Cielito C. Reyes-Gibby, Dr. PH
Department of Emergency Medicine, Division of Internal Medicine
About Dr. Reyes-Gibby
Dr. Reyes-Gibby is a Professor with Tenure in the Department of Emergency Medicine. She has a dual appointment in the Department of Biostatistics.
Dr. Reyes-Gibby is a population scientist, and the focus of her research is on the application of classical and molecular epidemiology approaches to understanding the complex interaction among clinical, epidemiological and biological/genetic factors on the occurrence and persistence of cancer-related symptoms and toxicities of cancer treatment. Early in her career, she received a Career Development Award from the National Cancer Institute (NCI) that enabled her to pursue advanced training in molecular and statistical genetic methods of analyses. Her research is considered innovative, as it bridges the fields of basic and clinical research to better understand the biological mechanisms underlying cancer-related symptoms. Since 2004, she has been awarded several grants as Principal Investigator by the National Institutes of Health (NIH) that aim to identify biological markers of risk for severe and persistent cancer-related symptoms and toxicities of treatment including neuropathic pain and oral mucositis. She also received foundation grants to pursue clinical research on pain and opioid misuse risk. Most recently, she received a grant to develop a disposition index for immune-related adverse events from immune-checkpoint inhibitor therapy.
She served as Founding Chair of the Genetics and Pain Special Interest Group of the American Pain Society and serves as Vice Chair of the Scientific Advisory Committee of Comprehensive Oncologic Emergencies Research Network (CONCERN), a multi-institutional network of departments of emergency medicine sponsored by the NCI that aims to improve the understanding of oncologic emergencies. She served as Chair of the Research Committee in the Division of Internal Medicine at MD Anderson. She is on the editorial boards of her specialty journals and a member of the Interdisciplinary Clinical Care in Specialty Care Settings Study Section at the NIH. She also served as a panelist for a NIH initiative for identifying innovative and ground breaking scientific approaches to the study of the genetics of chronic pain conditions. She is the 2016 recipient of the Provost Distinguished Faculty Mentor Award at MD Anderson.
Present Title & Affiliation
Primary Appointment
Professor with Term Tenure, Department of Emergency Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston
Dual/Joint/Adjunct Appointment
Professor, Department of Biostatistics, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston
Research Interests
Pain and Cancer-Related Symptoms Molecular Epidemiology Neuropathic Pain
Education & Training
Degree-Granting Education
| 1998 | The University of Texas School of Public Health, Houston, TX, USA, DPH, Public Health |
Postgraduate Training
| 2024-2024 | Continuing Education, Neurobiology of Attachment, The National Institute for the Clinical Application of Behavioral Science, Storss, CT |
| 2024-2024 | Continuing Education, Treating Trauma Master Series, National Institute for the Clinical Application of Behavioral Medicine, Storrs, CT |
| 2022-2022 | Continuing Education, Nano Course for Cardio-oncology, University of Texas School of Biological Sciences, Houston, TX |
| 2022-2022 | Workshop, Machine Learning, University of Texas MD Anderson Cancer Center, Houston, TX |
| 2019-2019 | Leadership, Harvard Executive Program, Cambridge, MA |
| 2017-2017 | Workshop, Ingenuity Pathway Analysis, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2016-2017 | Leadership, Faculty Leadership Academy, Cohort 16, University of Texas MD Anderson Cancer Center, Houston, TX |
| 2013-2013 | Workshop, Statistical Modeling Workshop for Genetics of Addiction, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2012-2012 | Continuing Education, Statistical Modeling of the Genetics of Addiction, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2008-2008 | Continuing Education, Statistical Analyses for Genetic Epidemiology, Case Western Reserve University, Cleveland, OH |
| 2007-2007 | Continuing Education, SNP Analyses Workshop, National Institute of Environmental and Health Sciences, Houston, TX |
| 2006-2006 | Continuing Education, Longitudinal Modeling, University of Texas School of Public Health, Houston, TX |
| 2006-2006 | Continuing Education, Molecular Epidemiology, University of Texas School of Biological Sciences, Houston, TX |
| 2005-2005 | Fellow, Molecular Genetics in Research, Health and Society, National Institutes of Health and Georgetown University, Bethesda, MD |
| 2004-2004 | Continuing Education, Analyses of Longitudinal Data from Epidemiologic Studies, University of Michigan School of Public Health, Ann Arbor, MI |
| 2004-2004 | Continuing Education, Genetics in Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI |
| 2004-2004 | Continuing Education, Molecular Biology for Genetic Epidemiology, Johns Hopkins University, Baltimore, MD |
| 2004-2004 | Continuing Education, Genetic Epidemiology in Populations, Johns Hopkins University, Baltimore, MD |
| 1999-1999 | Postdoctoral Trainee, Department of Health Services Organization, The University of Texas Graduate School of Public Health, Houston, TX |
Experience & Service
Administrative Appointments/Responsibilities
Chair, Research Committee, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2021
Co-Chair, Research Committee, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - 2019
Director, Program in Oncologic Emergency Medicine, Department of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2018
Other Appointments/Responsibilities
Disease-specific Executive Committee, National Comprehensive Cancer Network (NCCN), Baltimore, MD, 2000 - 2002
Honors & Awards
| 2005 | Fellowship, Summer Genetics Institute, National Institute of Health Research |
| 2004 | Career Development Award, National Cancer Institute |
Selected Publications
Peer-Reviewed Articles
- Zhang L, San Valentin EMD, John TM, Jenq RR, Do KA, Hanna EY, Peterson CB, Reyes-Gibby CC. Influence of oral microbiome on longitudinal patterns of oral mucositis severity in patients with squamous cell carcinoma of the head and neck. Cancer 130(1):150-161, 2024. e-Pub 2023. PMID: 37688396.
- Reyes-Gibby CC, Qdaisat A, Ferrarotto R, Fadol A, Bischof JJ, Coyne CJ, Lipe DN, Hanna EY, Shete S, Abe JI, Yeung SJ. Cardiovascular events after cancer immunotherapy as oncologic emergencies: Analyses of 610 head and neck cancer patients treated with immune checkpoint inhibitors. Head Neck. e-Pub 2023. PMID: 38151809.
