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      Anthony P. Conley Image

      Anthony P. Conley, MD

      Department of Sarcoma Medical Oncology, Division of Cancer Medicine

      Present Title & Affiliation

      Dual/Joint/Adjunct Appointment

      Professor, Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas

      Education & Training

      Degree-Granting Education

      2004The University of Texas, Medical Branch, Galveston, Texas, US, MD
      2000The University of Texas, Pan American, Edinburg, Texas, US, Biology, BS

      Postgraduate Training

      2010-2011Sarcoma Fellowship, Advanced Scholars Program/Willie Tichenor Sarcoma Fellowship, Sarcoma Research, University of Texas MD Anderson Cancer Center, Houston, Texas
      2007-2010Clinical Fellowship, Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
      2005-2007Clinical Residency, Internal Medicine, The University of Texas Health Science Center, Houston, Texas
      2004-2005Clinical Internship, Internal Medicine, The University of Texas Health Science Center, Houston, Texas

      Licenses & Certifications

      2025Georgia Composite Medical Board
      2025Mississippi State Board of Medical Licensure
      2025Oklahoma State Board of Medical Licensure
      2025Louisiana State Board of Medical Examiners
      2025Arizona Medical Board
      2025Washington State Department of Health
      2025Tennessee Board of Medical Examiners
      2025Alabama Board of Medical Examiners
      2021Florida Board of Medicine
      2011American Board of Internal Medicine, Medical Oncology
      2007Texas Medical Board
      2007American Board of Internal Medicine

      Experience & Service

      Faculty Academic Appointments

      Associate Professor, Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2025

      Assistant Professor, Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2019

      Assistant Professor, University of South Florida Morsani College of Medicine, Tampa, FL, 2011 - 2012

      Instructor, Sarcoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2011

      Administrative Appointments/Responsibilities

      Section Chief, Sarcoma Medical Oncology, UT MD Anderson Cancer Center, 2025 - Present

      Assistant Member, Sarcoma, Moffitt Cancer Center, Tampa, FL, 2012 - 2012

      Department Lead, Sarcoma Medical Oncology, Moffitt Cancer Center, Tampa, FL, 2011 - 2012

      Other Professional Positions

      Consultant, Ipsen Biopharmaceuticals, 2024

      Consultant, Inhibrx, Inc, San Diego, CA, 2023 - Present

      Consultant, Aadi Biosciences, 2022

      Member, Outreach Committee, Connective Tissue Oncology Society (CTOS), Houston, 2022 - Present

      Member, Data Safety Monitoring Board, CAR-T Solid Tumor Program, University of Pennsylvania, Pennsylvania, 2021 - Present

      Scientific Advisory Board, Deciphera Pharmaceuticals, Houston, TX, 2021 - 2024

      Consultant, MD Anderson Physician Network, Houston, TX, 2019 - Present

      Scientific Advisory Board, Eli Lilly Pharmaceuticals, Houston, TX, 2018

      Scientific Advisory Board, Ignyta Pharmaceuticals, Houston, TX, 2017

      Member, Early Therapeutics & Rare Cancers Committee, Southwestern Oncology Group (SWOG), Houston, TX, 2016 - Present

      Consultant, Nektar Pharmaceuticals, San Francisco, CA, 2016

      Consultant, EMD Serano, Rockland, MA, 2015

      Member, MD Anderson Site Advisory Panel, Center Trials Support Unit (CTSU), National Cancer Institute, Houston, TX, 2015 - 2018

      Consultant, Novartis, East Hanover, NJ, 2015 - 2015

      Consultant, EMD Serono, Rockland, MA, 2015

      Member, Sarcoma Survivorship Committee, Southwestern Oncology Group (SWOG), Houston, TX, 2015 - 2017

      Consultant, Novartis, New Jersey, 2011

      Consultant, Novartis, New Jersey, 2011 - 2014

      Consultant, Sanofi Aventis, New Jersey, 2011

      Intramural Institutional Committee Activities

      Vice Chair, Medical Practice Committee, UTMD Anderson Cancer Center, 2025 - Present

      Extramural Institutional Committee Activities

      Member, AJCC V9 Bone Sarcoma Expert Panel, The University of Texas MD Anderson Cancer Center, 2025 - Present

      Guest Clinician & Investigator, NIH Pediatric Chordoma Clinic, NIH, 2025 - Present

