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Bradley M. Broom, Ph.D.

Present Title & Affiliation

Primary Appointment

Professor, Department of Bioinformatics and Computational Biology, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston

Bio Statement

Bradley M. Broom, Ph.D., is an Associate Professor in the Department of Bioinformatics and Computational Biology at MD Anderson Cancer Center.

Dr. Broom is a computer scientist, receiving his Ph.D. from the University of Queensland (Australia) in 1988.


Access additional information regarding Dr. Broom's research and professional activities.

Research Interests

Computational Bioinformatics

Office Address

The University of Texas MD Anderson Cancer Center
1400 Pressler Street
Unit Number: 1410
Houston, TX 77030
Room Number: FCT4.4.5006
Phone: 713-792-2617
Fax: 713-563-4242

Education & Training

Degree-Granting Education

1988 The University of Queensland, Queensland, Australia, PHD, Computer Science
1983 The University of Queensland, Queensland, Australia, BS, First Class Honours in Computer Science
1982 The University of Queensland, Queensland, Australia, BS, Computer Science


Academic Appointments

Associate Professor, Statistics, Texas A&M, College Station, TX, 6/2007-2012
Associate Professor, Department of Bioinformatics and Computational Biology, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/2004-8/2011
Research Scientist, Computer Science, Rice University, Houston, TX, 2/1999-8/2004
Associate Professor, Data Communications, Queensland University of Technology, Brisbane, Australia, 1/1994-1/1999
Research Fellow/Lecturer, Computer Science, Australian National University, Canberra, Australia, 1/1990-12/1993
Research Officer/Senior Research Officer, Computer Science, University of Queensland, St. Lucia, Australia, 1/1988-12/1989

Honors and Awards

2008 Sharon K. Martin Award, The University of Texas MD Anderson Cancer Center
2001 Joint best paper in the cluster computing category, 2001 IEEE International Symposium on Cluster Computing and the Grid
1984-1987 Commonwealth Postgraduate Research Award

Professional Memberships

Association for Computing Machinery
Member, 2006-present
Member, 1983-1996
Australian Unix Users Group
Executive Committee Member, Queensland Chapter, 1996-1998
Australian UNIX Users Group, Queensland, Australia
Program Committee, 1996-1998
Australian Unix Users Group
Member, 1995-1999
Institute of Electrical and Electronic Engineers
Member, 1990-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Broom BM, Rinsurongkawong W, Pusztai L, Do KA. Building networks with microarray data. Methods Mol Biol 620:315-43, 2010. PMID: 20652510.
2. Sanga S, Broom BM, Cristini V, Edgerton ME. Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family. BMC Med Genomics 2(1):59, 2009. e-Pub 9/11/2009. PMCID: PMC2753593.
3. Koch M, Broom BM, Subramanian D. Learning robust cell signalling models from high throughput proteomic data. Int. J. Bioinformatics Research and Applications 5(3):241-253, 2009.
4. Deus HF, Stanislaus R, Veiga DF, Behrens C, Wistuba II, Minna JD, Garner HR, Swisher SG, Roth JA, Correa AM, Broom B, Coombes K, Chang A, Vogel LH, Almeida JS. A Semantic Web management model for integrative biomedical informatics. PLoS ONE 3(8):e2946, 2008. PMCID: PMC2491554.
5. Deus HF, Stanislaus R, Behrens C, Wistuba I, Minna JD, Garner HR, Swisher SG, Roth J, Correa A, Broom B, Coombes K, Almeida JS. Data Driven Semantic Integration of Translational Lung Cancer Research at MDAnderson Cancer Center. AMIA Annu Symp Proc:927, 2008. PMID: 18999102.
6. Broom BM, McDonnell TJ, Subramanian D. Predicting altered pathways using extendable scaffolds. Int J Bioinform Res Appl 2(1):3-18, 2006. PMID: 18048150.
7. Kennedy K, Broom B, Chauhan A, Fowler R, Garvin J, Koelbel C, McCosh C, Mellor-Crummey J. Telescoping Languages: A System for Automatic Generation of Domain Languages. Proceedings of the IEEE 93:387-408, 2005.
8. Kennedy K, Broom B, Cooper K, Dongarra J, Fowler R, Gannon D, Johnson L, Mellor-Crummey J, Torczan L. Telescoping languages: A strategy for automatic generation of scientific, problem-solving systems from annotated libraries. Journal of Parallel and Distributed Computing 61:1803-26, 2003.
9. Broom B, Fowler R, Kennedy K. A telescope-ready domain-specific I/O library for irregular block-structured applications. Future Generation Computer Systems 18:449-60, 2002.
10. Mellor-Crummey J, Adve V, Broom B, Chavarria-Miranda D, Fowler R, Jin G, Kennedy K, Yi Q. Advanced optimization strategies in the Rice dHPF compiler. Currency and Computation: Practice and Experience 14:741-67, 2002.
11. Do K, Broom B, Wang X. Importance bootstrap resampling for proportional hazards regression. Communications in Statistics–Theory and Methods 30:2173-88, 2001.
12. Do K, Broom B, Kuhnert P, Duffy D, Todorov A, Treloar S, Martin N.. Genetic analysis of the age at menopause by using estimating equations and Bayesian random effects models. Stat Med 19:1217-35, 5/2000. PMID: 10797518.
13. Ashley P, Broom B, Vaudenwauver M. An implementation of a secure version of NFS including REBAC. Australian Computer Journal, 1999.
14. Wood A, Do K-A, Broom B. Sequential linearization of empirical likelihood constraints with application to U-statistics. Journal of Computational and Graphical Statistics 5:365-385, 1996.
15. Broom B. A synchronous file server for distributed file systems. Australian Computer Science Communications B:501-12, 2/1993.
16. Vickers T, Broom B. On teaching a Unix window interface in first year. Australian Computer Science Communications, 2/1993.
17. Welsh J, Broom B, Kiong D. A design rationale for a language-based editor. Software–Practice & Experience 21:923-948, 1991.
18. Broom B, Welsh J. Another approach to literate programming. Australian Computer Science Communications:257-68, 2/1988.
19. Broom B. A distributed syntax-directed editor. Australian Computer Science Communications:116-25, 2/1987.
20. Broom B, Welsh J. Detail compression techniques for interactive program display. Australian Computer Science Communications:83-93, 2/1986.
Other Articles
1. Ashley P, Broom B. System administration: Securing networked applications with SESAME. Linux Journal, 1998.
2. Ashley P, Broom B. A survey of secure multi-domain distributed architectures. Technical Report FIT-TR-97-08, Queensland University of Technology, Faculty of Information Technology, Brisbane, Australia, 1997.
3. Ashley P, Broom B. An implementation of the SESAME security architecture for Linux. AUUG Queensland Technical Conference, Brisbane, Australia, 1997.
4. Broom B, Welsh J. Display techniques for language-based editors. Technical Report 198, University of Queensland, Department of Computer Science, Brisbane, Australia, 1991.
5. Broom B. User mode per-process name spaces for the AP1000 file system. Technical Report TR-CS-93-08. Australian National University, Department of Computer Science, Brisbane, Australia, 1991.
6. Broom B. Aspects of Interactive Program Display, Ph.D. thesis. University of Queensland, Department of Computer Science, 1987.