- San Valentin EMD, Do KA, Yeung SJ, Reyes-Gibby CC. Attempts to Understand Oral Mucositis in Head and Neck Cancer Patients through Omics Studies: A Narrative Review. Int J Mol Sci 24(23), 2023. e-Pub 2023. PMID: 38069314.
- Dagher H, Chaftari AM, Subbiah IM, Malek AE, Jiang Y, Lamie P, Granwehr B, John T, Yepez E, Borjan J, Reyes-Gibby C, Flores M, Khawaja F, Pande M, Ali N, Rojo R, Karp DD, Chaftari P, Hachem R, Raad II. Long COVID in cancer patients: preponderance of symptoms in majority of patients over long time period. Elife 12, 2023. e-Pub 2023. PMID: 36748905.
- Jain A, Casanova D, Padilla AV, Paniagua Bojorges A, Kotla S, Ko KA, Samanthapudi VSK, Chau K, Nguyen MTH, Wen J, Hernandez Gonzalez SL, Rodgers SP, Olmsted-Davis EA, Hamilton DJ, Reyes-Gibby C, Yeung SJ, Cooke JP, Herrmann J, Chini EN, Xu X, Yusuf SW, Yoshimoto M, Lorenzi PL, Hobbs B, Krishnan S, Koutroumpakis E, Palaskas NL, Wang G, Deswal A, Lin SH, Abe JI, Le NT. Premature senescence and cardiovascular disease following cancer treatments: mechanistic insights. Front Cardiovasc Med 10:1212174, 2023. e-Pub 2023. PMID: 37781317.
- Lipe DN, Chaftari P, Reyes-Gibby C, Palaskas NL. The evolving landscape of chimeric antigen receptor T-cell therapy associated cardiotoxicity. Am J Emerg Med 57:220-221, 2022. e-Pub 2022. PMID: 35246349.
- Yilmaz S, Grudzen CR, Durham DD, McNaughton C, Marcelin I, Abar B, Adler D, Bastani A, Baugh CW, Bernstein SL, Bischof JJ, Coyne CJ, Henning DJ, Hudson MF, Klotz A, Lyman GH, Madsen TE, Pallin DJ, Reyes-Gibby C, Rico JF, Ryan RJ, Shapiro NI, Swor R, Thomas CR, Venkat A, Wilson J, Yeung SJ, Caterino JM. Palliative Care Needs and Clinical Outcomes of Patients with Advanced Cancer in the Emergency Department. J Palliat Med 25(7):1115-1121, 2022. e-Pub 2022. PMID: 35559758.
- Bischof JJ, Elsaid MI, Bridges JFP, Rosko AE, Presley CJ, Abar B, Adler D, Bastani A, Baugh CW, Bernstein SL, Coyne CJ, Durham DD, Grudzen CR, Henning DJ, Hudson MF, Klotz A, Lyman GH, Madsen TE, Reyes-Gibby CC, Rico JF, Ryan RJ, Shapiro NI, Swor R, Thomas CR, Venkat A, Wilson J, Yeung SJ, Yilmaz S, Caterino JM. Characterization of older adults with cancer seeking acute emergency department care: A prospective observational study. J Geriatr Oncol. e-Pub 2022. PMID: 35718667.
- Lipe DN, Bourenane SS, Wattana MK, Gaeta S, Chaftari P, Cruz Carreras MT, Manzano JG, Reyes-Gibby C. A modified emergency severity index level is associated with outcomes in cancer patients with COVID-19. Am J Emerg Med 54:111-116, 2022. e-Pub 2022. PMID: 35152119.
- Lipe DN, Viets-Upchurch J, Hanna EY, Reyes-Gibby C, Chen SR, Elsayem A, Long B. Carotid blowout syndrome in the emergency department: a case report and review of the literature. J Emerg Med 62(3):e29-e34, 2022. e-Pub 2022. PMID: 35065858.
- Lipe D, Chaftari P, Reyes-Gibby C, Palaskas N. The evolving landscape of climeric antigen receptor T-cell therapy associated cardiotoxicity. The American Journal of Emrgency Medicine, 2022.
- Banerjee P, Olmsted-Davis EA, Deswal A, Nguyen MT, Koutroumpakis E, Palaskas NL, Lin SH, Kotla S, Reyes-Gibby C, Yeung SJ, Yusuf SW, Yoshimoto M, Kobayashi M, Yu B, Schadler K, Herrmann J, Cooke JP, Jain A, Chini E, Le NT, Abe JI. Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications. J Cardiovasc Aging 2, 2022. e-Pub 2022. PMID: 35801078.
- Ren JL, Rojo RD, Perez JVD, Yeung SJ, Hanna EY, Reyes-Gibby CC. Variations in pain prevalence, severity, and analgesic use by duration of survivorship: A cross-sectional study of 505 post-treatment head and neck cancer survivors. BMC Cancer 21(1):1304, 2021. e-Pub 2021. PMID: 34872526.
- Klotz AD, Caterino JM, Durham D, Felipe Rico J, Pallin DJ, Grudzen CR, McNaughton C, Marcelin I, Abar B, Adler D, Bastani A, Bernstein SL, Bischof JJ, Coyne CJ, Henning DJ, Hudson MF, Lyman GH, Madsen TE, Reyes-Gibby CC, Ryan RJ, Shapiro NI, Swor R, Thomas CR, Venkat A, Wilson J, Jim Yeung SC, Yilmaz S, Stutman R, Baugh CW. Observation Unit Use Among Patients with Cancer Following Emergency Department Visits: Results of a Multicenter Prospective Cohort from CONCERN. Acad Emerg Med. e-Pub 2021. PMID: 34811858.
- Yennurajalingam S, Astolfi A, Indio V, Beccaro M, Schipani A, Yu R, Shete S, Reyes-Gibby C, Lu Z, Williams JL, Yeun SC, Anderson AE, Biasco G, Bruera E. Genetic Factors Associated With Pain Severity, Daily Opioid Dose Requirement, and Pain Response Among Advanced Cancer Patients Receiving Supportive Care. J Pain Symptom Manage 62(4):785-795, 2021. e-Pub 2021. PMID: 33848569.