      Member-Elect, Executive Committee of the Faculty Senate, The University of Texas MD Anderson Cancer Center, 2024

      Member, Medical Charts, The University of Texas MD Anderson Cancer Center, 2022 - Present

      Member, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2021 - Present

      Associate Member, Institutional Review Board 2, The University of Texas MD Anderson Cancer Center, 2021 - 2024

      Member, Pharmacy & Therapeutics Committee, University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017 - 2019

      Member, Medical Practice Committee, University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2017 - Present

      Ad hoc medical reviewer, CRC, University of Texas MD Anderson, The University of Texas MD Anderson Cancer Center, 2016 - Present

      Co-Chairman, Rhabdomyosarcoma Working Group, The University of Texas MD Anderson Cancer Center, 2014 - Present

      Member, Mid Level Provider (MLP) Working Group, The University of Texas MD Anderson Cancer Center, 2014 - Present

      Medical Oncology Lead, Chondrosarcoma Working Group, The University of Texas MD Anderson Cancer Center, 2012 - Present

      Member, Personalized Clinical Trials Group, The University of Texas MD Anderson Cancer Center, 2012 - 2012

      Member, Graduate Medical Education Committee, The University of Texas MD Anderson Cancer Center, 2007 - 2010

      Editorial Activities

      Member of Editorial Review Board, The Sarcoma Journal, 2018 - 2020

      Review Editor, Frontiers in Immunology, 2017 - Present

      Honors & Awards

      2024 - PresentTop Doctor, Texas Monthly
      2023Top 10% National Performers, CGCAHPS
      2023Top Doctor of Houston in Castle Connolly
      2022Texas Super Doctors
      2022Top Performer, 1% Nationally Patient Care, Clinical & Group Consumer Assessment of Healthcare Providers & Systems
      2018Texas Rising Stars, Texas Monthly 06/2018 issue
      2018Top 10% Performers, CGCAHPS
      2011Physician of the Year Nominee, Moffitt Cancer Center
      2010ASCO Cancer Foundation Young Investigator Award, ASCO
      2007Michelle Miller Rozzell Academic Achievement Award, The University of Texas, Houston
      2006 - 2007Outstanding Resident of the Year Award, The University of Texas Health Science Center
      2005Award of Appreciation - Summer Internship for Undergraduate Students in Biomedical Engineering, The University of Texas, MD Anderson Cancer Center

      Professional Memberships

      Chondrosarcoma Foundation

      2022 - Present

      European Society of Medical Oncology

      2020 - Present

      2015 QuadW-AACR Meeting

      2015

      Society of Immunotherapy of Cancer

      2015 - Present

      Sarcoma Alliance for Research Collaboration

      2011 - Present

      American Association for Cancer Research

      2009 - Present

      Connective Tissue Oncology Society

      2009 - Present

      Sarcoma Foundation of America

      2009 - Present

      ASCO/AACR Workshop

      2009 - 2009

      American Society of Clinical Oncology

      2008 - Present

      Texas Medical Association

      2004 - Present

      Harris County Medical Society

      2004 - Present

      American College of Physicians

      2004 - 2007

      United Latin American Medical Students

      2000 - 2004

      American Medical Association

      2000 - 2004

      Alpha Kappa Kappa Fraternity (UTMB)

      2000 - 2002

      Selected Presentations & Talks

      Local Presentations

      1. 2014. Sarcomas Integrative Oncology Education Series. Conference. UTMD Anderson Cancer Center. Houston, TX, US.
      2. 2010. Targeted Therapy of Giant Cell Tumor of Bone. Conference. MD Anderson Cancer Center. Houston, TX, US.

      Regional Presentations

      1. 2021. Overview of Chondrosarcoma – Biological Landscape and Clinical Implications. Conference. UT MD Anderson Cancer Center. Houston, US.
      2. 2020. Medical Management of Advanced/Metastatic Chordomas. Conference. UT MD Anderson Cancer Center. Houston, US.
      3. 2018. Update on the Biology & Treatment of Soft Tissue Sarcomas, Liposarcomas, and Leiomyosarcomas. Conference. UT MD Anderson Cancer Center, US.
      4. 2018. Immunotherapy for Sarcoma: Are we ready?. Conference. UT MD Anderson Cancer Center, US.
      5. 2011. Soft Tissue Sarcoma. Conference. 2nd Annual Florida Oncology Symposium. Florida, US.
      6. 2011. Soft Tissue Sarcoma: Breaking Tradition for Advanced Metastatic Disease. Conference. Watson Clinic, US.
      7. 2009. GIST Information Support & Therapy Summit. Conference. GIST Support International, US.