1. Ahmed A A, Le X, Liao W, Grandjean G, Bartholomeusz G, Broom B, Lu Z, Bast Jr. RC. Kinase regulated microtubule stabilization correlates with ovarian cancer paclitaxel response in a target specific siRNA kinome screen. Minisymposium Mechanisms of Drug Targeting Cell Cycle Controls, 2009 AACR Meeting, Denver CO(3869), 4/2009.
2. Koch, M, Broom, B, Subramanian, D. A Search-Based Approach for Bayesian Inference of the T-cell Signaling Network. Biotechnology and Bioinformatics Symposium 2007, Colorado Springs, CO, 10/2007.

Book Chapters

1. Jeong J, Vannucci M, Do K-A, Broom BM, Kim S, Sha N, Tadesse M, Yan K, Pusztai L. Gene selection for the identification of biomarkers in high-throughput data. In: Bayesian Modeling in Bioinformatics. Ed(s) DK Dey, S Ghosh, B Mallick. Chapman & Hall, 2010.
2. Broom BM, Do K-A. Statistical methods for biomarker discovery using mass spectrometry. In: Statistical Advances in the Biomedical Sciences: State of the Art and Future Directions. Ed(s) Atanu Biswas, Sujay Datta, Jason Fine, Mark Segal. Wiley: New Jersey, 465-86, 2008.
3. Broom B, Subramanian D. Computational Methods for Learning Bayesian Networks from High - Throughout Biological Data. In: Bayesian Inference for Gene Expression and Proteomics. Ed(s) Do K-A, Mueller P, Vannucci M. Cambridge University Press, 385-400, 2006.
4. Broom, B, Fowler, R, Kennedy, K, Koelbel, C, Paleczny, M. Compiler support for out-of-core arrays on parallel machines. In: Scalable Input/Output. MIT Press, 161-180, 2003.
5. Do K-A, Broom B, Wen S. GeneClust. In: The analysis of gene expression data: Methods and software. Ed(s) Parmigiani G, Garrett E, Irizarry RA, Zeger SL. Springer: New York, 342-61, 2003. ISBN: 0-387-95577-1.


1. Proceedings. Walsh D, Bailey P, Broom B. Message domains: Efficient support for layered message passing software, Proceedings of the Third Fujitsu-ANU CAP Workshop, Kawasaki, Japan, November 1992.
2. Proceedings. Mutisya G, Broom B. Distributed caching algorithms for the AP1000, Proceedings of the Third Fujitsu-ANU CAP Workshop, Kawasaki, Japan, November 1992.
3. Proceedings. Broom B, Welsh J, Wildman L. A literate rigorous program case study, Proceedings of the Fifth Australian Software Engineering Conference, 321-326, Sydney, Australia, May 1990.
4. Proceedings. Broom B, Welsh J, Wildman L. UQ2: a mulitlingual document editor, Proceedings of the Fifth Australian Software Engineering Conference, 289-294, Sydney, Australia, May 1990.
5. Proceedings. Broom B, Cohen R. Acacia: a distributed, parallel file system for the CAP-II, Proceedings of the First Fujitsu-ANU CAP Workshop, Kawasaki, Japan, November 1990.
6. Proceedings. Broom B. Implementation and performance of the Acacia file system, Proceedings of the Second Fujutsu-ANU CAP Workshop, Canberra, Australia, November 1991.
7. Proceedings. Lautenbauch B, Broom B. A parallel file system for the AP 1000, Proceedings of the Third Fujitsu-ANU CAP Workshop, Kawasaki, Japan, November 1992.
8. Proceedings. Ashley P, Vandenwauver M, Broom B. A Uniform approach to securing Unix applications using SESAME, Boyd C, Dawson E., editors, Proceedings of the Third Australian Conference on Information Security and Privacy, number 1438, Lecture Notes, Computer Science, 24-35, Brisbane, Australia, July 1998.
9. Proceedings. Broom B, Ashley P. A SESAME Environment in AUUG Conference Proceedings: Open Systems- The Common Thread, September 1998.

Last updated: 6/3/2013