- Coyne CJ, Reyes-Gibby CC, Durham DD, Abar B, Adler D, Bastani A, Bernstein SL, Baugh CW, Bischof JJ, Grudzen CR, Henning DJ, Hudson MF, Klotz A, Lyman GH, Madsen TE, Pallin DJ, Rico JF, Ryan RJ, Shapiro NI, Swor R, Thomas CR, Venkat A, Wilson J, Yeung SJ, Caterino JM. Cancer pain management in the emergency department: a multicenter prospective observational trial of the Comprehensive Oncologic Emergencies Research Network (CONCERN). Support Care Cancer 29(8):4543-4553, 2021. e-Pub 2021. PMID: 33483789.
- Lipe DN, Elsayem A, Cruz-Carreras MT, Thomas J, Feliciano A, Ren J, Gaeta SM, Rajha E, Manasanch E, Kheder E, Brock P, Reyes-Gibby C. Characteristics of cancer patients with COVID-19 in a cancer hospital. Ann Palliat Med 10(2):1763-1771, 2021. e-Pub 2020. PMID: 33222454.
- Jian Wang, Cielito C. Reyes-Gibby, Sanjay Shete. An Approach to Analyze Longitudinal Zero-Inflated Microbiome Count Data Using Two-Stage Mixed Effects Models. Statistics in Bioscience 21(13):267-290, 2021.
- Yeung SJ, Qdaisat A, Chaftari P, Lipe D, Merlin J, Rajha E, Wechsler A, Sandoval M, Viets J, Al-Breiki A, Shah M, Pandey R, Kamal M, Khattab O, Toale K, Wattana M, Elsayem A, Gaeta S, Brock P, Reyes-Gibby C, Alagappan K. Diagnosis and Management of Immune-Related Adverse Effects of Immune Checkpoint Therapy in the Emergency Department. J Am Coll Emerg Physicians Open 1(6):1-23, 2020. e-Pub 2020. PMID: 33392573.
- Reyes-Gibby CC, Wang J, Zhang L, Peterson CB, Do KA, Jenq RR, Shelburne S, Shah DP, Chambers MS, Hanna EY, Yeung SJ, Shete S. Oral microbiome and onset of oral mucositis in patients with squamous cell carcinoma of the head and neck. Cancer 126(23):5124-5136, 2020. e-Pub 2020. PMID: 32888342.
- Qdaisat A, Wu W, Lin JZ, Al Soud R, Yang Z, Hu Z, Gao S, Wu CC, Liu X, Silvestre J, Hita AG, Viets-Upchurch J, Al Adwan S, Al Haj Qasem N, Cruz Carreras MT, Jacobson KL, Chaftari PS, Abdel-Razeq H, Reyes-Gibby CC, Jim Yeung SC. Clinical and Cancer-Related Predictors for Venous Thromboembolism in Cancer Patients Presenting to the Emergency Department. J Emerg Med 58(6):932-941, 2020. e-Pub 2020. PMID: 32376060.
- Sandoval M, Banala S, Cruz Carreras Cruz M, Lipe D, Yeung S, Ehab H, Todd K, Alagappan K, Reyes Gibby C. Hypertension and Emergency Department Visits by Patients with Head and Neck Center. Journal of Cardiology & Cardiovascular Therapy 16(1), 2020. e-Pub 2020.
- Hassan S, Wattana M, Reyes-Gibby C. Immune-Related Myocarditis Presenting as Shortness of Breath and Complete Heart Block in an Urothelial Cancer Patient Receiving Pembrolizumab: A Case Report. Journal of Clinical Review and Case Reports 5(4). e-Pub 2020.
- Reyes CC, Anderson KO, Gonzalez CE, Ochs HC, Wattana M, Acharya G, Todd KH. Depression and survival outcomes after emergency department cancer pain visits. BMJ Support Palliat Care 9(4):e36, 2019. e-Pub 2018. PMID: 30171043.
- Shah M, Jomaa MK, Ferrarotto R, Yeung SJ, Hanna EY, Reyes-Gibby CC. Serious immune-related adverse events in patients with head and neck cancer after checkpoint blockade: Systematic review. Head Neck 41(11):4036-4050, 2019. e-Pub 2019. PMID: 31414560.
- Adler D, Abar B, Durham DD, Bastani A, Bernstein SL, Baugh CW, Bischof JJ, Coyne CJ, Grudzen CR, Henning DJ, Hudson MF, Klotz A, Lyman GH, Madsen TE, Pallin DJ, Reyes-Gibby CC, Rico JF, Ryan RJ, Shapiro NI, Swor R, Thomas CR, Venkat A, Wilson J, Yeung SJ, Caterino JM. Validation of the Emergency Severity Index (Version 4) for the Triage of Adult Emergency Department Patients With Active Cancer. J Emerg Med 57(3):354-361, 2019. e-Pub 2019. PMID: 31353265.
- Caterino JM, Adler D, Durham DD, Yeung SJ, Hudson MF, Bastani A, Bernstein SL, Baugh CW, Coyne CJ, Grudzen CR, Henning DJ, Klotz A, Madsen TE, Pallin DJ, Reyes-Gibby CC, Rico JF, Ryan RJ, Shapiro NI, Swor R, Venkat A, Wilson J, Thomas CR, Bischof JJ, Lyman GH. Analysis of Diagnoses, Symptoms, Medications, and Admissions Among Patients With Cancer Presenting to Emergency Departments. JAMA Netw Open 2(3):e190979, 2019. e-Pub 2019. PMID: 30901049.
- El Majzoub I, Qdaisat A, Thein KZ, Win MA, Han MM, Jacobson K, Chaftari PS, Prejean M, Reyes-Gibby C, Yeung SJ. Adverse Effects of Immune Checkpoint Therapy in Cancer Patients Visiting the Emergency Department of a Comprehensive Cancer Center. Ann Emerg Med 73(1):79-87, 2019. e-Pub 2018. PMID: 29880440.
- Reyes-Gibby CC, Wang J, Yeung SJ, Chaftari P, Yu RK, Hanna EY, Shete S. Genome-wide association study identifies genes associated with neuropathy in patients with head and neck cancer. Sci Rep 8(1):8789, 2018. e-Pub 2018. PMID: 29884837.
