Cynthia R. Lockworth, DVM, DACLAM
Department of Veterinary Medicine and Surgery, Division of Discovery Science
Present Title & Affiliation
Primary Appointment
Professor, Department of Veterinary Medicine and Surgery, Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 1998 | Texas A&M University, College Station, Texas, US, Doctor of Veterinary Medicine, DVM |
| 1995 | Texas A&M University, College Station, Texas, US, Veterinary Science, BS |
| 1995 | University of Houston, Houston, Texas, US, Anthropology, BS |
| 1995 | University of Houston, Houston, Texas, US, Bioscience, BS |
Postgraduate Training
| 2005-2007 | Clinical Fellowship, Laboratory Animal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas |
Board Certifications
| 2017 | Diplomate, American College of Laboratory Animal Medicine |
Experience & Service
Academic Appointments
Associate Professor, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - 2023
Assistant Professor, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, 2011 - 2017
Instructor, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2007 - 2011
Administrative Appointments/Responsibilities
Section Chief, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - Present
Section Chief ad interim, Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2017
Other Appointments/Responsibilities
Clinical Veterinarian, Petvet Animal Hospital, Houston, TX, 2001 - 2005
Clinical Veterinarian, Voss Road Animal Hospital, Houston, TX, 2000 - 2001
Clinical Veterinarian, Grant Road Animal Clinic, Houston, TX, 1998 - 2000
Institutional Committee Activities
Member, Faculty Academic Review Committee, 2022 - Present
Voting member, Mid-Career Faculty Committee, 2021 - Present
Committee member, Veterinary Medicine & Surgery Chair Advisory Committee, 2018 - 2019
Alternate member, Institutional Animal Care and Use Committee, 2017 - Present
Alternate member, Radiation Safety Committee, 2017 - Present
Senator, Faculty Senate, 2015 - 2018
Member, Faculty Academic Review Committee, 2015 - 2018
Voting member, Institutional Biosafety Committee, 2014 - Present
Voting member, Radiation Safety Committee, 2013 - 2017
Alternate member, Institutional Biosafety Committee, 2013 - 2014
Alternate member, Radiation Safety Committee, 2009 - 2013
Alternate member, Institutional Animal Care and Use Committee, 2008 - 2015
Honors & Awards
| Outstanding Clinical Veterinarian Award, Charles Rivers Laboratories | |
| Letter of Commendation, Institutional Animal Care and Use Committee, MD Anderson Cancer Center | |
| First Place Poster in Animal Welfare, Training, and the 3Rs, American Association of Laboratory Animal Science National Meeting | |
| First Place Poster in Animal Husbandry/Management, American Association of Laboratory Animal Science National Meeting |
Selected Publications
Peer-Reviewed Articles
- Tatara AM, Wurster S, Lockworth CR, Albert ND, Walsh TJ, Mikos AG, Eisenhoffer GT, Kontoyiannis DP. Immunosuppressed Adult Zebrafish Model of Mucormycosis. Antimicrob Agents Chemother 62(11), 2018. e-Pub 2018. PMID: 30150461.
- Hayes-Jordan AA, Ma X, Menegaz BA, Lamhamedi-Cherradi SE, Kingsley CV, Benson JA, Camacho PE, Ludwig JA, Lockworth CR, Garcia GE, Craig SL. Efficacy of ONC201 in Desmoplastic Small Round Cell Tumor. Neoplasia 20(5):524-532, 2018. e-Pub 2018. PMID: 29626752.
- Lockworth CR, Rodriguez T, Schmit MS, Hill LR. The Power of a Positive Approach to Realizing Change in an Animal Facility. Lab Anim (NY) 47(3):59, 2018. PMID: 29483686.
- Kendricks AL, Pageon LR, Craig SL, Wen Y, Sood AK, Lockworth CR. Pathology in Practice: Severe Polyarthritis with Implanted Ovarian Carcinoma Cells in a Mouse. J Am Vet Med Assoc 249(10):1149-1151, 2016. PMID: 27823375.
- Lockworth CR, Kim SJ, Liu J, Palla SL, Craig SL. Effect of Enrichment Devices on Aggression in Manipulated Nude Mice. J Am Assoc Lab Anim Sci 54(5):731-6, 2015. PMID: 26632782.
- Monts de Oca NA, Laughlin M, Jenkins J, Lockworth CR, Bolton ID, Brammer DW. Comparison of Indoor Air Quality between 2 Ventilation Strategies in a Facility Housing Rhesus Macaques (Macaca mulatta). J Am Assoc Lab Anim Sci 54(5):527-35, 2015. PMID: 26424251.