      National Presentations

      1. 2020. Patient-reported Outcomes (PROs) From Patients (Pts) with NTRK Fusion-Positive (NTRK-fp) Solid Tumours Receiving Entrectinib in the Global Phase 2 STARTRK-2 Study. Invited. Virtual ESMO Congress 2020 Meeting, US.
      2. 2017. Systemic Therapies for Chordoma. Invited. Chordoma Foundation/MD Anderson Cancer Center Workshop. Houston, TX, US.
      3. 2014. PA/ARNP/Allied Health Scientific Session/Osteosarcoma and Chrondrosarcoma. Invited. Musculoskeletal Tissue Society (MSTS). Tampa, FL, US.
      4. 2012. Scientific Session/Immunotherapy in Sarcomas. Invited. Musculoskeletal Tissue Society (MSTS). Tampa, FL, US.
      5. 2012. PA/ARNP/Allied Health Scientific Session/Sarcoma Medical Oncology. Invited. Musculoskeletal Tissue Society (MSTS). Houston, TX, US.

      International Presentations

      1. 2025. Primary Localized Chordoma Consensus Guidelines Working Group. Panelist. Milan, IT.
      2. 2025. Potential Targeted Molecular/Immunotherapies in Clival Chordoma. 34th Annual Meeting & 9th World Congress, US.
      3. 2024. Adjuvant Therapy Options & Updates - Chordoma. Sacro-Pelvic Tumor Study Group Meeting, US.
      4. 2024. Adjuvant Therapy Options & Updates - Chondrosarcoma. Sacro-Pelvic Tumor Study Group Meeting, US.
      5. 2023. A Phase 2 Trial of Cetuximab for Patients with Advanced/Metastatic Chordoma. Invited. Chordoma International Workshop. Boston, US.
      6. 2021. Oral Abstract Sarcoma Session. Invited. Scientific Program Committee, US.
      7. 2018. Immunotherapy in Soft Tissue Sarcoma. Invited. Sociedad Mexicana de Oncologia 36th National Congress in Oncology, MX.
      8. 2018. Advanced Disease. Invited. Chordoma Foundation/International Chordoma Research Workshop. Boston, US.
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      Grant & Contract Support

      Date: 2025 - Present
      Title:A Phase 1B Study of Brachyury-specific T-Cell Therapy for the Treatment of Patients with Advanced or Refractory Chordoma
      Funding Source:Cancer Research Institute (CRI)
      Role:Co-PI
      Date: 2020 - 2022
      Title:Identification of TCR Targets for Chordoma
      Funding Source:Cancer Research Institute
      Role:Co-PI
      ID:CR13233
      Date: 2020 - 2026
      Title:Texas Experimental Cancer Therapeutics Network - TEX CTN
      Funding Source:NIH/NCI
      Role:Collaborator
      ID:RFA-CA-19-007
      Date: 2016 - 2019
      Title:Early Therapeutics Development with Phase II Emphasis
      Funding Source:NIH/NCI
      Role:Collaborator
      ID:HHSN261201100039C
      Date: 2010 - 2011
      Title:Differential MicroRNA Expression and Positron Emission Tomography in Gastrointestinal Stromal Tumors (GIST) After Treatment with Imatinib
      Funding Source:American Society of Clinical Oncology (ASCO)
      Role:PI
      Date: 2009
      Title:MicroRNA Regulation of Aberrant KIT Signaling in Gastrointestinal Stromal Tumors (GIST)
      Funding Source:GIST Cancer Research
      Role:Co-PI

      Selected Publications

      Invited Articles

      1. El Beaino M, Roszik J, Livingston JA, Wang WL, Lazar AJ, Amini B, Subbiah V, Lewis V, Conley AP. Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology. Curr Oncol Rep 20(5):37, 2018. e-Pub 2018. PMID: 29582189.

      Review Articles

      1. Groisberg R, Roszik J, Conley A, Patel SR, Subbiah V. The Role of Next-Generation Sequencing in Sarcomas: Evolution From Light Microscope to Molecular Microscope. Curr Oncol Rep 19(12):78, 2017. e-Pub 2017. PMID: 29030741.