- Bacorro WR, Balid-Atwell SA, Sogono PG, Escuadra CJT, Reyes-Gibby C, Que JC, Ortin TTS. Factors in sustained compliance to a symptom-reporting mobile application: implications for clinical implementation. Journal of Hospital Management and Health Policy 2(19), 2018.
- Yang Z, Yang R, Kwak MJ, Qdaisat A, Lin J, Begley CE, Reyes-Gibby CC, Yeung SJ. Oncologic emergencies in a cancer center emergency department and in general emergency departments countywide and nationwide. PLoS One 13(2):e0191658, 2018. e-Pub 2018. PMID: 29462166.
- Reyes CC, Anderson KO, Gonzalez CE, Ochs HC, Wattana M, Acharya G, Todd KH. Depression and survival in patients with cancer presenting to the emergency department for pain. BMJ Support Palliat Care, 2018. e-Pub 2018.
- Elsayem AF, Warneke CL, Reyes-Gibby CC, Page VD, Buffardi LJ, Brock PA, Chaftari P, Alagappan K. "Triple Threat" Conditions may predict mortality in patients with cancer presenting to Emergency Departments. ASCO Post, 2017.
- Banala SR, Yeung SJ, Rice TW, Reyes-Gibby CC, Wu CC, Todd KH, Peacock WF, Alagappan K. Discharge or admit? Emergency Department management of incidental pulmonary embolism in patients with cancer. Int J Emerg Med 10(1):19, 2017. e-Pub 2017. PMID: 28589462.
- Reyes-Gibby CC, Melkonian SC, Hanna EY, Yeung SJ, Lu C, Chambers MS, Banala SR, Gunn GB, Shete SS. Cohort Study of oncologic emergencies in patients with head and neck cancedr. Head Neck 39(6):1195-1204, 2017. e-Pub 2017. PMID: 28346771.
- Fadol AP, Mouhayar E, Reyes-Gibby CC. The Use of Cardiac Resynchronization Therapy in Cancer Patients with Heart Failure. J Clin Exp Res Cardiol 3(1):105-114, 2017. e-Pub 2017. PMID: 29962508.
- Reyes-Gibby CC, Melkonian SC, Wang J, Yu RK, Shelburne SA, Lu C, Gunn GB, Chambers MS, Hanna EY, Yeung SJ, Shete S. Identifying novel genes and biological processes relevant to the development of cancer therapy-induced mucositis: An informative gene network analysis. PLoS One 12(7):e0180396, 2017. e-Pub 2017. PMID: 28678827.
- Reyes-Gibby CC, Wang J, Silvas MR, Yu RK, Hanna EY, Shete S. Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients. Sci Rep 6:34206, 2016. e-Pub 2016. PMID: 27670397.
- Elsayem AF, Merriman KW, Gonzalez CE, Yeung SC, Chaftari PS, Reyes-Gibby C, Todd KH. Presenting Symptoms in the Emergency Department as Predictors of Intensive Care Unit Admissions and Hospital Mortality in a Comprehensive Cancer Center. J Oncol Pract 12(5):e554-63, 2016. e-Pub 2016. PMID: 27072570.
- Reyes-Gibby CC, Wang J, Silvas MR, Yu R, Yeung SC, Shete S. MAPK1/ERK2 as novel target genes for pain in head and neck cancer patients. BMC Genet 17:40, 2016. e-Pub 2016. PMID: 26872611.
- Reyes-Gibby CC, Anderson KO, Todd KH. Risk for Opioid Misuse Among Emergency Department Cancer Patients. Acad Emerg Med 23(2):151-8, 2016. e-Pub 2016. PMID: 26824227.
- Yang Z, Qdaisat A, Hu Z, Wagar EA, Reyes-Gibby C, Meng QH, Yeung SC. Cardiac Troponin is a Predictor of Septic Shock Mortality in Cancer Patients in an Emergency Department: A Retrospective Cohort Study. PLoS One 23(2):e0153492, 2016. e-Pub 2016. PMID: 27077648.
- Reyes-Gibby CC, Yuan C, Wang J, Yeung SC, Shete S. Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: Alcohol, smoking and opioid addiction. BMC Syst Biol 9:25, 2015. e-Pub 2015. PMID: 26044620.
- Reyes-Gibby CC, Wang J, Yeung SJ, Shete S. Informative gene network for chemotherapy-induced peripheral neuropathy. BioData Min 8:24, 2015. e-Pub 2015. PMID: 26269716.
- Reyes-Gibby CC, Anderson KO, Merriman KW, Todd KH, Shete SS, Hanna EY. Survival patterns in squamous cell carcinoma of the head and neck: Pain as an independent prognostic factor for survival. J Pain 15(10):1015-22, 2014. e-Pub 2014. PMID: 25043982.
- Yennurajalingam S, Kwon JH, Urbauer DL, Hui D, Reyes-Gibby CC, Bruera E. Consistency of symptom clusters among advanced cancer patients seen at an outpatient supportive care clinic in a tertiary cancer center. Palliat Support Care 11(6):1-8, 2013. e-Pub 2013. PMID: 23388652.
- Reyes-Gibby CC, Swartz MD, Yu X, Wu X, Yennurajalingam S, Anderson KO, Spitz MR, Shete S. Symptom Clusters of Pain, Depressed Mood, and Fatigue in Lung Cancer: Assessing the Role of Cytokine Genes. Support Care Cancer 21(11):3117-25, 2013. e-Pub 2013. PMID: 23852407.
- Yi JK, Anderson KO, Le YC, Escobar-Chaves SL, Reyes-Gibby CC. English Proficiency, Knowledge and Receipt of HPV Vaccine in Vietnamese-American Women. J Community Health 38(5):805-11, 2013. e-Pub 2013. PMID: 23526096.
- Que JC, Sy Ortin TT, Anderson KO, Gonzalez-Suarez CB, Feeley TW, Reyes-Gibby CC. Depressive symptoms among cancer patients in a Philippine tertiary hospital: prevalence, factors, and influence on health-related quality of life. J Palliat Med 16(10):1280-4, 2013. e-Pub 2013. PMID: 24047452.
