.
- Rajput B, Marshall A, Killary AM, Lalley PA, Naylor SL, Belin D, Rickles RJ, Strickland S. Chromosomal assignments of genes for tissue plasminogen activator and urokinase in mouse. Somat Cell Mol Genet 13(5):581-6, 1987. e-Pub 1987. PMID: 2821634.
- Lugo TG, Handelin B, Killary AM, Housman DE, Fournier RE. Isolation of microcell hybrid clones containing retroviral vector insertions into specific human chromosomes. Mol Cell Biol 7(8):2814-20, 1987. e-Pub 1987. PMID: 2823107.
- Meinkoth J, Killary AM, Fournier RE, Wahl GM. Unstable and stable CAD gene amplification: importance of flanking sequences and nuclear environment in gene amplification. Mol Cell Biol 7(4):1415-24, 1987. e-Pub 1987. PMID: 3600632.
- Killary AM, Leach RJ, Moran RG, Fournier RE. Assignment of genes encoding dihydrofolate reductase and hexosaminidase B to mus musculus chromosome 13. Somat Cell Mol Genet 12(6):641-8, 1986. e-Pub 1986. PMID: 2947337.
- Peterson TC, Killary AM, Fournier RE. Chromosomal assignment and trans regulation of the tyrosine aminotransferase structural gene in hepatoma hybrid cells. Mol Cell Biol 5(9):2491-4, 1985. e-Pub 1985. PMID: 2874483.
- Killary AM, Fournier RE. An isozyme-specific selective system for the recovery of mammalian cells deficient in hepatic alcohol dehydrogenase activity. Exp Cell Res 154(2):442-53, 1984. e-Pub 1984. PMID: 6383854.
- Killary AM, Fournier RE. A genetic analysis of extinction: trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells. Cell 38(2):523-34, 1984. e-Pub 1984. PMID: 6147198.
- Killary AM, Lugo TG, Fournier RE. Isolation of thymidine kinase-deficient rat hepatoma cells by selection with bromodeoxyuridine, Hoechst 33258, and visible light. Biochem Genet 22(3-4):201-13, 1984. e-Pub 1984. PMID: 6203516.
- McNeill CA, Brown RL. Genetic manipulation by means of microcell-mediated transfer of normal human chromosomes into recipient mouse cells. Proc Natl Acad Sci U S A 77(9):5394-8, 1980. e-Pub 1980. PMID: 7001478.
- Le, UQ, Chen, N, Balasenthil, S, Lurie, E, Yang, F, Liu, S, Rubin, L, Sahin, AA, Wistuba, II, Killary A, AM. Tumor suppressor DEAR1 regulates mammary epithelial cell fate and predicts early onset and metastasis in Triple Negative Breast Cancer. Scientific Reports.
Invited Articles
- Chen N, Balasenthil S, Reuther J, Killary AM. a novel tumor suppressor that regulates cell polarity and epithelial plasticity. Cancer Res 74(20), 2014. e-Pub 2014. PMID: 25261235.
Review Articles
- Chen N, Balasenthil S, Reuther J, Killary AM. DEAR1, a novel tumor suppressor that regulates cell polarity and epithelial plasticity. Cancer Res 74(20):5683-9, 2014. e-Pub 2014. PMID: 25261235.
- el-Naggar AK, Lovell M, Callender DL, Ordonez NG, Killary AM. Concurrent cytogenetic, interphase fluorescence in situ hybridization and DNA flow cytometric analyses of a carcinoma ex-pleomorphic adenoma of parotid gland. Cancer Genet Cytogenet 107(2):132-6, 1998. e-Pub 1998. PMID: 9844608.
- El-Naggar AK, Lovell M, Killary AM, Clayman GL, Batsakis JG. A mucoepidermoid carcinoma of minor salivary gland with t(11;19)(q21;p13.1) as the only karyotypic abnormality. Cancer Genet Cytogenet 87(1):29-33, 1996. e-Pub 1996. PMID: 8646736.
Book Chapters
- Killary AM Lott ST. Production of microcell hybrids. In: Methods, A Companion to Methods in Enzymology. Academic Press Inc, 3 - 11, 1996.
- Killary AM, Fournier REK. Microcell Fusion. In: Methods in Enzymology. Academic Press Inc, 133 - 152, 1995.
- Killary AM, Lott ST, Sanchez Y. Functional studies to identify tumor suppressor genes. In: Methods: A Companion to Methods in Enzymology. Academic Press Inc, 1995.
Patents
- Beaudet DA, McNeill Killary DA. Haploid Protein Test. Patent Number: United States Patent 6.8,18,401.
- McNeill Killary DA, Lott DS, Chandler DD. The Tumor Suppressor CAR1/DEAR1: Divisional US Patent Issued. Patent Number: United States Patent 7,169,384.
Patient Reviews
CV information above last modified July 25, 2025