- Matthias N, Robinson MA, Crook R, Lockworth CR, Goodwin BS. Local cryoanalgesia is effective for tail-tip biopsy in mice. J Am Assoc Lab Anim Sci 52(2):171-5, 2013. PMID: 23562100.
- Lamothe B, Lai Y, Hur L, Orozco NM, Wang J, Campos AD, Xie M, Schneider MD, Lockworth CR, Jakacky J, Tran D, Ho M, Dawud S, Dong C, Lin HK, Hu P, Estrov Z, Bueso-Ramos CE, Darnay BG. Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice. PLoS One 7(12):e51228, 2012. e-Pub 2012. PMID: 23251462.
- Matthias N, Lockworth CR, Zhang F, Lee MH, Yeung SC, Tsai KY, Hamir AN. Multiple cystic sweat gland tumors in transgenic mice. Comp Med 62(1):27-30, 2012. PMID: 22330648.
- Tran QT, Lockworth CR, Craig SL. Managing a pending IBC approval. IBC approval not substantive. Lab Anim (NY) 40(10):296-8, 2011. e-Pub 2011. PMID: 22358203.
- Lockworth CR, Craig SL, Liu J, Tinkey PT. Training veterinary care technicians and husbandry staff improves animal care. J Am Assoc Lab Anim Sci 50(1):84-93, 2011. PMID: 21333169.
Invited Articles
- Wilson LA, Miller JJ, Work RK, Piotrowski SL, Kasper FK, Young S, Lai SY, Lockworth CR, Hill LR. Novel Diet Regimen for lagomorphs in a Compromised Oral Wound Healing Study. Laboratory Animal Science Professional, 2018. PMID: None.
- Lockworth CR, Monts de Oca NA. Training Toolbox: The Constructs of an Effective Training Program in Animal Health. ALN None(None):None, 2017. e-Pub 2017. PMID: None.
- Lockworth CR. A case of chronic regurgitation in a pig. ACTS Newsletter None(None):None, 2013. PMID: None.
- Craig S, Lockworth C, Naff K. Questions for the investigator. Monitor matters. Lab Anim (NY) 35(9):16-7, 2006. PMID: 17008901.
Manuals, Teaching Aids, Other Teaching Publications
- Lockworth CR, Oca MD, NA. Common Rodent Health Conditions of Mice. American Association of Laboratory Animal Science, AALAS Learning Library, 2021.
- Lockworth CR, Monts de Oca NA. Rodent Clinical Conditions Library. Charles River Laboratories, 2017.
- Lockworth CR, Monts de Oca NA. Common Rodent Health Conditions Poster. Charles River Laboratories, 2015.
- Lockworth CR. Algorithm for Anesthetic Emergencies in Large Animals. American Association of Laboratory Animal Conference, 2013.
- Lockworth CR. Rodent Health Management Algorithm. Internal/MDA, 2009.
Other Articles
- Pesek, Lockworth CR Management of a Water Outage in a Large Rodent Facility. Laboratory Animal Science Professional None(None):None, 2022. PMID: None.
- Rodriguez E, Duran A, Rodriguez Jr T, Collins T, Lockworth CR Sign of the Times: Saving the Lives of Mice. Laboratory Animal Science Professional, 2017. PMID: None.
- Lockworth, CR, Monts de Oca N Rodent Health: A Picture is Worth a Thousand Words. Laboratory Animal Science Professional 4(2):46-47, 2016. PMID: None.
Selected Presentations & Talks
Local Presentations
- 2020. Aquatic animals: review of housing, husbandry, and relevant IACUC topics. None. University of Houston IACUC. Houston, Texas, US.
- 2020. Leadership academy. None. Texas Branch American Association for Laboratory Animal Science. San Marcos, Texas, US.
- 2017. A training tale: Construction of a rodent health training program. Conference. UTMD Anderson Cancer Center. Houston, TX, US.
- 2017. The A to Z of rodent health conditions. Conference. Texas Branch American Association for Laboratory Animal Science. Houston, TX, US.
- 2017. Implements of education: the building blocks of an effective rodent health training program. Conference. Texas Branch American Association for Laboratory Animal Science. Houston, TX, US.
- 2011. Training program forges a path to improved animal health. Conference. UTMD Anderson Cancer Center. Houston, TX, US.