- Reyes-Gibby CC, Wang J, Spitz M, Wu X, Yennurajalingam S, Shete S. Genetic Variations in Interleukin-8 and Interleukin-10 are Associated With Pain, Depressed Mood, and Fatigue in Lung Cancer Patients. J Pain Symptom Manage 46(2):161-72, 2013. e-Pub 2012. PMID: 23149083.
- Liao Z, Hao J, Guo Y, Reyes-Gibby C, Guo H. Assessment of Cancer Pain Management Knowledge in Southwest China: A Survey of 259 Physicians from Small City and County Hospitals. J Palliat Med 16(6):692-5, 2013. e-Pub 2013. PMID: 23458651.
- Anderson KO, Reyes-Gibby CC. Biopsychosocial Approach to Persistent Post-Mastectomy Pain: What Can We Conclude?. Pain 154(5):623-4, 2013. e-Pub 2013. PMID: 23522928.
- Anderson KO, Reyes-Gibby CC . Biopsychosocial approach to persistent post-mastectomy pain: What can we conclude?. Pain 154(5):623-4, 2013. e-Pub 2013. PMID: 23522928.
- Dalal S, Hui D, Bidaut L, Lem K, Del Fabbro E, Crane C, Reyes-Gibby CC, Bedi D, Bruera E. Relationships among body mass index, longitudinal body composition alterations, and survival in patients with locally advanced pancreatic cancer receiving chemoradiation: a pilot study. J Pain Symptom Manage 44(2):181-91, 2012. e-Pub 2012. PMID: 22695045.
- Reyes-Gibby CC, Anderson KO, Morrow PK, Shete S, Hassan S. Depressive symptoms and health-related quality of life in breast cancer survivors. J Womens Health (Larchmt) 21(3):311-8, 2012. e-Pub 2011. PMID: 22060256.
- Reyes-Gibby CC, Anderson KO, Shete S, Bruera E, Yennurajalingam S. Early Referral to Supportive Care Specialists for Symptom Burden in Lung Cancer Patients: A Comparison of Non-Hispanic Whites, Hispanics, and Non-Hispanic Blacks. Cancer 118(3):856-63, 2012. e-Pub 2011. PMID: 21751190.
- Chen X, Gorlov IP, Ying J, Merriman KW, Kimmel M, Lu C, Reyes-Gibby CC, Gorlova OY. Initial medical attention on patients with early-stage non-small cell lung cancer. PLoS One 7(3):e32644, 2012. e-Pub 2012. PMID: 22412901.
- Yi JK, Swartz MD, Reyes-Gibby CC. English Proficiency, Symptoms, and Quality of Life in Vietnamese- and Chinese-American Breast Cancer Survivors. J Pain Symptom Manage 42(1):83-92, 2011. e-Pub 2011. PMID: 21227634.
- Yennurajalingam S, Urbauer DL, Casper KL, Reyes-Gibby CC, Chacko R, Poulter V, Bruera E. Impact of a Palliative Care Consultation Team on Cancer-Related Symptoms in Advanced Cancer Patients Referred to an Outpatient Supportive Care Clinic. J Pain Symptom Manage 41(1):49-56, 2011. e-Pub 2010. PMID: 20739141.
- Swartz MD, Peng B, Reyes-Gibby C, Shete S. Using Ascertainment for Targeted Resequencing to Increase Power to Identify Causal Variants. Stat Interface 4(3):285-94, 2011. PMID: 22468169.
- Reyes-Gibby C, Morrow PK, Bennett MI, Jensen MP, Shete S. Neuropathic pain in breast cancer survivors: Using the ID Pain as a screening tool. J Pain Symptom Manage 39(5):882-9, 2010. PMID: 20471548.
- Reyes-Gibby CC, Shete S, Yennurajalingam S, Frazier M, Bruera E, Kurzrock R, Crane CH, Abbruzzese J, Evans D, Spitz MR. Genetic and non-genetic covariates of pain severity in patients with adenocarcinoma of the pancreas: Assessing the influence of cytokine genes. J Pain Symptom Manage 38(6):894-902, 2009. e-Pub 2009. PMID: 19692203.
- Reyes-Gibby CC, Morrow PK, Buzdar A, Shete S. Chemotherapy-Induced Peripheral Neuropathy as a Predictor of Neuropathic Pain in Breast Cancer Patients Previously Treated with Paclitaxel. J Pain 10(11):1146-50, 2009. e-Pub 2009. PMID: 19595634.
- Reyes-Gibby CC, Spitz MR, Yennurajalingam S, Swartz M, Gu J, Wu X, Bruera E, Shete S. Role of inflammation gene polymorphisms on pain severity in lung cancer patients. Cancer Epidemiol Biomarkers Prev 18(10):2636-42, 2009. e-Pub 2009. PMID: 19773451.
- Reyes-Gibby CC, El Osta B, Spitz MR, Parsons H, Kurzrock R, Wu X, Shete S, Bruera E. The influence of tumor necrosis factor-alpha -308 G/A and IL-6 -174 G/C on pain and analgesia response in lung cancer patients receiving supportive care. Cancer Epidemiol Biomarkers Prev 17(11):3262-7, 2008. PMID: 18990769.
- Reyes-Gibby CC, Wu X, Spitz M, Kurzrock R, Fisch M, Bruera E, Shete S. Molecular epidemiology, cancer-related symptoms, and cytokines pathway. Lancet Oncol 9(8):777-85, 2008. PMID: 18672213.
- Torres-Vigil I, Aday LA, Reyes-Gibby C, De Lima L, Herrera AP, Mendoza T, Cleeland CS. Health care providers' assessments of the quality of advanced-cancer care in Latin American medical institutions: a comparison of predictors in five countries: Argentina, Brazil, Cuba, Mexico, and Peru. J Pain Palliat Care Pharmacother 22(1):7-20, 2008. PMID: 19042817.
- Reyes-Gibby CC, Spitz M, Wu X, Merriman K, Etzel C, Bruera E, Kurzrock R, Shete S. Cytokine genes and pain severity in lung cancer: exploring the influence of TNF-alpha-308 G/A IL6-174G/C and IL8-251T/A. Cancer Epidemiol Biomarkers Prev 16(12):2745-51, 2007. PMID: 18086782.