      Professional Educational Materials

      1. Collaborator O. Personalized Cancer Therapy Website, 2014.

      Abstracts

      1. Soewito, S, Lin, HY, Zoghbi, M, Pan, C, Young, P, Araujo, DM, Conley, AP, Livingston, JA, Ludwig, JA, Nakazawa, MS, Ratan, R, Ravi, V, Somaiah, N, Zarzour, MA, Patel, S, Meyer, LA, Soliman, PT, Lyu, H, Nassif, EF, Denu, RA. Doxorubicin-based chemotherapy vs gemcitabine/docetaxel in uterine leiomyosarcoma (ULMS) 43, 2025. e-Pub 2025.
      2. Lacuna KP, Ingham M, Chen L, Das B, Lee SM, Ge L, Druta M, Conley AP, Keohan ML, Agulnik M, Burgess MA, Chalmers AW, D'Amato GZ, Powers B, Seetharam M, Siontis BL, Pelosof LC, Van Tine BA, Schwartz GK, Weiss MC. Correlative results from NCI CTEP/ETCTN 10330: A phase 2 study of belinostat with SGI-110 (guadecitabine) or ASTX727 (decitabine/cedazuridine) for advanced conventional chondrosarcoma (cCS). 2024 Annual ASCO Meeting.
      3. Gingrich A, Beird H, Segura RL, Denu R, Nakazawa M, Ratan R, Livingston J, Zarzour MA, Conley AP, Somaiah N, Araujo DM, Patel S, Roland CL, Futreal A, Lazar AJ, Keung EZ, Nassif Haddad EF, Initiative Team RT, Team PM. Immune infiltrate analysis to reveal distinct immune classes for leiomyosarcomas. 2024 ASCO Annual Meeting.
      4. Conley AP, Ravi V, Roland CL, Reid TR, Larson C, Caroen S, Williams JA, Oronsky B, Stirn M, Abrouk N, Burbano E, Kennedy LB. Phase 1/2 study of the TGF-β-trap-enhanced oncolytic adenovirus, AdAPT-001, plus an immune checkpoint inhibitor for patients with immune refractory cancers. 2024 ASCO Annual Meeting.
      5. Munnangi P, King BL, Chiang Y, Conley AP, Araujo DM, Livingston J, Ludwig JA, Nakazawa M, Nassif Haddad EF, Ravi V, Ratan R, Zarzour MA, Patel S, Torres KE, Somaiah N. Systemic therapy in NF-1 associated malignant peripheral nerve sheath tumors (MPNST). 2024 ASCO Annual Meeting.
      6. Nash A, Ratan R, Somaiah N, Conley AP, Lewis VO, Wang WL, Lin HY, Daw NC, Gill JB, Harrison DJ, Gorlick RG, Patel S, Livingston JA. Harmonizing cancer care delivery for AYAs with osteosarcoma: Comparison of pediatric and medical oncology approaches in a single center. 2024 ASCO Annual Meeting.
      7. Denu RA, Segura RL, Farooqi AS, Ingram D, Wani KM, Cai Y, Torres KE, Keung E, Roland CL, Somaiah N, Ying H, Huse JT, Rai K, Conley AP, Patel S, Wang WL, Lazar AJ, Haddad-Nassif EF. Impact of ATRX loss on survival and immune microenvironment in multiple sarcoma subtypes. 2024 ASCO Annual Meeting.
      8. Gounder MM, Rosen E, Parikh AR, Conley AP, Hong DS, Sheth S, Mai N, Sgroe E, Mitchell R, Picard R, Brail LH, Cote GM. Preliminary results from FLAGSHP-1: A phase 1 study of ERAS-601 as a monotherapy or in combination with cetuximab in patients (pts) previously treated for advanced chordoma. 2024 Annual ASCO Meeting.
      9. Wu X, Ledbetter D, de Almeida RA, Singh S, Conley A, Wang W, Lazar A, Lang F, Gomez-Manzano C, Fueyo J, Alvarez-Breckenridge C. EXTH-67. ONCOLYTIC ADENOVIRAL INFECTION OF CHORDOMA ACHIEVES TREATMENT EFFICACY THROUGH IMMUNOGENIC CELL DEATH AND TUMOR MICROENVIRONMENT ALTERATION. Society for Neuro-Oncology 26(Supplement 8):viii252.
      10. Thirasastr P, Raj R, Vilson RS, Joseph C, Lin H, Munnangi P, Torres KE, Araujo DM, Nassif Haddad EF, A Zarzour MA, Iyer AV, Pemmanda M, Nakazawa MS, Ludwig JA, Benjamin RS, Conley AP, Livingston A, Patel S, Ratan R, Ravi V, Somaiah N. OUTCOMES OF LATER-LINES SYSTEMIC THERAPIES IN MALIGNANT PERIPHERAL NERVE SHEATH TUMORS (MPNST). Connective Tissue Oncology Society.
      11. Torrado C, Nassif Haddad EF, Nakazawa MS, Araujo DM, Bird JE, Dumbrava EE, Rodon J, Fu S, Hong DS, Lewis VO, Livingston A, Meric-Bernstam F, Patel S, Piha-Paul SA, Ratan R, Ravi V, Somaiah N, Tsimberidou AM, Naing A, Ludwig J, Zarzour MA, Yap TA, Conley AP. NOVEL THERAPEUTICS AND SURROGATE ENDPOINTS IN CHONDROSARCOMA: A RETROSPECTIVE ANALYSIS FROM A PHASE 1 UNIT. Connective Tissue Oncology Society.
      12. Wannaphut C, Thirasastr P, Nakazawa MS, Araujo DM, Benjamin RS, Conley AP, Livingston A, Ludwig JA, Patel S, Ratan R, Ravi V, A Zarzour MA, Nassif Haddad EF, Somaiah N. Treatment Outcomes of Gemcitabine and DOCETAXEL in Patients with Clear Cell Sarcoma (CCS) OR GASTROINTESTINAL NEUROECTODERMAL TUMOR (GNET): A CASE SERIES. CTOS.
      13. Grachev D, Ivanov D, Kushnarev V, Yong ST, Kotlov N, Chernyshov K, Bagaev A, Fowler NH, Conley AP, Cote GM, Chawla SP. Transcriptomic analysis of novel tumor suppressor gene fusions in bone sarcomas. 2024 ASCO Annual Meeting.
      14. Conley AP, Reid T, Larson C, Oronsky B, Caroen S, Stirn M, Burbano E, Abrouk N, Roland CL, Williams J, Kennedy LB. Improved clinical outcomes in patients received treatment beyond tumor progression with AdAPT-001 +/- a checkpoint inhibitor 84.
      15. Conley AP, Ferry-Galow, Fino KK, Coyne G, Moore N, Sharon E, Burgess M, Chen J, Davis EJ, Merriam P, Razak AR, Vine Tine B, Foster JC, Takebe N, Rosenberger CL, Doroshow JH, Chen AP, Parchment RE. Atezolizumab clinical trial biopsies reveal varied immune landscapes in clear cell sarcoma and chondrosarcoma. AACR Annual Meeting.