- 2006. Case presentation: blood gas analysis in swine. None. Texas Branch American Association for Laboratory Animal Science. College Station, Texas, US.
Regional Presentations
- 2020. Leadership Academy. Conference. TBAALAS. San Marcos, TX, US.
- 2019. High and Dry: Navigating the Waters of a Water Outage. Conference. TBAALAS. Arlington, TX, US.
- 2006. Blood Gas Analysis in Swine. Conference. Texas Branch American Association for Laboratory Animal Science. San Antonio, TX, US.
- 2006. Case Presentation: Blood Gas Analysis in Swine. Conference. Texas Branch American Association for Laboratory Animal Science. College Station, TX, US.
National Presentations
- 2024. Novel Method of Corticosterone Collection to Assess Stress at Different Population Densities in Xenopus laevis. Poster. American Association of Laboratory Animal Science Conference. Nashville, Tennessee, US.
- 2020. Working without Water: How to successfully manage a water outage in a vivarium. Conference. American Association of Laboratory Animal Science Conference. Virtual (formerly Charlotte, NC), US.
- 2019. Glass Half Full: Hydrating Mice without Water. Conference. American Association for Laboratory Animal Science Conference. Denver, CO, US.
- 2019. When your Mouse House is Dry: Strategies and Solutions for the Successful Management of a water Outage. Conference. Techniplast Conference of Excellence. Salt Lake City, UT, US.
- 2017. Hopping towards the future. None. American Association of Laboratory Animal Science Conference. Austin, Texas, US.
- 2017. Behavior modification of personnel through the use of positive reinforcement. Conference. American Association of Laboratory Animal Science Conference. Austin, TX, US.
- 2017. Food for Thought: Changing Feeding Practices Improves Efficiency. Conference. American Association of Laboratory Animal Science Conference. Austin, TX, US.
- 2017. Rodent health: An illustrative compendium for the identification and management of clinical conditions in mice. Invited. Charles River Laboratories. Mashantucket, CT, US.
- 2016. Tools of the training trade: mechanics of improved animal health. Conference. American Association of Laboratory Animal Science Conference. Charlotte, NC, US.
- 2016. Evolution of a nonhuman primate enrichment program. None. American Association of Laboratory Animal Science Conference. Charlotte, North Carolina, US.
- 2016. Identification and Management of Common Clinical Conditions in Laboratory Rodents. Invited. Charles River Short Course. Providence, RI, US.
- 2014. Anatomy of a technician training program. Conference. American Association of Laboratory Animal Science Conference. San Antonio, TX, US.
- 2014. Anatomy of a Laboratory Animal Training Program. Conference. American Association of Laboratory animal Science Conference. San Antonio, TX, US.
- 2013. Algorithm for Veterinary Anesthetic Emergencies in the Laboratory Animal Setting. Poster. American Association of Laboratory Animal Science Conference. Baltimore, Maryland, US.
- 2013. Anesthetic Emergency Algorithms for Improved Crises Management. Conference. American Association for Laboratory Animal Science Conference. Baltimore, MD, US.
- 2011. Animal Care Training in the Face of Colony Expansion. Conference. American Association of Laboratory Animal Science Conference. San Diego, CA, US.
- 2011. Veterinary staff training program improves animal health. Conference. ACLAM Forum. Newport, RI, US.
- 2010. Xenopus Zebra. Conference. American Veterinary Medical Association. Atlanta, GA, US.
International Presentations
- 2018. Common Rodent Health Conditions: Practical Tips for Identification and Management. Invited. TALAS. Bankok, TH.
Formal Peers
- 2019. Aquatic animals: Review of Housing, Husbandry, and relevant IACUC topics. Invited. University of Houston. Houston, Texas, US.
Grant & Contract Support
| Title: | Cancer Center Support (CORE) Grant |
| Funding Source: | NIH/NCI |
| Role: | Other personnel |
| Title: | Standardization of husbandry practices in Xenopus laevis using the corticosterone stress response |
| Funding Source: | American Association for Laboratory Animal Science |
| Role: | PI |
| Title: | The Gulf Coast Consortium Veterinary Training Program in Comparative Medicine |
| Funding Source: | NIH/NCRR |
| Role: | Veterinary Mentor |
| Title: | Standardization of husbandry practices in Xenopus laevis using the corticosterone stress response |
| Funding Source: | ACLAM Foundation |
| Role: | PI |
| Title: | Molecular Dissection of host–environment interaction in gastric tumorigenesis |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
Patient Reviews
CV information above last modified November 24, 2024