- Reddy S, Bruera E, Pace E, Zhang K, Reyes-Gibby CC. Clinically important improvement in the intensity of fatigue in patients with advanced cancer. J Palliat Med 10(5):1068-75, 2007. PMID: 17985963.
- Reyes-Gibby CC, Chan W, Abbruzzese JL, Xiong HQ, Ho L, Evans DB, Varadhachary G, Bhat S, Wolff RA, Crane C. Patterns of Self-reported Symptoms in Pancreatic Cancer Patients Receiving Chemoradiation. J Pain Symptom Manage 34(3):244-252, 2007. e-Pub 2007. PMID: 17513082.
- Reyes-Gibby CC, Shete S, Rakvåg T, Bhat SV, Skorpen F, Bruera E, Kaasa S, Klepstad P. Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. Pain 130(1-2):25-30, 2007. e-Pub 2006. PMID: 17156920.
- Reyes-Gibby CC, Aday LA, Todd KH, Cleeland CS, Anderson KO. Pain in aging community-dwelling adults in the United States: non-Hispanic whites, non-Hispanic blacks, and Hispanics. J Pain 8(1)(1):75-84, 2007. e-Pub 2006. PMID: 16949874.
- Reyes-Gibby CC, Aday LA, Anderson KO, Mendoza TR, Cleeland CS. Pain, depression, and fatigue in community-dwelling adults with and without a history of cancer. J Pain Symptom Manage 32(2)(2):118-128, 2006. PMID: 16877179.
- Reyes-Gibby CC, Ba Duc N, Phi Yen N, Hoai Nga N, Van Tran T, Guo H, Bhat S, Cleeland C. Status of cancer pain in Hanoi, Vietnam: A hospital-wide survey in a tertiary cancer treatment center. J Pain Symptom Manage 31(5)(5):431-439, 2006. PMID: 16716873.
- Cleeland C, Griesing T, Backonja M, Moskowitz R, Frey WD, Mekhail NA, Millea PJ, Nicholson BD, Reyes-Gibby, CC, Staats PS, Stockbridge H, Sunshine A, Brandenburg N, Goudie AR, Irish W, McLeod L, Whalen E. Development and testing of a neuropathic pain screening questionnaire: ID Pain. Curr Med Res Opin 22:1555-1565, 2006.
- Reyes-Gibby CC, Aday LA. Access to health care in a rural area of the Philippines. Ethn Dis 15(1)(1):104-109, 2005. PMID: 15720056.
- Weinstein SM, Romanus D, Lepisto EM, Reyes-Gibby C, Cleeland C, Greene R, Muir C, Niland J. Documentation of pain in comprehensive cancer centers in the United States: A preliminary analysis. J Natl Compr Canc Netw 2(2)(2):173-180, 2004. PMID: 19777706.
- Wang XS, Di LJ, Reyes-Gibby CC, Guo H, Liu SJ, Cleeland CS. End-of-life care in urban areas of China: a survey of sixty oncology clinicians. J Pain Symptom Manage 27(2)(2):125-130, 2004. PMID: 15157036.
- Cleeland CS, Reyes-Gibby CC, Schall M, Nolan K, Paice J, Rosenberg JM, Tollett JH, Kerns RD. Rapid improvement in pain management: the Veterans Health Administration and the Institute for Healthcare Improvement Collaborative. Clin J Pain 19(5)(5):298-305, 2003. PMID: 12966255.
- Reyes-Gibby CC, Mendoza TR, Wang S, Anderson KO, Cleeland CS. Pain and fatigue in community-dwelling adults. Pain Med 4(3)(3):231-237, 2003. PMID: 12974822.
- Yi J, Reyes-Gibby CC. Breast cancer screening practices among low-income Vietnamese women. International Quarterly of Community Health Education 21(1):41-49, 2003.
- Reyes-Gibby CC, McCrory LL, Cleeland CS. Variations in patients' self-report of pain by treatment setting. J Pain Symptom Manage 25(5)(5):444-448, 2003. PMID: 12727042.
- Anderson KO, Getto CJ, Mendoza TR, Palmer SN, Wang XS, Reyes-Gibby CC, Cleeland CS. Fatigue and sleep disturbance in patients with cancer, patients with clinical depression, and community-dwelling adults. J Pain Symptom Manage 25(5)(4):307-318, 2003. PMID: 12691682.
- Reyes-Gibby CC, Aday L, Cleeland C. Impact of pain on self-rated health in the community-dwelling older adults. Pain 95(1-2)(1-2):75-82, 2002. PMID: 11790469.
- Reyes-Gibby CC, Aday LA. Prevalence of and risk factors for hypertension in a rural area of the Philippines. J Community Health 25(5)(5):389-399, 2000. PMID: 10982012.
- Masaki Imanishi, Haizi Cheng, Sivareddy Kotla, Anita Deswal, MD, MPH, Nhat Tu Le, Eduardo Nunes Chini, Kyung Ae Ko, Venkata S K Samanthapudi, Ling-Ling Lee, Joerg Herrmann, Xiaolei Xu, Cielito Reyes-Gibby, Sai-Ching Jim Yeung, Keri Schadler, Syed Wamique Yusuf, Zhongxing Liao, Roza Nurieva, El-ad David Amir, Jared K Burks, Nicolas Palaskas, John Cooke, Steven H Lin, Michihiro Kobayashi, Momoko Yoshimoto, Jun-ichi Abe. Radiation therapy induces immunosenescence mediated by p90RSK. Frontiers in Cardiovascular Medicine, section Cardio-Oncology.
- Reyes-Gibby C, Qdaisat A,Lipe D, Abe J, Yeung S. A preliminary assessment of cardiotoxicities associated with immune-checkpoint inhibitor therapy.
Invited Articles
- Reyes-Gibby CC, Wu X, Spitz MR, Kurzrock R, Fisch M, Bruera E, Shete S. Molecular epidemiology, cancer-related systoms, and cytokines pathway. Lancet Oncol 9(8):777-785, 2008.