      Book Chapters

      1. Livingston JA, Conley AP, Ravi V, Patel SR. In: Chapter 42: Soft tissue and bone sarcomas, The MD Anderson Manual of Medical Oncology, 3rd edition. McGraw Hill, 2022.
      2. Subbiah V, Roszik J, Conley A. In: Handbook of Targeted Cancer Therapy and Immunotherapy. Wolters Kluwer, 2018.
      3. Conley AP, Ravi V, Patel S. Targeted Therapy in Solid Tumors: Sarcomas. In: Targeted Therapy in Translational in Cancer Research. John Wiley & Sons, Inc, 2016.
      4. Livingston JA, Conley A, Ravi V, Patel S. The MD Anderson Manual of Medical Oncology. In: Soft Tissue and Bone Sarcomas. Third. McGraw Hill Medical, 2015.
      5. Subbiah V, Conley A. In: Sarcoma Chapter. Handbook of Targeted Cancer Therapy. Philadelphia, PA: Wolters Kluwer, 2014.
      6. Henderson-Jackson E, Conley A, Bui MM. Molecular Pathology of bone and soft tissue neoplasms and potential targets for novel therapy. In: Cancer Growth and Progression. In: Chapter 13. Springer, 2012.
      7. Conley, AP, Park MS, Trent J, Patel S. Chapter 40: Soft-Tissue and Bone Sarcomas. In: The MD Anderson Manual of Medical Oncology. McGraw Hill Medical, 2010.
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      Patient Reviews


      CV information above last modified September 17, 2026

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