- Cleeland CS, Reyes-Gibby CC. When is it justified to treat symptoms? Measuring symptom burden. Oncology (Williston Park) 16 (9 Suppl 10)(9 Suppl 10):64-70, 2002. PMID: 12380956.
Manuals, Teaching Aids, Other Teaching Publications
- Reyes-Gibby CC. Breakthroughs and Challenges in the Management of Common Chronic Pain Conditions. Department of Health and Human Services Office of Women's Health, 2005.
Editorials
- Cleeland CS, Reyes-Gibby CC. Cancer-related Fatigue. Breast Diseases Quarterly 12(3):259-260, 2001.
Abstracts
- Hall AJ, Brock PA, Merriman KW, Page VD, Reyes-Gibby CC, Elsayem AF. Altered mental status and the role of neuroimaging in the Emergency Center of a comprehensive cancer center. European Delirium Association, Belgium, 2014.
- Reyes-Gibby CC , Shete S, Merriman K, Anderson KO, Todd KH, Hanna E. Pain and survival in patients with squamous cell cancer of head and neck (HNSCC): analysis of 2622 newly diagnosed HNSCC patients. J Pain, 2012.
- Reyes-Gibby C. A hospital-wide survey of cancer-related symptoms inn a tertiary cancer center in Manila, Phillipines. MASCC/ISOO, Athens, Greece, 2011.
- Reyes-Gibby C. Interleukin 1, IL-8, II-10, Tumor Necrosis Factor beta and Symptom Burden in Lung Cancer Patients. MASCC/ISOO, Athens, Greece, 2011.
- Reyes-Gibby C. Screening for Depression in Filipino Cancer Patients: Use of PHQ-8. MASCC/ISOO, Athens, Greece, 2011.
- Guadalupe R. Palos, Kai-Ping Liao, Araceli Garcia-Gonzalez, Katherine R. Ramsey, Karen O. Anderson, Cielito Reyes-Gibby. Disparities in Treatment-Related Symptoms of Cancer Survivors. Cancer Prevention Research Institute of Texas, 2010.
- Guadalupe R. Palos, Kai-Ping Liao, Araceli Garcia-Gonzalez, Katherine R. Ramsey, Karen O. Anderson, Cielito Reyes-Gibby. Caregiver Strain: Screening Caregivers for their Risk of Negative. Cancer Prevention Research Institute of Texas, 2010.
- Cielito C. Reyes-Gibby, DrPH, Karen O. Anderson,PhD, Sanjay Shete, PhD, Eduardo Bruera, MD, Sriram Yennurajalingam, MD. Early Referral to Supportive Care Specialists for Symptom Burden in Lung Cancer Patients: A Comparison of Non-Hispanic Whites, Hispanics, and Non-Hispanic Blacks. Cancer Prevention Research Institute of Texas, 2010.
- Reyes-Gibby CC, Spitz MR, Wu X, Kurzrock R, Shete S. Inflammation genes and pain severity in lung cancer. J Clin Oncol 27(15S):9618, 2009.
- Reyes-Gibby, CC, Morrow PK. Chemotherapy-induced peripheral neuropathy as a predictor of neuropathic pain in breast cancer patients previously treated with paclitaxel. J Clin Oncol 27:e20505, 2009.
- C.Reyes-Gibby, PK Morrow , Aman Buzdar , S. Shete. Chemotherapy-induced peripheral neuropathy as a predictor of neuropathic pain in. IMPAKKT, 2009.
- Cielito Reyes-Gibby, Sohela Hassan, Phuong Kanh Morrow , Aman Buzdar , Sanjay Shete. Depression and quality of life in breast cancer survivors:6-13 years post-chemotherapy. American Association of Cacner Research, 2009.
- Dalal S, Hui D, Bidaut L, Del Fabbro E, Reyes-Gibby CC, Bedi D, Lem K, Hess K, Crane CH, Bruera E. Differential impact of changes in muscle tissue (MT) and adipose tissue (AT) on survival in men and women with locally advanced pancreatic cancer (LAPC) receiving chemoradiation (CRT). American Society of Clinical Oncology, 2008.
- Reyes-Gibby CC, B. El Osta E, Spitz M, Parsons HA, Kurzrock R, Shete S, Bruera E. The influence of polymorphisms in cytokine genes on pain and response to analgesia in lung cancer patients receiving palliative treatment. American Society of Clinical Oncology, 2008.
- Reyes-Gibby CC, Spitz MR, Wu X, Merriman K, Etzel C, Kurzrock R, Shete S. Cytokine Polymorphisms and Pain in Lung Cancer. American Society of Preventive Oncology, Houston, TX, 2007.
- Reyes-Gibby, CC, Spitz MR, Wu X, Shete. Cytokine gene polymorphisms and cancer-related symptoms in lung cancer patients. J Clin Oncol 25(18S):9012, 2007.
- C.Reyes-Gibby, M. Frazier, J. Abbruzzese, C. Crane, R. Kurzrock, E. Bruera, S. Shete, D. Evans, M. Spitz. Cytokine gene polymorphisms and pain severity in patients with. International Association for the Study of Pain, 2007.
- Reyes-Gibby CC, Shete S, Rakvåg T, Bhat S, Skorpen F, Bruera E, Kaasa S, Klepstad P. Exploring gene joint effects and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. American Society for Human Genetics, New Orleans, 2006.
- Reyes-Gibby CC, Nguyen, BD, Nguyen, PY, Cleeland CS. Needs assessment for cancer pain relief programs in Vietnam: Prevalence of cancer pain in a state of art treatment center in Hanoi. International Association for the Study of Pain (IASP) 11th World Congress on Pain, Sydney, Australia, 2005.
- Reyes-Gibby CC, Cleeland CS. Pain, depression, and fatigue in community-dwelling populations with and without cancer. American Pain Society 23rd Annual Scientific Meeting (American Pain Society and Canadian Pain Society 2nd Joint Scientific Meeting), Vancouver BC, 2004.
- Reyes-Gibby CC, Anderson KO, Mendoza TR, Wang XS, Cleeland CS. Symptom burden in community-dwelling adults. 2nd Annual Conference on Mechanisms and Treatment of Cancer-related Symptoms, The University of Texas M. D. Anderson Cancer Center, Houston TX, 2004.
- Reyes-Gibby CC, Cleeland CS. Ethnic and racial differences in pain in aging populations. American Pain Society 22nd Annual Scientific Meeting, Chicago IL, 2003.
- Reyes-Gibby CC,. Developing a questionnaire on cultural beliefs: assessing hypertension in the Philippines. American Public Health Association 130th Annual Meeting, Philadelphia PA, 2002.
- Reyes-Gibby CC, Wang XS, Mendoza TR, Morrissey M, Wendt J, Anderson KO, Cleeland CS. Impact of pain on fatigue: community-dwelling and cancer patient populations. International Association for the Study of Pain (IASP) 10th World Congress on Pain, San Diego CA, 2002.
- Reyes-Gibby CC, McCrory LL, Cleeland CS. Variations in patients’ self reports of pain by treatment setting. American Pain Society 21st Annual Meeting, Baltimore MD, 2002.
Book Chapters
- Reyes-Gibby C, Ren Jenny. National and Institutional Research Efforts on Oncologic Emergencies: The Comprehensive Oncologic Emergencies Research Network (CONCERN) and the Program on Oncologic Emergency Medicine (POEM). In: Oncologic Emergency Medicine: Principles and Practice. 2nd ed, 915-933, 2021.
- Zhu X, Wang J, Reyes-Gibby C, Shete S. Statistical Approaches for Processing and Analyzing Microbiome Data. In: Statistical Human Genetics. 2nd, 2017.
- Zhu X, Wang J, Reyes-Gibby C, Shete S. Processing and Analyzing Human Microbiome Data. In: Methods Mol Biol. Springer Science + Business Media, 649-677, 2017.
- Reyes-Gibby CC, Anderson KO. Cancer Pain, Epidemiology. In: Encyclopedia of Pain. Springer-Verlag Berlin Heidelberg, 2013.
- Reyes-Gibby CC, Anderson KO. Cancer Pain Management, Patient-Related Barriers. In: Encyclopedia of Pain. Springer-Verlag Berlin Heidelberg, 2013.
- Reyes-Gibby CC, Torres-Vigil I, Croock R. Epidemiology of Pain: Classical and Molecular Approaches. In: Clinical Pain Management 2E: Chronic volume, 2008.
- Reyes-Gibby CC. Cancer pain management: patient-related barriers. In: Encyclopedic Reference on Pain. Springer Verlag: New York, NY, USA, 2007.
- Reyes-Gibby CC, Cleeland CS. Pain Epidemiology. In: Encyclopedic Reference on Pain. Springer Verlag: Berlin, 2007.
- Reyes-Gibby CC, Cleeland CS. Epidemiology of pain and cancer-related symptoms. In: Acute Care of the Cancer Patient. Marcel Dekker, Inc, 1031-1039, 2006.
- Aday LA, Quill BE, Reyes-Gibby CC. Equity in Rural Health and Health Care. In: Handbook of Rural Health. Plenum: New York, 45-72, 2001.
- Reyes-Gibby C and Palos GR. Pain, aging, and ethnicity. In: Culture, genes, and analgesia: Understanding and managing pain in diverse populations. Oxford University Press: New York, New York.
Letters to the Editor
- Reyes-Gibby CC, Todd KH. Oligo-Evidence for Oligoanalgesia: A Non-Sequitur?. Ann Emerg Med Mar;61(3): 373-4, 2013.
Grant & Contract Support
| Title: | Gene Polymorphisms and Symptoms in Lung Cancer Patients |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator |
| Title: | Needs Assessment for Cancer Pain Relief Programs in Three Cancer Centers in Vietnam |
| Funding Source: | US Cancer Pain Relief Committee |
| Role: | Principal Investigator |
| Title: | National Survey of Pain in the US |
| Funding Source: | American Pain Foundation |
| Role: | Co-Investigator |
| Title: | Multi-Center Pilot Evaluation of Pain Management and Outcomes within the National Comprehensive Cancer Network (NCCN), |
| Funding Source: | National Comprehensive Cancer Network (NCCN) |
| Role: | Principal Investigator |
| Title: | Neuropathic Pain in Breast Cancer Survivors |
| Funding Source: | Pfizer Inc |
| Role: | Principal Investigator |
| Title: | Cytokine Polymorphisms and Symptoms |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator |
| Title: | Consulting Agreement with St. Jude Children's Research Hospital |
| Funding Source: | St. Jude Children's Research Hospital |
| Role: | Consultant |
| Title: | Molecular Epidemiology of Neuropathic Pain in Head and Neck Cancer |
| Funding Source: | NIH/NIDCR |
| Role: | Principal Investigator |
| Title: | Risk of opioid misuse and the management of chronic cancer pain in the Emergency Department |
| Funding Source: | Emergency Medicine Foundation and the Emergency Medicine Patient Safety Foundation |
| Role: | Co-Investigator |
| Title: | High Density Association Analysis for Lung Cancer |
| Funding Source: | NIH/NCI |
| Role: | Co-Investigator |
| Title: | The Emergency Department Pain Registry: Impact Evaluation of the 2012 American College of Emergency Physicians Opioid Prescribing Guidelines |
| Funding Source: | Pfizer |
| Role: | Co-Principal Investigator |
| Title: | Collaborative Science: Epidemiology of Neuropathic Pain in Minority Head and Neck Cancer Patients |
| Funding Source: | NIH/NIDCR |
| Role: | Principal Investigator |
| Title: | IComPaSs |
| Funding Source: | Conquer Cancer Foundation and ASCO |
| Role: | Co-Investigator |
| Title: | Composition and Temporal Changes of the Oral Microbiome in Head and Neck Cancer Patients at High Risk for Oral Mucositis |
| Funding Source: | NIH/NIDCR |
| Role: | Principal Investigator |
| Title: | Improving emergency care and outcomes of immune-related adverse events: The immune-related emergency disposition index (IrEDi) |
| Funding Source: | NIH/NCI |
| Role: | Principal Investigator |
| Title: | Opioid-induced constipation in cancer patients |
| Funding Source: | Salix |
| Role: | Co-Investigator |
Patient Reviews
CV information above last modified August 30, 2024